JP2012249805A - Image generation device, radiographic imaging system, image generation program, and image generation method - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide an image generation device, radiographic imaging system, image processing program, and image processing method for generating a tomographic image with which positional relation between an object of interest desired to be sampled and a sampling needle is appropriately confirmed.SOLUTION: When the kind of a biopsy needle 40 and the insertion direction of the biopsy needle 40 are designated, previously associated parameters are acquired as information of the biopsy needle 40 corresponding to the kind of the biopsy needle 40 and the insertion direction of the biopsy needle 40. Further, the position of a target is acquired. A slice interval determination part 68 determines a slice interval, on the basis of the position (a three-dimensional coordinate) of the target and the parameters. After the biopsy needle 40 is inserted to the breast N of a subject W, a radiographic imaging apparatus 10 captures a radiographic image. Reconstitution is performed with a plurality of the captured radiographic images at a determined slice interval, thereby to generate a tomographic image. The tomographic image is displayed on the display 82 of a display device 80.

Description

  The present invention relates to an image generation apparatus, a radiographic imaging system, an image generation program, and an image generation method, and more particularly to an image generation apparatus, a radiographic imaging system, and image generation for collecting a living body by inserting a biopsy needle into a subject. The present invention relates to a program and an image generation method.

  For the purpose of medical diagnosis, biopsy (biopsy, biopsy) is performed in which a part of an affected area of a patient is collected. In a biopsy, the positional relationship between a target (tissue such as a lesion) and a biopsy needle is confirmed using a radiographic image taken by a radiographic imaging device or a tomographic image obtained by tomosynthesis imaging. It has been broken.

  As a technique related to slice thickness for reconstructing a tomographic image, for example, Patent Document 1 discloses a technique for generating a tomographic image at a first slice interval or a finer second slice interval based on a region of interest. Is described.

JP 2008-110098 A

  Although there is a technique for making the slice thickness variable in this way, it may not be appropriate from the viewpoint of confirming the positional relationship between the target (tissue such as a lesion) and the biopsy needle when performing a biopsy. is there.

  For example, when confirming the positional relationship between a target (tissue such as a lesion) to be acquired using a tomographic image and a biopsy needle, if the slice thickness of the tomographic image is not appropriate, for example, the entire opening of the biopsy needle is not reflected In some cases, it may be difficult to confirm the positional relationship with the biopsy needle.

  The present invention provides an image generation apparatus, a radiographic imaging system, an image processing program, and an image processing method capable of generating a tomographic image in which a positional relationship between an object of interest to be collected and a collection needle can be appropriately confirmed. For the purpose.

  In order to achieve the above object, the image generating device according to claim 1 is designated by a designation unit for designating information related to a collection needle for collecting an object of interest from at least one of a living body and a non-living body, and the designation unit. Determination means for determining a slice interval based on the information related to the sampling needle, and the radiological image detector facing at least one of the living body and the non-living body from which the sampling needle collects the object of interest. Based on a plurality of radiation images acquired from the radiation image detector for each angle by irradiating the subject on the radiation image detector from a different angle from a radiation irradiation unit provided A tomographic image generating means for generating a tomographic image reconstructed at a slice interval determined by the determining means with reference to the detection surface of the radiation image detector , Comprising a.

  The designation unit causes the user to designate information related to the collection needle for collecting the object of interest from at least one of a living body and a non-biological body, and the determination unit determines the slice interval based on the information related to the collection needle designated by the designation unit. . The tomographic image generation device generates a tomographic image reconstructed at a slice interval determined by the determination unit.

  Depending on the sampling needle, various parameters such as the size of the opening for sampling the object of interest and the thickness of the sampling needle are different. For this reason, if the slice interval is inappropriate, the generated tomographic image does not cover the opening, and the positional relationship between the object of interest and the sampling needle may not be properly confirmed.

  On the other hand, in the present invention, since the slice interval is determined based on the information about the collection needle, it is possible to generate a tomographic image that can appropriately confirm the positional relationship between the object of interest to be collected and the collection needle.

  Further, according to the present invention, as in the image generation apparatus according to claim 2, the information about the collection needle is associated with a direction in which the collection needle is inserted into at least one of the living body and the non-living body. It can be at least one of the opening width of the needle opening and the diameter of the needle.

  Further, according to the present invention, as in the image generating apparatus according to claim 3, the determining unit determines the reduced slice interval as the slice interval decreases as the diameter of the sampling needle decreases. Can do.

  Further, according to the present invention, as in the image generating apparatus according to claim 4, the determining unit detects a region of interest including the object of interest, and designates a slice interval of the region of interest by the specifying unit. The slice interval other than the object region of interest can be determined to be larger than the slice interval of the object region of interest.

  The radiographic image capturing system according to claim 5 irradiates a subject on the radiographic image detector with radiation from a different angle from a radiation irradiation unit provided facing the radiographic image detector for each angle. The radiographic image detector that captures a plurality of radiographic images by the radiographic image detector, and a tomographic image is generated from the plurality of radiographic images captured by the radiographic image capturing device. Or an image generation device according to claim 1.

  The image generation program according to claim 6, wherein the computer causes the computer to designate information related to a collection needle for collecting an object of interest from at least one of a living body and a non-living body, and the collection needle designated by the designation means. And a radiation provided to face the radiological image detector with at least one of the living body and the non-living body from which the sampling needle collects the object of interest as a subject. Radiation detection of the subject based on a plurality of radiation images acquired from the radiation image detector for each angle by irradiating the subject on the radiation image detector from the irradiation unit from different angles. A tomographic image generating means for generating a tomographic image reconstructed at a slice interval determined by the determining means with reference to the detector detection surface; It is intended to function Te.

  The image generation method according to claim 7 includes a designation step for designating information on a collection needle for collecting an object of interest from at least one of a living body and a non-living body, and information on the collection needle designated by the designation unit. A determination step for determining a slice interval, and a radiation irradiation unit provided opposite to a radiation image detector with at least one of the living body and the non-living body from which the sampling needle collects the object of interest as a subject. The radiation image detector of the subject is detected based on a plurality of radiation images obtained by irradiating the subject on the radiation image detector from different angles and acquired from the radiation image detector at each angle. A tomographic image generation step of generating a tomographic image reconstructed at a slice interval determined in the determination step with respect to a plane.

  As described above, according to the present invention, it is possible to generate a tomographic image that can appropriately confirm the positional relationship between the object of interest to be collected and the collection needle.

It is a top view which shows an example of a structure of the radiographic imaging apparatus of this Embodiment. It is a figure which shows an example of the structure at the time of imaging | photography of the radiographic imaging apparatus of this Embodiment. It is explanatory drawing for demonstrating at the time of imaging | photography of the radiographic imaging apparatus of this Embodiment. It is a block diagram which shows an example of a structure of the radiographic imaging system of this Embodiment. It is explanatory drawing for demonstrating the information regarding the biopsy needle of this Embodiment. It is a flowchart which shows an example of the flow of the slice thickness determination process performed in the image generation apparatus of this Embodiment. Explanatory drawing for demonstrating a specific example of the correspondence of the kind (model name) of biopsy needle previously stored in the memory | storage part of the image generation apparatus of this Embodiment, and each parameter (A, B, C). It is. It is explanatory drawing for demonstrating the insertion direction of the biopsy needle of this Embodiment.

  Hereinafter, embodiments of the present invention will be described in detail with reference to the drawings. Note that this embodiment does not limit the present invention.

  As shown in FIGS. 1 to 3, the radiographic image capturing apparatus 10 of the present embodiment captures the breast N of the subject W with radiation (for example, X-rays) in the standing state where the subject W stands. An apparatus, for example, called mammography. In the following, when the subject W faces the radiographic image capturing apparatus 10 at the time of imaging, the near side near the subject W is defined as the front side of the radiographic image capturing apparatus 10, and the subject W faces the radiographic image capturing apparatus 10. The far side away from the subject W in this case is the rear side of the radiographic imaging device 10, and the left-right direction of the subject W when the subject W faces the radiographic imaging device 10 is the left-right direction of the radiographic imaging device 10. (See each arrow in FIGS. 1 to 3).

  Moreover, the imaging target of the radiographic image capturing apparatus 10 is not limited to the breast N, and may be, for example, another part of the body or an object. Further, as the radiographic imaging device 10, the breast W of the subject W in the sitting position where the subject W is sitting on a chair (including a wheelchair) or the lying position where the subject W is lying on the examination table or the like. There is no particular limitation as long as the breast N of the subject W can be separately photographed.

  As shown in FIG. 1, the radiographic image capturing apparatus 10 includes a measurement unit 12 having a substantially C-shaped side view provided on the front side of the apparatus, and a base unit 14 that supports the measurement unit 12 from the rear side of the apparatus. ing.

  The measuring unit 12 presses the breast N between the imaging surface 22 on which the planar imaging surface 20 that contacts the breast N of the subject W in the standing state is formed and the imaging surface 20 of the imaging table 22. , And a holding unit 28 that supports the imaging table 22 and the compression plate 26.

  The compression plate 26 is provided with a biopsy hand unit 38 for collecting necessary tissue from the biopsy site of the breast N. The compression plate 26 is provided with a rectangular opening 34 for tissue collection using the biopsy hand unit 38. The biopsy hand unit 38 includes a post unit 36 supported by the imaging table 22 and an arm unit 37 having one end connected to the post unit 36. A biopsy needle (collecting needle for collecting an object of interest) 40 is attached to the other end of the arm portion 37. An opening (not shown) for aspirating and collecting the tissue at the biopsy site of the breast N is provided at the distal end of the biopsy needle 40. The biopsy needle 40 is inserted in the direction along the surface of the compression plate 26 (direction parallel to the compression plate 26, the xy axis direction in FIG. 1) and the breast N by the biopsy hand unit 38 (the compression plate 26). Can be moved in the direction intersecting (FIG. 1, z-axis direction). In the present embodiment, the biopsy needle 40 is moved by the biopsy hand unit 38, so that the biopsy needle 40 passes through the opening 34 of the compression plate 26 toward the imaging surface 20 from the z-axis. It is configured to be inserted in a direction (insertion direction V, details will be described later), and the biopsy needle is inserted between the compression plate 26 and the imaging surface 20 in a direction parallel to the compression plate 26 (insertion direction L, It is configured such that it can be inserted into a later-described detail. Note that a member that transmits radiation is used for the compression plate 26.

  The measurement unit 12 is provided with a radiation source 30 such as a tube (see FIG. 4), a radiation irradiation unit 24 that irradiates radiation for inspection from the radiation source 30 toward the imaging surface 20, and a holding unit 28. Is provided with a support part 29 that is separated and supports the radiation irradiation part 24.

  The measuring unit 12 is provided with a rotating shaft 16 that is rotatably supported by the base unit 14. The rotation shaft 16 is fixed with respect to the support portion 29, and the rotation shaft 16 and the support portion 29 rotate together.

  The holding portion 28 can be switched between a state in which the rotation shaft 16 is connected and rotates integrally, and a state in which the rotation shaft 16 is separated and idles. Specifically, gears are provided on the rotating shaft 16 and the holding portion 28, respectively, and the meshing state and the non-meshing state of the gears are switched.

  Note that various mechanical elements can be used for switching between transmission and non-transmission of the rotational force of the rotating shaft 16.

  The holding unit 28 supports the imaging table 22 and the radiation irradiation unit 24 so that the imaging surface 20 and the radiation irradiation unit 24 are separated from each other by a predetermined distance, and the interval between the compression plate 26 and the imaging surface 20 is variable. The compression plate 26 is slidably held.

  The imaging surface 20 with which the breast N abuts is made of carbon, for example, from the viewpoint of radiolucency and strength. A radiation detector 32 that detects the radiation irradiated with the radiation that has passed through the breast N and the imaging surface 20 is disposed inside the imaging table 22. The radiation detected by the radiation detector 32 is visualized and a radiation image is generated.

  The radiographic image capturing apparatus 10 of the present embodiment is an apparatus that can perform imaging from a plurality of directions at least on the breast N as a subject. 2 and 3 respectively show the posture of the radiation image capturing apparatus 10 at the time of imaging and the position of the radiation irradiation unit 24 at the time of imaging. As shown in FIGS. 2 and 3, the imaging is performed by supporting the radiation irradiating unit 24 and inclining the support unit 29 that supports the imaging table 22 via the holding unit 28.

  As shown in FIG. 3, in the radiation imaging apparatus 10, when imaging (tomosynthesis imaging) is performed on the breast N from a plurality of directions, the rotation shaft 16 idles with respect to the holding unit 28 and presses against the imaging table 22. When the plate 26 does not move and the support portion 29 rotates, only the radiation irradiation portion 24 moves in an arc shape. In the present embodiment, as shown in FIG. 3, the imaging position is moved from the angle α by a predetermined angle θ, and imaging is performed at N positions where the radiation irradiation unit 24 is located at P1 to PN.

  In the radiographic image capturing apparatus 10 of the present embodiment, both CC (Cranio & Caudal: head-to-tail direction) imaging and MLO (Mediolital-Oblique: internal and external oblique direction) imaging are performed on the breast N. It is a device that can During CC imaging, the posture of the holding unit 28 is adjusted so that the imaging surface 20 faces upward, and the radiation irradiation unit 24 is positioned above the imaging surface 20 so that the radiation unit 24 is positioned upward. The posture is adjusted. Thereby, radiation is irradiated from the radiation irradiation unit 24 to the breast N from the head side to the foot side of the standing subject W, and CC imaging is performed. In MLO imaging, generally, the posture of the holding unit 28 is adjusted in a state where the imaging table 22 is rotated 45 ° or more and less than 90 ° compared to CC imaging, and the side wall angle of the imaging table 22 on the front side of the apparatus is adjusted. Positioning is performed so that the axilla of the subject W is applied to the part 22A. Thereby, the radiation is irradiated from the radiation irradiation unit 24 to the breast N from the axial center side of the body of the subject W to the outside, and MLO imaging is performed.

  A chest wall surface 25 is formed on the surface of the imaging table 22 on the front side of the apparatus so that the chest portion below the breast N of the subject W abuts at the time of imaging. The chest wall surface 25 is flat.

  In FIG. 4, the block diagram of an example of a structure of the radiographic imaging system 5 of this Embodiment is shown.

  The radiographic image capturing system 5 of the present embodiment includes a radiographic image capturing device 10, an image generating device 50, and a display device 80.

  The radiographic imaging device 10 includes a radiation irradiation unit 24, a radiation detector 32, an imaging device control unit 42, a biopsy unit 44, an operation panel 46, and a communication I / F unit 48.

  The imaging apparatus control unit 42 has a function of controlling the operation of the entire radiographic imaging apparatus 10, and includes a memory including a CPU (Central Processing Unit) 60, a ROM (Read Only Memory), and a RAM (Random Access Memory), A non-volatile storage unit such as an HDD (Hard Disk Drive) or a flash memory is provided. The imaging device control unit 42 is connected to the radiation irradiation unit 24, the radiation detector 32, the biopsy unit 44, the operation panel 46, and the communication I / F unit 48.

  When receiving an irradiation instruction from the operator through the operation panel 46 (exposure switch), the imaging apparatus control unit 42 is provided in the radiation irradiation unit 24 according to an imaging menu (described in detail later) set based on the specified exposure condition. Radiation is applied to the imaging surface 20 from the received radiation source 30.

  The radiation detector 32 records image information upon receiving irradiation of radiation carrying image information, and outputs the recorded image information. For example, a radiation sensitive layer is arranged to convert radiation into digital data. And output as an FPD (Flat Panel Detector). When radiation is irradiated, the radiation detector 32 outputs image information indicating a radiation image to the imaging device control unit 42. In the present embodiment, the radiation detector 32 receives radiation irradiated through the breast N and obtains image information indicating a radiation image.

  The operation panel 46 has a function for setting various operation information such as exposure conditions and posture information, various operation instructions, and the like.

  The exposure conditions set on the operation panel 46 include information such as tube voltage, tube current, irradiation time, and posture information. The posture information specified on the operation panel 46 includes information representing the photographing position (photographing posture and angle) when photographing the breast N from a plurality of directions.

  It should be noted that these operation conditions, various operation information such as posture information, various operation instructions, and the like may be set by the operator through the operation panel 46, or other control devices (RIS: Radiology Information System, It may be obtained from a radiation information system, a system that manages information such as medical treatment and diagnosis using radiation), or may be stored in advance in a storage unit.

  When various types of information are set from the operation panel 46, the imaging apparatus control unit 42 emits radiation from the radiation irradiation unit 24 according to the imaging menu set based on the set various types of information (breast N). Radiation images are taken by irradiation. When imaging from a plurality of directions, the imaging device control unit 42 adjusts the posture of the holding unit 28 so that the imaging surface 20 faces upward, and the radiation irradiating unit 24 moves upward with respect to the imaging surface 20. The attitude of the support portion 29 is adjusted to the position. Then, as shown in FIG. 3, the imaging device control unit 42 rotates the support unit 29 to move the radiation irradiation unit 24 in an arc shape from the angle α to the angle θ, and based on the imaging conditions, the radiation irradiation unit 24. The radiation X is individually irradiated at a different angle with respect to the imaging surface 20 from the radiation source 30 provided in FIG. Thereby, N radiation images are obtained.

  The biopsy unit 44 includes a biopsy hand unit 38 and a biopsy needle drive control unit 45. The biopsy needle drive control unit 45 drives the biopsy unit 44 in accordance with an instruction from the imaging device control unit 42 to hold the biopsy needle 40 in a state where it is moved to a predetermined position.

  The communication I / F unit 48 is a communication interface having a function for transmitting and receiving a radiographic image and various information captured between the radiographic image capturing apparatus 10 and the image generating apparatus 50 via the network 49. .

  The image generation device 50 has a function of generating a reconstructed tomographic image from the radiographic image acquired from the radiographic image capturing device 10.

  The image generation apparatus 50 includes a CPU 52, ROM 54, RAM 56, HDD 58, communication I / F unit 60, image display instruction unit 62, instruction reception unit 64, tomographic image generation unit 66, slice interval determination unit 68, and storage unit 72. Configured. These are connected to each other through a bus 75 such as a control bus or a data bus so that information can be exchanged.

  The CPU 52 controls the entire image generation apparatus 50 and the like, and specifically controls by executing a program 55 stored in the ROM 54. In the present embodiment, the program 55 is stored in advance. However, the present invention is not limited to this. The program 55 is stored in a recording medium such as a CD-ROM or a removable disk, and the ROM 54 or the like is recorded from the recording medium. It may be installed on the ROM 54 or the like from an external device via a communication line such as the Internet. The RAM 56 secures a work area when the CPU 52 executes the program 55. The HDD 58 stores and holds various data.

  The communication I / F unit 60 is a communication interface having a function for transmitting and receiving a radiographic image and various information captured between the image generation apparatus 50 and the radiographic image capturing apparatus 10 via the network 49. .

  The image display instruction unit 62 has a function of instructing the display 82 of the display device 80 to display a radiation image (tomographic image) or the like.

  The display device 80 according to the present embodiment has a function of displaying a captured radiographic image (tomographic image), and includes a display 82 on which a radiographic image is displayed and an instruction input unit 84. . In addition, the instruction input unit 84 has a function for a user (for example, a doctor) who wants to collect an object of interest such as calcification or a tumor to input an instruction related to display of a radiation image. , Keyboard, mouse and the like. In this embodiment, a person who collects or diagnoses an object of interest such as a tumor by a radiographic image taken by a doctor or the like is called a user, and a tissue to be collected for biopsy such as calcification or tumor is defined as a user. It is called a matter of interest.

  The instruction receiving unit 64 has a function of receiving an instruction from the user input by the instruction input unit 84 of the display device 80.

  The tomographic image generation unit 66 has a function of reconstructing a tomographic image from a plurality of radiation images obtained by tomosynthesis imaging and generating a tomographic image parallel to the imaging surface 20. In this embodiment, “parallel” is used, but it also includes substantially parallel.

  The tomographic image generation unit 66 generates a tomographic image from a plurality of radiation images I photographed at the positions P1, P2, P3,. The position at which the object of interest is projected on the radiation image differs depending on the imaging angle at which the radiation source 30 emits radiation from each position. Therefore, the tomographic image generation unit 66 acquires imaging conditions when the radiographic image is captured from the radiographic image capturing apparatus 10, and based on the imaging angle included in the imaging conditions, the object of interest between the plurality of radiographic images is acquired. The movement amount is calculated, and a tomographic image is reconstructed based on a known reconstruction method.

  The slice interval determination unit 68 has a function of determining a slice interval according to the type of the biopsy needle 40 based on information on the biopsy needle 40 specified by the user.

  The storage unit 72 stores various information in advance, and includes a so-called large-capacity hard disk. In the present embodiment, the correspondence between the model name of the biopsy needle 40 and each parameter and the correspondence between the insertion direction of the biopsy needle 40 and the parameter (both will be described in detail later) are stored in advance.

  Next, the operation of the radiation image capturing system 5 of the present embodiment will be described with reference to the drawings.

  In the radiographic image capturing system 5 of the present embodiment, when performing a biopsy, the ray image capturing device 10 performs tomosynthesis imaging to acquire an image. A slice thickness for reconstructing a tomographic image is determined in advance by the image generation device 50 based on information about the biopsy needle 40 used for biopsy. The acquired image is reconstructed with the determined slice pressure. The position of the target is detected from the reconstructed image. Then, after inserting the biopsy needle 40 into the breast N, the radiographic imaging device 10 performs stereo imaging and displays it on the display device 80 to allow the user to confirm the positional relationship between the target to be acquired and the biopsy needle.

  In the present embodiment, as information related to the biopsy needle 40, the position of the opening for collecting the target (FIG. 5, A: biopsy needle opening position, reference, hereinafter referred to as parameter A), the width of the opening. (FIG. 5, B: biopsy needle opening width, reference, hereinafter referred to as parameter B) and diameter (FIG. 5, C: biopsy needle diameter, reference, hereinafter referred to as parameter C) are used.

  First, radiographic image capturing in the radiographic image capturing apparatus 10 of the present exemplary embodiment will be described. When radiographing is performed, the radiographic imaging device 10 executes imaging according to the imaging menu when the imaging menu is set.

  When the radiographing apparatus 10 receives radiographing instructions for radiographing the breast N from a plurality of directions, the posture of the holding unit 28 is adjusted so that the radiographing surface 20 faces upward as shown in FIG. At the same time, the posture of the support unit 29 is adjusted so that the radiation irradiation unit 24 is positioned above the imaging surface 20.

  The subject W brings the breast N into contact with the imaging surface 20 of the radiographic imaging device 10. In this state, the radiographic imaging device 10 moves the compression plate 26 toward the imaging surface 20 when the operator gives an operation instruction for starting compression to the operation panel 46.

  In this state, the radiation imaging apparatus 10 according to the present embodiment rotates the support unit 29 only when the imaging instruction for imaging the breast N from a plurality of directions is input to the operation panel 46. The part 24 is moved in an arc shape, and as shown in FIG. 3, the photographing position is moved from the angle α by a predetermined angle θ, and the radiation irradiating part 24 is located at N positions P1 to PN based on the photographing conditions. Irradiate with radiation. The radiation individually irradiated from the radiation irradiation unit 24 reaches the radiation detector 32 after passing through the breast N.

  When the radiation is irradiated, the radiation detector 32 outputs image information indicating the irradiated radiation image to the imaging device control unit 42, respectively. As described above, when radiation irradiation is performed at N positions P1 to PN of the radiation irradiation unit 24, image information of N radiation images is output to the imaging device control unit 42. .

  The imaging device control unit 42 outputs each input image information to the image processing device 50. Note that, as described above, when the radiation irradiation unit 24 is irradiated with radiation at the N positions P1 to PN, the CPU of the imaging device control unit 42 stores the image information of the N radiation images. The image is output to the image processing apparatus 50.

  The image processing apparatus 50 performs tomographic image generation processing for reconstructing a tomographic image from the N radiation images input from the radiographic image capturing apparatus 10 and displaying the reconstructed tomographic image on the display device 80.

  Next, the slice thickness determination process performed in advance will be described in detail. FIG. 6 shows a flowchart of an example of the flow of slice thickness determination processing executed in the image processing apparatus 50 according to the present embodiment. This process is executed when the control program 55 stored in the ROM 54 is processed by the CPU.

  In step 100, designation of the type of biopsy needle 40 is accepted. In the present embodiment, as a specific example, a list of types (model names) of biopsy needles 40 registered in advance in the storage unit 72 is displayed on the display 82 of the display device 80. Based on the display, the user selects the type of biopsy needle 40 to be used and gives an instruction using the instruction input unit 84. In the present embodiment, the correspondence between the biopsy needle type (model name) and each parameter (A, B, C) is stored in advance. An example of the correspondence relationship is shown in FIG.

  In the next step 102, designation of the insertion direction of the biopsy needle 40 is accepted. In the present embodiment, the insertion direction specified by the instruction input unit 84 is received from the user. In the present embodiment, as shown in FIG. 8, the direction in which the biopsy needle 40 is inserted from the direction intersecting the imaging surface 20 is referred to as the insertion direction V, and the direction in which the biopsy needle 40 is inserted from the direction intersecting the imaging surface 20. Is referred to as the insertion direction L. In the present embodiment, an instruction indicating whether the insertion direction is the insertion direction V or L is instructed by the instruction input unit 84. In the present embodiment, the correspondence between the insertion direction and the parameters (A, B, C) used for determining the slice thickness is stored in advance in the storage unit 72. In the present embodiment, when the insertion direction is the insertion direction V, at least the parameter B is associated, and when the insertion direction is the insertion direction L, at least the parameter C is associated. The parameter A does not directly contribute to the determination of the slice thickness, but is used for alignment between the three-dimensional position of the region of interest and the opening position of the biopsy needle 40. Therefore, in this embodiment, the parameter B and the parameter A are used. In association with C.

  In the next step 104, parameters according to the type of the biopsy needle 40 specified in step 100 and the insertion direction of the biopsy needle 40 specified in step 102 are acquired. In the present embodiment, the correspondence (see FIG. 7) between the biopsy needle type (model name) and each parameter (A, B, C), the insertion direction, and the slice, which are stored in the storage unit 72 described above. The parameters are acquired with reference to the correspondence relationship with the parameters (A, B, C) used for determining the thickness.

  In the next step 106, the position (three-dimensional coordinates) of the target is acquired. Although the method for acquiring the target position is not particularly limited, in the present embodiment, a radiographic image of the breast N of the subject W such as a tomographic image generated by the image generation device 50 is displayed on the display 82 of the display device 80, and The target position (three-dimensional coordinates) is detected based on the target position designated by the user by display.

  In the next step 108, the slice thickness is determined based on the parameter acquired in step 104 and the target position acquired in step 110, and then the present process is terminated. In the present embodiment, when the insertion direction is the insertion direction V, the slice thickness is determined so that the parameter B is equally divided with the target position as the center. When the insertion direction is the insertion direction L, the slice thickness is determined so that the parameter C is equally divided around the target position. Note that when generating tomographic images of all regions including the region not including the target, from the viewpoint of confirming the positional relationship between the target and the biopsy needle, only the region including the target is set to the slice thickness, and the target is A region not included may have a larger slice thickness. By doing in this way, the number of tomographic images generated can be reduced.

  As described above, in the radiographic imaging system 5 of the present embodiment, when the type of the biopsy needle 40 and the insertion direction of the biopsy needle 40 are designated, the type of the biopsy needle 40 and the insertion direction of the biopsy needle 40 are determined. As information of the biopsy needle 40 according to the above, parameter A (biopsy needle opening position), parameter B (biopsy needle opening width), and parameter C (biopsy needle diameter) associated in advance are acquired. Further, the target position is acquired, and the slice interval determination unit 68 determines the slice interval based on the target position (three-dimensional coordinates) and parameters. A radiographic image of the subject W is captured by the radiographic image capturing device 10, and a tomographic image is generated from a plurality of captured radiographic images at a determined slice interval, and the display of the display device 80 82 is displayed.

  Thus, since tomographic images are generated at slice intervals according to the type and insertion direction of the biopsy needle 40, a tomographic image that can appropriately confirm the positional relationship between the target and the biopsy needle can be generated. Moreover, since it can set for every kind of biopsy needle 40, position confirmation can be performed easily.

  In this embodiment, the position of the target is acquired, and the slice thickness is determined with the target position as the center. However, the present invention is not limited to this, and when generating tomographic images of the entire region, Based on only the parameters without acquiring the position, for example, if the insertion direction is V, it is determined to be equally divided at an interval smaller than parameter B, and if the insertion direction is L, it is equally divided at an interval smaller than parameter C. You may decide so. Further, the thickness is not limited to equal division, and the thickness may be changed. In addition, it is preferable to make slice thickness small, so that the diameter (parameter C) of the biopsy needle 40 becomes small.

  In the present embodiment, the correspondence relationship between the biopsy needle type (model name) and each parameter (A, B, C) is stored in advance. You may make it input a parameter. The parameters to be used are not limited to the present embodiment, and parameters to be used may be determined according to the insertion direction of the biopsy needle 40, the biopsy method, and the like.

  In addition, when using a plurality of types of biopsy needles 40, the slice thickness may be determined for each type of biopsy needle 40, and a tomographic image may be generated for each type of biopsy needle 40.

  In this embodiment, the slice thickness is determined in advance. However, the present invention is not limited to this. For example, the slice thickness may be determined after the biopsy needle 40 is inserted into the breast N. It is preferable to determine in advance because the processing time for generating a tomographic image is shortened, and therefore the time during which the biopsy needle 40 is inserted into the breast N can be shortened.

  In the present embodiment, the case where the present invention is applied to generation of a tomographic image of a radiographic image captured by mammography has been described, but the present invention is not limited to this, and is captured by another radiographic image capturing device. The present invention may be applied to generation of a tomographic image of a radiographic image. In the present embodiment, the case where the present invention is applied to the generation of a tomographic image of a radiographic image obtained by photographing a human body as a living body has been described. You may apply to the production | generation of the tomographic image of the radiographic image by which the biological body (for example, the phantom imitating a human body etc.) etc. was image | photographed.

  Moreover, the radiation used for radiographic imaging is not particularly limited, and X-rays, γ-rays, and the like can be applied.

  In addition, the configurations of the radiographic image capturing system 5, the radiographic image capturing device 10, the image generating device 50, and the display device 80 described in the present embodiment are merely examples, and can be used according to the situation without departing from the gist of the present invention. Needless to say, it can be changed.

  Further, the flow of slice thickness determination processing described in the present embodiment is also an example, and it goes without saying that it can be changed according to the situation without departing from the gist of the present invention.

DESCRIPTION OF SYMBOLS 5 Radiographic imaging system 10 Radiographic imaging apparatus 50 Image generation apparatus 66 Tomographic image generation part 68 Slice space | interval determination part 80 Display apparatus N Breast W Subject

Claims (7)

Designating means for designating information related to a collection needle for collecting an object of interest from at least one of a living body and a non-living body;
Determining means for determining a slice interval based on information on the sampling needle designated by the designation means;
The at least one of the living body and the non-living body from which the sampling needle collects the object of interest is used as a subject, and a radiation irradiation unit provided facing the radiation image detector is applied to the subject on the radiation image detector. Slicing intervals determined by the determining means based on a plurality of radiographic images acquired from the radiographic image detector by irradiating radiation from different angles and obtained from the radiographic image detector for each angle. A tomographic image generating means for generating a tomographic image reconstructed in
An image generation apparatus comprising:   The information about the collection needle is at least one of the opening width of the opening of the collection needle associated with the direction in which the collection needle is inserted into at least one of the living body and the non-living body, and the diameter of the needle. The image generation apparatus according to claim 1.   The image generation apparatus according to claim 1, wherein the determination unit determines a reduced slice interval as the diameter of the sampling needle as the slice interval.   The determining unit detects a region of interest including the object of interest, determines a slice interval of the region of interest based on information on the sampling needle specified by the specifying unit, and other than the region of interest The image generation apparatus according to any one of claims 1 to 3, wherein the slice interval is determined to be an interval larger than a slice interval of the region of interest. Radiation is applied to the subject on the radiographic image detector from a different angle from a radiation irradiation unit provided facing the radiographic image detector, and a plurality of radiographic images are obtained by the radiographic image detector at each angle. A radiographic imaging device for imaging;
The image generation apparatus according to any one of claims 1 to 4, wherein a tomographic image is generated from a plurality of radiographic images captured by the radiographic image capturing apparatus.
Radiographic imaging system equipped with. Computer
Designating means for designating information related to a collection needle for collecting an object of interest from at least one of a living body and a non-living body;
Determining means for determining a slice interval based on information on the sampling needle designated by the designation means;
The at least one of the living body and the non-living body from which the sampling needle collects the object of interest is used as a subject, and a radiation irradiation unit provided facing the radiation image detector is applied to the subject on the radiation image detector. Slicing intervals determined by the determining means based on a plurality of radiographic images acquired from the radiographic image detector by irradiating radiation from different angles and obtained from the radiographic image detector for each angle. A tomographic image generating means for generating a tomographic image reconstructed in
An image generation program to make it function. A designation step for designating information on a collection needle for collecting an object of interest from at least one of a living body and a non-living body;
A determination step of determining a slice interval based on information on the sampling needle specified by the specifying means;
The at least one of the living body and the non-living body from which the sampling needle collects the object of interest is used as a subject, and a radiation irradiation unit provided facing the radiation image detector is applied to the subject on the radiation image detector. Slicing intervals determined in the determination step based on a plurality of radiographic images acquired from the radiographic image detector at different angles by irradiating radiation from different angles with reference to the detection surface of the radiographic image detector of the subject A tomographic image generation process for generating a tomographic image reconstructed in
An image generation method comprising:

Images