JP2010057990A - Magnetic resonance diagnosing device - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To shorten imaging time to the minimum while securing necessary image contrast in a magnetic resonance diagnosing device using prepulses such as fat restricting pulses. <P>SOLUTION: The magnetic resonance imaging device applies flip pulses repeatedly, receives one or a plurality of MR signals phase-encoded and slice-encoded according to a 3DFT imaging method after the flip pulses are respectively applied, and generates images based on the received MR signals. The magnetic resonance imaging device generates the prepulses so that prepulse application frequency to the flip pulses is lowered from the zero-encoded center for phase encoding and slice encoding toward the outer side in three-dimensional space K. <P>COPYRIGHT: (C)2010,JPO&INPIT

Description

  The present invention relates to a magnetic resonance diagnostic apparatus, and more particularly to an improvement in a method for applying a pre-pulse such as a fat suppression pulse applied before applying a flip pulse (high-frequency excitation pulse).

  A typical fat suppression pulse as a pre-pulse is a flip pulse narrowed according to the chemical shift between fat and water, which selectively excites only fat and then fully dephases it by applying a gradient magnetic field, Thereby, the magnetic resonance signal (MR signal) from fat is reduced. Recently, fat suppression pulses are indispensable for improving the image quality, particularly in MR angiography (MRA).

  As is well known, the principle of MRA is that a stationary object such as a brain parenchyma or an organ in an imaging region is excited one after another while its longitudinal magnetization has not recovered much, so the signal level gradually decreases. Since blood (water) always flows into the imaging region in a fresh state, the signal is not lowered as much as a stationary object. For this reason, an image (blood flow image) in which blood flow is relatively emphasized as compared with a stationary object is obtained. In such MRA, fat suppression is applied by applying a fat suppression pulse as a pre-pulse immediately before the application of the flip pulse in order to improve image quality.

  As described above, in order to narrow the fat suppression pulse, it is necessary to extend the pulse width of the fat suppression pulse from ± π length to ± 4 · π length, for example. For this reason, the imaging time required to collect all the data necessary for image generation is prolonged, and imaging cannot be completed within one breath holding time, which increases the burden on the patient, and causes body motion artifacts. Various clinical inconveniences such as increased chances of occurrence occur.

  An object of the present invention is to shorten the imaging time as much as possible while ensuring a necessary image contrast in a magnetic resonance diagnostic apparatus using a pre-pulse such as a fat saturation pulse.

  According to one aspect of the present invention, one or a plurality of MR signals subjected to phase encoding and slice encoding are received according to a 3DFT imaging method after applying a flip pulse repeatedly, and based on the received MR signal. In the magnetic resonance imaging apparatus for generating an image, the pre-pulse is applied so that the frequency of application of the pre-pulse to the flip pulse decreases outward from the center of zero encoding of the phase encoding and slice encoding on a three-dimensional K space. It is generated.

  According to the present invention, in a magnetic resonance diagnostic apparatus using a pre-pulse such as a fat suppression pulse, the imaging time can be shortened while ensuring the necessary image contrast at a minimum.

FIG. 1 is a diagram showing a configuration of a magnetic resonance imaging apparatus according to an embodiment of the present invention. FIG. 2 is a diagram showing an example of a pulse sequence when a pre-pulse is applied at a frequency of one flip pulse in the present embodiment. FIG. 3 is a diagram showing an example of a pulse sequence in the case where a pre-pulse is applied at a frequency of once for two flip pulses in the present embodiment. FIG. 4 is a diagram showing an example of a pulse sequence when a pre-pulse is applied at a frequency of once for three flip pulses in the present embodiment. FIG. 5 is a diagram showing a change in the prepulse application frequency in the K space of the 3DFT method in the present embodiment. FIG. 6 is a diagram showing a change in prepulse application frequency in the K-space of the 2DFT method in the present embodiment.

Hereinafter, a magnetic resonance imaging apparatus according to the present invention will be described in detail with reference to the drawings.
FIG. 1 is a diagram showing a configuration of a magnetic resonance imaging apparatus according to an embodiment of the present invention. For example, inside the cylindrical static magnetic field magnet 1, a shim coil 3 that generates a magnetic field for receiving a power supply from a shim coil power supply 6 under the control of the computer system 12 to improve the static magnetic field uniformity, and three orthogonal axes. A gradient coil 2 that individually generates a gradient magnetic field pulse and a probe (RF coil) 4 that applies a high-frequency magnetic field pulse (RF pulse) to the subject and receives an MR signal from the subject are provided. Note that the probe 4 may be provided separately for transmission and reception without being used for transmission and reception.

  The sequence control unit 10 includes a gradient coil power source 5 that applies a gradient magnetic field pulse to the subject via the gradient coil 2, a transmitter 7 that applies a high frequency magnetic field pulse to the subject via the probe 4, and the subject via the probe 4. The receiver 9 that receives MR signals from the specimen and the data collection unit 11 that collects MR signals received via the receiver 9 are controlled according to a predetermined pulse sequence. In addition to the function as a host computer of the entire apparatus, the computer system 12 uses the 2DFT (2D Fourier transform) method or the 3DFT (3D Fourier transform) method based on the MR signals collected by the data collection unit 11. It has a calculation function to generate. The display 14 is provided to display MR images generated by the computer system 12 and various information.

  The pulse sequence executed by the control of the above-described sequence control unit 10 is set to a specific pulse sequence in the spin echo (SE) method, the field echo (FE) method, the echo planer (EPI) method, or the like, or Of these, an operator can arbitrarily select the information via the console 13. In addition, a pre-pulse such as a fat suppression pulse can be inserted into this pulse sequence, and the sequence controller 10 can control the pre-pulse application method. This pre-pulse application method is characteristic in the present invention, and will be described in detail below. Examples of pre-pulses other than fat suppression pulses include pre-saturation pulses, tagging, and MTC.

  In FIG. 2, when the spin warp method is employed as the MR signal generation technique and the 3DFT method is employed as the imaging technique, a pre-pulse is applied at a frequency of once every time a flip pulse (high frequency excitation pulse) is applied. The pulse sequence is shown. As is well known, in the 3DFT method, out of three gradient magnetic field pulses with different gradient axes generated by the gradient coil 3, the gradient magnetic field (RO) of a certain axis is used to frequency encode the MR signal, The axial gradient field (SLICE) is used to slice select and slice encode the MR signal, and the remaining axial gradient field (PE) is used to phase encode the MR signal. In the two-dimensional Fourier transform method (2DFT method), unlike the 3DFT method, the gradient magnetic field (SLICE) is not used for slice encoding but is used only for slice selection.

  In this 3DFT method, the flip pulse is repeatedly applied at a cycle of the repetition time TR while changing the slice encoding and phase encoding patterns little by little. In the case of FIG. 2, a pre-pulse is applied once for each flip pulse. They are applied one by one.

  FIG. 3 shows a pulse sequence when a pre-pulse is applied at a frequency of once every time a flip pulse is applied twice. That is, in this case, a pre-pulse is applied to one of adjacent pairs of flip pulses, but no pre-pulse is applied to the other flip pulse.

  FIG. 4 shows a pulse sequence when a pre-pulse is applied at a frequency of once every time a flip pulse is applied three times. That is, in this case, a pre-pulse is applied to one of the three consecutive flip pulses, but no pre-pulse is applied to the remaining two flip pulses.

  FIG. 5 shows a change in prepulse application frequency in the K space in the 3DFT method. In a period in which MR signals in a predetermined region (center region) centering on zero encoding in the K space that most affects the image contrast are collected, a pre-pulse is performed at a frequency of once for each flip pulse shown in FIG. Apply. In a period in which MR signals in the region outside the central region (intermediate region) are collected, a pre-pulse is applied at a frequency of once for every two flip pulses shown in FIG. In the period in which MR signals in the region outside the intermediate region (outer region) are collected, a pre-pulse is applied at a frequency of once for three flip pulses shown in FIG. Then, no pre-pulse is applied to the flip pulse during a period in which MR signals in the outermost region having the least influence on the image contrast outside the outer region are collected. In contrast angiography, since the contrast immediately after the start of imaging is emphasized, application of prepulses and flip pulses is started after idle shooting.

  As described above, the frequency of applying the pre-pulse to the flip pulse gradually decreases from the zero encoding toward the outside in the K space, and the pre-pulse is not applied in the outermost region, so that the entire region of the K space is uniformly 1 The imaging time can be significantly shortened compared to the case where a pre-pulse is applied once for each flip pulse. Further, since the frequency of the pre-pulse is decreased from the central region having a large influence on the image contrast toward the outside, it is possible to suppress a significant decrease in the image contrast.

  Further, as shown in FIG. 6, the present invention can also be applied to the 2DFT method. That is, during the period in which the MR signal in the central region of the K space that most affects the image contrast is collected, the pre-pulse is applied at a frequency of once per flip pulse, and the MR signal in the intermediate region is collected. Applies a pre-pulse at a frequency of once per two flip pulses, applies a pre-pulse at a frequency of once per three flip pulses during the period of collecting MR signals in the outer region, and the outermost No pre-pulse is applied to the flip pulse during the period in which the MR signal of the region is collected. As described above, even in the 2DFT method, the frequency of applying the prepulse to the flip pulse gradually decreases from the zero encoding to the outside in the K space, and the prepulse is not applied in the outermost region, so that the same as in the case of the 3DFT method. There is an effect.

  The present invention is not limited to the embodiment described above, and can be implemented with various modifications. For example, in the above description, the frequency of the pre-pulse with respect to the flip pulse is reduced from once to once, once every two times, and once every three times. However, the frequency may be decreased step by step, such as once at once, once every three times, once every five times, or may be changed in various other patterns. It is also possible to arbitrarily adjust the image contrast by arbitrarily setting the correspondence between the area in the K space and the frequency.

  INDUSTRIAL APPLICABILITY The present invention can be used in a field in which it is required to shorten the imaging time as much as possible while securing a necessary image contrast in a magnetic resonance diagnostic apparatus using a pre-pulse such as a fat saturation pulse.

  DESCRIPTION OF SYMBOLS 1 ... Static magnetic field magnet, 2 ... Gradient coil, 3 ... Shim coil, 4 ... Probe, 5 ... Gradient coil power supply, 6 ... Shim coil power supply, 7 ... Transmitter, 9 ... Receiver, 0 ... Sequence control part, 11 ... Data collection Part, 12 ... computer system, 13 ... console, 14 ... image display.

Claims (5)

Magnetic resonance that repeatedly applies flip pulses, receives one or a plurality of MR signals that have been subjected to phase encoding and slice encoding according to the 3DFT imaging method after applying each flip pulse, and generates an image based on the received MR signals In video equipment,
A magnetic resonance imaging apparatus for generating a pre-pulse so that an application frequency of a pre-pulse to the flip pulse decreases outward from the center of zero encoding of the phase encoding and slice encoding on a three-dimensional K space. . In a magnetic resonance imaging apparatus that repeatedly applies a flip pulse, receives one or a plurality of MR signals encoded according to a 3DFT imaging method after applying each flip pulse, and generates an image based on the received MR signals.
2. The magnetic resonance imaging apparatus according to claim 1, wherein the prepulse is generated so that a prepulse application frequency with respect to the flip pulse varies with time. 2. The magnetic resonance imaging apparatus according to claim 1, wherein an interval between the flip pulses is narrower in an outermost region of the K space than in a central region near the zero encoding. 4. The magnetic resonance imaging apparatus according to claim 1, wherein the pre-pulse is a fat suppression pulse. 4. The magnetic resonance imaging apparatus according to claim 1, wherein the pre-pulse is a pre-saturation pulse or a tagging pulse.

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