JP2008285436A - Aerosol-spraying agent - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide an aerosol-spraying agent capable of maintaining a high refreshing feeling over a long period of time. <P>SOLUTION: This aerosol-spraying agent comprises a stock solution containing (A) ethanol and/or isopropopanol, (B) menthol, (C) a cool feeling agent other than the menthol, (D) a non-volatile silicone and (E) one or more kinds of perfumery components selected from the group consisting of linalol, geraniol, hydroxycitronellal and eucaliptol, and not essentially containing water, and a propellant. <P>COPYRIGHT: (C)2009,JPO&INPIT

Description

  The present invention relates to an aerosol spray.

  In order to give a refreshing feeling when an external preparation for skin is used, a cooling sensation agent such as menthol or camphor is widely used. However, only by blending these cooling sensates, a refreshing feeling can be obtained at the time of use, but there is a problem that the sustainability of the effect is inferior. In addition, when the cooling sensation agent is blended at a high concentration, there is a problem that only the cooling sensation during use becomes strong and a skin irritation sensation occurs.

  As an attempt to maintain a refreshing feeling, for example, Patent Document 1 proposes an aerosol composition containing a cooling sensation agent such as menthol, a polyhydric alcohol, ethanol, water and carbon dioxide. Patent Document 2 proposes an external preparation for skin containing ethanol and water as main solvents, a cooling sensation agent such as menthol, and a plant extract having a blood circulation promoting action.

  However, although these techniques maintain a refreshing feeling to some extent, a high refreshing feeling cannot be maintained for a long time.

JP 2003-286131 A JP 2001-181120 A

  This invention is made | formed in view of the said prior art, Comprising: It aims at providing the aerosol spray agent which can maintain a high refreshing feeling over a long time.

  That is, the present invention provides (A) ethanol and / or isopropanol, (B) menthol, (C) a cooling agent other than menthol, (D) non-volatile silicone, and (E) linalool, geraniol, hydroxycitronellal and The present invention relates to an aerosol spray agent comprising a stock solution containing at least one fragrance component selected from the group consisting of eucalyptol and containing substantially no water, and a propellant.

  When applied to the skin, the aerosol spray of the present invention gives a smooth feeling of use and has an effect of maintaining a high refreshing feeling for a long time without developing skin irritation.

  The aerosol spray agent of the present invention comprises a stock solution containing alcohols, a cooling sensation agent, a nonvolatile silicone, and a fragrance component, and a propellant.

  First, the stock solution used for the aerosol spray of the present invention will be described. The alcohol of component (A) used in the stock solution of the present invention is ethanol or isopropanol. These can be used singly or in appropriate combination of two.

  Although content of (A) component will not be specifically limited if the effect of this invention can be exhibited, from a viewpoint of providing a high refreshing feeling, 80 weight% or more in a stock solution is preferable and 90 weight% or more is more preferable. Further, from the viewpoint of containing an effective amount of other components, 99.5% by weight or less is preferable. Accordingly, the content of the component (A) is preferably 80 to 99.5% by weight in the stock solution, and more preferably 90 to 99.5% by weight.

  As the cooling sensation agent used in the present invention, a cooling sensation agent other than (B) component menthol and (C) component menthol is used. Examples of the cooling sensation agent other than menthol (C) include menthol derivatives such as menthyl glyceryl ether, menthyl lactate, menthol glycoside, camphor, mint oil, peppermint oil, eucalyptus oil, and the like. Of these, menthol derivatives are preferably used, and menthyl glyceryl ether is more preferably used.

  The content of the component (B) is not particularly limited as long as the effects of the present invention can be exhibited, but from the viewpoint of developing a refreshing feeling, 0.05% by weight or more in the stock solution is preferable, and 0.1% by weight or more is more preferable. Moreover, from a viewpoint of suppressing skin irritation, 4% by weight or less is preferable, and 2% by weight or less is more preferable. From these, the content of the component (B) is preferably 0.05 to 4% by weight, more preferably 0.1 to 2% by weight in the stock solution.

  (C) A component can also be used individually by 1 type or in mixture of 2 or more types as appropriate. The content is not particularly limited as long as the effects of the present invention can be exhibited, but from the viewpoint of expressing a refreshing feeling, 0.1% by weight or more in the stock solution is preferable, and 0.2% by weight or more is more preferable. Moreover, from a viewpoint of suppressing skin irritation, 10 weight% or less is preferable and 3 weight% or less is more preferable. Accordingly, the content of the component (C) is preferably 0.1 to 10% by weight in the stock solution, and more preferably 0.2 to 3% by weight.

  Examples of the non-volatile silicone of component (D) include amino-modified silicone derivatives such as aminoethylaminopropylsiloxane / dimethylsiloxane copolymer and trimethylsilylamodimethicone; alcohol-modified silicones such as dimethylsiloxane / methylstearoxysiloxane copolymer. Polyoxyalkylene-modified silicones such as poly (oxyethylene / oxypropylene) methylpolysiloxane copolymer and dimethylsiloxane / methyl (polyoxyethylene) siloxane copolymer; polyglycerin-modified such as polyglyceryl-3 / disiloxane / dimethicone Silicone; dimethylpolysiloxane, methylphenylpolysiloxane, etc. can be exemplified, aliphatic alcohol-modified silicone, epoxy-modified silicone, fluorine-modified silicone Perfluoroalkyl polyoxyalkylene-modified silicone, may be other modified silicones such as ammonium modified silicones. Of these, dimethylpolysiloxane and methylphenylpolysiloxane are preferable, and methylphenylpolysiloxane is more preferably used.

  (D) A component can also be used individually by 1 type or in mixture of 2 or more types as appropriate. The content is not particularly limited as long as the effects of the present invention can be exhibited, but from the viewpoint of usability, 0.1% by weight or more in the stock solution is preferable, and 1% by weight or more is more preferable. Moreover, from a viewpoint of suppressing stickiness, 15 weight% or less is preferable and 10 weight% or less is more preferable. Accordingly, the content of the component (D) is preferably 0.1 to 15% by weight in the stock solution, and more preferably 1 to 10% by weight.

  As the fragrance component of component (E), linalool, geraniol, hydroxycitronellal, or eucalyptol is used from the viewpoint of sustaining a refreshing feeling. These may be used alone or in appropriate combination of two or more.

  The content of the component (E) is not particularly limited as long as the effect of the present invention can be exhibited, but from the viewpoint of the refreshing feeling, 0.001% by weight or more in the stock solution is preferable, and 0.005% by weight or more is more preferable. . Moreover, from a viewpoint of suppressing that the fragrance of a fragrance | flavor becomes too strong, 1 weight% or less is preferable and 0.5 weight% or less is more preferable. Accordingly, the content of the component (E) is preferably 0.001 to 1% by weight in the stock solution, and more preferably 0.005 to 0.5% by weight.

  The aerosol spray stock solution of the present invention contains substantially no water from the viewpoint of compatibility with the propellant.

  In addition, it is desirable that the stock solution of the aerosol spray of the present invention does not contain powder components such as silicic anhydride, talc, and polyethylene from the viewpoint of suppressing clogging of valves and buttons.

  Furthermore, since it is desirable that the stock solution of the present invention does not contain water or powder, it is preferable that substantially no surfactant is contained.

  In the present invention, “substantially does not contain” means “does not contain water or surfactant separately”, and includes a small amount of water or surfactant contained in each compounding component. It does not exclude up to blending.

  In addition to the components described above, the aerosol spray stock solution of the present invention includes aluminum chloride, potassium aluminum sulfate, aluminum sulfate, aluminum acetate, chlorohydroxyaluminum, allantochlorochloroaluminum, para Antiperspirants such as zinc phenolsulfonate; bactericides such as benzalkonium chloride, benzethonium chloride, halocarban, trichlorocarbanilide, chlorhexidine hydrochloride, isopropylmethylphenol, triclosan, chlorhexidine gluconate, lysozyme chloride; zinc oxide, alkyl Deodorants such as diethanolamide, hydroxyapatite, tea extract, cyclodextrin derivatives; anti-inflammatory agents such as dipotassium glycyrrhizinate, allantoin, hinokitiol; Arbuti , Whitening ingredients such as ascorbic acid and derivatives thereof; plant extract extracts such as peonies, buttonpi, loquat and aloe; 1,3-butylene glycol, dipropylene glycol, 1,2-pentanediol, 1,2-hexanediol, 1 Polyhydric alcohols such as 1,2-octanediol; Thickening polymers such as carboxyvinyl polymer, hydroxyethyl cellulose, guar gum and xanthan gum; Higher alcohols such as cetyl alcohol and stearyl alcohol; Hydrocarbons such as liquid paraffin and squalane; Isopropyl myristate Fatty acid esters such as cetyl 2-ethylhexanoate; sequestering agents such as edetate, phosphoric acid and sodium polyphosphate; tocopherol and its derivatives, ascorbic acid and its derivatives, dibutylhydroxytoluene, May be blended phenoxyethanol, octoxyglycerin, an antiseptic component parabens etc., antioxidants such as sulfates.

  Next, the propellant used for the aerosol spray of the present invention will be described. The propellant used in the present invention is not particularly limited as long as it can be used as an aerosol in the high-pressure gas control method. Specific examples include liquefied petroleum gas, isobutane, dimethyl ether, and the like composed of low-boiling hydrocarbons having 4 or less carbon atoms such as propane and butane. Of these, liquefied petroleum gas or dimethyl ether is preferably used.

  You may use a propellant individually by 1 type or in mixture of 2 or more types as appropriate. The mixing ratio of the undiluted solution and the propellant in the aerosol spray is not particularly limited as long as the effect of the present invention is exhibited. The amount is preferably 1 to 9 parts by weight.

  In order to produce the aerosol spray of the present invention, it may be produced by a known method. For example, the aerosol container is filled with a solution in which each component to be blended in the stock solution is uniformly dispersed, and the container is filled with the aerosol valve. After clinching, a method of filling a specified amount of propellant from the stem and attaching a button suitable for the stem can be exemplified.

  Since the aerosol spray of the present invention can maintain a high refreshing feeling for a long time as described above, it is preferably used for deodorant spray, lotion spray, body spray, hair tonic spray, hair growth spray, etc. Can do.

  EXAMPLES Hereinafter, although this invention is demonstrated based on an Example, this invention is not limited at all by these Examples. In addition, unless otherwise specified, the blending amount represents% by weight.

(Selection of subjects)
The test was conducted by 66 males aged 20-39 years in a test room with a room temperature of 23-27 ° C. First, the lower part of the ears of the subject's neck was wiped with a wet towel to remove sebum and the like, and was allowed to stand quietly for 10 minutes. A 100 μL sample having a composition with different menthol concentrations shown in Table 1 was impregnated into a 2 × 2 cm ² non-woven fabric (trade name: TCF # 404WJ-M, manufactured by Nimura Chemical Co., Ltd.). A high-concentration refresher sample of Formula 2 was applied to the left lower neck ear, and the refreshing strength after 1, 3, 5, 7, and 10 minutes was determined. .

  In addition, since the refreshing sensation feels as tingling pain and burning when the degree becomes too strong, the evaluation is made with the same evaluation items as refreshing feeling, tingling pain and burning. Four-level evaluation was performed according to the following evaluation criteria, and the average value was adopted.

<Evaluation criteria>
I do not feel at all 0 points I feel faintly 1 point I feel clearly 2 points I feel unbearable 3 points

By changing the test implementation date, the low-concentration freshener sample of Formula 1 was placed on the left side, and the high-concentration freshener sample of Formula 2 was applied on the right side, and the same determination was made.
The average score of the refreshing feeling after 1, 3, 5, 7, and 10 minutes of each subject was calculated, and 39 subjects satisfying all the following criteria 1 to 3 were selected.

<Selection criteria>
1: The difference in the average score between the low-concentration freshener sample and the high-concentration freshener sample is 0.5 or more. 2: The average score of the high-concentration freshener sample is 0.5 or more. Meet the criteria of

(Sample adjustment)
After 40 parts by weight of a stock solution in which the components of Examples and Comparative Examples shown in Tables 2 and 3 were uniformly dispersed were filled in an aerosol container, the container was clinched with an aerosol valve, and then 60 parts by weight of liquefied petroleum gas was added. Each aerosol spray was prepared by filling from the stem and attaching a button suitable for the stem.

(Test Example 1: Evaluation of refreshing feeling and skin irritation)
Ten subjects selected above were randomly selected, and the lower neck ears of the subjects were wiped with a wet towel to remove sebum and the like, and were allowed to stand quietly for 10 minutes. Each aerosol sample shown in Tables 2 to 3 was placed on a skin of a 3 cm diameter cylindrical tube from the spraying part to the skin of the lower part of the neck and sprayed for 1 second. The strength of the refreshing feeling 10 minutes after the injection was evaluated in four stages according to the above evaluation criteria, the average value was adopted, and the following evaluation criteria were used. The results are also shown in Tables 2-3.

<Evaluation criteria>
A: Average score is 1.5 or more.
○: Average score is 1.0 or more and less than 1.5.
Δ: The average score is 0.5 or more and less than 1.0.
X: Average score is less than 0.5.

(Test Example 2: Evaluation of feeling of use)
Ten selected subjects were randomly selected, and each of the aerosol samples shown in Tables 2 to 3 was placed in a cylindrical tube having a diameter of 3 cm from the spraying part under the subject's eyelid and sprayed for 1 second. About the smooth use feeling under the armor immediately after application | coating, it determined by the following evaluation criteria. The results are also shown in Tables 2-3.

<Evaluation criteria>
A: Nine or more subjects answered that they would be free.
○: Reply when 6 to 8 subjects were free-flowing.
Δ: Answer that 3 to 5 subjects were free-flowing.
×: Answer that 2 or less of the subjects are free-flowing.

  From the results of Tables 2 and 3, it can be seen that the aerosol spray of the present invention maintains a high refreshing feeling for a long time. Moreover, it turns out that the aerosol spray agent of this invention provides the feeling of smooth use.

  Hereafter, the formulation example of the aerosol spray agent concerning this invention is shown. In addition, a compounding quantity is weight%.

(Formulation example 1: Deodorant spray)
<Undiluted solution>
Menthol 1.0
Menthyl glyceryl ether 1.0
Methylphenylpolysiloxane 1.0
Isopropylmethylphenol 0.1
Zinc paraphenol sulfonate 0.3
Geraniol 0.01
Ethanol residue
Total 100.0
<Propellant>
Liquefied petroleum gas 100.0
<Mixing ratio>
Stock solution / propellant = 40/60

(Formulation example 2: Deodorant spray)
<Undiluted solution>
Menthol 1.0
Menthyl glyceryl ether 1.0
Methylphenylpolysiloxane 1.0
Triclosan 0.2
Zinc paraphenol sulfonate 0.3
Geraniol 0.01
Linalool 0.01
Ethanol residue
Total 100.0
<Propellant>
Liquefied petroleum gas 70.0
Dimethyl ether 30.0
Total 100.0
<Mixing ratio>
Stock solution / propellant = 20/80

(Prescription Example 3: Hair Growth Spray)
<Undiluted solution>
Menthol 0.6
Menthyl glyceryl ether 1.0
1.3-Butylene glycol 3.0
Isopropylmethylphenol 0.1
Dl-α-tocopherol acetate 0.2
Geraniol 0.01
Linalool 0.01
Ethanol residue
Total 100.0
<Propellant>
Liquefied petroleum gas 100.0
<Mixing ratio>
Stock solution / propellant = 70/30

Claims (6)

An aerosol spray comprising a stock solution containing the following components (A) to (E) and substantially free of water and a propellant.
(A) Ethanol and / or isopropanol (B) Menthol (C) Cooling sensation other than menthol (D) Nonvolatile silicone (E) Linalool, Geraniol, Hydroxycitronellal and Eucalyptol Perfume ingredients above   The aerosol spray agent according to claim 1, wherein the component (C) is menthyl glyceryl ether.   The aerosol spray agent according to claim 1 or 2, wherein the component (D) is methylphenyl polysiloxane.   The aerosol spray agent according to any one of claims 1 to 3, wherein the stock solution contains substantially no surfactant.   The aerosol spray agent according to any one of claims 1 to 4, wherein the content of the component (A) in the stock solution is 80 to 99.5 wt%.   The aerosol spray agent according to any one of claims 1 to 5, wherein the propellant is liquefied petroleum gas and / or dimethyl ether.