JP2009035500A - Cosmetics and external preparation for skin - Google Patents

Abstract

The object of the present invention is to use water as a medium that has both hydrophilic and lipophilic functions, is smooth to the touch, does not feel moist and sticky, is well-fitted to the skin, and does not use a surfactant. It can also be blended into cosmetics or external preparations for skin, and has a highly stable diester, and feels smooth and moist and non-sticky, containing the diester, and is well-fitted to the skin. And the provision of cosmetics or skin external preparation excellent in stability.
A diester of a dicarboxylic acid represented by Chemical Formula 1 and a polyoxyethylene monoalkyl ether represented by Chemical Formula 2 is used.
(Chemical formula 1)
HO-CO-R1-CO-OH
(In the formula, R1 represents a linear or branched hydrocarbon group having 4 to 10 carbon atoms)
(Chemical formula 2)
R2- (OCH2CH2) n-OH
(Wherein R2 is a linear, branched or cyclic hydrocarbon group having 1 to 12 carbon atoms, and n represents an integer of 2 to 11)
[Selection figure] None

Description

The present invention relates to a cosmetic or a skin external preparation excellent in feeling of use, stability and the like, comprising a diester of a dicarboxylic acid represented by Chemical Formula 1 and a polyoxyethylene monoalkyl ether represented by Chemical Formula 2.
(Chemical formula 1)
HO-CO-R1-CO-OH
(In the formula, R1 represents a linear or branched hydrocarbon group having 4 to 10 carbon atoms)
(Chemical formula 2)
R2- (OCH2CH2) n-OH
(Wherein R2 is a linear, branched or cyclic hydrocarbon group having 1 to 12 carbon atoms, and n represents an integer of 2 to 11)

Functions required for ester oils for cosmetics and external preparations for skin include excellent usability, superior aging and oxidation stability, and the like. Recently, in addition to these functions, it has both hydrophilic and lipophilic functions, and can be added to water-based cosmetics and skin preparations that do not use surfactants, and is smooth and moist. Accordingly, there has been a demand for having a feeling of use that is not sticky and that is familiar to the skin. As such ester oil agents, polyoxyethylene dicarboxylic acid esters such as diethoxyethyl succinate described in JP-A Nos. 2001-206812 and 2001-240526 have been proposed. The compounds exemplified in the examples of these patents include three kinds of diethoxyethyl succinate, diethoxyethyl adipate and diethyl carbitol sebacate.
JP 2001-206812 A JP 2001-240526 A

  However, these patents do not mention the water-solubility of the ester, but the water-solubility of diethoxyethyl adipate and diethyl carbitol sebacate is as low as 1% or less. There was a limit to blending into cosmetics and skin external preparations. In addition, although diethoxyethyl succinate is excellent in water solubility, it has poor lipophilicity, so it cannot be said that the touch surface is sufficient, and the pH stability of the aqueous solution is poor. Thus, these esters do not necessarily satisfy all of the functions required for ester oils for cosmetics and external preparations for skin. From such a background, it has both hydrophilic and lipophilic functions, is smooth, moist and does not feel sticky, is well-familiar with the skin, and uses a surfactant-free water medium as a cosmetic. In addition, there has been a demand for an ester oil agent that satisfies all of the requirements of being able to be blended into an external preparation for skin, aging and oxidation stability, and excellent pH stability in an aqueous solution system.

  The problem to be solved by the present invention is that it has both hydrophilic and lipophilic functions, is smooth, moist and non-sticky, has a feeling of familiarity with the skin, and does not use a surfactant. It can also be blended in cosmetics and skin external preparations using water as a medium, and is superior in aging and oxidation stability, ester oil agent excellent in pH stability in an aqueous solution system, and feeling of use and stability containing the ester oil agent The object is to provide a cosmetic or an external preparation for skin.

As a result of intensive studies to solve the above problems, the present inventors have found that diesters of dicarboxylic acid represented by Chemical Formula 1 and polyoxyethylene monoalkyl ether represented by Chemical Formula 2 are hydrophilic and lipophilic. It has both functions, is smooth to the touch, moist and has no stickiness, is well-familiar with the skin, and is used in cosmetics and skin preparations that use water as a medium without using surfactants. The present invention was completed by finding that it was excellent in aging stability, oxidation stability, and pH stability in an aqueous solution system. That is, the present invention provides a cosmetic or skin external preparation containing the above-mentioned diester that is smooth to the touch, moist and non-sticky, has a good fit on the skin, and is excellent in stability. Is.
(Chemical formula 1)
HO-CO-R1-CO-OH
(In the formula, R1 represents a linear or branched hydrocarbon group having 4 to 10 carbon atoms)
(Chemical formula 2)
R2- (OCH2CH2) n-OH
(Wherein R2 is a linear, branched or cyclic hydrocarbon group having 1 to 12 carbon atoms, and n represents an integer of 2 to 11)

  The diester of the present invention has both hydrophilic and lipophilic functions, is smooth to the touch, has no moist and sticky feeling, is well-familiar with the skin, and does not use a surfactant-free water. Cosmetics or skin that can be blended in cosmetics or skin external preparations as a medium, and have excellent aging and oxidation stability, pH stability in an aqueous solution system, and excellent usability and stability by containing this. An external preparation can be obtained.

In order to express the excellent function of the present invention, it is essential to use a diester of a dicarboxylic acid represented by Chemical Formula 1 and a polyoxyethylene monoalkyl ether represented by Chemical Formula 2.
(Chemical formula 1)
HO-CO-R1-CO-OH
(In the formula, R1 represents a linear or branched hydrocarbon group having 4 to 10 carbon atoms)
(Chemical formula 2)
R2- (OCH2CH2) n-OH
(Wherein R2 is a linear, branched or cyclic hydrocarbon group having 1 to 12 carbon atoms, and n represents an integer of 2 to 11)

As the dicarboxylic acid represented by Chemical Formula 1 constituting the diester, R1 is a dicarboxylic acid representing a linear or branched hydrocarbon group having 4 to 10 carbon atoms. Specifically, saturated linear dicarboxylic acids such as adipic acid, pimelic acid, suberic acid, azelaic acid, sebacic acid, dodecanedioic acid; 2,2,4-trimethyladipic acid, 2,4,4-trimethyladipic acid And saturated branched chain dicarboxylic acids. Of these, adipic acid, azelaic acid, sebacic acid, and dodecanedioic acid are preferred from the viewpoints of economy and reactivity, and adipic acid is most preferred.

  On the other hand, as a polyoxyethylene monoalkyl ether represented by Chemical Formula 2 constituting a diester, R2 is a linear, branched or cyclic hydrocarbon group having 1 to 12 carbon atoms, and n is an integer of 2 to 11 It is. Examples of straight, branched or cyclic hydrocarbon groups having 1 to 12 carbon atoms include methyl group, ethyl group, propyl group, isopropyl group, n-butyl group, isobutyl group, n-pentyl group, and n-hexyl group. Cyclohexyl group, n-octyl group, 2-ethylhexyl group, n-decyl group, n-dodecyl group, and the like. From the reactivity during esterification, performance of diester, economy, etc., methyl group, ethyl Group is preferred, and ethyl group is particularly preferred. Regarding n in Chemical Formula 2, when n in the formula is 1, it is not preferable because the water solubility of the resulting diester deteriorates. On the other hand, when n in the formula is 12 or more, the water solubility increases. Therefore, the touch becomes slightly heavy, and there is a problem that the feeling of use when used for cosmetics or skin external preparations deteriorates. Therefore, n in the chemical formula 2 is preferably an integer of 2 to 11. Furthermore, n is preferably 2 or 3 from the viewpoints of economy, reactivity, etc., and the polyoxyethylene monoalkyl ether represented by Chemical Formula 1 is preferably diethylene glycol monoethyl ether or triethylene glycol monoethyl ether. Most preferred is monoethyl ether.

  In addition, the balance between water solubility and lipophilicity of the diester obtained varies depending on the type of dicarboxylic acid and ethylene glycol monoalkyl ether used, but if the water solubility is too high, it is not preferable in terms of touch, and conversely, the lipophilicity is high. Then, the water solubility becomes insufficient. For this reason, in order to obtain a preferable feel with lipophilicity while ensuring water solubility, it is preferable to increase the number of n in Chemical Formula 2 along with the increase in the carbon number of R1 in Chemical Formula 1 dicarboxylic acid. The number of n varies depending on the carbon number of R2 in Chemical Formula 2, but specifically, when R2 is ethyl, n is 2 to 4 with respect to 4 carbon atoms of R1, and with respect to 6 carbon atoms of R1. It is preferable that n is 3 to 7, n is 4 to 9 with respect to carbon number 8 of R1, and n is 5 to 11 with respect to carbon number 10 of R1. From the above, as the diester of the present invention, bis (diethylene glycol monoethyl ether) adipate, bis (triethylene glycol monoethyl ether) adipate, and bis (triethylene glycol monoethyl ether) azelate are preferable. (Diethylene glycol monoethyl ether) is most preferred.

  The production method of the diester of the present invention is not particularly limited, but economically when the following production method, that is, esterification reaction of raw material dicarboxylic acid and polyoxyethylene monoalkyl ether at 150 to 260 ° C. without solvent is economical. It can be advantageously manufactured. The charging ratio of the dicarboxylic acid and the polyoxyethylene monoalkyl ether during the esterification reaction is preferably 1.6 to 6, more preferably 2 to 4 in molar ratio from the ester production rate and economical viewpoint. is there. Esterification can also be performed using a catalyst and a solvent. When a catalyst such as an acid catalyst is used, a general acid catalyst such as p-toluenesulfonic acid, sulfuric acid, hydrochloric acid, methanesulfonic acid, boron trifluoride diethyl ether complex, titanium alcoholate, or solid acid catalyst can be used. . When using a solvent, commonly used solvents such as toluene and heptane can be used. After completion of the esterification reaction, the target diester of the present invention can be obtained by purification without purification or by a conventional purification method such as vacuum distillation, washing with water, steam deodorization, activated carbon treatment or the like. During production, in addition to diesters, monoesters and unreacted polyoxyethylene monoalkyl ethers may remain in the diesters. Even if monoester or unreacted polyoxyethylene monoalkyl ether remains, it may not be a problem depending on the use, but when used as an oil agent described later, particularly for cosmetics or skin external preparations. The purity of the diester is desirably 80% by weight or more, preferably 90% by weight or more, and more preferably 95% by weight or more.

  The diester of the present invention thus obtained has both hydrophilic and lipophilic functions, which are preferable functions as an oil for cosmetics or external use for skin, and is smooth, moist and non-sticky. Good balance with skin, good compatibility with skin, cosmetics and skin preparations with water medium, aging and oxidation stability, and excellent pH stability in aqueous solution. Since it is a thing, it is excellent as an oil agent for cosmetics or a skin external preparation. The diester of the present invention can be used as it is as an oil for cosmetics or external preparations for skin, but is used as an antioxidant, an oily base for other cosmetics or external preparations for skin described later, a moisturizing agent, a feeling improver, etc. It can also be used as a mixture. As the antioxidant, tocopherol derivatives such as tocopherol (vitamin E) and tocopherol acetate; BHT, BHA; gallic acid derivatives such as propyl gallate; vitamin C (ascorbic acid) and / or a derivative thereof can be used. When the antioxidant is contained, the content of the antioxidant is preferably 0.0001 to 0.1% by weight.

  The cosmetic or external preparation for skin containing the diester of the present invention is smooth to the touch, has no moist and sticky feeling, is well-familiar to the skin, and has excellent stability. The blending amount of the diester of the present invention into the cosmetic or skin external preparation is not particularly limited, but is preferably about 0.01 to 50% by weight, more preferably 0.05 to 50% by weight as the diester. Further, in the cosmetic or skin external preparation of the present invention, additive components generally incorporated into the cosmetic or skin external preparation as necessary, for example, an oily base, a moisturizing agent, a feeling improver, a surfactant, Polymer, thickening / gelling agent, solvent, propellant, antioxidant, reducing agent, oxidizing agent, preservative, antibacterial agent, chelating agent, pH adjuster, acid, alkali, powder, inorganic salt, UV absorption Agent, whitening agent, vitamins and derivatives thereof, anti-inflammatory agent, anti-inflammatory agent, hair growth agent, blood circulation promoter, stimulant, hormones, anti-wrinkle agent, anti-aging agent, squeeze agent, cooling sensation agent, warm feeling Agents, wound healing promoters, stimulation relieving agents, analgesics, cell activators, plant / animal / microbe extracts, antipruritic agents, exfoliating / dissolving agents, antiperspirants, refreshing agents, astringents, enzymes, nucleic acids, fragrances, A pigment | dye, a coloring agent, dye, a pigment, water, etc. can be mix | blended.

  Examples of these additive components include cetanol, myristyl alcohol, oleyl alcohol, lauryl alcohol, cetostearyl alcohol, stearyl alcohol, aralkyl alcohol, behenyl alcohol, jojoba alcohol, chimyl alcohol, seraalkyl alcohol, batyl. Higher alcohols such as alcohol, hexyldecanol, isostearyl alcohol, 2-octyldodecanol, dimer diol; aralkyl alcohols and derivatives such as benzyl alcohol; lauric acid, myristic acid, palmitic acid, stearic acid, isostearic acid, behenic acid, undecylen Acid, 12-hydroxystearic acid, palmitooleic acid, oleic acid, linoleic acid, linolenic acid, erucic acid, docosahexaenoic acid, ethyl Higher fatty acids such as cosapentaenoic acid, isohexadecanoic acid, anteisohenicosanoic acid, long-chain branched fatty acid, dimer acid, hydrogenated dimer acid, and their aluminum salts, calcium salts, magnesium salts, zinc salts, potassium, sodium salts, etc. Metal soaps, and nitrogen-containing derivatives such as amides; liquid paraffin (mineral oil), heavy liquid isoparaffin, light liquid isoparaffin, α-olefin oligomer, polyisobutene, hydrogenated polyisobutene, polybutene, squalane, olive-derived squalane, squalene , Hydrocarbons such as petroleum jelly and solid paraffin; candelilla wax, carnauba wax, rice wax, wax, beeswax, montan wax, ozokerite, ceresin, paraffin wax, microcrystalline wax , Petrolatum, Fischer-Tropsch wax, polyethylene wax, ethylene / propylene copolymer and other waxes; palm oil, palm oil, palm kernel oil, safflower oil, olive oil, castor oil, avocado oil, sesame oil, tea oil, evening primrose oil, Wheat germ oil, macadamia nut oil, hazelnut oil, kukui nut oil, rosehip oil, meadow foam oil, persic oil, tea tree oil, mint oil, corn oil, rapeseed oil, sunflower oil, wheat germ oil, linseed oil, cottonseed oil, soybean oil Vegetable oils such as peanut oil, rice bran oil, cacao butter, shea butter, hydrogenated palm oil, hydrogenated castor oil, jojoba oil, hydrogenated jojoba oil; beef tallow, milk fat, horse fat, egg yolk oil, mink oil, turtle Animal fats and oils such as oil; animal oils such as whale wax, lanolin and orange luffy oil Liquid lanolin, reduced lanolin, adsorption purified lanolin, lanolin acetate, acetic acid liquid lanolin, hydroxy lanolin, polyoxyethylene lanolin, lanolin fatty acid, hard lanolin fatty acid, lanolin alcohol, lanolin alcohol acetate, acetic acid (cetyl lanolyl) ester, etc. Lanolins: phospholipids such as lecithin, phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, phosphatidylglycerol, phosphatidylinositol, sphingomyelin, phosphatidic acid, lysolecithin, etc .; hydrogenated soybean phospholipid, partially hydrogenated soybean phospholipid , Phospholipid derivatives such as hydrogenated egg yolk phospholipid, partially hydrogenated egg yolk phospholipid; cholesterol, dihydrocholesterol, lanosterol, dihi Sterols such as loranosterol, phytosterol, cholic acid; sapogenins; saponins; cholesteryl acetate, cholesteryl nonanoate, cholesteryl stearate, cholesteryl isostearate, cholesteryl oleate, di-N-lauroyl-L-glutamate (cholesteryl / behenyl / Octyldodecyl), N-lauroyl-L-glutamate di (cholesteryl / octyldodecyl), N-lauroyl-L-glutamate di (phytosteryl / behenyl / octyldodecyl), N-lauroyl-L-glutamate di (phytosteryl / octyldodecyl) Acyl sarcosine alkyl esters such as N-lauroyl sarcosine isopropyl, cholesteryl 12-hydroxystearate, macadamia nut oil fatty acid cholesteryl, Steroid esters such as macadamia nut oil fatty acid phytosteryl, isostearate phytosteryl, soft lanolin fatty acid cholesteryl, hard lanolin fatty acid cholesteryl, long chain branched fatty acid cholesteryl, long chain α-hydroxy fatty acid cholesteryl; phospholipid / cholesterol complex, phospholipid / phytosterol complex Lipid complexes such as octyldodecyl myristate, hexyldecyl myristate, octyldodecyl isostearate, cetyl palmitate, octyldodecyl palmitate, cetyl octanoate, hexyldecyl octanoate, isotridecyl isononanoate, isononanoyl isononanoate, isononanoic acid Octyl, isotridecyl isononanoate, isodecyl neopentanoate, isotridecyl neopentanoate, neopentanoic acid Stearyl, octyldodecyl neodecanoate, oleyl oleate, octyldodecyl oleate, octyldodecyl ricinoleate, lanolin fatty acid octyldodecyl, hexyldecyl dimethyloctanoate, octyldodecyl erucate, isostearic acid hydrogenated castor oil, ethyl oleate, avocado oil fatty acid Ethyl, isopropyl myristate, isopropyl palmitate, octyl palmitate, isopropyl isostearate, lanolin fatty acid isopropyl, diethyl sebacate, diisopropyl sebacate, dioctyl sebacate, diisopropyl adipate, dibutyloctyl sebacate, diisobutyl adipate, dioctyl succinate , Monoalcohol carboxylic acid esters such as triethyl citrate; cetyl lactate, dii malate Oxyacid esters such as sostearyl, monoisostearic acid hydrogenated castor oil; glyceryl trioctanoate, glyceryl trioleate, glyceryl triisostearate, glyceryl diisostearate, tri (caprylic acid / capric acid) glyceryl, tri (caprylic acid / caprin) Acid / myristic acid / stearic acid) glyceryl, hydrogenated rosin triglyceride (hydrogenated ester gum), rosin triglyceride (ester gum), glyceryl behenate, trimethylolpropane trioctanoate, trimethylolpropane triisostearate, dioctanoic acid Neopentyl glycol, neopentyl glycol dicaprate, 2-butyl-2-ethyl-1,3-propanediol dioctanoate, propylene glycol dioleate Pentaerythrityl tetraoctanoate, hydrogenated rosin pentaerythrityl, ditrimethylolpropane triethylhexanoate, ditrimethylolpropane (isostearic acid / sebacic acid), pentaerythrityl triethylhexanoate, (hydroxystearic acid / stearic acid / rosin acid) Dipentaerythrityl, diglyceryl diisostearate, polyglyceryl tetraisostearate, polyglyceryl-10 nonaisostearate, deca (erucic acid / isostearic acid / ricinoleic acid) polyglyceryl-8, (hexyldecanoic acid / sebacic acid) diglyceryl oligoester, glycol distearate ( Ethylene glycol distearate), 3-methyl-1,5-pentanediol dineopentanoate, 2, dineopentanoic acid 2, Polyhydric alcohol fatty acid esters such as diethyl-1,5-pentanediol; diisopropyl dimerlinoleate, diisostearyl dimerdilinoleate, dimerdilinoleate di (isostearyl / phytosteryl), dimerdilinoleic acid (phytosteryl) / Behenyl), dimer dilinoleic acid (phytosteryl / isostearyl / cetyl / stearyl / behenyl), dimer dilinoleic acid dimer dilinoleyl, diisostearic dimer dilinoleyl, dimer dilinoleyl hydrogenated rosin condensate, dimer dilinol Dimer acid or dimer diol derivative such as acid-hardened castor oil, hydroxyalkyl dimer linoleyl ether; coconut oil fatty acid monoethanolamide (cocamide MEA), coconut oil fatty acid diethanola Amide (cocamide DEA), lauric acid monoethanolamide (lauramide MEA), lauric acid diethanolamide (lauramide DEA), lauric acid monoisopropanolamide (lauramide MIPA), palmitic acid monoethanolamide (partamide MEA), palmitic acid diethanolamide ( Fatty acid alkanolamides such as partamide DEA), palm oil fatty acid methylethanolamide (cocamidomethyl MEA); dimethicone (dimethylpolysiloxane), highly polymerized dimethicone (highly polymerized dimethylpolysiloxane), cyclomethicone (cyclic dimethylsiloxane, decamethylcyclopenta Siloxane), phenyltrimethicone, diphenyldimethicone, phenyldimethicone, stearoxypropyldimethylamine, (aminoethylamino) (Ropyrumethicone / dimethicone) copolymer, dimethiconol, dimethiconol crosspolymer, silicone resin, silicone rubber, amino-modified silicone such as aminopropyl dimethicone and amodimethicone, cation-modified silicone, polyether-modified silicone such as dimethicone copolyol, polyglycerin-modified silicone, sugar Modified silicone, carboxylic acid modified silicone, phosphoric acid modified silicone, sulfuric acid modified silicone, alkyl modified silicone, fatty acid modified silicone, alkyl ether modified silicone, amino acid modified silicone, peptide modified silicone, fluorine modified silicone, cation modified and polyether modified silicone, Amino- and polyether-modified silicones, alkyl- and polyether-modified silicones, Silicones such as hexane-polyoxyalkylene copolymer; perfluorodecane, perfluorooctane, fluorine-based oils such as perfluoropolyether may be mentioned as preferred.

  As the humectant / feel improver, glycerin, 1,3-butylene glycol, propylene glycol, 3-methyl-1,3-butanediol, 1,3-propanediol, 2-methyl-1,3-propanediol, Polyols such as trimethylolpropane, pentaerythritol, hexylene glycol, diglycerin, polyglycerin, diethylene glycol, polyethylene glycol, dipropylene glycol, polypropylene glycol, ethylene glycol / propylene glycol copolymer and polymers thereof; diethylene glycol monoethyl ether (Ethoxydiglycol), ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, diethylene glycol dibutyl ether, etc. (Eicosandioic acid / tetradecandioic acid) water-soluble esters such as polyglyceryl-10 and tetradecandioic acid polyglyceryl-10; sugar alcohols such as sorbitol, xylitol, erythritol, mannitol, maltitol; glucose, fructose, galactose Mannose, threose, xylose, arabinose, fucose, ribose, deoxyribose, maltose, trehalose, lactose, raffinose, gluconic acid, glucuronic acid, cyclodextrins (α-, β-, γ-cyclodextrin, and maltosylation, Modified cyclodextrins such as hydroxyalkylation), β-glucan, chitin, chitosan, heparin and derivatives, pectin, arabinogalactan, dextrin, dextran, glycogen Sugars such as ethyl glucoside, glucosyl ethyl methacrylate polymer or copolymer, and derivatives thereof; hyaluronic acid, sodium hyaluronate; chondroitin sulfate sodium; mucoitin sulfate, caroline sulfate, kerato sulfate, dermatan sulfate; white jellyfish extract, white jellyfish Polysaccharides; Fucoidan; Tuberose polysaccharides, naturally derived polysaccharides; Organic acids such as citric acid, tartaric acid and lactic acid and salts thereof; Urea; 2-pyrrolidone-5-carboxylic acid and salts thereof such as sodium; Betaine (trimethylglycine) , Proline, hydroxyproline, arginine, lysine, serine, glycine, alanine, phenylalanine, tyrosine, β-alanine, threonine, glutamic acid, glutamine, asparagine, aspartic acid, cysteine, cystine, methio , Leucine, isoleucine, valine, tryptophan, histidine, taurine and other amino acids and salts thereof; collagen, fish-derived collagen, atelocollagen, gelatin, elastin, collagen-degrading peptide, hydrolyzed collagen, hydroxypropylammonium chloride-hydrolyzed collagen, elastin Degraded peptide, keratin degrading peptide, hydrolyzed keratin, conchiolin degrading peptide, hydrolyzed conchiolin, silk proteolytic peptide, hydrolyzed silk, lauroyl hydrolyzed silk sodium, soybean proteolytic peptide, wheat proteolytic peptide, hydrolyzed wheat protein, casein Protein peptides such as degraded peptides and acylated peptides and their derivatives; palmitoyl oligopeptide, palmitoyl pentapeptide, palmitoyl tetrapep Acylated peptides such as tide; silylated peptides; lactic acid bacteria culture solution, yeast extract, eggshell membrane protein, bovine submandibular gland mucin, hypotaurine, sesame lignan glycoside, glutathione, albumin, whey; choline chloride, phosphorylcholine; Animal and plant extract components such as placenta extract, aerostin, collagen, aloe extract, hamamelis water, loofah water, chamomile extract, licorice extract, comfrey extract, silk extract, Izayoi rose extract, yarrow extract, eucalyptus extract, and melilot extract Preferred are ceramides such as natural ceramides (types 1, 2, 3, 4, 5, 6), hydroxyceramide, pseudoceramide, glycosphingolipid, ceramide, and sugar-ceramide-containing extract.

Preferred examples of the surfactant include an anionic surfactant, a nonionic surfactant, a cationic surfactant, an amphoteric surfactant, and a polymer surfactant. There is no restriction | limiting in particular in HLB of surfactant, It can use from about 1 low thing to about 20 high thing, It is also preferable to combine a low thing and a high thing of HLB. Examples of preferable surfactants include fatty acid salts such as potassium laurate and potassium myristate; alkyl sulfates such as sodium lauryl sulfate, triethanolamine lauryl sulfate, and ammonium lauryl sulfate; laureth Polyoxyethylene alkyl sulfates such as sodium sulfate and laureth sulfate triethanolamine; cocoyl methyl taurine sodium, cocoyl methyl taurine potassium, lauroyl methyl taurine sodium, myristoyl methyl taurine sodium, lauroyl methyl alanine sodium, lauroyl sarcosine sodium, lauroyl sarcosine triethanol Acyl N-methyl amino acid salts such as amines and sodium methylalanine lauroylglutamate; Cocoyl Glue Acyl amino acid salts such as sodium minate, triethanolamine cocoyl glutamate, sodium lauroyl glutamate, sodium myristoyl glutamate, sodium stearoyl glutamate, ditriethanolamine palmitoyl aspartate, cocoylalanine triethanolamine; polyoxyethylene alkyl ethers such as sodium laureth acetate Acetic acid salt; Succinic acid ester salt such as sodium lauroyl monoethanolamide succinate; Fatty acid alkanolamide ether carboxylate; Acyl lactate; Polyoxyethylene fatty amine sulfate; Fatty acid alkanolamide sulfate; Hardened coconut oil fatty acid sodium glyceryl sulfate Fatty acid glyceride sulfate such as alkylbenzene polyoxyethylene sulfate; α-olefin Olefin sulfonates such as sodium sulfonate; alkylsulfosuccinates such as disodium lauryl sulfosuccinate and dioctyl sodium sulfosuccinate; disodium laureth sulfosuccinate, monolauroyl monoethanolamide polyoxyethylene sodium sulfosuccinate, lauryl polypropylene glycol sulfosuccinic acid Alkyl ether sulfosuccinates such as sodium; alkylbenzene sulfonates such as sodium tetradecylbenzenesulfonate and tetraethanolamine tetraethanol; alkylnaphthalenesulfonates; alkanesulfonates; α-sulfo fatty acid methyl ester salts; Acyl isethionate; alkyl glycidyl ether sulfonate; alkyl sulfoacetate; laurethrin Alkyl ether phosphates such as sodium, sodium dilaureth phosphate, sodium trilaureth phosphate, sodium monooles phosphate; alkyl phosphate salts such as potassium lauryl phosphate; sodium caseinate; alkyl aryl ether phosphate; fatty acid amide ether phosphorus Phospholipids such as phosphatidylglycerol, phosphatidylinositol, and phosphatidic acid; silicone anionic surfactants such as carboxylic acid-modified silicone, phosphate-modified silicone, and sulfate-modified silicone; and nonionic surfactants, laureth (Polyoxyethylene lauryl ether), ceteth (polyoxyethylene cetyl ether), steareth (polyoxyethylene stearyl ether), behenez (polyoxyethylene) Nbehenyl ethers), isosteares (polyoxyethylene isostearyl ethers), octyldecesses (polyoxyethylene octyldodecyl ethers) and other polyoxyethylene alkyl ethers with various polyoxyethylene addition numbers; polyoxyethylene alkylphenyl ethers; Polyoxyethylene hydrogenated castor oil, polyoxyethylene castor oil, polyoxyethylene hydrogenated castor oil monoisostearate, polyoxyethylene hydrogenated castor oil triisostearate, polyoxyethylene hydrogenated castor oil monopyroglutamic acid monoisostearate diester, poly Castor oil such as oxyethylene hydrogenated castor oil maleic acid and hydrogenated castor oil derivatives; polyoxyethylene phytosterol; polyoxyethylene cholesterol; polyoxy Polyoxyethylene lanolin; polyoxyethylene reduced lanolin; polyoxyethylene polyoxypropylene cetyl ether, polyoxyethylene polyoxypropylene 2-decyltetradecyl ether, polyoxyethylene polyoxypropylene monobutyl ether, polyoxyethylene lanolin; Oxyethylene / polyoxypropylene hydrogenated lanolin, polyoxyethylene / polyoxypropylene alkyl ethers such as polyoxyethylene / polyoxypropylene glycerin ether; polyoxyethylene / polyoxypropylene glycol; (poly) such as PPG-9 diglyceryl Glycerin polyoxypropylene glycol; glyceryl stearate, glyceryl isostearate, glyceryl palmitate, myristate group Glyceryl fatty acid partial esters such as ceryl, glyceryl oleate, glyceryl coconut fatty acid, mono-cotton oil fatty acid glycerin, glyceryl monoerucate, glyceryl sesquioleate, α, α'-oleic acid pyroglutamic acid glycerin, monostearic acid glycerin malic acid; Polyglyceryl stearate-2, 3, 4, 5, 6, 8, 10, polyglyceryl distearate-6, 10, polyglyceryl tristearate, polyglyceryl decastearate-10, polyglyceryl isostearate -2, 3, 4, 5, 6, 8, 10, diglycostyl diisostearate (diglyceryl diisostearate), 3, 10, polyglyceryl-2 triisostearate, polyglyceryl tetraisostearate Ril-2, polyglyceryl-10 decaisostearate, polyglyceryl-2 oleate, 3,4, 5,6, 8,8, dioleate polyglyceryl-6, trioleate polyglyceryl-2, dekaoleic acid Polyglyceryl fatty acid esters such as polyglyceryl-10; ethylene glycol monofatty acid esters such as ethylene glycol monostearate; propylene glycol monofatty acid esters such as propylene glycol monostearate; pentaerythritol partial fatty acid esters; sorbitol partial fatty acid esters; maltitol moieties Fatty acid ester; maltitol ether; sorbitan monooleate, sorbitan monoisostearate, sorbitan monolaurate, sorbitan monopalmitate, sorbitan monos Sorbitan fatty acid esters such as allate, sorbitan sesquioleate, sorbitan trioleate, diglycerol sorbitan penta-2-ethylhexylate, diglycerol sorbitan tetra-2-ethylhexylate; sucrose fatty acid ester, methyl glucoside fatty acid ester, trehalose undecylenate, etc. Partial derivatives of sugar derivatives; alkyl glucosides such as caprylyl glucoside; alkyl polyglycosides; lanolin alcohols; reduced lanolin; polyoxyethylene distearate, polyethylene glycol diisostearate, polyoxyethylene monooleate, polyoxyethylene di- Polyoxyethylene fatty acid mono- and diesters such as oleate; polyoxyethylene propylene glycol fatty acid ester; polyoxyethylene Polyoxyethylene glycerin fatty acid esters such as polyoxyethylene monooleate such as polyglycerin monostearate, polyoxyethylene glycerin monoisostearate, polyoxyethylene glycerin triisostearate; polyoxyethylene sorbitan monooleate, polyoxy Polyoxyethylene sorbitan fatty acid esters such as ethylene sorbitan monostearate, polyoxyethylene sorbitan monooleate, polyoxyethylene sorbitan tetraoleate; polyoxyethylene sorbitol monolaurate, polyoxyethylene sorbitol monooleate, polyoxyethylene sorbitol penta Polyoxyethylene sorbitol fatty acid esters such as oleate and polyoxyethylene sorbitol monostearate Polyoxyethylene methyl glucoside fatty acid ester; Polyoxyethylene alkyl ether fatty acid ester; Polyoxyethylene animal and vegetable oils such as polyoxyethylene sorbitol beeswax; Alkyl such as isostearyl glyceryl ether, chimyl alcohol, ceralkyl alcohol, batyl alcohol Glyceryl ethers; polyhydric alcohol alkyl ethers; polyoxyethylene alkylamines; tetrapolyoxyethylene / tetrapolyoxypropylene-ethylenediamine condensates; natural surfactants such as saponins and sophorolipids; polyoxyethylene fatty acid amides; coconut oil Fatty acid monoethanolamide (cocamide MEA), coconut oil fatty acid diethanolamide (cocamide DEA), lauric acid monoethanolamide (laura) De-MEA), lauric acid diethanolamide (lauramide DEA), lauric acid monoisopropanolamide (lauramide MIPA), palmitic acid monoethanolamide (partamid MEA), palmitic acid diethanolamide (partamide DEA), palm oil fatty acid methylethanolamide (cocamidomethyl) Fatty acid alkanolamides such as MEA); alkyldimethylamine oxides such as lauramine oxide, cocamamine oxide, stearamine oxide, and behenamine oxide; alkylethoxydimethylamine oxide; polyoxyethylene alkyl mercaptan; poly such as dimethicone copolyol Silicone such as ether-modified silicone, polysiloxane-oxyalkylene copolymer, polyglycerin-modified silicone, sugar-modified silicone Nonionic surfactants, etc .; for cationic surfactants, alkyltrimethylammonium chlorides such as behentrimonium chloride, steartrimonium chloride, cetrimonium chloride, lauryltrimonium chloride; alkyls such as stearyltrimonium bromide Trialkylammonium bromide; dialkyldimethylammonium chloride such as distearyldimonium chloride and dicocodimonium chloride; fatty acid amidoamines and salts thereof such as stearamidepropyldimethylamine and stearamideethyldiethylamine; alkyl ether amines such as stearoxypropyldimethylamine; Salt or quaternary salt thereof; ethyl sulfate long chain branched fatty acid (12-31) aminopropylethyldimethylammonium, ethyl lanolin sulfate Fatty acid amide-type quaternary ammonium salts such as aminopropylethyldimethylammonium fatty acid; polyoxyethylene alkylamine and its salts or quaternary salts; alkylamine salts; fatty acid amidoguanidinium salts; alkyl etheraminemonium salts; Benzalkonium salt; Pyridinium salt such as cetylpyridinium chloride; Imidazolinium salt; Alkylisoquinolinium salt; Dialkyl morpholinium salt; Polyamine fatty acid derivatives; Aminopropyl dimethicone and amodimethicone Silicone-based cationic surfactants such as amino-modified silicone, cation-modified silicone, cation-modified and polyether-modified silicone, amino-modified and polyether-modified silicone;
In amphoteric surfactants, N-alkyl-N, N-dimethylamino acid betaines such as lauryl betaine (lauryldimethylaminoacetic acid betaine); fatty acid amide alkyl-N, N-dimethylamino acids such as cocamidopropyl betaine and lauramidopropyl betaine Betaines; imidazoline-type betaines such as sodium cocoamphoacetate and sodium lauroamphoacetate; alkylsulfobetaines such as alkyldimethyltaurine; sulfate-type betaines such as alkyldimethylaminoethanol sulfate; phosphate-type betaines such as alkyldimethylaminoethanol phosphate; Sphingophospholipids such as phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, sphingomyelin, lysolecithin, hydrogenated soybean phospholipid, partially hydrogenated Phospholipids such as soybean phospholipid, hydrogenated egg yolk phospholipid, partially hydrogenated egg yolk phospholipid, and hydroxylated lecithin; silicone-based amphoteric surfactants; polymer surfactants such as polyvinyl alcohol, sodium alginate, starch derivatives, Preferred are tragacanth gum, acrylic acid / alkyl methacrylate copolymer; and various silicone surfactants.

  Polymers, thickeners and gelling agents include guar gum, locust bean gum, queens seed, carrageenan, galactan, arabic gum, tara gum, tamarind, far selelain, karaya gum, troarooi, cara gum, tragacanth gum, pectin, pectic acid and sodium Salt such as salt, salt such as alginic acid and sodium salt, mannan; starch such as rice, corn, potato, wheat; xanthan gum, dextran, succinoglucan, curdlan, hyaluronic acid and its salt, xanthan gum, pullulan, gellan gum, chitin , Chitosan, agar, gypsum extract, chondroitin sulfate, casein, collagen, gelatin, albumin; methylcellulose, ethylcellulose, hydroxyethylcellulose, hydroxypropi Cellulose, carboxymethylcellulose and its salts such as sodium, methylhydroxypropylcellulose, sodium cellulose sulfate, cellulose dialkyldimethylammonium sulfate, crystalline cellulose, cellulose powder such as cellulose powder; soluble starch, carboxymethyl starch, methylhydroxypropyl starch, Starch-based polymers such as methyl starch, starch derivatives such as hydroxypropyltrimonium chloride, octenyl succinate corn starch and aluminum; alginic acid derivatives such as sodium alginate and propylene glycol alginate; polyvinylpyridone (PVP), polyvinyl alcohol (PVA), Vinyl pydridone-vinyl alcohol copolymer, polyvinyl methyl ether Polyethylene glycol, polypropylene glycol, polyoxyethylene / polyoxypropylene copolymer; amphoteric methacrylic acid such as (methacryloyloxyethylcarboxybetaine / alkyl methacrylate) copolymer, (acrylates / stearyl acrylate / ethylamine methacrylate oxide) copolymer, etc. Ester copolymer; (Dimethicone / vinyl dimethicone) crosspolymer, (alkyl acrylate / diacetone acrylamide) copolymer, (alkyl acrylate / diacetone acrylamide) copolymer AMP; Polyvinyl acetate partial saponification product, maleic acid copolymer; Vinylpyrrolidone / dialkylaminoalkyl methacrylate copolymer; acrylic resin alkanolamine; polyester, water-dispersible polyester; Kurylamide; Polyacrylic acid ester copolymer such as polyethyl acrylate, carboxyvinyl polymer, polyacrylic acid and its sodium salt, acrylic acid / methacrylic acid ester copolymer; acrylic acid / alkyl methacrylate Polymer: Cationic cellulose such as polyquaternium-10, diallyldimethylammonium chloride / acrylamide copolymer such as polyquaternium-7, acrylic acid / diallyldimethylammonium chloride copolymer such as polyquaternium-22, and acrylic acid such as polyquaternium-39・ Diallyldimethylammonium chloride / acrylamide copolymer, acrylic acid / cationized methacrylic acid ester copolymer, acrylic acid / cationized methacrylic acid amide copolymer, polyquaternium Acrylic acid / methyl acrylate / methacrylamidopropyltrimethylammonium chloride copolymer such as 47, methacrylic acid choline ester polymer; cationized polysaccharides such as cationized oligosaccharide, cationized dextran, guar hydroxypropyltrimonium chloride; Polyethyleneimine; Cationic polymer; Polymer of 2-methacryloyloxyethyl phosphorylcholine such as polyquaternium-51 and copolymer with butyl methacrylate copolymer; Acrylic resin emulsion, polyethyl acrylate emulsion, polyacrylalkyl ester emulsion, Polymer emulsions such as polyvinyl acetate resin emulsion, natural rubber latex, synthetic latex; nitrocellulose; polyurethanes and various copolymers; various silicones Various silicone-based copolymers such as acrylic-silicone graft copolymers; various fluoropolymers; 12-hydroxystearic acid and its salts; dextrin fatty acid esters such as dextrin palmitate and dextrin myristate; silicic anhydride, Smoke-like silica (ultrafine silicic anhydride), aluminum magnesium silicate, magnesium magnesium silicate, metal soap, dialkyl phosphate metal salt, bentonite, hectorite, organically modified clay mineral, sucrose fatty acid ester, fructooligosaccharide fatty acid ester It is mentioned as preferable.

  Solvents and propellants include ethanol, 2-propanol (isopropyl alcohol), butanol, isobutyl alcohol and other lower alcohols; propylene glycol, 1,3-butylene glycol, diethylene glycol, dipropylene glycol, isopentyl diol and other glycols Diethylene glycol monoethyl ether (ethoxydiglycol), ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, triethylene glycol monoethyl ether, diethylene glycol diethyl ether, diethylene glycol dibutyl ether, propylene glycol monoethyl ether, dipropylene glycol monoethyl ether Glycol ethers such as ethylene glycol monoethyl ether Glycol ether esters such as acetate, diethylene glycol monoethyl ether acetate, propylene glycol monoethyl ether acetate; Glycol esters such as diethoxyethyl succinate, ethylene glycol disuccinate; benzyl alcohol, benzyloxyethanol, propylene carbonate, dialkyl carbonate , Acetone, ethyl acetate, N-methylpyrrolidone; toluene; fluorocarbon, next-generation flon; propellants such as LPG, dimethyl ether, carbon dioxide, and the like are preferable.

  Antioxidants include tocopherol derivatives such as tocopherol (vitamin E) and tocopherol acetate; BHT, BHA; gallic acid derivatives such as propyl gallate; vitamin C (ascorbic acid) and / or derivatives thereof; erythorbic acid and derivatives thereof; Preferred are sulfites such as sodium sulfite; bisulfites such as sodium bisulfite; thiosulfates such as sodium thiosulfate; metabisulfites; thiotaurine, hypotaurine; thioglycerol, thiourea, thioglycolic acid, cysteine hydrochloride As mentioned. Preferred examples of the reducing agent include thioglycolic acid, cysteine, cysteamine and the like. Preferred examples of the oxidizing agent include aqueous hydrogen peroxide, ammonium persulfate, sodium bromate, and percarbonate.

  Preservatives and antibacterial agents include hydroxybenzoic acid such as methylparaben, ethylparaben, propylparaben, and butylparaben and salts or esters thereof; salicylic acid; sodium benzoate; phenoxyethanol; 1,2-pentanediol, 1,2-hexane 1,2-diols such as diols; isothiazolinone derivatives such as methylchloroisothiazolinone and methylisothiazolinone; imidazolinium urea; dehydroacetic acid and its salts; phenols; halogenated bisphenols such as triclosan, acid amides , Quaternary ammonium salts; trichlorocarbanide, zinc pyrithione, benzalkonium chloride, benzethonium chloride, sorbic acid, chlorhexidine, chlorhexidine gluconate, halocarban, hexachlorophene, Kichioru; phenol, isopropyl phenol, cresol, thymol, p-chlorophenol, phenylphenol, other phenols such as phenylphenol sodium; phenylethyl alcohol, photosensitive Motorui, be mentioned as antibacterial zeolite, silver ion. Examples of chelating agents include edetate (ethylenediaminetetraacetate) such as EDTA, EDTA2Na, EDTA3Na, and EDTA4Na; hydroxyethylethylenediaminetriacetate such as HEDTA3Na; pentetate (diethylenetriaminepentaacetate); phytic acid; Phosphonic acid and its sodium salt; sodium oxalate; polypolyamino acids such as polyaspartic acid and polyglutamic acid; sodium polyphosphate, sodium metaphosphate, phosphoric acid; sodium citrate, citric acid, alanine, dihydroxyethylglycine Gluconic acid, ascorbic acid, succinic acid, and tartaric acid are preferable. pH adjusters / acids / alkalis include citric acid, sodium citrate, lactic acid, sodium lactate, glycolic acid, succinic acid, acetic acid, sodium acetate, malic acid, tartaric acid, fumaric acid, phosphoric acid, hydrochloric acid, sulfuric acid, monoethanol Amine, diethanolamine, triethanolamine, isopropanolamine, triisopropanolamine, 2-amino-2-methyl-1,3-propanediol, 2-amino-2-hydroxymethyl-1,3-propanediol, arginine, hydroxylation Sodium, potassium hydroxide, aqueous ammonia, guanidine carbonate, and ammonium carbonate are preferable.

  Examples of powders include mica, talc, kaolin, sericite, montmorillonite, kaolinite, mica, muscovite, phlogopite, synthetic mica, red mica, biotite, permiculite, magnesium carbonate, calcium carbonate, aluminum silicate, silica Barium acid, calcium silicate, magnesium silicate, strontium silicate, metal tungstate, magnesium, zeolite, barium sulfate, calcined calcium sulfate, calcium phosphate, fluorine apatite, hydroxyapatite, ceramic powder, bentonite, smectite, clay, mud, Metal soap (e.g., zinc myristate, calcium palmitate, aluminum stearate), calcium carbonate, bengara, yellow iron oxide, black iron oxide, ultramarine, bitumen, carbon black, titanium oxide, fine particles and ultrafine Titanium oxide, zinc oxide, fine and ultrafine zinc oxide, alumina, silica, fumed silica (ultrafine silica), titanium mica, fish scale foil, boron nitride, photochromic pigment, synthetic fluorophlogopite, fine particle composite powder Body, gold, aluminum, etc., various sizes and shapes of inorganic powders, and these are treated with various surface treatment agents such as hydrogen silicone, cyclic hydrogen silicone, or other silane or titanium coupling agents Inorganic powders such as hydrophobized or hydrophilized powders; starch, cellulose, nylon powder, polyethylene powder, polymethyl methacrylate powder, polystyrene powder, copolymer resin powder of styrene and acrylic acid, polyester powder, Benzoguanamine resin powder, polyethylene terephthalate, polymethyl Organic powders and surface-treated powders of various sizes and shapes, such as methacrylate powder, polyethylene terephthalate / aluminum / epoxy powder, urethane powder, silicone powder, Teflon (registered trademark) powder, organic-inorganic composite powder Is preferable. Inorganic salts include sodium chloride-containing salts such as salt, common salt, rock salt, sea salt, natural salt; potassium chloride, aluminum chloride, calcium chloride, magnesium chloride, bittern, zinc chloride, ammonium chloride; sodium sulfate, aluminum sulfate, Aluminum sulfate / potassium sulfate (alum), aluminum sulfate / ammonium sulfate, barium sulfate, calcium sulfate, potassium sulfate, magnesium sulfate, zinc sulfate, iron sulfate, copper sulfate; sodium phosphates such as 1Na, 2Na and 3Na phosphates, phosphoric acid Potassium, calcium phosphates and magnesium phosphates are preferred.

Examples of ultraviolet absorbers include paraaminobenzoic acid, paraaminobenzoic acid monoglycerin ester, N, N-dipropoxyparaaminobenzoic acid ethyl ester, N, N-diethoxyparaaminobenzoic acid ethyl ester, and N, N-dimethylparaaminobenzoic acid ethyl ester. Benzoic acid-based ultraviolet absorbers such as esters, N, N-dimethylparaaminobenzoic acid butyl ester, N, N-dimethylparaaminobenzoic acid ethyl ester; Anthranilic acid-based ultraviolet absorbers such as homomenthyl-N-acetylanthranilate; Salicylic acid And salicylic acid-based purple such as sodium salt, amyl salicylate, menthyl salicylate, homomenthyl salicylate, octyl salicylate, phenyl salicylate, benzyl salicylate, p-isopropanol phenyl salicylate Line absorber: Octyl cinnamate, ethyl-4-isopropyl cinnamate, methyl-2,5-diisopropyl cinnamate, ethyl-2,4-diisopropyl cinnamate, methyl-2,4-diisopropyl cinnamate, propyl-p- Methoxycinnamate, isopropyl-p-methoxycinnamate, isoamyl-p-methoxycinnamate, 2-ethylhexyl p-methoxycinnamate (octyl paramethoxycinnamate), 2-ethoxyethyl-p-methoxycinnamate (sinoxate), Cyclohexyl-p-methoxycinnamate, ethyl-α-cyano-β-phenylcinnamate, 2-ethylhexyl α-cyano-β-phenylcinnamate (octocrine), glyceryl mono-2-ethylhexanoyl-diparamethoxy Nameto, cinnamic acid UV absorbers such as ferulic acid and its derivatives; 2,4-dihydroxybenzophenone, 2,2'-
Dihydroxy-4-methoxybenzophenone, 2,2′-dihydroxy-4,4′-dimethoxybenzophenone, 2,2 ′, 4,4′-tetrahydroxybenzophenone, 2-hydroxy-4-
Methoxybenzophenone (oxybenzone-3), 2-hydroxy-4-methoxy-4'-methylbenzophenone, 2-hydroxy-4-methoxybenzophenone-5-sulfonate, 4-phenylbenzophenone, 2-ethylhexyl-4'-phenyl -Benzophenone ultraviolet absorbers such as benzophenone-2-carboxylate, 2-hydroxy-4-n-octoxybenzophenone, 4-hydroxy-3-carboxybenzophenone; 3- (4'-methylbenzylidene) -d, l- Camphor, 3-benzylidene-d, l-camphor; 2-phenyl-5-methylbenzoxazole; 2,2'-hydroxy-5-methylphenylbenzotriazole; 2- (2'-hydroxy-5'-t- Octylphenyl) benzotriazole; 2- (2′-H Dioxy-5'-methylphenylbenzotriazole;dibenzalazine;dianisoylmethane; 5- (3,3-dimethyl-2-norbornylidene) -3-pentan-2-one; di- such as 4-t-butylmethoxydibenzoylmethane Benzoylmethane derivatives; octyl triazone; urocanic acid derivatives such as urocanic acid and ethyl urocanate; 2- (2′-hydroxy-5′-methylphenyl) benzotriazole, 1- (3,4-dimethoxyphenyl) -4, Hydantoin derivatives such as 4-dimethyl-1,3-pentanedione, dimethoxybenzylidenedioxoimidazolidinepropionate 2-ethylhexyl, phenylbenzimidazolazole sulfonic acid, terephthalylidene dicamphulsulfonic acid, drometrizol trisiloxane, anthranyl Methyl, rutin and its derivatives, oryzanol and derivatives thereof as preferred.

  Examples of whitening agents include hydroquinone glycosides such as arbutin and α-arbutin and esters thereof; ascorbic acid phosphate salts such as ascorbic acid, sodium ascorbate phosphate and magnesium ascorbate phosphate, ascorbic acid Ascorbic acid fatty acid esters such as tetraisopalmitic acid ester, ascorbic acid alkyl ethers such as ascorbic acid ethyl ether, ascorbic acid glucosides such as ascorbic acid-2-glucoside and fatty acid esters thereof, ascorbic acid sulfate ester, tocopheryl ascorbyl phosphate Ascorbic acid derivatives such as kojic acid, ellagic acid, tranexamic acid and its derivatives, ferulic acid and its derivatives, placenta extract, glutathione, oryzanol, butylreso Shinoru, oil soluble Kamomiraekisu oil soluble licorice extract, Nishikawa willow extract, be mentioned as saxifrage extract, and the like plant extracts are preferred.

  Vitamins and their derivatives include vitamin A such as retinol, retinol acetate, retinol palmitate; thiamine hydrochloride, thiamine sulfate, riboflavin, riboflavin acetate, pyridoxine hydrochloride, pyridoxine dioctanoate, pyridoxine dipalmitate, Flavin adenine dinucleotide, cyanocobalamin, folic acid, nicotinic acid such as nicotinic acid amide / benzyl nicotinate, vitamin B group such as choline; vitamin C such as ascorbic acid and its sodium salt; vitamin D; α, Vitamin Es such as β, γ, δ-tocopherol; other vitamins such as pantothenic acid and biotin; ascorbic acid phosphates such as ascorbic acid phosphate sodium salt and ascorbic acid phosphate magnesium salt; Ascorbic acid fatty acid esters such as corobic acid tetraisopalmitic acid ester, ascorbyl stearate, ascorbyl palmitate and ascorbyl dipalmitate, ascorbic acid alkyl ether such as ascorbic acid ethyl ether, ascorbic acid glucoside such as ascorbic acid-2-glucoside and Ascorbic acid derivatives such as fatty acid esters and tocopheryl phosphate ascorbyl; vitamin derivatives such as tocopherol nicotinate, tocopherol acetate, tocopherol acetate, tocopherol linoleate, tocopherol phosphate, tocopherol phosphate etc., tocotrienol, and other various vitamin derivatives Is preferable.

  Anti-inflammatory and anti-inflammatory agents include glycyrrhizic acid and its derivatives, glycyrrhetinic acid derivatives, salicylic acid derivatives, hinokitiol, guaiazulene, allantoin, indomethacin, zinc oxide, hydrocortisone acetate, prednisone, diphedramine hydrochloride, chlorpheniramine maleate; peach leaf extract A plant extract such as a koji leaf extract is preferable. Plant growth and tinctures such as assembly extract, red pepper tincture, ginger tincture, ginger extract, cantalis tincture; capsaicin, nonyl acid valenylamide, gingeron, ictamol, tannic acid Borneol, cyclandelate, cinnarizine, trazoline, acetylcholine, verapamil, cephalanthin, γ-oryzanol, cephalanthin, vitamin E and nicotinic acid tocopherol, acetic acid tocopherol and other derivatives, γ-oryzanol, nicotinic acid, nicotinic acid amide, nicotinic acid benzyl Derivatives such as ester, inositol hexanicotinate, nicotine alcohol, allantoin, photosensitizer 301, photosensitizer 401, capronium chloride, pentadecanoic acid monoglyceride, Preferable examples include flavonol derivatives, stigmasterol or stigmasteranol, its glycosides, and minoxidil. Preferred hormones include estradiol, estrone, ethinyl estradiol, cortisone, hydrocortisone, prednisone and the like. Other remedies such as anti-wrinkle agents, anti-aging agents, squeeze agents, cooling sensations, warming sensation agents, wound healing promoters, irritation relievers, analgesics, cell activators include retinols, retinoic acids, retinoin Acid tocopheryl; derivatives such as lactic acid, glycolic acid, gluconic acid, fruit acid, salicylic acid and glycosides / esterified products thereof, α- or such as hydroxycapric acid, long chain α-hydroxy fatty acid, long chain α-hydroxy fatty acid cholesteryl β-hydroxy acids and derivatives thereof; γ-aminobutyric acid, γ-amino-β-hydroxybutyric acid; carnitine; carnosine; creatine; ceramides, sphingosines; caffeine, xanthine and the like; and coenzyme Q10, carotene, lycopene , Astaxanthin, lutein, α-lipoic acid, platinum nanocolloid, fullerenes, etc. Antioxidant / active oxygen scavengers; catechins; flavones such as quercetin; isoflavones; gallic acid and ester sugar derivatives; polyphenols such as tannin, sesamin, protoanthocyanidin, chlorogenic acid, apple polyphenol; rutin and glycosides, etc. Derivatives of hesperidin and glycosides; lignan glycosides; licorice extract-related substances such as grabrizine, glabrene, liquiritin, and isoliquiritin; lactoferrin; shogaol, gingerol; fragrance substances such as menthol, camphor, cedrol, and derivatives thereof Preferred examples include capsaicin, vanillin and the like and derivatives; insect repellents such as diethyltoluamide; and complexes of physiologically active substances and cyclodextrins.

  Plant / animal / microbe extracts include iris extract, ashitaba extract, asunalo extract, asparagus extract, avocado extract, achacha extract, almond extract, altea extract, arnica extract, aloe extract, apricot extract, apricot kernel extract, ginkgo biloba extract , Incheon extract, Fennel extract, Turmeric extract, Oolong tea extract, Peony extract, Ages extract, Echinacea leaf extract, Enmeo extract, Ogon extract, Oat extract, Auren extract, Barley extract, Panax ginseng extract, Hypericum extract, Odori extract , Dutch mustard extract, orange extract, dried sea water, seaweed extract, oyster leaf extract, oyster extract, hydrolyzed elastin, hydrolyzed wheat powder, hydrolysis Luc, Cascon extract, Chamomile extract, Oil-soluble chamomile extract, Carrot extract, Kawara mugi extract, Oat extract, Calcade extract, Licorice extract, Oil-soluble Licorice extract, Kiwi extract, Kiou extract, Cyprid extract, Quina extract, Cucumber extract, Kiri leaf extract, Guanosine, guava extract, cucumber extract, gardenia extract, kumazasa extract, clara extract, walnut extract, chestnut extract, grapefruit extract, clematis extract, black rice extract, brown sugar extract, black vinegar, chlorella extract, mulberry extract, gentian extract, Gentian pepper extract, tea Extract, yeast extract, kokuboku extract, coffee extract, burdock extract, rice extract, rice fermented extract, rice bran fermented extract, rice germ oil, comfrey extract, Lagen, Cowberry extract, Saishin extract, Psycho extract, Saitai extract, Saffron extract, Salvia extract, Salmon extract, Sasa extract, Hawthorn extract, Sansha extract, Salamander extract, Shiitake extract, Giant extract, Shikon extract, Perilla extract, Linden extract, Shimosukeso Extract, jatoba extract, peonies extract, ginger cucumber extract, ginger root extract, white birch extract, white jellyfish extract, horsetail extract, stevia extract, stevia fermented product, west river willow extract, horse chestnut extract, hawthorn extract, elderberry extract, yarrow extract , Mint extract, sage extract, mallow extract, nematode extract, essence extract, Sakuhakuhi extract, Diou extract, Dai Extract, peanut extract, thyme extract, dandelion extract, lichen extract, tea extract, clove extract, chigaya extract, chimpi extract, tea tree oil, tea tea extract, red pepper extract, red snapper extract, red snapper extract, red spruce extract, red spruce extract, tomato Extract, natto extract, carrot extract, garlic extract, wild rose extract, hibiscus extract, bacmond extract, lotus extract, parsley extract, birch extract, honey, hamamelis extract, parietalia extract, hyacinth extract, bisabolol, cypress extract, bifidobacteria extract, Loquat extract, dandelion extract, burdock extract, bukkuri extract, butcher bloom extract, grape extract, grape seed extract, propolis, loofah extract, Safflower extract, peppermint extract, body extract, button extract, hop extract, squid extract, pine extract, maroonnier extract, mizubasho extract, mukuroji extract, melissa extract, mozuku extract, peach extract, cornflower extract, eucalyptus extract, yukinoshita extract, yuzu extract, lily extract, Yokuinin extract, mugwort extract, lavender extract, green tea extract, eggshell membrane extract, apple extract, rooibos tea extract, litchi extract, lettuce extract, lemon extract, forsythia extract, forsythia extract, rose extract, rosemary extract, roman chamomile extract, royal jelly Extracts such as an extract and a bitumen extract are preferred.

  Examples of the antipruritic agent include diphenhydramine hydrochloride, chlorpheniramine maleate, camphor, substance-P inhibitor, and the like. Examples of the exfoliating / dissolving agent include salicylic acid, sulfur, resorcin, selenium sulfide, pyridoxine and the like. Examples of the antiperspirant include chlorohydroxyaluminum, aluminum chloride, zinc oxide, and zinc paraphenol sulfonate. Examples of the refreshing agent include menthol and methyl salicylate. Examples of the astringent include citric acid, tartaric acid, lactic acid, aluminum sulfate / potassium sulfate, and tannic acid. Examples of enzymes include superoxide dismutase, catalase, lysozyme chloride, lipase, papain, pancreatin, protease, and the like. Preferred nucleic acids include ribonucleic acid and salts thereof, deoxyribonucleic acid and salts thereof, and adenosine triphosphate disodium.

  As perfumes, acetyl cedrene, amylcinnamaldehyde, allyl amyl glycolate, β-ionone, iso-Esuper, isobutyl quinoline, Iris oil, Iron, indole, ylang ylang oil, undecanal, undecenal, γ-undecalactone, Estragole, eugenol, oak moss, opoponax resinoid, orange oil, eugenol, auranthiol, galac solid, carvacrol, L-carvone, camphor, cannon, carrot seed oil, clove oil, methyl cinnamate, geraniol, geranyl nitrile , Isobornyl acetate, geranyl acetate, dimethylbenzyl carvinyl acetate, styrylyl acetate, cedolyl acetate, terpinel acetate, pt-butylcyclohexyl acetate, vetiberyl acetate, benzyl acetate, vinegar Linalyl, isopentyl salicylate, benzyl salicylate, sandalwood oil, santalol, cyclamenaldehyde, cyclopentadecanolide, methyl dihydrojasmonate, dihydromilsenol, jasmine absolute, jasmine lactone, cis-jasmon, citral, citronenol, citronellal, Cinnamon bark oil, 1,8-cineole, cinnamaldehyde, stylax resinoid, cedarwood oil, cedrene, cedrol, celery seed oil, thyme oil, damascon, damacenone, thymol, tuberose absolute, decanal, decalactone, terpineol, γ-terpinene, Tripral, Nellore, Nonanal, 2,6-Nonadienol, Nonalactone, Patchouli alcohol, Vanilla absolute , Vanillin, basil oil, patchouli oil, hydroxycitronellal, α-pinene, piperitone, phenethyl alcohol, phenylacetaldehyde, petitglen oil, hexylcinnamaldehyde, cis-3-hexenol, peruvian valsum, vetiver oil, vetiverol, peppermint oil, Pepper oil, heliotropin, bergamot oil, benzyl benzoate, borneol, milresinoid, musk ketone, methylnonylacetaldehyde, γ-methylyonone, menthol, L-menthol, L-menthol, eucalyptus oil, β-yonone, lime oil, lavender oil, Synthetic and natural fragrances such as D-limonene, linalool, rilal, rireal, lemon oil, rose absolute, rose oxide, rose oil, rosemary oil, various essential oils, and various blended fragrances It is mentioned as preferred.

As pigments / colorants / dyes / pigments, brown 201, black 401, purple 201, purple 401, blue 1, blue 2, blue 201, blue 202, blue 203, blue 204 , Blue 205, Blue 403, Blue 404, Green 201, Green 202, Green 204, Green 205, Green 3, Green 401, Green 402, Red 102, Red 104-1 , Red 105-1, Red 106, Red 2, Red 201, Red 202, Red 203, Red 204, Red 205, Red 206, Red 207, Red 208, Red 213 Red 214, Red 215, Red 218, Red 219, Red 220, Red 221, Red 223, Red 225, Red 226, Red 227, Red 228, Red 230 No. 1, Red 230-2, Red 231, Red 232, Red 3, Red 401, Red 404, Red 405, Red 501, Red 502, Red 503, Red 504, Red 505, red 506, orange 201, orange 203, orange 204, orange 205, orange 206, orange 207, orange 401, orange 402, orange 403, yellow 201, yellow 202- No. 1, yellow 202-2, yellow 203, yellow 204, yellow 205, yellow 4, yellow 401, yellow 402, yellow 403-1, yellow 404, yellow 405, yellow 406 Legal dyes such as Yellow No. 407 and Yellow No. 5; Other acidic dyes such as Acid Red 14; Arianor Sienna Brown, Arianor Madder Red, Arianor
Basic dyes such as Steel Blue and Arianor Straw Yellow; HC Yellow 2, HC Yellow 5, HC Red 3, 4-hydoxypropylamino-3-nitrophenol, N, N'-bis (2-hydroxyethyl) -2-nitro-p-
Nitro dyes such as phenylenediamine, HC Blue 2 and Basic Blue 26; disperse dyes; inorganic white pigments such as titanium dioxide and zinc oxide; inorganic red pigments such as iron oxide (Bengara) and iron titanate; and γ-iron oxide Inorganic brown pigments; inorganic yellow pigments such as yellow iron oxide and ocher; inorganic black pigments such as black iron oxide and low-order titanium oxide; inorganic purple pigments such as mango violet and cobalt violet; chromium oxide and chromium hydroxide Inorganic green pigments such as cobalt titanate; inorganic blue pigments such as ultramarine and bitumen; titanium oxide coated mica, titanium oxide coated bismuth oxychloride, titanium oxide coated talc, colored titanium oxide coated mica, bismuth oxychloride, fish scale foil Pearl powder such as aluminum powder, copper powder, metal powder pigment such as gold; surface treatment inorganic and metal powder pigment; red 01, Red 202, Red 204, Red 205, Red 220, Red 226, Red 228, Red 405, Orange 203, Orange 204, Yellow 205, Yellow 401, Blue 404 Red No. 3, Red No. 104, Red No. 106, Red No. 227, Red No. 230, Red No. 401, Red No. 505, Orange No. 205, Yellow No. 4, Yellow No. 5, Yellow No. 202, Yellow No. 203, Green Organic pigments such as zirconium, barium or aluminum lakes such as No. 3 and Blue No. 1; surface-treated organic pigments; anthraquinones such as astaxanthin and alizarin, anthocyanidins, β-carotene, catenal, capsanthin, chalcone, calsamine, quercetin, crocin, Naphthoquinones such as chlorophyll, curcumin, cochineal, shikonin, bixin, flavo Natural pigments and dyes such as amines, betacyanidine, henna, hemoglobin, lycopene, riboflavin, rutin; p-phenylenediamine, toluene-2,5-diamine, o-, m-, or p-aminophenol, m-phenylene Oxidative dye intermediates and couplers such as diamine, 5-amino-2-methylphenol, resorcin, 1-naphthol, 2,6-diaminopyridine and their salts; auto-oxidizing dyes such as indoline; Can be mentioned.

  Preferred examples of water include normal water, purified water, hard water, soft water, natural water, deep sea water, electrolytic alkaline ionized water, electrolytic acidic ionized water, ionic water, and clustered water.

  In addition to these, cosmetic raw material standards, blending ingredient standard by cosmetic varieties, Japan Cosmetic Industry Association ingredient display name list, INCI dictionary (The International Cosmetic Ingredient Dictionary and Handbook), quasi-drug raw material standards, Japanese pharmacopoeia, pharmaceutical additives Ingredients listed in standards, official food additives, etc., and Japanese and foreign patent publications and patent publications (including publications and republications) in which the international patent classification IPC belongs to the classification of A61K7 and A61K8 It is possible to contain known cosmetic ingredients, pharmaceutical ingredients, food ingredients, etc., such as the ingredients described, in known combinations, blending ratios and blending amounts.

  Examples of the cosmetic / skin external preparation of the present invention include skin external preparations such as hair cosmetics, basic cosmetics, makeup cosmetics, aromatic cosmetics, body cosmetics, and ointments. The cosmetic / skin external preparation of the present invention can be produced according to a usual method.

  The types of cosmetics and external preparations for skin according to the present invention will be described in more detail. Examples of hair cosmetics include oil shampoos, cream shampoos, conditioning shampoos, dandruff shampoos, hair color shampoos, rinse-integrated shampoos and the like. Rinsing, treatment, hair pack, hair foam, hair mousse, hair spray, hair mist, hair wax, hair gel, water grease, set lotion, color lotion, hair tonic, hair liquid, pomade, tic, hair cream, hair blow, split hair coat , Hair oil, permanent wave agent, straight permanent agent, oxidative hair dye, hair bleach, hair color pre-treatment, hair color after treatment, perm pre-treatment, perm after Treatments, hair manicure, and as hair growth agents are preferred.

  Basic cosmetics include soft lotion, astringent lotion, cleansing lotion, multi-layer lotion, etc .; emollient lotion, moisture lotion, milky lotion, nourishing lotion, nourishing milk, skin moisture, moisturizer -Emulsions such as emulsion, massage lotion, cleansing lotion, protect emulsion, sun protect, sun protector, UV care milk, sunscreen, makeup lotion, horny smoother, elbow lotion, hand lotion, body lotion; emollient cream, nutritional cream, nari Thing cream, burnishing cream, moisture cream, night cream, massage cream, cleansing cream, makeup cream, base cream Cream, sun makeup cream, suntan cream, hair removal cream, deodorant cream, shaving cream, keratin softening cream, etc .; gel such as moisture gel; essence such as moisturizing essence, whitening essence, UV protection essence; liposome Liposome cosmetics such as beauty essence and liposome lotion; Peel-off packs, powder packs, washing packs, oil packs, cleansing masks and other packs and masks; cleansing foams, cleansing creams, cleansing milks, cleansing lotions, cleansing gels, cleansing oils , Cleansing mask, washing powder, face washing powder, etc .; cosmetic soap, transparent soap, medicated soap, liquid soap, shaving soap, synthetic cosmetic soap Soap can be mentioned as preferred.

  Examples of makeup cosmetics that may be preferably used include white powder, dusts, foundations, lipsticks, lip gloss, blushers, eyeliner, mascara, eye shadow, eyebrow, eyebrow, nail enamel, enamel remover, and nail treatment.

  Preferred examples of the aromatic cosmetics include perfume, perfume, parfum, eau de parfum, eau de toilette, eau de cologne, perfumes, fragrance powder, perfume soap, body lotion and bath oil.

  Body cosmetics such as body shampoos; deodorant lotions, deodorant powders, deodorant sprays, deodorant sticks and other deodorant cosmetics; decoloring agents, hair removal / hair removal agents; bathing agents; insect repellents A repeller is preferred.

  Moreover, as a skin external preparation, it can be used with dosage forms, such as an ointment, a patch, a lotion agent, a liniment agent, and a liquid coating agent. It can also be used as an oral cosmetic such as toothpaste and mouthwash.

  As the dosage form of the cosmetic or external preparation for skin of the present invention, emulsification such as oil-in-water (O / W) type, water-in-oil (W / O) type, W / O / W type, O / W / O type, etc. Type cosmetics, oily cosmetics, solid cosmetics, liquid cosmetics, paste cosmetics, stick cosmetics, volatile oil cosmetics, powder cosmetics, jelly cosmetics, gel cosmetics, pastes Preferred examples include cosmetics, emulsified polymer cosmetics, sheet cosmetics, mist cosmetics, and spray cosmetics.

  EXAMPLES Hereinafter, although this invention is demonstrated in detail using an Example, this invention is not limited to these Examples.

Example 1 Synthesis of bis (diethylene glycol monoethyl ether) ester of adipic acid
A 300 ml reactor equipped with a stirrer, a thermometer and a gas introduction tube was charged with 75 g (0.5 mol) of adipic acid and 206.3 g (1.5 mol) of diethylene glycol monoethyl ether, and 150 ° C. to 230 ° C. while blowing nitrogen. The mixture was heated to 0 ° C. and reacted for 27 hours while distilling off water. Subsequently, unreacted diethylene glycol monoethyl ether was distilled off under reduced pressure and steam deodorization was performed to obtain 185 g (yield 96%) of the target diester. The obtained ester was a colorless to pale yellow liquid having an acid value of 4.0 and a hue Gardner of 1 or less. The diester content was 99% from analysis by capillary gas chromatography (FID, area percentage).

Example 2 Synthesis of bis (triethylene glycol monoethyl ether) ester of adipic acid 47 g (0.32 mol) of adipic acid and 112 g of triethylene glycol monoethyl ether were added to a 300 mL reactor equipped with a stirrer, thermometer and gas introduction tube. (0.64 mol) was charged, heated to 150 ° C. to 250 ° C. while blowing nitrogen, reacted for 30 hours while distilling off water, steam deodorized, and the desired bis (triethylene glycol monoethyl ether) adipate ) 140 g of ester (yield 90%) was obtained. The ester thus obtained was a pale yellow liquid with an acid value of 8.5 and a hue Gardner 3. The diester content was 90% from analysis by capillary gas chromatography (FID, area percentage).

Example 3 Water-solubility Using the diester of the present invention obtained in Examples 1 and 2, and diethoxyethyl succinate, diethyl carbitol succinate, diethoxyethyl adipate, diethyl carbitol sebacate for comparison. The solubility in water was evaluated.
(Water solubility evaluation method)
Water was added to each diester so as to have the concentration shown in Table 1 and stirred, or the mixture was heated to 80 ° C. with stirring, then cooled to 25 ° C., and the solubility was visually evaluated.
(result)
The results are shown in Table 1. It has been found that the diester of the present invention has sufficient water solubility to be incorporated into a water-based cosmetic and a skin external preparation that does not use a surfactant.

Example 4 Oil-solubility Using the diester of the present invention obtained in Examples 1 and 2 and diethoxyethyl succinate, diethyl carbitol succinate, diethoxyethyl adipate, diethyl carbitol sebacate for comparison. The solubility in oil was evaluated.
(Oil solubility evaluation method)
To each diester, cetyl 2-ethylhexanoate was added to the concentration described in Table 1 and stirred, or once heated to 80 ° C. with stirring, then cooled to 25 ° C., and visually dissolved. evaluated.
(result)
The results are shown in Table 2. The diester of the present invention has high solubility in oil and is considered to have both hydrophilic and lipophilic functions.

Example 5 Evaluation of Feeling For the diester of the present invention, the feeling (moist feeling, non-stickiness, feeling of familiarity with skin) when applied to the skin was evaluated by 10 panelists. As a comparison object, diethoxyethyl succinate was used. The results are shown below. In the table, ◎ indicates that 8 or more out of 10 are good, ○ indicates that 6 to 7 out of 10 are good, △ indicates that 4 to 5 out of 10 are good, and × indicates 10 out of 10 It shows that 3 or less responded as good. From the results, the diester of the present invention was excellent in feeling such as moist feeling, no stickiness, and familiarity with the skin.

Compound name Moist feeling No stickiness Skin feel ------------------------------------- −
Diester of Example 1 ◎ ◎ ◎
Diester of Example 2 ◎ ○ ○
Diethoxyethyl succinate △ ◎ ×
-------------------------------------

Example 6 Evaluation of Aqueous Solution Stability The diester obtained in Example 1 of the present invention was evaluated for pH stability in a 1% aqueous solution. As comparison objects, diethoxyethyl succinate and diethyl carbitol succinate were used.
(Evaluation methods)
A 1% aqueous solution of each oil was prepared and stored in a thermostatic bath at 50 ° C. for 1 week, 2 weeks, 1 month, and changes in pH were evaluated. The results are shown in Table 3.
(result)
As shown in Table 3, the diester of the present invention had no problem in pH stability in an aqueous solution, and was excellent as an oil for cosmetics or a skin external preparation. On the other hand, diethoxyethyl succinate and diethyl carbitol succinate were inferior in pH stability in an aqueous solution.

（結果）
結果を表４に示した。なお、表中◎は１０名中８名以上が良好と回答、○は１０名中６〜７名が良好と回答、△は１０名中４〜５名が良好と回答、×は１０名中３名以下が良好と回答したことを示す。結果より、本発明品を配合した化粧水はコハク酸ジエトキシエチルを配合したものよりもしっとり感、肌へのなじみ感に優れていることがわかった。またグリセリンを配合したものよりもしっとり感があり、べたつきが無く、優れた感触であることがわかった。 Examples 7 and 8 Lotion Toner lotions having the composition shown in Table 4 were prepared using the diesters obtained in Examples 1 and 2 of the present invention, and diethoxyethyl succinate and glycerin as comparison targets, and applied to the skin. Ten panelists evaluated the feel (moist feeling, non-stickiness, and familiarity to the skin) when they were done.

(Preparation method)
No. 8-10 After uniformly mixing with a part of 14, add other ingredients while stirring to make uniform.

(result)
The results are shown in Table 4. In the table, ◎ indicates that 8 or more out of 10 are good, ○ indicates that 6 to 7 out of 10 are good, △ indicates that 4 to 5 out of 10 are good, and × indicates 10 out of 10 It shows that 3 or less responded as good. From the results, it was found that the skin lotion formulated with the product of the present invention was superior to those formulated with diethoxyethyl succinate with a moist feeling and familiarity with the skin. Moreover, it was found that it had a moist feeling, no stickiness, and an excellent feel as compared with the blended glycerin.

Example 9 Lotion Toner lotion having the following formulation was prepared. This skin lotion was not sticky, gave a moist feeling, and was excellent in familiarity with the skin.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 2 2.00
2 BG 1.00
3 Glycerin 2.00
4 Citric acid 0.01
5 Na citrate 0.10
6 Arginine 0.10
7 Glycyrrhizic acid 2K 0.05
8 Ethanol 7.00
9 Preservative appropriate amount
10 Fragrance
11 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1-6 are No. 11 and stirred and mixed uniformly (part A). Next, no. 9 to 10 are No. No. 8 after dissolution in No. 8 7 was added and dispersed (part B). A part was added to part B with stirring to make it uniform.

Example 10 Loosening Toner (Astringent Lotion)
An astringent lotion having the following formulation was prepared. This lotion was not sticky and gave a moist and smooth feeling.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 2.00
2 BG 2.00
3 Glycerin 0.04
4 Lactic acid 0.10
5 Lactic acid Na 0.05
6 Zinc phenol sulfonate 0.10
7 PEG-60 hydrogenated castor oil 0.50
8 Ethanol 15.00
9 Preservative appropriate amount
10 Fragrance
11 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1-7 are No. 11 and stirred and mixed uniformly (part A). Next, no. 9 to 10 are No. 8 (part B). A part was added to part B with stirring to make it uniform.

Example 11 Cosmetic liquid A cosmetic liquid having the following formulation was prepared. This essence had a smooth feel while softening the skin and keeping the skin fresh and smooth.

Component Blending amount (% by weight)
----------------------------------
Part A Diester of Example 1 2.00
Preservative appropriate amount PEG-40 hydrogenated castor oil 0.20
Purified water 5.00
Part B xanthan gum 0.40
Carbomer 0.10
BG
10.00
White jellyfish polysaccharide (Nippon Seika) 0.10
Purified water Amount to be 100 in total C part hydroxylated K (1% aqueous solution)
Purified water 10.00
Part D glycyrrhizic acid 2K 0.20
Purified water 5.00
----------------------------------
(Production method)
Part A was dissolved at room temperature. C. Part C was gradually added to part B while stirring to obtain a viscous liquid, and then parts A and D were added and stirred to make uniform.

Example 12 Shampoo A shampoo having the following formulation was prepared. This shampoo was able to give moist and smooth fingering to the hair.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 2 2.00
2 Cocamidopropyl betaine (40%) 40.00
3 Cocoa glutamate TEA (27%) 10.00
4 Tetradecenesulfonic acid Na (36%) 2.00
5 PEG120-Methylglucose dioleate 3.00
6 Triethanolamine 0.20
7 Methylisothiazolinone 0.01
8 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1 to 5 were heated to about 80 ° C. and dissolved uniformly (part A). Next, no. 6-8 were heated to about 80 ° C. and dissolved uniformly (part B). Part B was added to part A and mixed with stirring at about 80 ° C. until uniform, and then cooled.

Example 13 Shampoo A shampoo having the following formulation was prepared. This shampoo was able to give moist and smooth fingering to the hair.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 1.00
2 Cocamidopropyl betaine (30%) 30.00
3 Laureth sulfate Na (25%) 14.00
4 Lauryl sulfate Na 1.00
5 Cocamide DEA 1.00
6 Methylparaben 0.20
7 Phenoxyethanol 0.80
8 Polyquaternium-10 0.60
9 Citric acid 0.05
10 Water Total amount of 100 --------------------------------
(Preparation method)
No. 1 to 7 were heated to about 70 ° C. and dissolved uniformly (part A). Next, no. 8, no. 10 was heated to about 70 ° C. and dissolved uniformly (part B). Part B was added to part A and mixed uniformly, and then cooled. Furthermore, no. 9 was added and mixed uniformly.

Example 14 Shampoo A shampoo having the following formulation was prepared. This shampoo was able to give moist and smooth fingering to the hair.

Component Blending amount (% by weight)
--------------------------------
1 Diester obtained in Example 1 3.00
2 Cocoa glutamate TEA (27%) 20.00
3 Tetradecenesulfonic acid Na (36%) 1.50
4 PEG120-methyl glucose dioleate 1.50
5 Polyquaternium-10 0.20
6 Methylisothiazolinone 0.01
7 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1-4 were heated to about 80 ° C. and dissolved uniformly (part A). Next, no. 5 to 7 were heated to about 80 ° C. and dissolved uniformly (part B). Part B was added to part A and mixed with stirring at about 80 ° C. until uniform, and then cooled.

Example 15 Treatment A treatment having the following formulation was prepared. This treatment was able to give the hair a moist feeling and smooth fingering.

Component Blending amount (% by weight)
--------------------------------
1 Cetanol 8.00
2 Oleyl alcohol 1.00
3 Dimethicone (100cs) 1.00
4 Glyceryl stearate 1.00
5 Plandool-H (Nippon Seika) 1.00
6 Methylparaben 0.20
7 Diester of Example 1 1.00
8 Behentrimonium chloride 2.40
9 Hydroxyethyl cellulose 0.40
10 Water Total amount of 100 --------------------------------
(Preparation method)
No. 1 to 8 were heated to about 70 ° C. and dissolved uniformly (part A). Next, no. 9 to 10 were heated to about 70 ° C. and dissolved uniformly (part B). Part B was added to part A and stirred and mixed uniformly, and then cooled to room temperature.

Example 16 Treatment A treatment having the following formulation was prepared. This treatment was able to give the hair a moist feeling and smooth fingering.

Component Blending amount (% by weight)
--------------------------------
1 Cetanol 5.00
2 Oleyl alcohol 1.00
3 Olive oil 2.00
4 Glyceryl stearate 1.00
5 Dicocodimonium chloride 0.80
6 Behentrimonium chloride (80%) 2.40
7 Diester of Example 2 2.00
8 Tocopherol 0.05
9 Propylparaben 0.10
10 Methylparaben 0.10
11 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1 to 10 were heated to about 70 ° C. and dissolved uniformly (part A). No. in part A 11 was added and stirred and mixed uniformly, and then cooled to room temperature.

Example 17 Styling Gel A styling gel having the following formulation was prepared. When applied to hair, this styling gel was not sticky, did not move even when it was applied, and had high hair adhesion due to its high adhesion, and had excellent hairstyle durability.

Component Blending amount (% by weight)
--------------------------------
1 STRUCTURE 2001 (made by NSC Japan) 5.00
2 TEA (50%) 3.50
3 AMPHOMER SH30 (made by NSC Japan) 3.00
4 Ethanol (95%) 3.00
5 Methylisothiazolinone 0.01
6 Diester of Example 1 2.00
7 Glycolic acid
8 TEA appropriate amount
9 Water Amount that totals 100 --------------------------------
(Preparation method)
No. No. 9 no. 6 was dissolved by heating. 2, no. 5 is dissolved (part A). No. in part A 1 is gradually added and mixed uniformly (part B). No. No. 3 4 and dissolved in part B cooled to 40 ° C. while mixing and dissolved uniformly. No. 7 or No. 8 adjust the pH to 7.0-7.5.

Example 18 Emollient Cream An emollient cream having the following formulation was prepared. This emollient cream was a cream excellent in the effect of imparting a moist feeling.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 2.00
2 Hydrogenated palm oil 2.50
3 Behenyl alcohol 2.00
4 Dimethicone (10cs) 1.50
5 Glyceryl stearate 1.50
6 Stearyl alcohol 1.20
7 Stearic acid PG (SE) 1.00
8 PEG-60 glyceryl isostearate 1.00
9 Octyl methoxycinnamate 0.20
10 Ethylparaben 0.10
11 1,3-butylene glycol 6.00
12 Glycerin 1.00
13 Phenoxyethanol 0.20
14 Methylparaben 0.15
15 Purified water 79.65
--------------------------------
(Preparation method)
No. 1-10 were added, and it heated and melt | dissolved at about 80 degreeC (A part). No. in a separate container. 11 to 15 were taken, heated to about 80 ° C., and dissolved uniformly (part B). Part B was added to part A, emulsified with a homomixer, and then cooled to 40 ° C.

Example 19 Sunscreen Agent A sunscreen agent having the following formulation was prepared. This sunscreen agent was a cream that suppressed breakage due to sweat and had a moist feeling.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 11.70
2 Squalane 22.50
3 LUSPLAN PI-DA (Nippon Seika) 2.70
4 Microcrystalline wax 2.70
5 Distearate Al 1.60
6 Mg stearate 1.60
7 1,3-butylene glycol 5.00
8 Behenyl alcohol 4.80
9 Composite-PC (Nippon Seika) 1.00
10 Cholesterol 0.80
11 Propylparaben 0.20
12 Methylparaben 0.20
13 Titanium oxide 9.00
14 Mg sulfate 0.50
15 Purified water 35.70
--------------------------------
(Preparation method)
No. No. 13 Nos. 1 and 2 3 was added and kneaded with a mill (part A). No. in a separate container. No. 2 4-6 were added and it heated and dissolved at about 150 degreeC (part B). No. in a separate container. No. 1 No. 7-12 were added, and it heated and dissolved at about 80 degreeC (part C). No. in a separate container. 14, 15 was added, and the mixture was heated to about 80 ° C. and dissolved (part D). Part C was added to part B, mixed, and then added to part A and mixed uniformly. Subsequently, D part was added, it stirred, and it cooled to 40 degreeC after emulsification.

Example 20 Base Cream A base cream having the following formulation was prepared. This base cream was a base cream that had a good elongation, had a foundation, had a good feel, and was able to impart a light touch.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 2 5.00
2 Cyclomethicone 15.00
3 Trimethylsiloxysilicate 3.00
4 Glyceryl stearate (SE) 2.00
5 PG stearate (SE) 2.00
6 Macadamia nut fatty acid phytosteryl 2.00
7 Stearic acid 0.50
8 Palmitic acid 0.50
9 Octyl methoxycinnamate 0.50
10 Tocopherol 0.20
11 1,3-butylene glycol 10.00
12 Mica 8.00
13 Talc 7.00
14 Phenoxyethanol 0.80
15 Titanate (Li / Cobalt) 0.20
16 Xanthan gum (10%) 2.00
17 Cellulose gum (10%) 2.00
18 Purified water 39.30
--------------------------------
(Preparation method)
No. 16 and 17 are No. It was dissolved in 18 to give a viscous liquid (2%) (part A). No. in a separate container. 1-10 was added, and it heated and dissolved at about 80 degreeC (B part). No. in a separate container. 11-15, no. The remainder of 18 was added and heated to about 80 ° C. and dissolved (part C). After adding part C to part B and emulsifying, part A was added and mixed uniformly. It cooled to 40 degreeC after stirring.

Example 21 Foundation A foundation having the following formulation was prepared. This foundation had excellent color development and a moist feel.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 6.00
2 Cyclomethicone 3.50
3 Dimethicone (5cs) 2.00
4 Trimethylsiloxysilicic acid 1.50
5 Octyl methoxycinnamate 1.00
6 Phenoxyethanol 0.40
7 Tocopherol 0.10
8 Mica 39.60
9 Talc 24.00
10 Titanium oxide 20.00
11 Iron oxide 1.90
--------------------------------
(Preparation method)
Each component was stirred at high speed and mixed uniformly.

Example 22 Lipstick A lipstick having the following formulation was prepared. This lipstick was fresh and highly adhesive.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 1.00
2 Cetyl octoate 22.50
3 Trioctanoin 28.50
4 Cyclomethicone 16.00
5 Ceresin 9.00
6 Candelilla wax 5.00
7 LUSPLAN PI-DA (Nippon Seika) 5.00
8 Sorbitan sesquiisostearate 4.00
9 Macadamia nut oil 1.00
10 Tocopherol 0.50
11 Iron oxide 2.25
12 Titanium oxide 2.25
13 Mica 1.50
14 Red 202 1.50
--------------------------------
(Preparation method)
No. Nos. 11-14 are No. 1 and 2 were kneaded (part A). No. in a separate container. 3 to 10 were added, and the mixture was heated to about 80 ° C. and dissolved (Part B). At about 80 ° C., part A was added to part B, dissolved, and then rapidly cooled.

Example 23 Lip Gloss A lip gloss having the following formulation was prepared. The lip gloss was fresh and had high adhesion.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 2.00
2 Dextrin palmitate 10.00
3 Macadamia nut oil fatty acid phytosteryl 43.00
4 Methylphenylpolysiloxane 30.00
5 Trioctanoin 10.00
6 Liquid paraffin 5.00
--------------------------------
(Preparation method)
No. 1 and 2 were heated to 100-110 degreeC, and were dissolved uniformly. Next, no. 3-6 were added and it was made to melt | dissolve uniformly at about 80 degreeC.

Example 24 Cleansing oil A cleansing oil having the following formulation was prepared. This cleansing oil had a refreshing feel and was well-familiar with foundations, makeup, etc., and could be quickly removed.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 1.00
2 Laureth-4 7.00
3 Tocopherol appropriate amount
4 Propylparaben appropriate amount
5 Cetyl octoate Total amount of 100
6 Mineral oil 10.00
--------------------------------
(Preparation method)
All ingredients were heated and dissolved and mixed.

Example 25 Mascara A mascara having the following formulation was produced. This mascara had good adhesion, good usability, and good stability.

Component Blending amount (% by weight)
---------------------------------
1 Iron oxide (black) 10.00
2 Light isoparaffin 30.00
3 Polyacrylate emulsion 30.00
4 Solid paraffin 8.00
5 Diester of Example 2. 1.20
6 Sorbitan sesquioleate 4.00
7 Preservative appropriate amount
8 Perfume appropriate amount
9 Purified water Total amount of 100 ---------------------------------
(Preparation method)
No. No. 9 no. No. 1 was added and dispersed with a homomixer. 3 was added and heated to 70 ° C (aqueous phase). The other ingredients were mixed and heated to 70 ° C. (oil phase). The aqueous phase was added to the oil phase, and the mixture was uniformly emulsified and dispersed with a homomixer to obtain the desired mascara.

Example 26 Eyeshadow An eye shadow having the following formulation was produced. This eye shadow had good adhesion, good usability, and good emulsification stability.

Component Blending amount (% by weight)
------------------------------
1 Talc 10.00
2 Kaolin 2.00
3 facial 5.00
4 Diester of Example 1 3.00
5 Stearic acid 3.00
6 Isopropyl myristate 5.00
7 Liquid paraffin 5.00
8 Propylene glycol monolaurate 3.00
9 Antioxidant appropriate amount
10 Incense amount
11 1,3-butylene glycol 5.00
12 Glycerin 1.00
13 Preservative appropriate amount
14 Triethanolamine 1.20
15 Suitable amount of sequestering agent
16 Purified water Total amount of 100 ---------------------------------
(Preparation method)
No. 1-3 were mixed with a blender and then processed with a pulverizer (powder part). No. 11 to 16 were heated and dissolved at 70 to 75 ° C. (aqueous phase part). No. 4 to 10 were dissolved by heating at 70 to 80 ° C. (oil phase part). The powder part was added to the aqueous phase part and mixed with stirring. The oil phase was added to this while stirring, dispersed with a homomixer, and stirred and cooled to room temperature to obtain the desired eye shadow.

Example 27 Mild Shampoo A mild shampoo having the following formulation was prepared. This mild shampoo was a shampoo capable of imparting a moist feeling to the hair and providing smooth fingering.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 0.50
2 Cocoyl methyl methyl taurine Na (30%) 30.00
3 Cocamidopropyl betaine (30%) 20.00
4 Laureth-12 Na acetate (30%) 5.00
5 1,3-Butylene glycol 1.00
6 Cocamide MEA 2.00
7 Glycol distearate 1.50
8 Polyquaternium-10 0.50
9 Polyquaternium-7 0.30
10 Cationic NH (Nippon Seika) 0.50
11 Sodium benzoate 0.40
12 Phenoxyethanol 0.20
13 Methylparaben 0.20
14 Purified water 37.90
--------------------------------
(Preparation method)
No. 1 to 7 were heated to about 80 ° C. and dissolved (part A). No. in a separate container. 8 to 14 were heated to about 80 ° C. and dissolved (Part B). While stirring Part B into Part A, they were gradually added and mixed uniformly, and then rapidly cooled.

Example 28 Moisture The following formula was prepared. This moisturizing was a non-sticky rinse that gave the hair a moist feeling and a smooth fingering.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 0.10
2 Plandool-H (Nippon Seika) 0.50
3 Cetrimonium chloride (30%) 5.20
4 Octild decanol 4.70
5 Cetanol 2.80
6 Steartrimonium chloride (63%) 0.60
7 Cetyl octanoate 0.30
8 Squalane 0.30
9 Myristyl sulfate Na 0.20
10 Seths-40 0.10
11 Ores-5 0.10
12 Cetyl sulfate Na 0.10
13 Citric acid 0.10
14 Methylparaben 0.10
15 Purified water 84.80
--------------------------------
(Preparation method)
No. 1 to 12 were heated to about 80 ° C. and dissolved (part A). No. in a separate container. 14 to 15 were heated to about 80 ° C. and dissolved (part B). While stirring Part B into Part A, gradually add and mix uniformly. After 13 was added and stirred, it was quenched.

Example 29 Treatment A treatment having the following formulation was prepared. This treatment was a treatment that kept the moisture of the hair and was able to give a supple, moist and smooth feel.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 2 2.00
2 Glyceryl stearate (SE) 4.50
3 Steerless-10 4.00
4 Cetanol 4.00
5 Steartrimonium chloride (63%) 1.80
6 LUSPLAN DD-IS (Nippon Seika) 1.50
7 Behentrimonium chloride (80%) 1.00
8 Methylparaben 0.20
9 Purified water 81.00
--------------------------------
(Preparation method)
No. No. 9 was heated to about 80 ° C. 8 was added and dissolved (part A). No. in a separate container. 1-7 were added, and it heated and dissolved (part B). Part A was gradually added to part B and mixed uniformly.

Example 30 Straight Perm Agent (Cation Type)
One part and two parts of a straight perm agent (cation type) having the following formulation were prepared. This straight perm solution is a straight perm solution that can be applied firmly to the straight perm because of its high adhesiveness to the hair and setting power.

(1 liquid)
Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 0.50
2 Cetanol 5.00
3 Steartrimonium chloride (63%) 2.40
4 Seths-20 2.40
5 TRIBEHENIN PEG-20 ESTERS 2.00
6 Seths-6 0.80
7 Lauramide MIPA 0.80
8 PEG-60 hydrogenated castor oil 0.40
9 Ammonium thioglycolate solution (50%) 13.50
10 Monoethanolamine 1.70
11 Polyquaternium-6 1.30
12 Hydrolyzed soy protein 1.00
13 EDTA-4Na 0.10
14 Ammonia water (28%) 1.10
15 Purified water 67.00
--------------------------------
(Preparation method)
No. Most of 15 were heated to about 80 ° C. (Part A). No. in a separate container. 1-8 were added and it heated and dissolved (part B). No. in a separate container. No.15, no. 9 to 13 were added and dissolved uniformly (part C). Part B was added to part A, mixed and stirred, and part C was added at about 45 ° C. and mixed uniformly. After cooling to room temperature, no. 14 was added.

(2 liquids)
Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 2.00
2 Cetanol 5.00
3 Emmacol VT-20 (Sanei Chemical) 5.00
4 Dimethicone (200cs) 2.00
5 Trioctanoin 2.00
6 Octyldodecanol 0.60
7 Seths-20 0.50
8 Diammonium phosphate 0.20
9 Sodium benzoate 0.15
10 Na bromate 8.00
11 Purified water 74.55
--------------------------------
(Preparation method)
No. 1-7 were added, it heated at about 70 degreeC, and it was made to melt | dissolve (A part). No. in a separate container. No. 11 was taken and heated to about 70 ° C. 8 and 9 were added and dissolved (part B). No. in a separate container. No. 11 was taken and heated to about 60 ° C. 10 was added and dissolved (part C). At about 70 ° C., part B was added to part A and stirred until the viscosity increased. The mixture was cooled to 60 ° C., and part C was added with stirring and mixed uniformly. After the temperature dropped to about 50 ° C., it was rapidly cooled.

Example 31 Hair depigmenting agent (2 agent type)
Using the compound D obtained in Example 4, a hair bleaching agent (two-agent formula) having the following formulation was prepared. This depigmenting agent (two-component type) is a depigmenting agent that reduces the feeling of hair damage after depigmentation and gives the hair a good feel such as softness, moistness, and slipping. there were.

(1 agent)
Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 2 0.50
2 Polyoxyethylene oleyl ether 52.00
3 Ammonia water (25%) 25.50
4 Cetrimonium chloride (30%) 10.00
5 Ethanol 10.00
6 Purified water 4.50
--------------------------------
(Preparation method)
Each component was stirred and mixed uniformly.

(2 agents)
Component Blending amount (% by weight)
--------------------------------
1 Hydrogen peroxide solution
17.00
2 Cetrimonium chloride (30%)
10.00
3 Cetanol 3.00
4 Seths-2 1.00
5 Seths-20 1.00
6 Na pyrophosphate 0.10
7 Diethylenetriaminepentaacetic acid 0.10
8 Citric acid (50%) appropriate amount
9 Purified water Total amount of 100 --------------------------------
(Preparation method)
Each component was mixed uniformly, and the pH was adjusted to 3.5 to 4.0 with citric acid.
(Mixing ratio)
1 agent: 2 agents = 1: 7

Example 32 Oxidative hair dye An oxidative hair dye having the following formulation was prepared. This oxidative hair dye is an oxidative hair dye that reduces the feeling of hair damage after hair dyeing and gives the hair a good feel such as flexibility, moist feeling, and slipperiness. It was.

(1 agent)
Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 0.50
2 Cetrinium chloride (25%) 24.00
3 Cetanol 9.00
4 Octild decanol 9.00
5 Monoethanolamine 3.80
6 Ammonia water 2.00
7 Myristyl sulfate Na 1.50
8 Ores-20 1.40
9 Toluene-2,5-diamine hydrochloride 1.00
10 Resorcin 1.00
11 Metaaminophenol 0.50
12 Paraaminophenol 0.20
13 Orthoaminophenol 0.10
14 Ascorbic acid 0.20
15 Fragrance 0.10
16 Purified water 45.70
--------------------------------
(Preparation method)
Each component was mixed uniformly.

(2 agents)
Component Blending amount (% by weight)
--------------------------------
1 Hydrogen peroxide solution
17.00
2 Cetrinium chloride (30%)
10.00
3 Cetanol 3.00
4 Seths-2 1.00
5 Seths-20 1.00
6 Na pyrophosphate 0.10
7 Diethylenetriaminepentaacetic acid 0.10
8 Citric acid (50%) appropriate amount
9 Purified water Total amount of 100 --------------------------------
(Preparation method)
Each component was mixed uniformly, and the pH was adjusted to 3.5 to 4.0 with citric acid.
(Mixing ratio)
1 agent: 2 agents = 1: 1

Example 33 Curling Agent A curling agent having the following formulation was produced. By using the curl agent 1 and 2 produced in this way for the hair, it was possible to curl with good flexibility, slipperiness, moist texture, and good finish.

(1 liquid)
Component Blending amount (% by weight)
------------------------------
1 Cysteamine hydrochloride 2.00
2 DL cysteine 0.40
3 Monoethanolamine 0.90
4 Ammonia water (28%) 0.50
5 POE20 palm oil fatty acid sorbitan 0.50
6 Fragrance 0.10
7 Diallylammonium chloride / acrylic acid copolymer 1.00
8 Emmacol VT-20 (Sanei Chemical) 3.00
9 Ores-20 0.50
10 Ores-50 0.20
11 Diester of Example 1 0.50
12 Lanolin fatty acid octyldodecyl (Nippon Seika) 0.30
13 Sorbitan monostearate 0.20
14 tetrasodium edetate tetrahydrate 0.10
15 Ammonium phosphate 0.50
16 Purified water Total amount of 100 ---------------------------------
(Preparation method)
No. No. 16 in part (20%) 1 to 3 was added and dissolved, and No. 1 was previously stored in a separate container. No. 16 in part (10%) What was melt | dissolved by adding 14 and 15 was added at about 40 degreeC, and it was made to melt | dissolve uniformly (part A). In another container, no. The remainder of 16 was warmed to about 75 ° C. (Part B). In another container 8-13 were taken and heated to about 75 ° C. to dissolve (Part C). After adding part B to part C and emulsifying and stirring and mixing well, it was cooled to 40 ° C. and part A was added and stirred uniformly. Next, no. No. 7 was added and stirred. Nos. 5 and 6 were added. 4 was added, and the mixture was stirred and mixed uniformly to adjust the pH to 9.0 to 9.5, thereby obtaining the target curling agent 1 solution.

(2 liquids)
Component Blending amount (% by weight)
----------------------------------
1 EDTA-2Na 0.10
2 Na bromate 4.00
3 Ammonium phosphate 0.50
4 Cationic NH (Nippon Seika) 2.00
5 Cetrinium chloride (30%) 1.00
6 Ores-50 0.20
7 Dimethicone copolyol 0.50
8 Sodium benzoate 0.15
9 Purified water Total amount of 100 -----------------------------------
(Preparation method)
No. 4-7 were heated to about 80 ° C. and dissolved (part A). In another container 9 (70%) and No. 9 1 and 8 were added and heated to about 80 ° C. to dissolve (Part B). In another container, no. No. 9 and No. 9 A few were added and heated to about 50 ° C. to dissolve (Part C). Add part B to part A and mix and stir uniformly to emulsify, then add part C when the temperature reaches 40 ° C., mix well, and adjust the pH to 6.5 to 6.8 at room temperature. Curl agent 2 liquid was obtained.

Example 34 Pasty lipstick A pasty lipstick having the following formulation was prepared. This lipstick was excellent in terms of gloss and odor, and had a smooth and sticky feeling when applied.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 2.00
2 12-Hydroxystearic acid 8.00
3 Liquid paraffin Amount that totals 100
4 Trioctanoin 30.00
5 Silicic anhydride 0.30
(Aerosil R974 manufactured by Nippon Aerosil Co., Ltd.)
6 Red 202 No.
7 Yellow No. 4 Suitable amount ----------------------------
(Preparation method)
No. 1-7 are heated and mixed uniformly.

Example 35 Solid powder foundation A solid powder foundation having the following formulation was prepared. This solid powder foundation was excellent in feeling of use, adhesion to the skin, persistence of makeup, smell and the like.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 10.00
2 Perfluoropolyether 5.00
3 Silicone-treated sericite 60.00
4 Titanium oxide 10.00
5 Powdered synthetic hydrocarbon wax 1.00
6 Yellow iron oxide 1.00
7 Bengala 0.50
8 Methylparaben 0.50
9 Black iron oxide 0.05
10 Talc Total amount of 100 --------------------------------
(Preparation method)
No. Add 1-2, warm to about 70 ° C. and mix (Part A). No. in a separate container. 3 to 10 are mixed and dispersed (part B). Add part A to part B and mix evenly.

Example 36 Hair Cream A hair cream having the following formulation was prepared. This hair cream was glossy, non-sticky, kept the moisture of the hair, and was able to give a smooth feel.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 2 2.00
2 Cetanol 4.00
3 Dimethicone (500cs) 13.00
4 Glyceryl stearate 2.80
5 Ores-10 phosphate 0.80
6 Glyceryl stearate (SE) 1.60
7 Phenoxyethanol 0.40
8 Methylparaben 0.20
9 10% NaOH 0.60
10 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1 to 6 were heated to about 80 ° C. and dissolved (part A). No. in a separate container. 7-10 were added, and it heated and melt | dissolved at about 80 degreeC (B part). Part B was added to part A and mixed with stirring.

Example 37 Hair Cream A hair cream having the following formulation was prepared. This hair cream was glossy, non-sticky, kept the moisture of the hair, and was able to give a smooth feel.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 1.00
2 Cetanol 4.00
3 Isodecyl neopentanoate 15.00
4 Stearic acid PG (SE) 1.70
5 Glyceryl stearate 2.70
6 Ores-8 phosphate 0.70
7 Phenoxyethanol 0.40
8 Methylparaben 0.20
9 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1 to 6 were heated to about 80 ° C. and dissolved (part A). No. in a separate container. 7-9 was added, and it heated and dissolved at about 80 degreeC (part B). Part B was added to part A and mixed with stirring.

Example 38 Rinse-in shampoo A rinse-in shampoo having the following formulation was prepared. This rinse-in shampoo imparts a moist feeling to the hair and can provide smooth fingering.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 1.00
2 Cocamidopropyl betaine (30%) 20.00
3 Lauryl sulfate TEA (40%) 15.00
4 Cocamide DEA 2.00
5 Cocoa glutamate TEA (30%) 30.00
6 Ethylene glycol distearate 1.20
7 Polyquaternium-10 1.60
8 Stearyl trimonium bromide (70%) 0.60
9 Phenoxyethanol 0.20
10 Methylparaben 0.20
11 Sodium benzoate 0.40
12 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 7, 8 and 12 were heated to about 80 ° C. and mixed with stirring. Next, no. 3 is added and mixed. Add 1, 2, 4 to 6 and stir until uniform. 9-11 were added and dissolved.

Example 39 Shampoo A shampoo having the following formulation was prepared. This shampoo was able to give a moist feeling to the hair and give smooth fingering.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 2 0.80
2 Sodium lauryl sulfate (25%) 45.00
3 Olefin (C14-16) sulfonic acid Na (37%) 4.00
4 Cocamidopropyl betaine (30%) 6.00
5 Cocamide DEA 3.40
6 Ethylene glycol distearate 1.80
7 Phenoxyethanol 0.20
8 Methylparaben 0.20
9 Sodium benzoate 0.40
10 Glycerin 2.40
11 10% citric acid appropriate amount
12 Polyquaternium-10 0.80
13 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 12-13 were heated to about 80 ° C. and dissolved uniformly. Next, no. Add 2-6 and stir and mix at about 80 ° C. until uniform, then No. 2 1 was added and dissolved uniformly. Furthermore, no. 7-10 are added and dissolved. 11 to pH 6-7.

Example 40 Treatment A treatment having the following formulation was prepared. This treatment was a treatment capable of keeping the moisture of the hair and imparting a moist and smooth feel to the hair.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 2 0.80
2 Cetanol 6.00
3 Trioctanoin 1.60
4 Cetyl octanoate 1.60
5 Stearyl trimonium bromide (70%) 0.60
6 Dimethylaminopropylamide stearate 1.00
7 10% citric acid 2.00
8 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1 to 6 were heated to about 80 ° C. and dissolved uniformly. Next, No. 2 was heated to about 80 ° C. No. 8 was added and mixed uniformly. 7 was dissolved.

Example 41 Treatment A treatment having the following formulation was prepared. This treatment was a treatment capable of keeping the moisture of the hair and imparting a moist and smooth feel to the hair.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 1.00
2 Cetanol 6.00
3 Squalane 2.00
4 Trioctanoin 2.00
5 Dimethylaminopropylamide stearate 2.00
6 Cocoamphoacetate Na (30%) 1.60
7 Phenoxyethanol 0.40
8 Lactic acid 0.80
9 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1 to 6 were heated to about 80 ° C. and dissolved uniformly (part A). Next, no. 7-9 were added and it was made to melt | dissolve uniformly (B part). Part B was added to part A and dissolved uniformly.

Example 42 Emollient Cream An emollient cream having the following formulation was prepared. This emollient cream was a cream excellent in the effect of imparting a moist feeling.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1. 1.20
2 Cetyl octanoate 6.60
3 Hydrogenated palm oil 4.20
4 Glyceryl stearate (SE) 2.20
5 PEG-60 glyceryl isostearate 1.90
6 Stearic acid PG (SE) 0.60
7 Stearyl alcohol 0.60
8 Dimethicone (10cs) 1.80
9 Ethylparaben 0.10
10 1,3-butylene glycol 3.00
11 Glycerin 1.00
12 Phenoxyethanol 0.20
13 Methylparaben 0.15
14 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1 to 9 were heated to about 70 ° C. and dissolved uniformly (part A). Next, no. 10-14 were heated to about 70 ° C. and dissolved uniformly (part B). To Part A, Part B was added with stirring and emulsified, and then cooled.

Example 43 Emollient Cream An emollient cream having the following formulation was prepared. This emollient cream was a cream excellent in the effect of imparting a moist feeling.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 2 1.00
2 Cetyl octanoate 5.00
3 PEG-60 glyceryl isostearate 1.50
4 Hydrogenated palm oil 14.00
5 Ethylparaben 0.20
6 Stearyl alcohol 3.50
7 Glyceryl stearate (SE) 1.00
8 Steerless-6 1.50
9 PEG-8 distearate 1.00
10 Cetanol 3.00
11 Cetyl palmitate 2.00
12 Isocetyl myristate 5.00
13 Cetyl dimethicone copolyol 0.50
14 Tocopherol 0.20
15 Dimethicone (10cs) 1.00
16 Glycerin 4.00
17 Methylparaben 0.20
18 1,3-butylene glycol 6.00
19 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1 to 15 were heated to about 70 ° C. and dissolved uniformly (part A). Next, no. 16 to 19 were heated to about 70 ° C. and dissolved uniformly (part B). To Part A, Part B was added with stirring and emulsified, and then cooled.

Example 44 Massage Cream A massage cream having the following formulation was prepared. This massage cream was a cream having a high massage effect and excellent moisturizing effect.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 4.00
2 Macadamia nut fatty acid phytosteryl 8.00
3 Glyceryl stearate (SE) 2.00
4 Polysorbate 60 1.80
5 Sorbitan stearate 1.00
6 Polyglyceryl stearate-10 0.50
7 Cholesterol 0.20
8 Dimethicone (10cs) 1.00
9 Myristyl alcohol 1.00
10 Stearic acid 1.00
11 Stearyl alcohol 0.50
12 Behenyl alcohol 0.50
13 Hydrogenated palm oil 9.00
14 Tocopherol 0.10
15 Isostearyl palmitate 2.00
16 Cetyl octanoate 15.00
17 Ethylparaben 0.20
18 Phenoxyethanol 0.20
19 Methylparaben 0.10
20 1,3-butylene glycol 10.00
21 Glycerin 3.00
22 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1 to 17 were heated to about 70 ° C. and dissolved uniformly (part A). Next, no. 18-22 was heated to about 70 ° C. and dissolved uniformly (part B). To Part A, Part B was added with stirring and emulsified, and then cooled.

Example 45 Emulsion An emulsion having the following formulation was prepared. This emulsion was excellent in the effect of imparting a moist feeling.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1. 2.50
2 Sorbitan stearate 0.50
3 PEG-10 stearate 0.50
4 Polysorbate 60 0.50
5 Cetyl octanoate 3.70
6 Cetanol 1.20
7 Dimethicone (10cs) 1.00
8 Ethylparaben 0.10
9 1,3-butylene glycol 3.00
10 (Eicosandioic acid / Tetradecanedioic acid) Polyglyceryl-10 Esters 1.00
11 Glycerin 1.00
12 Phenoxyethanol 0.20
13 Methylparaben 0.15
14 Citric acid 0.01
15 Na citrate 0.09
16 Xanthan gum 0.10
17 Carbomer 0.15
18 Hydroxide K 0.06
19 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 16 is a part of No.16. In addition to 19, the mixture was stirred to obtain a viscous liquid (Part A). No. 17 in some No. No. 19 and stirring, No. 19 18 was added to obtain a viscous liquid (Part B). Next, no. 1 to 8 were heated to about 70 ° C. and dissolved (part C). No. 9-15, the remaining No. 19 was heated to about 70 ° C. and dissolved (part D). Part D was added to part C with stirring and emulsified, then cooled to about 50 ° C., part A and part B were added and stirred until uniform.

Example 46 Lip Gloss A lip gloss having the following formulation was prepared. This lip gloss was glossy, fresh and had high adhesion.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 7.70
2 LUSPLAN DD-DA7 (Nippon Seika) 17.00
3 Cetyl octanoate 33.00
4 Dextrin palmitate 7.00
5 Mica 9.00
6 Sulfuric acid Ba 25.00
7 Red 104 (1) 0.50
8 Yellow 203 0.80
--------------------------------
(Preparation method)
No. No. 4 In addition to a part of 3, it was heated to about 100-110 ° C. and dissolved uniformly (part A). Next, no. 1, 2 and the remaining No. 3, no. 5-8 were added and it mixed by the roll mill (B part). Part A and part B were added, heated to about 60 ° C., stirred and mixed uniformly, then filled into a mold and rapidly cooled.

Example 47 Foundation A foundation having the following formulation was prepared. This foundation had excellent color development and a moist feel.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 2 6.00
2 Mica 39.50
3 Talc 24.00
4 Titanium oxide 20.00
5 Iron oxide 1.90
6 Cyclomethicone 3.50
7 Trimethylsiloxysilicic acid 1.50
8 Octyl methoxycinnamate 1.00
9 Dimethicone (10cs) 2.00
10 Tocopherol 0.20
11 Phenoxyethanol 0.40
--------------------------------
(Preparation method)
No. 1 to 11 were mixed uniformly.

Example 48 Liquid Foundation A liquid foundation having the following formulation was prepared. This liquid foundation was excellent in usability and adhesion to the skin.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 5.00
2 Glyceryl stearate (SE) 1.00
3 Stearic acid PG (SE) 1.00
4 Cetyl octanoate 6.00
5 Tocopherol 0.10
6 Propylparaben 0.10
7 Titanium oxide / iron oxide mixture 18.00
(Toyo Pigment Co., Ltd. FDP-W-007)
8 Mica 7.00
9 Trimethylsiloxysilicate 3.00
10 Cyclomethicone 7.00
11 Phenylmethicone 5.00
12 Cellulose gum 0.10
13 Xanthan gum 0.20
14 1,3-butylene glycol 5.00
15 Methylparaben 0.20
16 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 12 is a part of No. 12. 16 and stirred to give a viscous liquid (Part A). No. 13 for some No. 13 16 and stirred to give a viscous liquid (Part B). Next, no. 1 to 6 and 9 to 11 were added, and the mixture was heated to about 70 ° C. and dissolved (part C). No. 7, 8, 14, 15 and the remaining No. 16 was heated to about 70 ° C. and dissolved (part D). Part D was added to part C with stirring and emulsified, then cooled to about 50 ° C., part A and part B were added and stirred until uniform.

Example 49 Treatment A treatment having the following formulation was prepared. This treatment was a treatment capable of keeping the moisture of the hair and giving the hair a gloss, moist feeling, and a smooth feel.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 2 2.00
2 Cetanol 5.00
3 Olive oil 2.00
4 Behentrimonium chloride (80%) 2.40
5 Distearyldimonium chloride (75%) 0.80
6 Glyceryl stearate 1.00
7 Methylparaben 0.10
8 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1 to 6 were heated to about 80 ° C. and dissolved uniformly (part A). In another container 7 to 8 were taken, heated to about 80 ° C., and uniformly dissolved (part B). B part was gradually added to part A and mixed uniformly.

Example 50 Treatment A treatment having the following formulation was prepared. This treatment was a treatment capable of keeping the moisture of the hair and giving the hair a gloss, moist feeling, and a smooth feel.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 1.00
2 Cetanol 5.00
3 Oleyl alcohol 1.00
4 Behentrimonium chloride (80%) 2.40
5 Distearyldimonium chloride (75%) 0.80
6 Glyceryl stearate 1.00
7 Dimethicone (10000cs) 0.20
8 Aminopropyl dimethicone 0.10
9 Methylparaben 0.10
10 Citric acid 0.10
11 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1 to 8 were heated to about 80 ° C. and dissolved uniformly (part A). In another container 9-11 were heated to about 80 ° C. and dissolved uniformly (part B). B part was gradually added to part A and mixed uniformly.

Example 51 Leave-on treatment A leave-on treatment (for hair) having the following formulation was prepared. This leave-on treatment (for hair) was capable of imparting a soft and slippery feel to the hair with a moist feel. Moreover, stability was also favorable.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 0.50
2 Diethyl sebacate 1.00
3 Myristyl alcohol 5.00
4 Behenyl alcohol 1.00
5 Oleyl alcohol 1.00
6 Dimethylpropylamide stearate 2.00
7 Cocoamphoacetate Na (30%) 2.00
8 Glyceryl stearate 0.40
9 Myristic acid 0.60
10 Phenoxyethanol 0.40
11 Lactic acid 0.60
12 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1 to 10 were heated to about 80 ° C. and dissolved (part A). In another container 11 and 12, were heated to about 80 ° C. and dissolved (Part B). Part B was gradually added to part A and mixed uniformly.

Example 52 Leave-on treatment A leave-on treatment (for hair) having the following formulation was prepared. This leave-on treatment (for hair) was capable of imparting a soft and slippery feel to the hair with a moist feel. Moreover, stability was also favorable.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 2 0.50
2 Isopropyl palmitate 4.00
3 Cetanol 5.00
4 Steertrimonium chloride (63%) 3.20
5 Behentrimonium chloride (80%) 1.00
6 Squalane 1.00
7 Glycerin 1.00
8 Methylparaben 0.10
9 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1 to 7 were heated to about 80 ° C. and dissolved (Part A). In another container 8, 9 were taken and heated to about 80 ° C. to dissolve (Part B). Part B was gradually added to part A and mixed uniformly.

Example 53 Hair Essence A hair essence having the following formulation was prepared. This hair essence was refreshing and non-sticky and could give the hair a soft and slippery feel.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 0.50
2 Diethyl sebacate 1.00
3 Cetanol 1.00
4 Steartrimonium chloride (63%) 0.80
5 Zicococomonium chloride (75%) 2.80
6 Solveste tetraoleate-60 1.00
7 PEG-40 hydrogenated castor oil 0.20
8 Methylparaben 0.10
9 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1 to 7 were heated to about 80 ° C. and dissolved (Part A). In another container 8, 9 were taken and heated to about 80 ° C. to dissolve (Part B). Part B was gradually added to part A and mixed uniformly.

Example 54 Rinse-in shampoo A rinse-in shampoo having the following formulation was prepared. This rinse-in shampoo was not sticky, gave a moist feeling to the hair, and was able to give a smooth finger passage.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 2 1.00
2 Cocamidopropyl betaine (30%) 20.00
3 Lauryl sulfate TEA (40%) 15.00
4 Cocamide DEA 2.00
5 Cocoa glutamate TEA (30%) 30.00
6 Ethylene glycol distearate 1.20
7 Dimethicone (10000cs) 0.10
8 Aminopropyl dimethicone 0.10
9 Polyquaternium-10 1.60
10 Polyquaternium-7 1.60
11 Stearyl trimonium bromide (70%) 0.60
12 Phenoxyethanol 0.20
13 Methylparaben 0.20
14 Sodium benzoate 0.40
15 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 9 to 11 and 15 were heated to about 80 ° C. and mixed with stirring. Next, no. No. 3 was added and stirred. Add 1, 2, 4 to 8 and stir and mix until uniform. 12-14 was added and dissolved.

Example 55 Anti-aging cream An anti-aging cream having the following formulation was prepared. This cream had good elongation and was excellent in the effect of imparting a moist feeling.

Component Blending amount (% by weight)
----------------------------------
A
Diester of Example 1 10.00
Cetyl octanoate 7.00
Batyl isostearate 2.00
PEG-60 glyceryl isostearate 1.50
Hydrogenated palm oil 3.70
Ceramide 2 0.10
Retinol 0.10
Oil-soluble chamomile extract 0.10
Ethylparaben 0.20
Stearyl alcohol 3.50
Glyceryl stearate (SE) 1.00
Steerless-6 1.50
Distearic acid PEG-8 1.00
Cetanol 1.00
Dimethicone 1.00
Cetyl dimethicone copolyol 0.50
Tocopherol 0.20
B
Nishi Healing Extract 0.05
C
Arbutin 0.50
Ascorbic acid 2-O-glucoside 0.50
EDTA-3Na 0.10
Polyglutamic acid (Ichimaru Falcos, Bio PGA solution) 0.10
(Eicosanedioic acid / tetradecanedioic acid) Polyglyceryl-10 Esters 1.00
Glycerin 4.00
Bisulfite Na 0.05
Methylparaben 0.10
Phenoxyethanol 0.10
BG 6.00
Hydroxide K Appropriate amount of purified water Total amount of 100 ----------------------------------
(Production method)
A was heated to about 80 ° C. and dissolved uniformly (part A). C was heated to about 80 ° C. and dissolved (part C). While stirring with a homomixer at about 80 ° C., part C was gradually added to part A, mixed uniformly after emulsification, cooled to about 40 ° C., B was added and mixed uniformly.

Example 56 Hair restorer A hair restorer having the following formulation was prepared. This hair restorer was able to prevent hair loss, dandruff and itching.

Component Blending amount (% by weight)
----------------------------------
Diester of Example 1 0.05
Diethyl sebacate 0.45
Menthol 0.10
Pepper tincture 0.50
Assembly extract 2.00
Ethanol 30.00
Preservative Appropriate amount of perfume Appropriate amount PPG-6 Decyltetradeceth-30 0.30
Purified water Total amount of 100 ----------------------------------
(Production method)
Each component was stirred and mixed uniformly.

Example 57 Acid hair dye (hair manicure)
An acid hair dye having the following formulation was prepared. This acidic hair dye was an acidic hair dye capable of imparting a good feel such as flexibility and slipperiness to the hair by treating the hair.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 2.00
2 N-methylpyrrolidone 15.00
3 Benzyl alcohol 8.00
4 Citric acid 1.00
5 Brown 201 0.13
6 Black 401 0.05
7 Purified water Total amount of 100 --------------------------------
(Preparation method)
Each component was mixed uniformly.

Example 58 Perm Agent A perm agent having the following formulation was prepared. This permanent agent was a permanent agent that gave hair a feeling of slipping and softness when applied to the hair.

(1 liquid)
Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 1.00
2 Polyquaternium-22 2.00
3 Monoethanolamine 1.00
4 Ammonia water (28%) 1.00
5 PEG-50 hydrogenated castor oil 0.20
6 Ammonium bicarbonate 2.00
7 Phosphoric acid 2Na 0.50
8 Ammonium thioglycolate aqueous solution (50%) 11.50
9 Cysteine 1.50
10 EDTA-4Na 0.15
11 Hydroxide Na 0.25
12 Polyquaternium-10 0.10
13 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. No. 13 in the majority of No. 13 11 is dissolved and then No. 11 is dissolved. No. 12 was added in small portions and dissolved. 8-10 were added and dissolved (part A). No. in a separate container. Take the rest of 13 6 and 7 were added, and it heated and dissolved (part B). No. in a separate container. 1-5 was added, and it heated and melt | dissolved in about 50 degreeC (C part). Part B was added to part A and mixed uniformly, then part C was gradually added and mixed uniformly.

(2 liquids)
Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 0.50
2 Sodium benzoate 0.20
3 Edetic acid 2Na 0.10
4 Diammonium phosphate 0.10
5 Emmacol TS-703 (Sanei Chemical) 2.00
6 Stearyltrimonium chloride (50%) 2.00
7 Na bromate 10.00
8 Emmacol NZ (Sanei Chemical) 4.00
9 Ores-20 3.00
10 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. Take most of 10 and heat to about 60 ° C. No. 1 to 3 were added and dissolved. 4 was added and dissolved. Then No. No. 5 and 6 were added, and the mixture was heated and dissolved. 7-9 was added and made uniform. The remaining No. 10 was added, mixed uniformly and cooled.

Example 59 Sunscreen Cosmetic A sunscreen cosmetic having the following formulation was prepared. This sunscreen cosmetic did not float white and had a high UV protection effect.

Component Blending amount (% by weight)
--------------------------------
A
Quaternium-18 Hectorite 1.00
B
Cyclomethicone
13.70
Diphenyl dimethicone 7.00
Diester of Example 1 2.00
Dimethicone copolyol 5.50
YOFCO MAS (Nippon Seika) 1.00
C
Silicone-treated fine particle titanium oxide 3.90
Silicone-treated zinc oxide 2.10
D
Stearic acid Al 0.70
Hydroxide Al 0.50
Isononyl isononanoate 2.50
Isodecyl neopentanoate 2.50
E
Trimethylsiloxysilicate 1.20
Dimethicone 0.80
Meticon 0.10
Stearyl glycyrrhetinate 0.02
Sorbitan sesquioleate 2.00
Tocopherol 0.02
F
Na chloride 1.00
Methylparaben 0.15
Purified water Total amount of 100 --------------------------------
(Production method)
Add A to B and stir. Further, C is added and dispersed using a roller mill. D is heated and melted and added to the mixture of A, B, and C, and E is further added to about 70 ° C. F is warmed and emulsified gradually with stirring into a mixture of A to E. Cool with stirring and stop stirring at 40-35 ° C. and let stand.

Example 60 Bath agent (bubble bath)
A bath preparation having the following formulation was prepared. This bath preparation has effects such as moisturizing skin and improving skin gloss.

Component Blending amount (% by weight)
--------------------------------
A
(C12, 13) Palace-3 sulfate Na 5.00
Cocamide DEA 2.00
Sulfosuccinic acid (C12-14) Palace-2Na 2.00
1,3-butylene glycol 2.00
Diester of Example 2 1.00
PEG-20 glyceryl triisostearate 1.00
B
Citric acid 0.05
Sodium benzoate 0.20
Blue No.1 Trace yellow No.4 Trace C
Purified water Total amount of 100 --------------------------------
(Production method)
A is dissolved in a part of C to make it uniform. Add the remaining C and B and knead well.

Example 61 Hair Wax A hair wax having the following formulation was prepared. When applied to the hair, this hair wax is glossy, non-sticky, does not disperse even if it moves, has high adhesion, has a feeling of hair bundle, and has excellent hair style durability.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 2 4.00
2 Candelilla wax 2.00
3 Cetanol 8.00
4 Mineral oil 18.00
5 Trioctanoin 4.00
6 Microcrystalline wax 2.00
7 Diethyl sebacate 2.00
8 Dimethicone (100cs) 2.00
9 Laureth-2 2.00
10 Glyceryl stearate 3.00
11 PEG-40 hydrogenated castor oil 2.00
12 Polyglyceryl diisostearate-3 2.00
13 Glycerin 6.00
14 1,3-butylene glycol 4.00
15 Phenoxyethanol 0.60
16 Methylparaben 0.20
17 Alcox E-240 (Meisei Chemical Industry) 0.20
18 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1 to 14 were heated to about 80 ° C. and dissolved (part A). Next, no. 15-18 was heated to about 80 ° C. and dissolved (part B). While stirring Part B into Part A, it was gradually added and dissolved uniformly.

Example 62 Liquid Face Wash A liquid face wash having the following formulation was prepared. This liquid cleanser was able to give the skin a moist and smooth slipperiness.

Component Blending amount (% by weight)
--------------------------------
1 Lauroyl sarcosine Na 12.00
2 Myristoyl methyl taurine Na 2.00
3 Isethionate Na 1.00
4 Polyglyceryl laurate-6 2.00
5 Cocamide DEA 2.00
6 Sorbitol 8.00
7 PEG-30 4.00
8 1,3-butylene glycol 8.00
9 Diester of Example 1 2.00
10 Glycerin 5.00
11 Phenoxyethanol 0.80
12 (HEMA glucoside / ethyltrimonium methacrylate methacrylate)
Copolymer (10%) (Nippon Seika) 1.00
13 Purified water Total amount of 100 --------------------------------
(Production method)
No. 3 and 10 were heated to about 80 ° C. and dissolved (part A). No. in part A 1, 2, 4-9, 11-13 were added, heated to about 80 ° C. and uniformly dissolved, and then cooled.

Example 63 Body Shampoo A body shampoo having the following formulation was prepared. This body shampoo was able to give the skin a moist and smooth slipperiness.

Component Blending amount (% by weight)
--------------------------------
1 (HEMA glucoside / ethyltrimonium methacrylate methacrylate)
Copolymer (10%) (Nippon Seika) 2.00
2 Cocoyl Methyl Taurine Na 10.00
3 Lauroyl hydrolyzed silk Na 6.00
4 Lauroylmethylalanine Na 10.00
5 Cocoamphoacetate Na (30%) 4.00
6 Cocamidopropyl betaine (30%) 10.00
7 Cocamide DEA 3.00
8 Diester of Example 1 3.00
9 1,3-butylene glycol 5.00
10 Methylparaben 0.20
11 Purified water Total amount of 100 --------------------------------
(Production method)
No. 1 and a part of No. 11 were heated at about 80 ° C. and mixed uniformly (part A). No. 2-No. 10. The remaining 11 was heated at about 80 ° C. and mixed uniformly (Part B). While stirring, part A was gradually added to part B and mixed uniformly.

Example 64 Body Shampoo A body shampoo having the following formulation was prepared. This body shampoo was able to give the skin a moist and smooth slipperiness.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 2 0.50
2 CETEARETH-60 myristyl glycol 2.00
3 DEA laurate (1: 1 type) 5.00
4 Propylparaben 0.10
5 Methylparaben 0.20
6 Potassium soap base solution 40.00
7 Lauroylmethylalanine Na (30%) 10.00
8 Lactic acid 0.70
9 Purified water Total amount of 100 --------------------------------
(Production method)
No. 1-No. 5 was heated at about 70 ° C. and mixed uniformly (part A).
No. No. 8 9 was dissolved in part (B part). While stirring, No. 6, no. 7, no. The remainder of 9 and part B were gradually added and mixed uniformly.

Example 65 Body Shampoo A body shampoo having the following formulation was prepared. This body shampoo was able to give the skin a moist and smooth slipperiness.

Component Blending amount (% by weight)
--------------------------------
1 (HEMA glucoside / ethyltrimonium methacrylate methacrylate)
Copolymer (10%) (Nippon Seika) 2.00
2 Lauryl phosphate 20.00
3 Cocamidopropyl betaine (30%) 10.00
4 Lauroylmethylalanine Na 6.00
5 Cocamide DEA 2.00
6 Diester of Example 1 2.00
7 Distearic acid PEG-150 1.00
8 Glycerin 4.00
9 Sodium benzoate 0.40
10 Phenoxyethanol 0.20
11 Purified water Total amount of 100 --------------------------------
(Production method)
No. 1 and a part of No. 11 were heated at about 80 ° C. and mixed uniformly (part A). No. 2-No. 10. The remaining 11 was heated at about 80 ° C. and mixed uniformly (Part B). While stirring, part A was gradually added to part B and mixed uniformly.

Example 66 Face Wash Liquid A face wash liquid having the following formulation was prepared. This face-washing liquid was able to impart a moist feeling and a smooth slipperiness to the skin.

Component Blending amount (% by weight)
--------------------------------
Lipidure PMB (Japanese fat) 1.00
Diester of Example 1 1.00
Dipotassium glycyrrhizinate 0.05
Palm oil fatty acid diethanolamide 4.00
N-coconut oil fatty acid acyl-L-glutamic acid triethanolamine 1.50
Palm oil fatty acid amidopropyl betaine 8.10
N-coconut oil fatty acid acyl-DL-alanine triethanolamine 1.50
Preservative Appropriate amount Sodium monohydrogen phosphate anhydrous 1.00
Citric acid 0.15
Purified water Total amount of 100 --------------------------------
(Production method)
Warm to 40-50 ° C. and stir to make uniform.

Example 67 Face-wash foam A face-wash foam having the following formulation was prepared. This facial cleansing foam was able to give the skin a moist feeling and a smooth slipperiness.

Component Blending amount (% by weight)
--------------------------------
1 (coconut fatty acid / hydrogenated beef tallow fatty acid) glutamic acid Na 20.00
2 1,3-butylene glycol 14.00
3 Plandool-H (Nippon Seika) 1.00
4 PEG-8 5.00
5 PEG-30 10.00
6 Lauric acid diethanolamide 2.00
7 Propylparaben 0.10
8 Methylparaben 0.20
9 Lipidure PMB (Japanese fats and oils) 1.00
10 Crystalline cellulose 10.00
11 Diester of Example 1 5.00
12 Tocopherol 0.20
13 Purified water Total amount of 100 --------------------------------
(Production method)
No. 1 to 8 and 11 are heated to about 80 ° C. and dissolved. No. after dissolution Add 12 and 13 and dissolve. While stirring at about 60 ° C., no. Add 9, 10 and cool to about 40 ° C.

Example 68 Soap A soap having the following formulation was prepared. This soap was able to give the skin a moist feeling and a smooth slipperiness.

Component Blending amount (% by weight)
--------------------------------
Soken base Amount to be 100 in total Lauric acid 5.00
1,3-butylene glycol 3.00
Diester of Example 1 5.00
Plandool-H (Nippon Seika) 0.05
Titanium oxide 1.00
Etidronic acid 0.10
Edetate 0.10
Yellow No. 205 Trace --------------------------------
(Production method)
All components are dissolved by heating to 80 ° C., cooled with stirring, poured into molds and left to stand.

Example 69 Face Wash A face wash having the following formulation was prepared. This facial cleanser was able to give the skin a moist and smooth slipperiness.

Component Blending amount (% by weight)
--------------------------------
A
Diester of Example 1 0.50
Plandool-H (Nippon Seika) 0.20
Jojoba oil 0.10
Squalane 0.10
Cocamide DEA 2.00
Lauramide DEA 3.00
Tocopherol 0.20
Propylparaben 0.10
B
Distearate glycol 1.00
Lauroylmethylalanine Na (30%) 10.00
Coconut fatty acid K, myristic acid K (40%) 40.00
BG 3.50
1,5-pentanediol 0.50
1,2-hexanediol 0.30
PEG-20 5.00
PEG-400 5.00
Citric acid 0.50
Methylparaben 0.20
CETEARETH-60 myristyl glycol 2.00
Purified water Total amount of 100 --------------------------------
(Production method)
A was heated to about 80 ° C. and dissolved. B was heated to about 80 ° C. and dissolved. B was added to A with stirring and emulsified, and then cooled to about 40 ° C.

Example 70 Moisturizing lotion A moisturizing lotion having the following formulation was prepared. This moisturizing lotion was excellent in the feeling of use and moisturizing, kept the skin soft and fresh, smooth and moist, and these effects lasted for a long time.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 2.00
2 (Eicosanedioic acid / Tetradecanedioic acid) Polyglyceryl-10 Esters 1.00
3 BG 1.00
4 Glycerin 2.00
5 Citric acid 0.01
6 Na citrate 0.10
7 Ubiquinone 0.03
8 IOTG (Japan Seika) 0.03
9 Tetraoleic acid Solves-60 0.12
10 PEG-60 hydrogenated castor oil 0.03
11 PEG-30 glyceryl isostearate 0.03
12 Methylparaben 0.20
13 Fragrance
14 Ethanol 7.00
15 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1-6 are No. 15 and stirred and mixed uniformly (part A). Next, no. Nos. 7 to 13 14 (part B). A part was added to part B with stirring to make it uniform.

Example 71 Body soap A body soap having the following formulation was prepared. The body soap can give a moist and smooth feeling to the skin.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 0.50
2 Potassium soap base solution 40.00
3 Lauroylmethylalanine Na (30%) 10.00
4 Lauramide DEA 5.00
5 Ethylene glycol distearate 1.50
6 BG 5.00
7 Propylparaben 0.10
8 Methylparaben 0.20
9 Lactic acid 0.70
10 Purified water Total amount of 100 --------------------------------
(Production method)
No. 1-No. 10 was dissolved by heating at about 80 ° C. and cooled with stirring.

Example 72 Styling Gel A styling gel having the following formulation was prepared. When applied to hair, this styling gel was not sticky, did not move even when it was applied, and had high hair adhesion due to its high adhesion, and had excellent hairstyle durability.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 1.00
2 Diethoxyethyl succinate 2.00
3 STRUCTURE 2001 (made by NSC Japan) 7.00
4 TEA (50%) 3.00
5 AMPHOMER SH-10 (made by NSC Japan) 3.00
6 Ethanol (95%) 1.00
7 Methylisothiazolinone 0.01
8 Glycolic acid
9 TEA appropriate amount
10 Water Total amount of 100 --------------------------------
(Preparation method)
No. 1, no. 2, No. 7 and No. 10 are heated to about 60 ° C. and dissolved. Furthermore, no. 3 was added and dispersed, then No. 4 was added to increase the viscosity, and the mixture was cooled to 40 ° C. (Part A). No. 5, no. 6 is mixed uniformly, added to part A, and mixed uniformly. No. 8 or No. 9 to adjust the pH to 7.2-7.5.

Example 73 Hair Essence A hair essence having the following formulation was prepared. This hair essence was refreshing and non-sticky and could give the hair a soft and slippery feel.

Component Blending amount (% by weight)
--------------------------------
A
Diester of Example 1 0.50
Plandool-H (Nippon Seika) 0.50
Diethyl sebacate 0.50
Diisopropyl sebacate 0.50
Isodecyl neopentanoate 0.50
Cetanol 1.00
Behentrimonium chloride (80%) 0.60
Distearyldimonium chloride (75%) 2.80
Tetraoleic acid Solves-60 1.00
PEG-40 hydrogenated castor oil 0.20
B
Carbomer liquid (2%) 1.00
Xanthan gum solution (2%) 1.00
Citric acid appropriate amount Na citrate appropriate amount methylparaben 0.10
Phenoxyethanol 0.10
Purified water Total amount to be 100 in total --------------------------------
(Preparation method)
A was heated to about 80 ° C. to dissolve (A). B was put in another container and dissolved by heating to about 80 ° C. (B). B was gradually added to A and mixed uniformly.

Example 74 Hair foam A hair foam having the following formulation was prepared. This hair foam has a good feeling of use and a natural setting property, and provides an improved feel such as imparting gloss and moisture to the hair.

Component Blending amount (% by weight)
--------------------------------
(Stock solution formulation)
A
Diester of Example 1 2.00
Plandool-G (Nippon Seika) 3.00
Isopropyl palmitate 0.50
Isopropyl myristate 0.50
Cyclomethicone 0.40
Dimethicone
0.20
Aminopropyl dimethicone 0.20
Dimethicone polyol 0.20
B
Behentrimonium chloride 0.20
Laureth-2, -4, -9, -23 Appropriate amount Polyglyceryl oleate-2 0.20
Glycerin 3.00
C
(Acrylates / stearyl acrylate / ethylamine oxide methacrylate)
Copolymer (50%) 2.00
Fragrance 0.10
Ethanol 15.00
Phenoxyethanol Appropriate amount Methylparaben Appropriate amount Purified water Total amount of 100 (filling formula)
Stock solution 50.00
LPG 50.00
--------------------------------
(Preparation method)
Add A to B lysate and mix uniformly. C was added and mixed, and after filling this can into a can, gas was filled.

Example 75 Hair Foam A hair foam having the following formulation was prepared. This hair foam has a good feeling of use and a light natural setability, and provides an improved feel such as imparting gloss and moisture to the hair.

Component Blending amount (% by weight)
--------------------------------
(Stock solution formulation)
A
Diester of Example 1 1.00
Plandool-H (Nippon Seika) 1.00
LUSPLAN DD-IS (Nippon Seika) 1.00
Hydrogenated polybutene 0.20
Cetanol 1.50
Beeswax 1.00
Octenyl succinate corn starch 0.20
Dimethicone 0.10
Dimethicone polyol 0.30
Myristic acid 2.00
Triethanolamine appropriate amount PEG-hydrogenated castor oil 0.20
PEG-sorbitan cocoate 0.20
Behentrimonium chloride 0.20
PEG 3.00
Ethanol 15.00
Phenoxyethanol Appropriate amount of propylparaben Appropriate amount of methylparaben Appropriate amount of purified water Amount B totaling 100 in total
Fragrance 0.10
(Filling prescription)
Stock solution 50.00
LPG 50.00
--------------------------------
(Preparation method)
A was mixed according to a conventional method, and B was added. After filling this stock solution into a can, it was filled with gas.

Example 76 Hair Spray A hair spray having the following formulation was prepared. This hair spray has a good feeling of use and setability, and gives an improved feel such as imparting gloss and moisture to the hair.

Component Blending amount (% by weight)
--------------------------------
(Stock solution formulation)
A
Diester of Example 1 2.00
Plandool-G (Nippon Seika) 1.00
LUSPLAN DD-DA5 (Nippon Seika) 1.80
Hydrogenated rosin triglyceride 0.20
B
PEG hydrogenated castor oil 0.02
C
Fragrance 0.05
Ethanol (anhydrous) A total amount of 100 (filling formula)
Stock solution 55.00
LPG 45.00
--------------------------------
(Preparation method)
Add B to A. C was added and mixed, and after filling this can into a can, gas was filled.

Example 77 Hair mist Hair mist having the following formulation was prepared. This hair mist was not sticky, had a light setting property, and was able to impart a smooth touch and a smooth feel to the hair.

Component Blending amount (% by weight)
--------------------------------
Diester of Example 1 0.20
Plandool-H (Nippon Seika) 0.30
SUCRAPH AG-8 (Nippon Seika) 0.20
Dimethicone 0.20
Cetrimonium chloride (30%) 4.00
Ethanol 8.00
Purified water Total amount of 100 --------------------------------
(Preparation method)
Each component was stirred and mixed uniformly.

Example 78 Hand Cream A hand cream having the following formulation was prepared. This hand cream was non-sticky and water-repellent hand cream.

Component Blending amount (% by weight)
--------------------------------
1 Plandool-G (Nippon Seika) 0.30
2 Silwax S (Nippon Seika) 4.00
3 Hydrogenated lecithin 1.00
4 Behenyl alcohol 2.50
5 CIO (Japan Seika) 3.00
6 Diester of Example 1. 3.70
7 Propylparaben 0.20
8 Dimethicone 4.00
9 BG 5.00
10 Methylparaben 0.20
11 Xanthan gum (2% aqueous solution) 15.00
12 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 2, no. No. 8 was dissolved and No. 8 was dissolved. 1, no. Add 4-7 and warm to about 70 ° C. (A). No. 11 No. Dissolve in part of 12 to obtain a viscous liquid (B). No. 3, no. 9, no. 10, no. Add the remainder of 12 and warm to about 70 ° C. to dissolve (C). C is added to A 1 with stirring, and the mixture is stirred and mixed with a homomixer for about 3 minutes (D). Add B to D and mix evenly, then cool to about 40 ° C.

Example 79 Hair Color Shampoo A hair color shampoo having the following formulation was prepared. This shampoo for hair color suppresses discoloration of the hair color, and provides a touch improvement such as glossiness and moisturization and a lasting effect.

Component Blending amount (% by weight)
--------------------------------
1 (HEMA glucoside / ethyltrimonium methacrylate methacrylate)
Copolymer (10%) (Nippon Seika) 4.00
2 Cocoyl Methyl Taurine Na (30%) 15.00
3 Olefin (C14-16) sulfonic acid Na (36%) 13.00
4 Sodium cocoamphoacetate (30%) 8.00
5 PPG-12-PEG-50 Lanolin 2.50
6 Cocoyl glutamic acid (30%) 7.00
7 Polyquaternium-10 1.00
8 Lauramidopropylhydroxysultain / water 4.00
9 PEG-20 hydrogenated castor oil 2.00
10 Sunflower Ceramide (LABORATORIES SEROBIOLOGIQUES) 0.50
11 Proticute U Alpha (Ichimaru Falcos) 0.50
12 Etidronic acid 0.20
13 PG 0.20
14 Diester of Example 1 0.05
15 Methylparaben 0.20
16 Phenoxyethanol 0.20
17 Purified water Total amount of 100 ------------------------------
(Preparation method)
No. No. 17 After adding 7 and stirring, warm to about 80 ° C. to dissolve (A). In another container 13 is weighed and 14, no. No. 15 was added and blended. Add 6 and warm to about 80 ° C. to dissolve (B). B is added to A. 2-No. Add 5 in order and stir uniformly (C). In another container 1, no. 8-No. 10 is weighed and dissolved at about 80 ° C. (D). While heating to about 80 ° C., D was added to C, and the mixture was stirred and dissolved uniformly. 11, no. 12, no. After adding 16 and stirring well, it is cooled to room temperature and adjusted to pH 5.5 to 6.0.

Example 80 Pre-shave lotion A pre-shave lotion having the following formulation was prepared. This pre-shave lotion has the effect of making the skin smooth.

Component Blending amount (% by weight)
--------------------------------
A
Diester of Example 1 0.10
Citric acid 0.05
Zinc phenol sulfonate 0.20
PEG-60 hydrogenated castor oil 0.10
Glycyrrhizic acid 2K 0.05
Purified water Amount B totaling 100
Ethanol 30.00
Tocopherol 0.01
Methylparaben 0.15
--------------------------------
(Preparation method)
Both A and B are dissolved at room temperature, and B is gradually added to A with stirring to make it uniform.

Example 81 After Shave Lotion After shave lotion having the following formulation was prepared. This after-shave lotion has the effect of making the skin smooth.

Component Blending amount (% by weight)
--------------------------------
A
Diester of Example 2 0.10
Malic acid 0.10
Hyaluronic acid Na 0.01
Zinc phenol sulfonate 0.20
PEG-60 hydrogenated castor oil 0.20
Glycyrrhizic acid 2K 0.05
Vitamin B6 hydrochloride 0.10
Purified water Amount B totaling 100
Ethanol 30.00
Tocopherol 0.01
Menthol 0.01
Methylparaben 0.15
--------------------------------
(Preparation method)
Both A and B are dissolved at room temperature, and B is gradually added to A with stirring to make it uniform.

Example 82 Carmine lotion A carmine lotion having the following formulation was prepared. This carmine lotion has the effect of making the skin smooth.

Component Blending amount (% by weight)
--------------------------------
A
Calamine 0.40
Kaolin 4.00
Mg carbonate 0.10
Purified water 20.00
B
Diester of Example 1 0.20
1,3-butylene glycol 2.00
Allantoin 0.10
Purified water Amount C totaling 100
Ethanol 20.00
Canful 0.05
Methylparaben 0.20
--------------------------------
(Preparation method)
A is dispersed. Both B and C are dissolved at room temperature, C is gradually added to B with stirring, and A is gradually added with stirring to make it uniform.

Example 83 Deodorant Lotion A deodorant lotion having the following formulation was prepared. This deodorant lotion has the effect of making the skin smooth.

Component Blending amount (% by weight)
--------------------------------
A
Purified water Total amount of 100 (styrene / DVB) copolymer 0.20
Tea dry distillation solution 0.50
Benzalkonium chloride 0.05
Na chloride 0.10
Carboxymethyl chitin 0.02
B
Diester of Example 1 0.10
Denatured alcohol 50.00
Methylparaben 0.20
--------------------------------
(Preparation method)
Both A and B are dissolved at room temperature, and B is gradually added to A with stirring to make it uniform.

Example 84 Deodorant (Antiperspirant)
A deodorant (antiperspirant) having the following formulation was prepared. This deodorant has the effect of making the skin smooth.

Component Blending amount (% by weight)
--------------------------------
A
Diester of Example 1 0.20
Purified water Amount that totals 100 Methylparaben 0.10
Na chloride 0.01
Citric acid 0.05
Na citrate 0.05
Laureth-21 0.10
Benzalkonium chloride 0.05
Chlorhydroxyaluminum 0.20
B
Denatured alcohol 40.00
Propylparaben 0.50
Isopropyl methylphenol 0.50
--------------------------------
(Preparation method)
Both A and B are dissolved at room temperature, and B is gradually added to A with stirring to make it uniform.

Example 85 Cleansing Gel A cleansing gel having the following formulation was prepared. Since this cleansing gel is excellent in solubility, it can be easily removed such as foundation and make-up, and effects such as imparting a refreshing feel can be obtained.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 15.00
2 Plandool-H (Nippon Seika) 2.00
3 Bellpole DC-30 (Nippon Seika) 2.00
4 LUSPLAN DD-IS (Nippon Seika) 15.00
5 PEG-25 hydrogenated castor oil 20.00
6 Glycerin 16.00
7 BG 5.00
8 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1-No. 7 is weighed and dissolved by heating to about 80 ° C. (A). No. 8 is weighed and heated to about 80 ° C. (B). While stirring, gradually add B to A, and cool to 40 ° C. after emulsification.

Example 86 Moisture Pack A moisture pack having the following formulation was prepared. This moist chair pack enhances the moisturizing effect, softens the skin, gives a moist feeling, and provides an excellent cleaning action.

Component Blending amount (% by weight)
--------------------------------
A
Polyvinyl alcohol 13.00
1,3-butylene glycol 3.00
Alginic acid K 0.50
(Styrene / Vinylpyrrolidone) Copolymer 1.50
B
Plandool-G (Nippon Seika) 0.30
Diester of Example 1 0.20
PCA Glyceres-25 isostearate-25 1.50
Denatured alcohol 8.00
PEG / PPG-5 / 30 copolymer 1.00
Ores-10 phosphate DEA 1.00
Glycyrrhizic acid 2K 0.05
Tocopherol 0.10
Methylparaben 0.20
Hyaluronic acid Na 0.05
Na chloride 0.30
Purified water Total amount of 100 --------------------------------
(Preparation method)
A is warmed and swollen at 50 ° C. Slowly add B to A with stirring and mix uniformly. Cool with stirring, stop stirring at 30-25 ° C. and let stand.

Example 87 Lotion Toner lotion having the following formulation was prepared. This skin lotion was not sticky, gave a moist feeling, and was excellent in familiarity with the skin.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 2.00
2 Ascorbyl ethyl 1.00
3 DPG 2.00
4 BG 2.00
5 Citric acid 0.05
6 Na citrate 0.40
7 Ethanol 8.00
8 Phenoxyethanol 0.20
9 Methylparaben 0.10
10 EDTA-2Na 0.10
11 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 3-4, no. 7 to 9 were added and stirred and mixed uniformly (part A). Next, no. 2, no. 5-6, no. No. 10 11 (part B). In part A, part B and No. 1 was added with stirring to make it uniform.

Example 88 Cosmetic liquid The cosmetic liquid of the following prescription was prepared. This essence had a smooth feel while softening the skin and keeping the skin fresh and smooth.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 2 2.00
2 Ascorbyl ethyl 1.00
3 Glycyrrhizic acid 2K 0.10
4 DPG 2.00
5 BG 5.00
6 Citric acid 0.01
7 Na citrate 0.09
8 Tremoist-TP (Nippon Seika) 0.20
9 Ethanol 5.00
10 Phenoxyethanol 0.20
11 Methylparaben 0.10
12 EDTA-2Na 0.02
13 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 4-5, no. 7 to 11 were added and stirred and mixed uniformly (part A). Next, no. No. 13 in part No. 8 (part B). No. 2-3, no. 6-7, no. 12 for the remaining No. 13 (part C). In Part A, Part B, Part C and No. 1 was added with stirring to make it uniform.

Example 89 Skin Care Cream A skin care cream having the following formulation was prepared. This skin care cream was a cream excellent in the effect of imparting a moist feeling.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 2.00
2 Arbutin 3.00
3 Glycerin 3.00
4 Squalane 3.00
5 Jojoba oil 3.00
6 Palm kernel oil 3.10
7 Glyceryl stearate 2.30
8 PEG-60 glyceryl isostearate 1.40
9 Stearic acid PG (SE) 1.30
10 Stearyl alcohol 3.00
11 Behenyl alcohol 2.00
12 Dimethicone 1.50
13 Ethylparaben 0.10
14 Methylparaben 0.15
15 Citric acid 0.01
16 Na citrate 0.09
17 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 1-2, no. 13-17 was heated to about 80 degreeC and it was made to melt | dissolve uniformly (A part). Next, no. 3 to 12 were heated to about 80 ° C. and dissolved uniformly (part B). A part A was added to part B with stirring and emulsified, and then cooled.

Example 90 Body soap A body soap having the following formulation was prepared. The body soap can give a moist and smooth feeling to the skin.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 2.00
2 Potassium soap base solution (37%) 40.00
3 Laurylmethyl taurine Na 2.00
4 Glyceryl stearate (SE) 1.00
5 Palm kernel oil fatty acid DEA 2.00
6 PEG-8 2.00
7 Tremoist-TP (Nippon Seika) 0.05
8 Lactic acid 3.27
9 EDTA-2Na 0.05
10 Ethylparaben 0.10
11 Methylparaben 0.10
12 Phenoxyethanol 0.20
13 Purified water Total amount of 100 --------------------------------
(Production method)
No. 1-No. 13 was heated and dissolved at about 80 ° C. and cooled with stirring.

Example 91 Emulsion An emulsion having the following formulation was prepared. This emulsion was excellent in the effect of imparting a moist feeling.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 5.00
2 Squalane 8.00
3 IOTG (Japan Seika) 8.00
4 Cetyl dimethicone copolyol 1.00
5 Polyglyceryl diisostearate-3 0.80
6 Polysorbate 40 1.00
7 Glyceryl stearate 1.00
8 Solveste tetraoleate-60 1.00
9 Dimethicone (10cs) 4.00
10 Ethylparaben 0.10
11 Methylparaben 0.10
12 Phenoxyethanol 0.20
13 Hydrolyzed collagen 0.20
14 Hydrolyzed keratin 0.20
15 Carbomer 0.50
16 Hydroxide K 0.20
17 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 17 is a part of No. 17. 15 and stirring, No. 15 16 was added to obtain a viscous liquid (Part A). Next, no. 1, no. 11-12, the remaining No. 17 was heated to about 70 ° C. and dissolved (Part B). No. 2 to 10 were heated to about 70 ° C. and dissolved (part C). Part B is added to Part C with stirring and emulsified, and then cooled to about 50 ° C. 13-14 was added and stirred until uniform.

Example 92 Cleansing milk A cleansing milk having the following formulation was prepared. Since this cleansing milk is excellent in solubility, it has a good foundation and make-up, and has an effect of giving a refreshing feel.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 3.00
2 Neosolute-DE (Nippon Seika) 5.00
3 Stearic acid 0.50
4 Mineral oil 32.00
5 Seths-20 2.40
6 Triceteth-5 Phosphoric acid 3.60
7 Stearic acid PG (SE) 3.00
8 Propylparaben 0.10
9 Dimethicone 10.00
10 Carbomer 0.10
11 Hydroxide K 0.04
12 EDTA-2Na 0.05
13 Phenoxyethanol 0.20
14 Methylparaben 0.10
15 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 15 is a part of No. 15. No. 10 was added and stirred well. 11 was added to obtain a viscous liquid (Part A). No. 12-14, the remaining No. 15 was heated to about 70 ° C. and dissolved (Part B). No. 1 to 9 were heated to about 70 ° C. and dissolved (part C). After stirring and emulsifying part B while stirring part C, part A was added and cooled with stirring.

Example 93 Lipstick A lipstick having the following formulation was prepared. This lipstick was fresh and highly adhesive.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 4.00
2 Plandool-G (Nippon Seika) 27.50
3 LUSPLAN DD-DA7 (Nippon Seika) 8.00
4 YOFCO MAS (Nippon Seika) 3.00
5 Neosolute-DE (Nippon Seika) 5.00
6 CIO (Nippon Seika) 15.00
7 IOTG (Nippon Seika) 15.00
8 Cyclomethicone 5.00
9 Ceresin 9.00
10 Candelilla Row 5.00
11 Tocopherol 0.50
12 Iron oxide 1.00
13 Titanium oxide 1.00
14 Mica 1.00
--------------------------------
(Preparation method)
No. 1 to 14 was added and mixed uniformly with stirring at about 80 ° C., and then rapidly cooled.

Example 94 Nail Remover A nail remover having the following formulation was prepared. This nail remover was excellent in removing nail enamel and provided a moist feeling to the nails.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 50.00
2 CIO (Nippon Seika) 50.00
--------------------------------
(Preparation method)
No. 1-2 was added and mixed uniformly with stirring.

Example 94 Nail Remover A nail remover having the following formulation was prepared. This nail remover was excellent in removing nail enamel and suppressed whitening of nails.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 10.00
2 Butyl acetate 30.00
3 Tocopherol 0.05
4 Ethyl acetate Residual ---------------------------------
(Preparation method)
No. 1-4 were added and mixed uniformly with stirring.

Example 95 Hair mist Hair mist having the following formulation was prepared. This hair mist was not sticky, had a light setting property, and was able to impart a smooth touch and a smooth feel to the hair.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 2.00
2 Hydrolyzed keratin 2.00
3 Cetrimonium chloride (30%) 0.60
4 Glycerin 5.00
5 Phenoxyethanol 0.20
6 Polyquaternium-6 0.80
7 Betaine 0.80
8 Ethanol 20.00
9 Purified water Total amount of 100 --------------------------------
(Preparation method)
Each component was stirred and mixed uniformly.

Example 96 Leave-on treatment A leave-on treatment (for hair) having the following formulation was prepared. This leave-on treatment (for hair) was capable of imparting a soft and slippery feel to the hair with a moist feel. Moreover, stability was also favorable.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 2.00
2 Hydrolyzed keratin 2.00
3 Cetrimonium chloride (30%) 3.80
4 Sucraph AG-8 (Nippon Seika) 0.80
5 Glycerin 4.00
6 Phenoxyethanol 0.20
7 Polyquaternium-6 0.60
8 Polyquaternium-7 0.40
9 Ethanol 20.40
10 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 7, 8, and 10 were heated to about 80 ° C. and dissolved (part A). No. in part A No. 1-6 was added and evenly dissolved, but after cooling to about 40 ° C., No. 1 9 was added and stirred and mixed uniformly.

Example 97 Hair Essence A hair essence having the following formulation was prepared. This hair essence was able to impart a soft and slippery feel to the hair with a moist feel.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 5.00
2 Pentylene glycol 2.00
3 Phenoxyethanol 0.20
4 Stearyltrimonium chloride (64%) 4.60
5 Scroll AG-8 (Nippon Seika) 1.00
6 Dicocodimonium chloride (74%) 0.80
7 Lauramide DEA 1.00
8 PEG-60 hydrogenated castor oil 0.80
9 Castor oil 0.20
10 Ethanol 20.00
11 Polyquaternium-10 0.20
12 Purified water Total amount of 100 --------------------------------
(Preparation method)
No. 11 to 12 were heated to about 80 ° C. and dissolved (part A). No. in part A No. 1-8 were added and evenly dissolved, but after cooling to about 40 ° C., No. 1 9 to 10 was added and stirred and mixed uniformly.

Example 98 Hair mist Hair mist having the following formulation was prepared. This hair mist was not sticky, had a light setting property, and provided a moist feeling and suppleness.

Component Blending amount (% by weight)
--------------------------------
1 Diester of Example 1 5.00
2 Glycerin 5.00
3 Pentylene glycol 2.00
4 Behentrimonium chloride (80%) 0.60
5 Ethanol 20.00
6 Dimethiconepropyl PG betaine 1.00
7 Purified water Total amount of 100 --------------------------------
(Preparation method)
Each component was stirred and mixed uniformly.

  According to the present invention, it has both hydrophilic and lipophilic functions, is smooth to the touch, does not feel moist and sticky, has a good fit on the skin, and uses water that does not use a surfactant as a medium. Diesters that can be blended in cosmetics or skin external preparations that are excellent in aging and oxidation stability, and pH stability in an aqueous solution system, and cosmetics that have excellent usability and stability by containing the diesters Or a skin external preparation can be obtained.

Claims (5)

A cosmetic or external preparation for skin containing a diester of a dicarboxylic acid represented by Chemical Formula 1 and a polyoxyethylene monoalkyl ether represented by Chemical Formula 2.
(Chemical formula 1)
HO-CO-R1-CO-OH
(In the formula, R1 represents a linear or branched hydrocarbon group having 4 to 10 carbon atoms)
(Chemical formula 2)
R2- (OCH2CH2) n-OH
(Wherein R2 is a linear, branched or cyclic hydrocarbon group having 1 to 12 carbon atoms, and n represents an integer of 2 to 11)   The cosmetic or external skin preparation according to claim 1, wherein the dicarboxylic acid represented by Chemical Formula 1 is one or more selected from adipic acid, azelaic acid, sebacic acid, and dodecanedioic acid.   The cosmetic or external skin preparation according to claim 1, wherein the dicarboxylic acid represented by Chemical Formula 1 is adipic acid.   The cosmetic or external preparation for skin according to any one of claims 1 to 3, wherein R2 of the polyoxyethylene monoalkyl ether represented by Chemical formula 2 is a methyl group or an ethyl group.   The cosmetic or skin according to any one of claims 1 to 3, wherein the polyoxyethylene monoalkyl ether represented by Chemical Formula 2 is one or two selected from diethylene glycol monoethyl ether and triethylene glycol monoethyl ether. Topical agent.