JP2006314240A - Low-calorie sweetener inhibiting rise in blood-sugar level - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide low-calorie sweetener inhibiting rise in blood-sugar levels which inhibits rise in blood-sugar levels, having a function of regulating intestinal disorders and useful for persons having diabetes or obesity. <P>SOLUTION: The low-calorie sweetener inhibiting rise in blood-sugar levels comprises oligosaccharide, digestibility-resistant dietary fibers and high-sweetness sweetener, or further containing a sugar alcohol-containing sweetener composition, and food containing the above-mentioned materials. <P>COPYRIGHT: (C)2007,JPO&INPIT

Description

  The present invention relates to a low calorie sweetener composition that suppresses an increase in blood sugar level. More specifically, the present invention relates to a low-calorie sweetener composition characterized by containing an oligosaccharide, an indigestible dietary fiber and a high-intensity sweetener, or even a sugar alcohol and suppressing an increase in blood glucose level.

  As eating habits become richer, diseases caused by changes in lifestyle such as heart diseases represented by myocardial infarction, brain diseases represented by cerebral infarction, malignant tumors, and diabetes have become social problems. In particular, diabetes is considered to be important for prevention of illness because it is a serious disease. However, according to statistics from the Ministry of Health, Labor and Welfare in 2002, the total number of diabetics and those suspected of suffering (diabetes reserves) tends to increase year by year, reaching 16 million.

For diabetics and their reserves, dietary therapy based on food exchange tables is instructed and widely used, but it limits the total calorie intake. In particular, the use of sucrose, a sweetener, is extremely limited, and those who receive diet have a strong craving for sweetness. Diabetes mellitus is a disease that continues to have a high glucose concentration (blood glucose) in the blood (hyperglycemia). On the other hand, as a result of poor insulin secretion or low sensitivity to insulin, the hyperglycemic state becomes normal. Normally, it is believed that the diabetic condition worsens as the hyperglycemic state continues. Therefore, it is important for diabetic patients to control blood sugar in normal life. For this reason, foods that are difficult to produce a hyperglycemic state after meals and sweeteners that do not affect blood sugar are used in the diet of diabetic patients. Diabetes patients are prone to constipation due to continuation of a low-calorie diet and autonomic dysfunction known as a complication of diabetes, and a decrease in quality of life (QOL) is a problem. In order to solve this problem, a sweetener composition containing acesulfame potassium and fructooligosaccharide is disclosed. The composition is a sweetener composition having an intestinal regulating action and a good quality sweetness, and is described as being useful when used in foods that are conscious of diabetes, but suppresses an increase in blood sugar level. Is not disclosed (see Patent Document 1). On the other hand, a bowel movement improving composition containing water-soluble dietary fiber (such as indigestible dextrin), oligosaccharides, roasted cereals, tea polyphenols and lactic acid bacteria is disclosed. However, the composition is not a sweetener and does not disclose an effect on blood glucose level (see Patent Document 2).
Japanese Patent Laid-Open No. 2002-142709 JP 2004-155727 A

  As a treatment for those who are strongly suspected of having diabetes or its morbidity, weight control by caloric restriction is performed, but these diets are very painful and stressful. In order to alleviate these pains and stresses, low calorie does not cause an increase in blood sugar level, and when used in a meal, it prevents the increase in blood sugar level due to diet-derived components and post-meal hyperglycemia. A functional sweetener with high functionality is desired.

  As a result of intensive studies to solve the above problems, the present inventors have found that a composition containing an oligosaccharide, an indigestible dietary fiber and a high-intensity sweetener, or a sugar alcohol further has a blood sugar level when taken orally. Focusing on the fact that it has no effect, the present inventors have completed the sweetener composition of the present invention that improves the quality of life of diabetics and those suspected of being affected.

That is, the present invention includes the following inventions.
(1) A sweetener composition comprising an oligosaccharide, an indigestible dietary fiber, and a high-intensity sweetener that suppresses an increase in blood glucose level.
(2) A sweetener composition characterized by further containing a sugar alcohol in the composition according to (1) and suppressing an increase in blood sugar level.
(3) The sweetener composition according to any one of (1) to (2), wherein the oligosaccharide is a fructooligosaccharide.
(4) The sweetener composition according to (3), wherein the fructo-oligosaccharide is one or more selected from 1-kestose, nystose or 1-fructosyl nystose.
(5) The sweetener composition according to any one of (1) to (2), wherein the indigestible dietary fiber is at least one selected from reduced indigestible dextrin or indigestible dextrin.
(6) The sweetener composition according to any one of (1) to (2), wherein the high-intensity sweetener is one or more selected from sucralose or acesulfame potassium.
(7) The sweetener composition according to (2), wherein the sugar alcohol is at least one selected from reduced maltose starch syrup or erythritol.
(8) The sweetener according to (2), wherein the oligosaccharide is fructooligosaccharide, the indigestible dietary fiber is a reduced indigestible dextrin, the high-intensity sweetener is sucralose and / or acesulfame potassium, and the sugar alcohol is reduced maltose starch syrup. Composition.
(9) 5 to 90% by weight of fructooligosaccharide, 5 to 90% by weight of reduced indigestible dextrin, 0.01 to 0.5% by weight of sucralose and acesulfame potassium, and 5 to 50% by weight of reduced maltose starch syrup, respectively. The sweetener composition according to (8).
(10) A food comprising the sweetener composition according to any one of (1) to (2) and having an action of suppressing an increase in blood sugar level.

  The sweetener composition of the present invention can provide a low-calorie sweetener composition that suppresses an increase in blood glucose level and has an intestinal regulating action.

  The sweetener composition of the present invention is characterized by containing an oligosaccharide, an indigestible dietary fiber and a high-intensity sweetener, or further a sugar alcohol. Needless to say, it can be used for cooking at home instead of powdered sweeteners such as coffee sugar for tabletop and sugar added to cocoa and the like to sweeten the beverage. On the other hand, it is also possible to take the form of a syrup seasoning such as syrup or honey that is appropriately weighed with a measuring spoon during cooking. That is, any form can be used as long as it is in a form that is easy to use in accordance with daily use situations or a form that is easy to use in cooking, but a syrup or powder form is preferred. The present invention is described in detail below.

The oligosaccharide used in the present invention is indigestible, has little increase in blood glucose level, and has an intestinal regulating action. That is, any substance can be used as long as it does not digest in the small intestine and reaches the large intestine, and exhibits an improvement effect on the intestinal flora and an intestinal regulating action. In other words, any oligosaccharide that is selectively consumed by enterobacteria, such as bifidobacteria, which exhibits various health effects, and is not subject to hydrolysis by digestive enzymes such as small intestinal sucrase. Can be used. An example is fructooligosaccharides produced from sucrose as a raw material. Fructo-oligosaccharides are obtained by binding 1 to 3 molecules of fructose to fructose residues of sucrose, and consist of trisaccharide 1-kestose, tetrasaccharide nystose, and saccharide 1-fructosyl nystose. It has been proved from in vitro tests and animal tests that fructooligosaccharides are not hydrolyzed by digestive enzymes such as small intestinal sucrase.
As the oligosaccharide, it is preferable to use an oligosaccharide obtained by removing impurities that cause blood sugar to such an extent that the blood sugar level is not substantially affected. That is, it is necessary not to contain sugar components that are decomposed in the small intestine such as glucose, sucrose, lactose, maltose, or directly absorbed into blood sugar. Oligosaccharides that can be used in the present invention include fructooligosaccharides, isomaltoligosaccharides, lactosucrose, raffinose, melibiose, stachyose, xylo-oligosaccharides, galactooligosaccharides, nigerooligosaccharides, gentio-oligosaccharides, inulo-oligosaccharides, cyclic oligosaccharides, anhydro sugars, etc. Can be mentioned. Of course, fructooligosaccharides that are a single component of fructooligosaccharide and purified to high purity, such as 1-kestose and nystose, are particularly preferred.

  The indigestible dietary fiber used in the present invention, when taken together with the food component, slows the digestion and absorption of the sugar component by increasing the residence time in the stomach and small intestine. It has the effect of preventing an increase in blood sugar. Moreover, since it is not hydrolyzed also in the small intestine, it has an effect | action as a water-soluble dietary fiber and can exhibit an intestinal regulation function. The indigestible dietary fiber that can be used in the present invention preferably does not contain a component that increases blood glucose level. Undesirable components include sugar components that are decomposed in the small intestine such as glucose, sucrose, lactose, maltose, or directly absorbed into blood sugar. Examples of the indigestible dietary fiber that can be used in the present invention include indigestible dextrin, reduced indigestible dextrin, alginic acid, alginic acid partial degradation product, polydextrose, guar gum, and guar gum partial degradation product.

As the high-intensity sweetener that can be used in the present invention, any sweetener having high sweetness can be used, and examples thereof include sucralose, acesulfame potassium, aspartame, stevia, thaumatin, and glycyrrhizin. . By appropriately adjusting the blending amount, a sweetener composition having good quality sweetness similar to that of sucrose can be obtained by utilizing the sweetness of the oligosaccharide.
Any sugar alcohol that can be used in the present invention can be used as long as the sweetness can be adjusted and the calorie content is low. For example, erythritol, xylitol, sorbitol, mannitol, maltitol, isomaltitol, lactitol, palatinit, reduced maltooligosaccharide (reduced maltose starch syrup, etc.) can be used.

Preferred forms for carrying out the present invention include fructooligosaccharides as oligosaccharides, reduced indigestible dextrins as indigestible dietary fibers, sucralose and / or acesulfame potassium as high-intensity sweeteners, and reduced maltose starch syrup as sugar alcohol. A blended syrupy sweetener composition may be mentioned. Further preferred forms are 5 to 90% by weight of fructooligosaccharide, 5 to 90% by weight of reduced resistant digestible dextrin, 0.01 to 0.5% by weight of sucralose and acesulfame potassium, and 5 to 50% of reduced maltose starch syrup, respectively. % Syrupy sweetener composition.
Further, as shown in Example 4 of the present invention, a powdery sweetener composition can be obtained. In this case, not the reduced resistant digestible dextrin but the resistant digestible dextrin may be used. In the case of a syrupy sweetener composition, it is preferable to use a reduced indigestible dextrin because of the risk of browning.

  Food additives can be added to the sweetener composition of the present invention for various purposes. For example, for flavoring purposes, flavoring agents such as l-menthol and citronellal, citric acid, tartaric acid, sodium carbonate, sodium acetate, lactic acid, sodium bicarbonate, sodium carbonate, potassium carbonate and other pH adjusters, benzoic acid, sorbic acid Preservatives such as propionic acid and ethyl paraoxybenzoate, thickeners such as alginic acid, carboxymethylcellulose, methylcellulose, antioxidants such as calcium sodium ethylenediaminetetraacetate, vitamin C, glutathione, cysteine, edible red No. 2, edible Coloring agents such as Yellow No. 4 can be appropriately blended.

Hereinafter, although the content of the present invention is explained concretely using an example, the present invention is not limited to these at all.
Example 1
Fructooligosaccharide (Mayoligo P solution (fructo-oligosaccharide content approximately 71%), Meiji Seika Co., Ltd.), reduced resistant digestive dextrin (Fibersol 2HL (reduced resistant digestible dextrin content approximately 66%), Matsutani Chemical Industry Co., Ltd. ), Reduced maltose syrup (mabit (maltitol content: about 56%), Hayashibara Co., Ltd.), erythritol 50% aqueous solution (erythritol content: 50%, Nikken Chemical Co., Ltd.), sucralose (manufactured by Saneigen FFI) A sweetener composition was prepared from acesulfame potassium (Sanet, manufactured by Neutrino-Vacia) using the composition shown in Table 1, and the sweetness and calorie of the resulting solution were calculated. The sweetness was measured by preparing a 1.0% aqueous solution according to Pauli's whole series method. The measurement results are shown in Table 1 as relative values when the sweetness of sucrose is 100. The calorie showed the calorie | heat amount of 1 meal design amount (13.5g).

(Example 2)
The change in blood glucose level immediately after ingesting 13.5 g of syrup of composition 3 described in Example 1 was compared with the increase in blood glucose when ingesting 9.0 g of sucrose having the same sweetness. The blood glucose level was measured using a self blood sampling method. The blood glucose level was measured according to the manual using a gluco card diameter set (manufactured by ARKRAY). The measurement results are shown in FIG. From this result, when 13.5 g, which is a predetermined amount per meal, was ingested, an increase in blood glucose level due to ingestion was not observed.

(Example 3)
Inari sushi was prepared using the composition 3 described in Example 1. The boiled broth and sushi rice for frying are prepared with the composition shown in Table 2.

After frying, the deep-fried fried food was fully squeezed and prepared. Put the broth in a pan, boil it, add the fried oil, drop the lid, and simmer for 40 minutes until the broth is almost gone. Separately, vinegared rice was prepared according to the formulation shown in the above table, and finally roasted sesame was mixed to make sushi rice. I put 45g of sushi rice into a deep-fried fried rice, shaped it and folded my mouth. The prepared two types of inari sushi took rough heat and cooled.
The change in blood glucose level after oral intake of each of Inari Sushi A (Comparative Example) and Inari Sushi B (Example 3) (270 g each) was measured using a self blood sampling method. The blood glucose level was measured according to the manual using a gluco card diameter set (manufactured by ARKRAY). Changes in blood glucose level after inari sushi A and inari sushi B are shown in FIG. As a result, it was shown that the food of the present invention also suppresses an increase in blood glucose level due to diet-derived carbohydrates.
As a result of the above, it was demonstrated that the peak of blood glucose can be suppressed by about 30 mg / dl by ingesting sushi sushi B (Example 3) prepared using the sweetener composition of the present invention, and the effect of suppressing postprandial hyperglycemia Became clear.

Example 4
1-kestose (Mayoligo CR, manufactured by Meiji Seika Co., Ltd.) 33.3% by weight as oligosaccharide, indigestible dextrin (Fibersol 2, manufactured by Matsutani Chemical) 44.3% as indigestible dietary fiber, and reduced maltose as sugar alcohol Minamata (Crystal Mabit, Hayashibara) 22.2% by weight, sucralose 0.2% by weight as high-intensity sweetener, acesulfame potassium 0.1% by weight, sodium lactate, sodium ascorbate, etc. as other additives A powdery sweetener composition was obtained. The obtained powder was low in hygroscopicity and easy to handle. The sweetness was as good as sucrose.

  The sweetener composition for suppressing an increase in blood glucose level of the present invention can be provided as a sweetener useful for those who need to suppress an increase in blood glucose level and limit caloric intake, such as diabetic and obese patients.

2 shows changes over time in blood glucose level when 9 g of sucrose and 13.5 g of syrup of composition 3 described in Example 1 were orally ingested. The time-dependent change of a blood glucose level after eating Narari Sushi A (comparative example) prepared using sugar and Narari Sushi B (Example 3) prepared using the sweetener composition of this invention is shown.

Claims (10)

A sweetener composition comprising an oligosaccharide, an indigestible dietary fiber, and a high-intensity sweetener, and suppressing an increase in blood sugar level. A sweetener composition characterized by further containing a sugar alcohol in the composition according to claim 1 to suppress an increase in blood sugar level. The sweetener composition as described in any one of Claims 1-2 whose oligosaccharide is fructooligosaccharide. The sweetener composition according to claim 3, wherein the fructooligosaccharide is one or more selected from 1-kestose, nystose or 1-fructosyl nystose. The sweetener composition according to any one of claims 1 to 2, wherein the indigestible dietary fiber is at least one selected from reduced indigestible dextrin or indigestible dextrin. The sweetener composition according to any one of claims 1 to 2, wherein the high-intensity sweetener is one or more selected from sucralose or acesulfame potassium. The sweetener composition according to claim 2, wherein the sugar alcohol is at least one selected from reduced maltose starch syrup or erythritol. The sweetener composition according to claim 2, wherein the oligosaccharide is fructo-oligosaccharide, the indigestible dietary fiber is reduced indigestible dextrin, the high sweetness sweetener is sucralose and / or acesulfame potassium, and the sugar alcohol is reduced maltose starch syrup. . 5 to 90% by weight of fructooligosaccharide, 5 to 90% by weight of reduced indigestible dextrin, 0.01 to 0.5% by weight of sucralose and acesulfame potassium, respectively, and 5 to 50% by weight of reduced maltose starch syrup Item 9. The sweetener composition according to Item 8. The foodstuff which contains the sweetener composition as described in any one of Claims 1-2, and has the effect | action which suppresses the raise of a blood glucose level.

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