JP2015083582A5 - - Google Patents
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- JP2015083582A5 JP2015083582A5 JP2014247793A JP2014247793A JP2015083582A5 JP 2015083582 A5 JP2015083582 A5 JP 2015083582A5 JP 2014247793 A JP2014247793 A JP 2014247793A JP 2014247793 A JP2014247793 A JP 2014247793A JP 2015083582 A5 JP2015083582 A5 JP 2015083582A5
- Authority
- JP
- Japan
- Prior art keywords
- suspension
- less
- volume
- suspension according
- gauge needle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Claims (6)
- タンパク質濃度が２００ｍｇ／ｍＬ以上であり、かつ粘度が５０センチポアズ未満である、対象への皮下送達に用いるためのタンパク質粒子の懸濁液。
- 送達が、２１〜２７ゲージの針を備える注射器を用いて達成される、請求項１に記載の懸濁液。
- 注射器が２５〜２７ゲージの針を備える、請求項２に記載の懸濁液。
- 体積が５ｍＬ以下である、請求項１〜３のいずれか１項に記載の懸濁液。
- 体積が１．５ｍＬ以下である、請求項１〜３のいずれか１項に記載の懸濁液。
- タンパク質粒子がサブミクロンサイズの粒子である、請求項１〜５のいずれか１項に記載の懸濁液。
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11508008P | 2008-11-16 | 2008-11-16 | |
| US61/115,080 | 2008-11-16 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011536414A Division JP5711138B2 (ja) | 2008-11-16 | 2009-11-10 | 高濃度の低粘度懸濁液 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015083582A JP2015083582A (ja) | 2015-04-30 |
| JP2015083582A5 true JP2015083582A5 (ja) | 2015-07-02 |
Family
ID=42170660
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011536414A Expired - Fee Related JP5711138B2 (ja) | 2008-11-16 | 2009-11-10 | 高濃度の低粘度懸濁液 |
| JP2014247793A Pending JP2015083582A (ja) | 2008-11-16 | 2014-12-08 | 高濃度の低粘度懸濁液 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011536414A Expired - Fee Related JP5711138B2 (ja) | 2008-11-16 | 2009-11-10 | 高濃度の低粘度懸濁液 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US8779094B2 (ja) |
| EP (1) | EP2376522A4 (ja) |
| JP (2) | JP5711138B2 (ja) |
| KR (1) | KR20110103961A (ja) |
| CA (1) | CA2743789C (ja) |
| IL (1) | IL212919A (ja) |
| WO (1) | WO2010056657A2 (ja) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5658031B2 (ja) | 2007-06-22 | 2015-01-21 | ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム | 薄膜凍結による安定したサブミクロンのペプチド又はタンパク質粒子の形成 |
| EP2544721B1 (en) * | 2010-03-09 | 2017-12-06 | Janssen Biotech, Inc. | Non-aqueous high concentration reduced viscosity suspension formulations |
| US9072668B2 (en) | 2010-03-09 | 2015-07-07 | Janssen Biotech, Inc. | Non-aqueous high concentration reduced viscosity suspension formulations of antibodies |
| US20110223208A1 (en) * | 2010-03-09 | 2011-09-15 | Beth Hill | Non-Aqueous High Concentration Reduced Viscosity Suspension Formulations |
| US9445990B2 (en) * | 2010-10-06 | 2016-09-20 | Medtronic, Inc. | TNF inhibitor formulation for use in implantable infusion devices |
| AU2012225277A1 (en) * | 2011-03-10 | 2013-09-26 | Board Of Regents, The University Of Texas System | Protein nanoparticle dispersions |
| CN104023748B (zh) * | 2011-10-28 | 2018-03-02 | 诚信生物公司 | 含有氨基酸的蛋白质制剂 |
| US9737662B2 (en) | 2011-11-07 | 2017-08-22 | Battelle Memorial Institute | Processes for delivery of viscous drug therapies |
| TR201810930T4 (tr) * | 2012-05-18 | 2018-08-27 | Genentech Inc | Yüksek konsantrasyonlu monoklonal antikor formülasyonları. |
| US20140342006A1 (en) * | 2013-03-15 | 2014-11-20 | Ansun Biopharma, Inc. | Methods for Preparing Injectable Protein Microparticle Suspensions |
| IL312865B1 (en) | 2013-09-11 | 2025-02-01 | Eagle Biologics Inc | Liquid protein formulations containing viscosity-reducing agents |
| CN103976947B (zh) * | 2014-06-05 | 2016-08-17 | 段明星 | 一种含酶油悬浮剂及其制备方法与应用 |
| SG11201702614SA (en) * | 2014-10-01 | 2017-04-27 | Eagle Biolog Inc | Polysaccharide and nucleic acid formulations containing viscosity-lowering agents |
| JP5774190B1 (ja) * | 2014-12-12 | 2015-09-09 | ジーンメディカル株式会社 | 皮下注射用剤及び皮下注射用剤を含有する注射器の製造方法 |
| EP3231433B1 (en) | 2014-12-12 | 2023-12-27 | Motejo. Ltd | Agent for hypodermic injection |
| MA46466A (fr) | 2016-10-06 | 2019-08-14 | Amgen Inc | Formulations pharmaceutiques de protéines à viscosité réduite |
| US11654112B2 (en) | 2016-11-22 | 2023-05-23 | Elektrofi, Inc. | Particles comprising a therapeutic or diagnostic agent and suspensions and methods of use thereof |
| KR102051808B1 (ko) | 2018-07-23 | 2019-12-04 | 주식회사 종근당 | 테스토스테론 운데카노에이트를 포함하는 안정한 약제학적 조성물 |
| EP3917500A2 (en) | 2019-01-31 | 2021-12-08 | Elektrofi, Inc. | Particle formation and morphology |
| AU2020219125A1 (en) | 2019-02-05 | 2021-08-12 | Lindy Biosciences, Inc. | Isolated cell culture components and methods for isolating the same from liquid cell culture medium |
| US20200376128A1 (en) * | 2019-06-01 | 2020-12-03 | Lupin Holdings B.V. | Monodisperse resorbable polyester polymer compositions, systems, and methods |
| CN114514035A (zh) * | 2019-09-13 | 2022-05-17 | 伊勒卓菲公司 | 递送用于治疗疾病的治疗性生物制剂的组合物和方法 |
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| BE795516A (fr) | 1972-02-17 | 1973-08-16 | Ciba Geigy | Preparations de peptides huileuses et injectables et procede pour leur preparation |
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| EP0079143A3 (en) | 1981-10-20 | 1984-11-21 | Adnovum Ag | Pseudoplastic gel transfer |
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| US5411951A (en) | 1984-10-04 | 1995-05-02 | Monsanto Company | Prolonged release of biologically active somatotropin |
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| SE465950B (sv) | 1989-10-23 | 1991-11-25 | Medinvent Sa | Kombination av ett aggregat partikelformat, kristallint eller frystorkat laekemedel med en pseudoplastisk gel foer beredning av ett injicerbart preparat samt foerfarande foer dess framstaellning |
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| US7651770B2 (en) | 2005-12-16 | 2010-01-26 | The University Of Kansas | Nanoclusters for delivery of therapeutics |
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| CN101081882A (zh) * | 2007-07-06 | 2007-12-05 | 天津大学 | 大分子印迹交联聚乙烯基吡咯烷酮微球及低温悬浮聚合制备方法 |
| JP2009173610A (ja) | 2008-01-28 | 2009-08-06 | Fujifilm Corp | タンパク質ナノ粒子 |
| RU2496482C2 (ru) | 2008-03-05 | 2013-10-27 | Бакстер Интернэшнл Инк. | Композиции и способы для доставки лекарственных средств |
| EP2285825B1 (en) | 2008-05-09 | 2020-07-15 | South Dakota State University | Method of forming non-immunogenic hydrophobic protein nanoparticles and uses therefor |
| US20100009007A1 (en) | 2008-07-10 | 2010-01-14 | Baxter International Inc. | Non-covalent modification of microparticles and process of preparing same |
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-
2009
- 2009-11-10 US US13/129,283 patent/US8779094B2/en active Active
- 2009-11-10 EP EP09826617.4A patent/EP2376522A4/en not_active Withdrawn
- 2009-11-10 CA CA2743789A patent/CA2743789C/en active Active
- 2009-11-10 KR KR1020117013867A patent/KR20110103961A/ko not_active Application Discontinuation
- 2009-11-10 WO PCT/US2009/063852 patent/WO2010056657A2/en active Application Filing
- 2009-11-10 JP JP2011536414A patent/JP5711138B2/ja not_active Expired - Fee Related
-
2011
- 2011-05-16 IL IL212919A patent/IL212919A/en active IP Right Grant
-
2014
- 2014-06-05 US US14/297,403 patent/US20140378370A1/en not_active Abandoned
- 2014-12-08 JP JP2014247793A patent/JP2015083582A/ja active Pending
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