JP2009514606A - Container packaging with inhaler accommodation shape - Google Patents

Abstract

Packaging for a container that can be loaded into an inhaler for delivering the contents of the container through the lungs. The package includes a base and a cover, the base having a surface forming a recess for receiving the container. The recess forming surface includes a first region and a second region having a different shape. The first surface region has a shape that supports the container in alignment within the recess, and the second surface region accommodates the first end of the container aligned within the recess, and the container is recessed Extended from the first face area to allow a portion of the inhaler to be inserted therein to accommodate the first end of the container for scooping into the inhaler It has a mouth shape.
[Selection figure] None

Description

  The present invention relates to pharmaceutical packaging, and in particular to packaging for containers that can be loaded into an inhaler and contain pharmaceutical powder for inhalation.

  One method of introducing a drug to a patient is administration through the lungs where the patient inhales the drug by using an inhaler. For example, the drug can be provided in the form of an inhalable powder that fills the interior volume of the container, such as a thin-walled, somewhat hard capsule. Insert the capsule into the inhaler's inhalation chamber, and then operate the inhaler to open the capsule, for example, through to allow the powder to exit the internal volume of the capsule and enter the inhalation chamber The user can then inhale medication from that chamber, usually through the inhaler's chamber capping mouthpiece or nosepiece. After use, capsules that are used or almost free of powder can be removed from the inhaler and discarded.

  One well-known method of packaging capsules is to use a thermoformed blister pack. To place such a pack of capsules in the inhaler, the user can peel the blister cover and remove the capsule from the blister. In that case, the patient may need to repeat this process for additional dosed capsules in additional blisters. In order to remove a capsule from a blister, a patient attempts to remove the capsule with a finger or thumb. This method may not work. This is because the gap between the capsule and the blister wall may be narrow. Alternatively, the patient can use a tool such as a nail file or spoon to remove the capsule from the blister, or the patient can simply remove the capsule from the blister in their hands. You can also. However, these methods also have drawbacks. This is because the capsules are light and tend to be mishandled, and some patients may hate touching the capsules with bare hands, for example, because they hate to mess up the capsules.

  Therefore, it would be desirable to provide a container package that can overcome one or more of these and other disadvantages of the prior art.

  In one form, the present invention provides a package for a unit dose drug or drug formulation. In this case, the packaging includes a feature-shaped recess that can be easily and completely removed from the recess by scooping a dispensing device, such as a device having a mouth that is essentially cylindrical in shape, with the delivery device.

  In one form, the present invention provides a powder that can pass through the hollow section when the body is opened by penetrating the body or otherwise by operating an inhaler loaded with a container for drug administration. A package for an inhaler container having a shell body surrounding an internal cavity filled with a pharmaceutical agent is provided. The package includes a base having a surface forming a recess for receiving the container and a cover for the recess for maintaining the sterility of the container in the recess. The cover can be at least partially removed from above the recess so that the container can be accessed. The recess forming surface includes a first region and a second region having a different shape. The first region is shaped to support the container in alignment within the recess, and the second region accommodates the first end of the container aligned within the recess, from the recess. A mouth extending from a first region that allows a portion of the inhaler to be inserted therein to accommodate a first end of the container for scooping the container within the inhaler It has a part shape or part.

  One advantage of the present invention is that the user loads the inhaler (or other delivery device) with a container (or other unit dose of drug) filled with drug powder without touching the container. It is possible to provide a packaging that can be used.

  Another advantage of the present invention is that it provides a package having a blister that can be easily removed without unnecessarily increasing the overall size of the package and wasting valuable space within the entire package. It can be done.

  Another advantage of the present invention is that it has a blister shaped so that the end of the inhaler can be inserted therein, thereby allowing the container in the blister to be skimmed directly into the inhalation chamber of the inhaler. The packaging can be provided.

  Yet another advantage of the present invention is that it can provide a package from which a container in the blister of the package can be withdrawn or skimmed.

  The foregoing and other advantages and objectives of the present invention, as well as the manner of achieving them, can be better understood by reading the following description of embodiments of the invention with reference to the accompanying drawings, and the invention itself Will be better understood.

  Corresponding reference characters indicate corresponding parts throughout the several views. Although the drawings illustrate embodiments of the present invention, the scale is not necessarily to scale and certain features in some drawings are exaggerated or illustrated in order to better illustrate and explain the present invention. Not shown.

  Referring to FIG. 1, this figure shows a first embodiment of the container packaging of the inhaler of the present invention. The description of the direction of this detailed description with respect to FIG. 1 or any other drawing, such as top or bottom, or top or bottom, is for convenience of explanation and as such is the invention or its optional The components are not intended to be limited to any particular location or space.

  A container package, generally designated by reference numeral 20, holds a plurality of individual containers, each maintained in a sterile condition from the other containers. Each container can be loaded separately into the inhaler so that its contents can be delivered through the lungs. The package 20 is perforated as indicated by reference numeral 22, for example, to allow a user or manufacturer to divide the package 20 into two, more than eight, ten or more small container packages. Can be attached. As will be described in more detail below with reference to FIG. 12, when one of the small containers and packages is opened, the perforations 22 are formed in such a way that the adjacent containers and packages are not opened unintentionally. Can be put. An information panel 21 is provided to identify the contents of the container and allow the user to notice the date it was opened, but it does not contain any additional containers. FIG. 1 also shows an indicator 101 that a patient can use to associate a particular dose with a time point for taking that dose. Indicator 101 is suitable for use by a patient as a tracking or recording tool to track taking a dose at the correct time. In the embodiment of FIG. 1, the indicator 101 allows the patient to track taking the dose by meal (breakfast / lunch / dinner) or by time (morning / day / night). Contains three circles. By way of example, the patient can fill in one circle for each meal to track taking the dose. As another example, a patient can punch one circle for each meal to track taking the dose. The indicator 101 is also suitable for use as a planning tool that allows a patient to “wear” the dose needed for a particular time, such as a work day. To give an example, a patient fills in one of a small container package with noon or lunch, or marks it with a circle, disconnects the package from the package 20, and does not carry the entire package 20 with it. Can also carry that one package on work day. As will be appreciated by those skilled in the art, the indicator 101 is a square shape, or breakfast, lunch, that makes it easy for the patient to associate a particular dose with a time to take that dose. , And letters “B”, “L”, and “D” to indicate dinner, or other forms such as any other mark.

  With further reference now to FIGS. 3-8, these drawings show one such small container package 20 'holding one container. Package 20 'shows all such packages formed together to provide the container holding capacity of package 20 of FIG. The package 20 ′ includes a base 24 having a recess 26 containing a container, a cover 28 connected to an upper surface 29 of the base 24, such as an adhesive continuously applied around the recess 26. The cover 28 completely covers the recess 26 in order to keep the container, generally indicated by reference numeral 60, in the recess in a sterile state.

  In the figure, the container 60 is shown as a capsule having a thin wall shell formed by a body member 63 and a cap member 67. The body member 63 has a substantially cylindrical side wall 64 that extends to a rounded closed end 65. The cap member 67 has a substantially cylindrical side wall 69 and a rounded closed end 71. The cap member fits over the open end of the body member 63 during manufacture and is maintained in place in any suitable manner known to those skilled in the art, such as by an annular snap fit. Otherwise, the hollow internal volume 73 formed by the integral cap member 67 and body member 63 is a powder generally indicated by reference numeral 75 that is suitable for user inhalation during manufacture of the container. Is satisfied by. Powder 75 contains an agent that is desired to be delivered through the lung, which contains the active ingredient and usually one or more excipients. The orientation of the container in the figure is merely exemplary and is not intended to indicate the required orientation.

  The cap member 67 and the body member 63 may be penetrating elements forming one, two or more holes therein, or two members that are separated in the inhaler during use of the inhaler, or It is made of any suitable material capable of opening one or both such members, such as one or both of the members being separated by a slice. Such an opening allows the powder 75 to pass through the internal volume 73 as appropriate. For example, the capsule shell can be made from gelatin, hydroxypropylmethylcellulose (HPMC), cellulose, water-soluble polysaccharides (eg, pullulan) or gelatin / PEG as is well known to those skilled in the art. One suitable fillable capsule is sold by Qualicaps, Whitsett, NC and is known as Posilok® capsule.

  Other shaped containers can also be used with the packaging of the present invention. For example, instead of the capsule-shaped container shown, the container shape can be shorter or rounded, or can be used in a different way, such as a receiving recess covered with a film. It may be what was done.

  3 to 8, the base portion 24 is separated from the cover 28. The base 24 is generally manufactured from a single piece of plastic, such as thermoformed plastic, including a recess 26 supplied as a blister. Plastic blister pack designs are well known and have a lightweight, flexible, and possibly transparent base with a relatively low cost and sufficient rigidity to provide the desired level of protection for the container. Can be provided. In other embodiments within the scope of the present invention, a base is provided that includes a more substantial or thicker base having a recess molded or formed therein to form a container wall. One or more other materials can be used to do this. For example, cold form aluminum technology can be used to produce a suitable base.

  The top surface 29 of the base 24 is substantially planar and includes a protruding peel tab 30 to facilitate gripping and facilitate subsequent removal of the cover 28. The recess 26 is formed from a contoured surface that is particularly adapted to the periphery of the container housed therein, as well as the intended scooping or withdrawal of the container. In the figure, the recess 26 fits the full height of the container 60 to accommodate manufacturing variations, so that there is a slight gap above the container and thereby flatten the cover 28 over the recess. It has sufficient depth to be able to be stored. If the cover can accommodate the projection of the container on the top surface, other recess depths of a shallower depth can be used within the scope of the present invention.

  The contour surface forming the recess 26 is sloped downward at the distal end to provide a generally upstanding end surface or container stop surface 31. This surface will probably include undercuts, such as undercuts or from about 5 degrees to about 1 degree (eg, about 4 degrees, 3 degrees or 2 degrees) from the vertical direction to facilitate manufacturing. While providing its stop function, it can deviate from the correct vertical direction. As used herein, the terms distal and proximal refer to the position relative to the position of the inhaler when inserted into the inhaler-accommodating shape of the recess described in more detail below for scoop removal of the container. Means. In this case, for example, the proximal end of the recess means the position where the inhaler is inserted, and the distal end of the recess means the end of the recess farthest from the proximal end. The container stop surface 31 is for contacting the container 60 when the container can be pushed away from the inhaler while the container is being taken out from the recess 26.

  In the embodiment of FIG. 5, immediately adjacent to the distal end, the contoured concave surface includes an optional surface 33 that is inclined slightly downward from the top surface 29. This surface 33 transitions to a surface 34 that projects sufficiently inward to provide a rib that maintains alignment of the container within the recess 26. Since the surface 29 has an angle, automatic container loading during manufacture is facilitated. In one embodiment, an angle of about 30 degrees to about 60 degrees or more from the horizontal plane can be used. The surface 34 can be characterized by a rib that is illustrated in a continuous fashion extending approximately one third of the longitudinal length of the recess 26. In other embodiments, there may be a plurality of ribs or tabs on either or both sides of the recess, or the ribs or tabs may not be used at all and are not continuous in the longitudinal direction. Different alignment members, such as members, can be provided.

  FIG. 5 also shows an inhaler stop surface 51. The inhaler stop surface 51 is a surface having a plurality of surfaces that cannot push the inhaler in the direction away from the recess 26 before that. The inhaler stop surface 51 is inclined so that it is easy to move or scoop the container 60 from the recess 26 to the inhaler. The inhaler stop surface 51 is formed in a region where the recess 26 transitions from wide to narrow at about 2/3 of the longitudinal length measured from the proximal end to the distal end of the recess 26. Is done.

  In the case of the embodiment of FIGS. 12 to 15, the surface 33 is not used and no ribs are used on the surface 34.

  The surface 34 forms a far recessed area 36 that is designed to fit the container 60 tightly. This fit is usually not a friction fit or a press fit. However, such press fits are included within the scope of the present invention. The container 60 is located on the bottom concave surface 37 below the concave region 36 and extends in a direction close thereto. If the radius of curvature of the transition from the container stop surface 31 to the bottom surface 37 is significantly greater than the radius of curvature of the container end to which it faces, the container 60 is packaged 20 if the inhaler 90 attempts to skim the container. Can be extruded from. Preferably, the ratio of the radius of curvature of the transition to the radius of curvature of the container is 1.3 or less, preferably less than or equal to 1. For example, the embodiment of FIG. 6 shows a package 20 in which the transition from the container stop surface 31 to the bottom surface 37 has a radius of curvature that is less than the radius of curvature of the container end that it faces. For example, the embodiment of FIGS. 12-15 shows a package 20 in which the transition from the container stop surface 31 to the bottom surface 37 has a radius of curvature that is greater than the radius of curvature of the container end to which it faces. In the latter embodiment, the transition radius of curvature is 4.23 mm for a container having an end radius of curvature of 3.5 mm.

  The proximal end of the recess 26 includes a mouth or scoop shape, indicated generally by the reference numeral 40. The width of the mouth 40 extends from the width of the recessed area 36 and is sized and shaped to fit an inhaler or device for use with a container contained in the package 20 '. . In the case of an inhaler having a substantially cylindrical outer periphery around the inhalation chamber as shown in FIGS. 9 to 11, in order to scoop up the container 60 from the recess, the peripheral end is placed in the recess 26. It can be inserted and the mouth 40 of the recess forming surface can be smoothly rounded with the front edge portion 41 curved at the upper surface 29. The wide width of the mouth 40 creates a lateral space from the side of the aligned container 60 so that the inhaler can be easily inserted around the container during scooping, and therefore The nearer part of the container not disposed between the surfaces 34 has a larger lateral space including the contour surface of the recess 26 than the lateral space of the farther part of the container including the surface 34. . Therefore, the width of the mouth 40 is larger than the diameter or width of the inhaler, and therefore larger than the diameter or width of the container 60. Further, the width of the mouth 40 is larger than the diameter or width of the recess 26 between the surfaces 34. In the case of the embodiment of FIGS. 12-15, the width of the mouth 40 at the top surface 29 is 10-20 mm or more (eg 13.00 mm), while the recesses 26 between the surfaces 34 are The width may be 8 to 12 mm (for example, 9.03 mm). If the exemplary embodiment is adapted for larger packaging, the ratio of the mouth 40 to the surface 29 may be 1-1.5, and the ratio of the width of the recess 26 to the container 34 is 1-1.5. It may be 1.5. Rake shapes other than those shown can be used instead within the scope of the present invention. This can be done especially when using different inhaler configurations.

  In the case of the embodiment of FIGS. 5 to 11, the mouth 40 is inclined downwardly from the front edge 41 as a convex upper region 43 that transitions at a curved point 45 into the concave lower region 47. . In the case of the embodiment of FIGS. 12 to 15, the concave lower region 47 extends to the front edge 41 at the surface 29. The tilt should be sufficient to facilitate the introduction of the inhaler into the mouth 40. In the case of the embodiments of these drawings, the inclination may be 30 to 60 degrees from the vertical plane.

  The bottom of the concave portion 47 is integrated with the bottom surface 49 of the portion closer to the concave portion 26. At least one of the bottom surface 49 and / or 37 supports the container 60. In one embodiment, the bottom surface 49 is located at the same depth from the top surface 29 as the bottom surface 37 of the recess. In other embodiments, the bottom surface 49 is located at a depth slightly below the depth of the bottom surface 37 of the recess from the top surface 29.

  The radius of curvature of the concave portion 47 at the proximal end of the recess is greater than the radius of curvature of the proximal end of the capsule. For example, the radius of curvature of the lower region 47 of FIGS. 12-15 is about 2 of the radius of curvature of the container (6-9 mm (eg, 6.36 mm) and about 3-4 mm (eg, 3.5 mm, respectively)). It may be doubled. This curvature allows the user to pull the container 60 from the recess 26 in the near direction if the user does not want to scoop the inhaler. This is because if the container moves in the above direction during such a pulling operation, the container moves obliquely upward through the concave portion 47 and then the convex portion 43. Within the scope of the present invention, this oblique movement function capable of pulling the capsule can be provided by other slope shapes, such as a planar shape, an inclined end face, or does not use this function at all. You can also

  In the case of the illustrated embodiment, the mouth portion 40 continues farther to the point where the surface 34 is formed, so that the recess 26 has a depth or height where the top of the rib 34 is located. It has a shape like a mushroom. Preferably, the mouth 40 and the recess 36 merge and transition in at least one transition plane, such as, for example, the face 39 of FIG. 13 (eg, planar or concave with respect to the mouth). . Preferably, the transition surface 39 (from the bottom surface 37 of the recess to the top surface 29) is inclined in a direction away from the mouth 40. In the case of FIG. 13, the slope of the figure is about 30-60 degrees from the vertical plane. Since the inwardly projecting ribs on the surface 34 and the surface 34 cannot extend upward to the top of the recess 26, and more particularly cannot extend to the upper surface 29 of the base, the recess 26 has a proximal end. A bullet shape design can be taken at the top surface 29 forming the more rounded contour of the bullet.

  The cover 28 can be formed and attached to the base by various methods known to those skilled in the art. For example, the cover 28 can be made of any well-known material or combination thereof and can be designed to be easily and easily removed while avoiding unintended access. Suitable materials known to those skilled in the art include paper, foil or plastic sheet and combinations thereof. The embodiment of FIG. 3 shows a cover 28 of lift-peel type material, in which case it can be peeled in order to expose the full longitudinal length and width of the recess 26. The cover can be removed completely. In other embodiments, other cover techniques may be used as long as the container 60 can be sufficiently exposed in the recess 26 to be accessible by the inhaler through the mouth 40. . For example, a cover having a first peelable portion made of backing paper and a second portion of a fragile foil that can be torn and peeled separately from above the recess after removing the first peelable portion However, it can be used within the scope of the present invention.

  FIG. 12 shows another embodiment of the packaging of the present invention. The package 120 of FIG. 12 includes perforations 122 that can separate the package 120 into a plurality of small container packages, such as the container package of FIG. In the case of the embodiment of FIG. 12, the cover 28 includes a melting or sealing region that forms a halo around the recess 26. In FIG. 12, the sealed area is represented by a knotted diamond-shaped pattern, referred to herein as a seal or sealed area 128. The seal 128 is formed, for example, by heat sealing or melting that region of the cover 28 on the upper surface 29 of the base 24. The seal 128 holds the cover 28 in place and helps maintain the container 60 in the package 120. As can be seen in FIG. 12, the cover 28 includes an opening boundary 129 that surrounds the seal 128 between the seal 128 and the perforation 122. The unsealing boundary 129 provides a break area where the cover 28 can be peeled off or otherwise separated from the top surface 29 of the base 24, for example, in a manner as shown in FIG. The resistance in separating the cover 28 from the top surface 29 of the base 24 within the sealed area 128 is greater than the resistance to do so within the opening boundary 129, but preferably the sealed area 128 is peeled from the top surface 29 by the user. Or are designed to be separated by other methods. In the case of the embodiment of FIG. 12, starting from the proximal end towards the distal end of the recess 26, the sealing surface area increases when the cover 28 is peeled off or otherwise separated. If so, the resistance of the sealing region 128 towards the distal end is greater. The opening boundary 129 provides an area adjacent to the perforation 122 that can be easily removed to prevent the cover of adjacent packaging from peeling or separating. When the cover 28 is peeled or otherwise separated from one of the small container packages of the package 120, the cover 28 is easily separated at the opening boundary 129, and the perforation 122 causes one container Only the cover 28 for the package is peeled off. Alternatively, if the sealing region 128 extends to the perforation 122, removing the cover 28 from one of the small container packages of the package 120 peels or removes the cover 28 from the adjacent container package. To be separated, the container will be exposed to non-sterile conditions before it is ready for use. The opening boundary 129 helps to prevent inadvertent opening of an adjacent container package when one container package is opened.

  9-11 illustrate a container package 20 'for use with an inhaler, which is indicated abstractly in the associated member by reference numeral 90. FIG. Various inhaler designs are well known, including those disclosed in US Pat. No. 6,732,732, which is hereby incorporated by reference, and can be used as inhaler 90. However, the overall structure of the inhaler is not critical to understanding the present invention. An aspect associated with the inhaler is that the inhaler has a member that can be inserted into the mouth 40 to scoop the container 60. Preferably, the inhaler member preferably includes a loading opening of the inhalation chamber, as in the case of inhaler 90 shown abstractly herein, but need not be so configured. .

  By orienting the wrapping 20 ′ so that the cover 28 does not face downward and preferably so that the base 24 is positioned horizontally, the user initially exposes at least a portion of the container 60. In addition, the cover 28 can be peeled or otherwise removed. It will be appreciated that the cover 28 can be completely removed before scooping the container. This is because the container stop surface 31 at the distal end of the recess 26 serves as a backstop for the container 60 during insertion of the inhaler. This backstop can be provided in other ways by a cover that has been partially removed.

  The inhaler tip 96 can then be manipulated to move downwardly in a direction away from the inhaler 90 so that the inhaler tip 96 first enters the mouth 40 and typically slides along the mouth 40. The tip 96 includes a central bore that opens directly into the suction chamber 94 of the inhaler 90. This chamber is formed by the inner wall 95 of the inhaler body 92. As the inhaler 90 continues to move as described above, the tip 96 slides under the rounded end of the container 60. Because such an end enters the central hole at the tip and then engages the inner wall 95 to continue into the chamber 94, the container is camped upwards. is there. As the user continues to operate the inhaler 90 so as to move in a substantially away direction and as shown in FIG. 10, the container 60 can further enter the inhalation chamber and tilt slightly upward relative to the recess 26. While the inhaler is moving in this manner, the container stop surface 31 provides a stop against which the container can abut to prevent the container from coming out of the recess 26. This relative movement of the inhaler 92 and the base 24 shown in FIGS. 9 to 11 is achieved by moving the inhaler 90 relative to the stationary package or while the package is moving relative thereto. It can be understood that this can be done by holding on or by a combination of both. FIG. 11 shows a package that is tilted, but it is helpful to tilt the package, but it is not necessary to tilt to successfully remove the capsule from the package containing the inhaler. I want to be.

  For example, as shown in FIG. 11, the container 60 is moved into the inhaler chamber 94 so that the container does not fall when the inhaler is located horizontally in the longitudinal direction or is oriented more upright. As such, after sufficient movement of the inhaler 90 and / or base 24, the inhaler can be moved away from the package 20 ', which is assembled over the inhalation chamber and used in a conventional manner. After removal from the inhaler, the used capsule is discarded rather than being returned to the blister for later processing. Subsequent use of the inhaler with the other capsule package 20 'can be made until the capsule container package 20 is completely used up.

  While the invention having a preferred design has been shown and described, it can be modified without departing from the spirit and scope of the invention. This application is therefore intended to cover any variations, uses, or adaptations of the invention using its general principles. Furthermore, this application is intended to cover such departures from the invention that fall within the well-known or routine use of the industry to which the invention pertains.

It is a perspective view of the top part of 1st Embodiment of the container packaging of this invention. FIG. 2 is a perspective view of the bottom of the container package of FIG. 1, not showing the container in the packaging recess for the sake of simplicity. FIG. 2 is a perspective view of the top of the cross section of the container package of FIG. 1, shown separated from the rest of the package. This packaging section is shown with a cover that is kept in its sterile condition with a part peeled away to expose a part of one container contained therein, the outline of the container being It is indicated by a chain line. FIG. 4 is a drawing of the top of the base of the container package of FIG. 3, not showing the cover maintained in a sterile condition completely removed from the base, and illustrating the contained container. FIG. 5 is a perspective view of the top of the base of FIG. 4 without showing the container. It is the longitudinal cross-sectional view of the base and container which were cut | disconnected along 6-6 line of FIG. FIG. 7 is a cross-sectional view taken along line 7-7 in FIG. 4. It is the cross-sectional view cut | disconnected along 8-8 line of FIG. FIG. 7 is a view similar to FIG. 6 in which the end of the inhaler conceptually shown in the first stage of scooping the container therefrom is inserted into the recess in the base. FIG. 10 is a side view similar to FIG. 9 at an intermediate stage of an inhaler that scoops the container from the package. FIG. 10 is a view similar to FIG. 9 after scooping the container from the package into the inhaler. It is a perspective view of the top part of the 2nd Embodiment of this invention. It is a longitudinal cross-sectional view of the base and container cut | disconnected along 13-13 line | wire of FIG. FIG. 13 is a top perspective view of the cross section of the container package of FIG. 12 separated from the remainder of the package. It is a longitudinal cross-sectional view of the base and container cut | disconnected along 15-15 line of FIG.

Claims (18)

Packaging for unit dosage forms,
A base having a recess forming surface that forms a recess containing the unit dosage form;
A cover for the recess, the cover being removable at least in part to allow access to the unit dosage form;
The recess forming surface includes a first surface region and a second surface region having a different shape, wherein the first surface region supports the unit dosage form in alignment within the recess. Wherein the second face region accommodates a first end of the container aligned within the recess and is skimmed from the recess into a delivery device. A package having a mouth shape that extends from the first face region to allow a portion of the delivery device to be inserted therein to accommodate an end. A package for an inhaler container, wherein the container has a shell body surrounding an interior hollow portion filled with a powdered drug, and the powdered drug is penetrated by the body Or can be delivered from the hollow portion when opened in other ways by the action of an inhaler loaded with the container for drug administration,
A base having a recess forming surface for forming a recess for housing the container;
A cover for the recess for maintaining the container in a sterile condition in the recess, the cover being at least partially removable so that the container can be accessed;
The recess forming surface includes a first region and a second region having a different shape, and the first region has a shape that supports the container in an aligned state in the recess, A second region accommodates the first end of the container that is aligned within the recess, and the first end of the container for scooping the container from the recess into the inhaler A package having a mouth extending from the first region so that a portion of the inhaler can be inserted therein.   The package of claim 2, wherein the second region comprises a concave surface characterized by a radius of curvature that is greater than the radius of curvature of the proximal end of the container.   4. A package as claimed in claim 3, wherein the second region comprises a concave surface characterized by a radius of curvature twice that of the proximal end of the container.   The packaging of claim 3, wherein the first region includes a concave surface characterized by a radius of curvature that is less than the radius of curvature of the second region.   The mouth includes an inclined surface facing toward the first end of the container, the inclined surface includes a concave portion, and the inclined surface has an angle of 30 to 60 degrees from a vertical surface. The packaging according to claim 2, comprising:   The mouth includes an inclined surface facing toward the first end of the container, the inclined surface includes a concave portion and a convex portion, and the concave portion is the convex in the concave portion. The packaging according to claim 2, which is deeper than the shaped part.   A curved point between the concave portion and the convex portion along the longitudinal section of the concave portion passing through the length of the central portion of the container aligned within the concave portion is a central portion of the depth of the concave portion. The package of claim 7 disposed within.   The mouth includes a concave surface facing the first end of the container and extending below the height of the central portion of the container, the concave surface being the first of the container. 3. A package according to claim 2, having a curvature with a radius greater than the radius of curvature of the end, whereby the concave surface can be raised when the container is skimmed from the recess.   A third region forming a container stop surface for contacting the second end of the container aligned within the recess while the recess forming surface is scooping the container from the recess The packaging according to claim 2, comprising:   The bottom end of the third region transitions to the bottom of the recess along a surface having a certain radius of curvature, and the ratio of the radius of curvature of the transition surface to the radius of curvature of the second end of the container is 1. The package according to claim 10, which is smaller than .3.   The bottom end of the third region transitions to the bottom of the recess along a surface having a radius of curvature, the radius of curvature of the transition surface being less than the radius of curvature of the second end of the container; The packaging according to claim 9.   The package of claim 12, wherein the slope of the third region is 5 degrees from a vertical plane.   The packaging according to claim 2, wherein the recess forming surface has an inhaler stop surface.   The packaging according to claim 1, wherein the recess forming surface comprises a thermoplastic blister.   The package according to claim 1, wherein the cover has a layer connected to the base that can be peeled from above the entire recess to completely expose the container in the recess.   The kit provided with the packaging according to any one of claims 2 to 16, wherein a container containing an inhalable powdered drug and an inhaler are disposed therein. A method for loading an inhaler chamber of an inhaler comprising a container filled with a powdered drug without touching the container,
Supplying a container packaged in a blister pack, the blister pack including an asymmetric recess formed by a base of the blister pack, the lower portion of the recess being a first An end portion and a second end portion, and a portion of the recess close to the first end portion has a first width and serves as a mouth portion; A portion of the adjacent recesses having a width narrower than the first width for alignment with the container, and the mouth having a size and shape to accommodate the tip of the inhaler;
Opening the blister pack cover to expose at least the mouth region of the recess and at least the end of the container;
Inserting the tip of the inhaler having an opening leading to the suction chamber into the mouth region of the recess;
Moving the inhaler and blister pack relative to each other to scoop the container out of the recess and through the opening of the inhaler for entry into the inhalation chamber. Method.

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