JP2010035921A - Filling device for biological bone - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a filling device for a biological bone for fixing an artificial bone to a biological bone without generating cracking or the like in the artificial bone, while preventing a biological tissue from being damaged. <P>SOLUTION: The filling device 1 includes the artificial bone 10, a joining plate 20, and a fixing member 30. A first inserting hole 12 is formed in the artificial bone 10. A second inserting hole 26 and a third inserting hole are provided in the joining plate 20. The fixing member 30 comprises a pipe member 32 smaller in diameter than the first inserting hole 12, and a flange part 34a larger in diameter than the first inserting hole 12. The pipe member 32 is inserted from the inner surface side of the artificial bone 10 to the fist inserting hole 12. The flange part 34a is engaged with an inner surface side circumferential edge of the first inserting hole 12. The pipe member 32 is further inserted to the second inserting hole 26. A protruded part is cut and caulked, and the caulked part is engaged with a circumferential edge of the second inserting hole 26. One end of the joining plate 20 is thus joined with the artificial bone 10. <P>COPYRIGHT: (C)2010,JPO&INPIT

Description

  The present invention relates to a living bone repair device for, for example, filling a missing part when a defect occurs in a living bone such as a skull.

  For example, when a living bone is lost due to an accident or the like, an artificial bone may be supplemented to the defective portion instead of the living bone. In addition, when a craniotomy or the like is performed by excising a part of the skull for the treatment of a brain tumor, a cerebral thrombus, or the like, an artificial bone may be supplemented to the skull defect. As described above, a technique for filling a defect portion of a living bone with an artificial bone is widely used.

  The following Patent Document 1 discloses an artificial bone provided with a fixing member comprising a screw member screwed to an artificial bone and a living bone, and a bridging member that is fixed at both ends by the screw member and connects the artificial bone and the living bone. A fixing structure is disclosed. And after inserting the buffer member which has the cylindrical part and which has the expansion part divided | segmented into several into the opening part previously formed in the artificial bone, a screw member is screwed in a buffer member through the hole of a bridge | crosslinking member, and is tightened. As a result, the expanding portion expands and engages with the opening, and the bridging member is fixed to the artificial bone via the buffer member.

Patent Document 2 below discloses a skull valve clamp that includes a first clamping member and a second clamping member that form a circular umbrella-shaped flange, and a cylindrical extension member that connects the first and second clamping members. Yes. The extension member of the fastener is disposed between the butted portions of the skull and the bone flap, the first fastening member is disposed on the inner edge of the skull and the bone flap, and the second fastening member is disposed on the skull and the bone. A second tightening member is disposed at the outer surface side edge of the valve. After that, both ends of the extension member are crimped and the first and second tightening members are bent and deformed so that the skull and bone flap are sandwiched between the first and second tightening members. And are to be fixed.
JP 2006-230787 A JP-T-2004-504883

  In Cited Document 1, when the screw member is tightened in the buffer member, the expanded portion divided into a plurality of parts is expanded and engaged with the opening. At this time, the expanded expansion is performed. Since the inner periphery of the opening of the artificial bone is strongly pressed by the portion, there is a possibility that a crack or a crack is likely to occur from the periphery of the opening of the artificial bone.

  In addition, when the screw member is screwed in, the artificial bone is strongly pressed through the buffer member, and in this case, there is a possibility that the artificial bone is cracked.

  On the other hand, in Cited Document 2, when fixing the skull and bone flap, both the front and back surfaces are sandwiched between the first and second flange-shaped tightening members, so that the tightening member is located on the inner surface side of the skull. There is a risk of interference with the internal tissue of the skull.

  Furthermore, when the thicknesses of the skull and the bone flap are different, if they are sandwiched between the first and second fastening members, a gap is generated between each fastening member and the skull or bone flap, resulting in looseness. There arises a disadvantage that the valves cannot be firmly connected.

  Furthermore, since the first and second fastening members that sandwich the skull and bone flap have an umbrella-shaped flange shape, it is difficult to follow the shape of the skull with many bending surfaces and bend and deform appropriately. There is a demerit that the application part of is limited.

  Therefore, an object of the present invention is to provide an artificial bone to the living bone even if the living bone and the artificial bone have different thicknesses or have a bent shape. An object of the present invention is to provide a living bone prosthesis that can fix a body and prevent damage to living tissue and the like.

  In order to achieve the above object, a first aspect of the present invention is an artificial bone having a shape that compensates for a defect in a living bone, and a connecting plate having one end fixed to the artificial bone and the other end fixed to the living bone. A living bone prosthesis comprising a fixture for fixing one end of the connecting plate to the artificial bone, the artificial bone has a first insertion hole for fixing the connecting plate; The connection plate is provided with a second insertion hole for fixing to the artificial bone and a third insertion hole for fixing to the living bone, and the fixture includes the first insertion hole and A pipe member having an outer diameter smaller than the inner diameter of the second insertion hole, and a flange portion formed at one end thereof and having an outer diameter larger than the inner diameter of the first insertion hole, The pipe member of the fixture is inserted into the first insertion hole from the inner surface side. Then, the flange portion is engaged with the inner peripheral edge of the first insertion hole of the artificial bone, and the pipe member inserted from the first insertion hole is further inserted into the second insertion hole of the connection plate. Then, by cutting and caulking the portion inserted from the second insertion hole, the caulking portion is engaged with the periphery of the second insertion hole, and one end of the connecting plate and the artificial bone are connected. It is intended to provide a living bone prosthesis characterized by the above.

  According to the above invention, from the inner surface side of the artificial bone, the pipe member of the fixing tool is inserted into the first insertion hole, and the flange portion is engaged with the inner surface side periphery of the first insertion hole of the artificial bone. The pipe member inserted from the hole is further inserted into the second insertion hole of the connecting plate, and the portion inserted from the second insertion hole is cut and caulked, so that the caulking portion is placed around the periphery of the second insertion hole. By engaging, one end of the connection plate and the artificial bone can be connected. The outer diameter of the pipe member is smaller than the inner diameter of the first insertion hole, and the caulking portion is not strongly pressed and engaged with the periphery of the second insertion hole, so that an excessive tightening stress is applied to the artificial bone. This can reliably prevent the artificial bone from cracking or cracking.

  As described above, since the artificial bone and the connecting plate are connected in advance by the fixing tool, the doctor places the artificial bone on the defect portion of the living bone during surgery, and attaches the artificial bone to the artificial bone. By fixing the other end of the connected connecting plate to the living bone through the third insertion hole using a fixing means such as a screw, the artificial bone can be quickly attached to the living bone with a simple operation.

  Moreover, since the crimping part of a fixing tool is arrange | positioned on the outer surface side of an artificial bone, a crimping part does not locate in a living body bone, For example, it can prevent damaging internal tissues, such as a skull.

  Furthermore, since the artificial bone and the living bone are fixed via a connecting plate arranged on the front side, even if the thicknesses of the artificial bone and the living bone are different, both can be reliably fixed. .

  Furthermore, even when an artificial bone is fixed to a living bone having a large bending shape such as a skull, it is possible to flexibly adjust the bending shape of the living bone by appropriately bending the connecting plate for connecting the artificial bone and the living bone. Correspondingly, both the artificial bone and the living bone can be aligned and fixed.

  According to a second aspect of the present invention, in the first aspect of the present invention, there is provided a living bone prosthesis device in which a tapered concave portion that is recessed toward the inner surface side is formed at the outer peripheral edge of the second insertion hole of the connection plate. To do.

  According to the above invention, the caulking portion of the pipe member of the fixture enters the tapered concave portion and engages with the second insertion hole, so that it is difficult to protrude outward and covers the outside of the artificial bone. Can prevent tissue damage.

  According to a third aspect of the present invention, in the first or second aspect of the present invention, a deeper recess is formed on the inner peripheral edge of the first insertion hole of the artificial bone than the thickness of the flange portion of the fixture. The present invention provides a bone repair device.

  According to the above invention, when the flange portion of the fixture is engaged with the inner surface side periphery of the first insertion hole of the artificial bone, the flange portion is accommodated in the recess and does not protrude toward the inner surface side. In this case, damage to the inner brain tissue and the like can be prevented.

  According to the living bone prosthesis of the present invention, the pipe member is inserted into the first insertion hole from the inner surface side of the artificial bone, and this is inserted into the second insertion hole of the connection plate, and then the inserted portion is cut. In addition, by caulking, the one end of the connecting plate and the artificial bone can be connected by engaging the caulking portion with the peripheral edge of the second insertion hole. The outer diameter of the pipe member is smaller than the inner diameter of the first insertion hole, and the caulking portion is not strongly pressed and engaged with the periphery of the second insertion hole, so that an excessive tightening stress is applied to the artificial bone. This can reliably prevent the artificial bone from cracking or cracking.

  Moreover, since the crimping part of a fixing tool is arrange | positioned on the outer surface side of an artificial bone, a crimping part does not locate in a living body bone, For example, it can prevent damaging internal tissues, such as a skull. Furthermore, since the artificial bone and the living bone are fixed via a plate arranged on the front side, even if the thicknesses of the artificial bone and the living bone are different, both can be reliably fixed. Furthermore, even when an artificial bone is fixed to a living bone having a large bending shape such as a skull, it is possible to flexibly adjust the bending shape of the living bone by appropriately bending the connecting plate for connecting the artificial bone and the living bone. Correspondingly, both the artificial bone and the living bone can be aligned and fixed.

  Hereinafter, an embodiment of a living bone prosthesis according to the present invention will be described with reference to the drawings.

  For example, when performing a craniotomy for treatment of a brain tumor, a cerebral thrombus, etc., the scalp is incised, a plurality of bar holes 4 are opened, and a part of the living bone 3 which is a skull is excised using these as base points. An open defect 5 is formed (see FIG. 1). A living bone prosthetic device 1 (hereinafter referred to as “compensating device 1”) according to the present invention in this embodiment is used to compensate for the defect 5 formed in the living bone 3 such as the skull as described above. It is.

  As shown in FIG. 2, the filling device 1 includes an artificial bone 10 having a shape for filling a defect 5 of a living bone 3, one end fixed to the artificial bone 10, and the other end fixed to the living bone 3. And a fixing tool 30 for fixing one end of the connection plate 20 to the artificial bone 10.

  In this embodiment, an artificial bone 10 having a so-called bone flap shape corresponding to the shape of the defect portion 5 formed in the living bone 3 such as the skull is used as a supplement material. In fields such as orthopedics related to the organ system, it can be used to compensate for a defect in a living bone, and is not particularly limited.

  First, the artificial bone 10 will be described. The artificial bone 10 is made of a material mainly composed of calcium phosphate compounds such as hydroxyapatite, fluorapatite, tricalcium phosphate, ceramics such as alumina, zirconia, or a mixture of two or more of the above materials. The Among these, the main component of hydroxyapatite, which is the same component as the living bone 3, is preferable from the viewpoint of ensuring biocompatibility.

  The artificial bone 10 is formed in a shape suitable for the defect part 5 to be compensated for in the living bone 3. As a method for forming the artificial bone 10, for example, the defect part 5 is CT-scanned to obtain a plurality of two-dimensional data. A method of obtaining three-dimensional shape data of the artificial bone 10 that is acquired and conforming to the defect portion 5 based on the acquired data, and performing NC processing or the like based on the three-dimensional shape data can be employed.

  As shown in FIGS. 2 and 6, a first insertion hole 12 for fixing the connection plate 20 is formed in a predetermined portion of the artificial bone 10 so as to penetrate in the thickness direction of the artificial bone 10. A pipe member 32 of a fixing tool 30 to be described later is inserted into the first insertion hole 12, and the flange portion 34a of the fixing tool 30 is engaged with the inner peripheral edge thereof, and the connecting plate 20 is connected to the outer peripheral edge thereof. One end of the abutment comes into contact.

  The above-mentioned “outer surface” means a surface disposed on the skin of the living body (the scalp covering the skull in this embodiment), and the “inner surface” is the opposite side of the outer surface and protected by the living bone. Means a surface arranged on the side of the living tissue (in this embodiment, brain tissue in the skull, etc.) (the outer surface and the inner surface in the following description have the same meaning).

  Next, the connection plate 20 will be described. The connecting plate 20 is made of a metal material such as titanium, a titanium alloy, stainless steel, a Ni—Ti alloy, a Co—Cr alloy, or a resin material such as polyethylene, polypropylene, polyimide, or a fluorine resin. Among these, titanium or titanium alloy having good biocompatibility and corrosion resistance is preferably used.

  As shown in FIGS. 2 and 3, the connecting plate 20 in this embodiment has a large-diameter circular portion 22 disposed at one end and a plurality of small diameters arranged in a row at a predetermined interval with a smaller diameter. It has the circular part 23 and the connection piece 24 which connects the said large diameter circular part 22 and the small diameter circular part 23, and has comprised the elongate plate shape extended linearly as a whole.

  A second insertion hole 26 for fixing to the artificial bone 10 is formed at the center of the large-diameter circular portion 22, and for fixing to the living bone 3 at the center of each small-diameter circular portion 23. A third insertion hole 28 is formed. Further, as shown in FIG. 3B, tapered recesses 26a and 28a are formed on the outer peripheral edges of the second insertion hole 26 and the third insertion hole 28 so as to be recessed toward the inner surface side. . As shown in FIG. 6, a caulking portion 32 a formed when a pipe member 32 of a fixture 30 described later is cut is engaged with the outer peripheral edge of the second insertion hole 26, and the third insertion hole A head 40a of a screw 40, which will be described later, is engaged with a peripheral edge of the outer surface 28.

  The shape of the connecting plate 20 is not limited to the above shape, but a thin circular plate, a plate having a three-dimensional shape suitable for the shape of the skull, or a polygonal frame such as a quadrangle or a pentagon. Any shape may be used as long as the second insertion hole 26 for fixing to the artificial bone 10 and the third insertion hole 28 for fixing to the living bone 3 can be formed.

  Next, the fixture 30 will be described. As with the connection plate 20, the fixture 30 is made of a metal material such as titanium, titanium alloy, stainless steel, Ni—Ti alloy, Co—Cr alloy, polyethylene, polypropylene, polyimide, fluorine resin, or the like. Titanium or a titanium alloy is preferably used from the viewpoint of biocompatibility and corrosion resistance. Further, in order to suppress electrochemical corrosion, the material of the fixture 30 is preferably the same as the material of the connecting plate 20.

  As shown in FIG. 4, the fixture 30 in this embodiment includes a cylindrical pipe member 32 extending at a predetermined length, and a flange member 34 fixed to one end of the pipe member 32. As shown in FIG. 6, the pipe member 32 has an outer diameter smaller than the inner diameters of the first insertion hole 12 provided in the artificial bone 10 and the second insertion hole 26 formed in the connection plate 20. The flange member 34 protrudes from the center of the flange portion 34a (see FIG. 6) having an outer diameter larger than the inner diameter of the first insertion hole 12, and is press-fitted or inserted into the pipe member 32. And a shaft portion 34b having a possible outer diameter.

  Then, as shown by the arrow in FIG. 4, the shaft portion 34 b of the flange member 34 is press-fitted into the inner periphery of one end portion of the pipe member 32 and / or the coaxial portion 34 b is inserted into the inner periphery of one end portion of the pipe member 32. Then, the flange member 34 is fixed to one end portion of the pipe member 32 by caulking the outer periphery of the one end portion of the pipe member 32, so that the fixture 30 is formed (see FIG. 4).

  On the other hand, the connection plate 20 described above is connected to the artificial bone 10 via the fixture 30. This will be described with reference to FIGS. 2 and 6. First, the pipe member 32 of the fixture 30 is inserted into the first insertion hole 12 of the artificial bone 10 from the inner surface side of the artificial bone 10, and the pipe member is inserted. The other end of 32 is inserted through the first insertion hole 12, and the flange portion 34 a of the fixture 30 is engaged with the inner surface side periphery of the first insertion hole 12 of the artificial bone 10.

  Next, the other end of the pipe member 32 inserted from the first insertion hole 12 is inserted into the second insertion hole 26 of the connecting plate 20, and the portion inserted from the second insertion hole 26 is cut and caulked. The

  At this time, since the pipe member 32 has a cylindrical shape, the peripheral wall of the pipe member 32 is expanded to a flat shape at the time of cutting to form a crimped portion 32a shown in FIG. 6, and the crimped portion 32a is formed into a tapered concave portion. The second insertion hole 26 is engaged with the outer peripheral edge of the second insertion hole 26.

  As a result, the connecting plate 20 and the artificial bone 10 are sandwiched between the flange portion 34a engaged with the inner peripheral edge of the first insertion hole 12 and the crimping portion 32a engaged with the outer peripheral edge of the second insertion hole 26. Thus, one end of the connecting plate 20 and the artificial bone 10 can be connected.

  In this case, since the outer diameter of the pipe member 32 of the fixture 30 is smaller than the inner diameter of the first insertion hole 12 of the artificial bone 10, the inner periphery of the first insertion hole 12 is not strongly pressed. Further, the caulking portion 32a formed by cutting the pipe member 32 is engaged with the outer peripheral edge of the second insertion hole 26 of the connection plate 20 to prevent the fixing tool 30 from coming off from the first insertion hole 12. However, the outer peripheral edge of the second insertion hole 26 is not strongly pressed and engaged. Thus, in this filling device 1, since the connecting plate 20 and the artificial bone 10 are connected by the above-described mounting structure without using a screw or the like, an excessive tightening stress is applied to the artificial bone 10. Therefore, it is possible to reliably prevent the artificial bone 10 from being cracked or cracked.

  Further, in this embodiment, as shown in FIG. 6, there is a predetermined gap between the caulking portion 32 a formed by cutting the pipe member 32 and the outer peripheral edge of the second insertion hole 26 of the connecting plate 20. With the gap S formed, the caulking portion 32 a is engaged with the outer peripheral edge of the second insertion hole 26.

  For this reason, it can suppress that the 2nd penetration hole 26 is strongly pressed by the crimping part 32a, and can reduce the clamping force with respect to the artificial bone 10. FIG. Furthermore, since one end of the connection plate 20 is connected to the first insertion hole 12 of the artificial bone 10 with a small tightening force, the connection plate 20 can be rotated relatively freely. Therefore, as will be described later, when the artificial bone 10 is fitted into the defect 5 of the living bone 3 and the other end of the connecting plate 20 is fixed to the living bone 3, the other end of the connecting plate 20 is connected to the living bone 3. Therefore, the workability of the compensation work can be improved.

  Next, a method of using the filling device 1 of the present invention in which one end of the connecting plate 20 and the artificial bone 10 are connected in advance by the fixing device 30 will be described.

  First, the other end portion of the connecting plate 20 connected to the artificial bone 10 is cut to an appropriate length according to the size and shape of the defect portion 5 to be compensated. Thereafter, as shown in FIG. 1, the artificial bone 10 of the filling device 1 is fitted in the defect portion 5 so as to be applied to the defect portion 5 of the living bone 3, and the defect portion 5 is inserted by the artificial bone 10. To compensate.

  Then, as shown in FIG. 6, the screw 40 is inserted into the third insertion hole 28 at the other end of the connecting plate 20 and tightened so that the head 40 a of the screw 40 has a tapered shape around the periphery of the third insertion hole 28. The other end of the connecting plate 20 is fixed to the living bone 3 by entering the recess 28a and engaging with the outer peripheral edge of the third insertion hole 28 (see FIG. 5).

  As described above, in the filling device 1, since one end of the connection plate 20 is fixed to the artificial bone 10 in advance, the other end of the connection plate 20 is simply fixed to the living bone 3 by a fixing means such as a screw. 5, the artificial bone 10 can be quickly attached to the living bone 3 as shown in FIG. 5, and the workability of the filling work by the artificial bone 10 to the defect portion 5 of the living bone 3 is improved. Can do.

  Moreover, since the crimping part 32a of the fixing tool 30 which comprises this filling tool 1 is arrange | positioned at the outer surface side of the artificial bone 10, the crimping part 32a is not located in the living bone 3. FIG. In this embodiment, since the filling device 1 is used for filling the living bone 3 which is a skull, it is possible to prevent damage to internal tissues such as the brain in the skull.

  Furthermore, since the artificial bone 10 and the living bone 3 are fixed via the connecting plate 20 arranged on the front side thereof, the artificial bone 10 and the living bone 3 even if the artificial bone 10 and the living bone 3 have different thicknesses. The living bones 3 can be reliably fixed.

  Moreover, in this embodiment, since the taper-shaped recessed part 26a is formed in the outer surface side periphery of the 2nd penetration hole 26 of the connection plate 20, as shown in FIG. 6, the caulking part 32a of the pipe member 32 is a taper. The caulking portion 32a is unlikely to protrude to the outer surface side by entering the concave portion 26a and engaging with the second insertion hole 26, and damage to tissues such as the scalp covering the outside of the artificial bone 10 can be prevented. The head 40 a of the screw 40 that fixes the connection plate 20 and the living bone 3 also enters the tapered recess 28 a at the periphery of the third insertion hole 28 of the connection plate 20 and engages with the third insertion hole 28. The protrusion of the head 40a to the outer surface side is suppressed, and damage to the scalp and the like is prevented.

  FIG. 7 shows another embodiment of the living bone prosthesis of the present invention. Note that substantially the same parts as those of the above-described embodiment are denoted by the same reference numerals, and description thereof is omitted.

  As shown in the figure, the living bone prosthetic device 1a (hereinafter referred to as “compensating device 1a”) is provided on the inner peripheral edge of the first insertion hole 12 formed in the artificial bone 10 at the flange portion of the fixing device 30. A recess 12a deeper than the thickness of 34a is formed.

  Then, similarly to the embodiment, the pipe member 32 of the fixture 30 is inserted into the first insertion hole 12 from the inner surface side of the artificial bone 10, and the flange portion 34 a of the fixture 30 is inserted into the inner surface of the first insertion hole 12. When engaged with the side peripheral edge, as shown in FIG. 7, the flange portion 34a is accommodated in the recess 12a and does not protrude to the inner surface side. Damage to brain tissue inside the skull can be prevented.

It is a perspective view which shows one Embodiment of the biological bone prosthetic device of this invention. It is a principal part expansion perspective view of the same bone replacement device. The connection plate which comprises the same bone replacement device is shown, (a) is the top view, (b) is sectional drawing. It is explanatory drawing which shows the fixing tool which comprises the same bone replacement device. It is a perspective view which shows the state which compensated the defect | deletion part of the living bone with the same bone repair device. It is principal part sectional drawing in the use condition of the same bone replacement device. It is a principal part expanded sectional view which shows other embodiment of the biological bone prosthetic device of this invention.

Explanation of symbols

DESCRIPTION OF SYMBOLS 1,1a Prosthetic device 3 Living body bone 5 Defect part 10 Artificial bone 12 1st insertion hole 12a Recess 20 Connection plate 26 2nd insertion hole 26a Tapered recessed part 28 3rd insertion hole 30 Fixing tool 32 Pipe member 32a Caulking part 34a Flange part

Claims (3)

An artificial bone shaped to compensate for a defect in a living bone;
A connection plate that has one end fixed to the artificial bone and the other end fixed to a living bone;
In a living bone prosthesis comprising a fixture for fixing one end of the connecting plate to the artificial bone,
The artificial bone has a first insertion hole for fixing the connection plate,
The connection plate is provided with a second insertion hole for fixing to the artificial bone and a third insertion hole for fixing to the living bone,
The fixture includes a pipe member having an outer diameter smaller than the inner diameters of the first insertion hole and the second insertion hole, and a flange portion having an outer diameter larger than the inner diameter of the first insertion hole formed at one end thereof. And
From the inner surface side of the artificial bone, the pipe member of the fixture is inserted into the first insertion hole, and the flange portion is engaged with the inner surface side peripheral edge of the first insertion hole of the artificial bone. The pipe member inserted from the hole is further inserted into the second insertion hole of the connecting plate, and the portion inserted from the second insertion hole is cut and caulked, whereby the caulking portion is inserted into the second insertion hole. A living bone prosthesis, wherein one end of the connecting plate and the artificial bone are connected to each other by being engaged with a peripheral edge of a hole.   2. The living bone prosthesis according to claim 1, wherein a tapered concave portion that is recessed toward the inner surface side is formed on an outer surface side peripheral edge of the second insertion hole of the connection plate.   3. The living bone prosthetic device according to claim 1, wherein a concave portion deeper than a thickness of a flange portion of the fixing tool is formed on an inner surface side periphery of the first insertion hole of the artificial bone.