JP2005296137A - Syringe with connector, connector for use in syringe, and syringe - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a syringe exhibiting a high operability in both cases of using and non-using a lock nut, the lock nut for use in the syringe and the syringe mountable the lock nut. <P>SOLUTION: The easily attachable/detachable and bottomed cylindrical-body lock nut 30 is mounted to a lure part 120 of the prefilled syringe 1. A female screw 3010 is threadedly cut inside a side face 301 corresponding to the cylindrical part of the lock nut 30 and threadedly engaged with a port 50 of a line system. The main surface part 302 of the lock nut 30 is formed with a gourd-shaped hole bored by communicating a guide hole 3021 with a fixing hole 3022 mutually and, when the lock nut is non-used, the lure part 120 is fixed in the fixing hole 3022. When the lock nut 30 is non-used, the lure part 120 is moved to the side of the guide hole 3021 to separate the both. <P>COPYRIGHT: (C)2006,JPO&NCIPI

Description

  The present invention relates to a syringe with a connection tool, a connection tool used for the syringe, and a syringe.

In a medical field, a syringe that is a so-called syringe barrel is used by various usage methods.
For example, generally, a stapler type connector such as a needle base provided with a needle tube is attached to a luer part at the tip of a syringe, and blood is collected from a patient or used to administer a drug stored in a syringe to a patient.

  A syringe may also be used in a system called a pipeline system such as an infusion line system or a blood collection line system. In this system, a syringe is connected to an external port of the line system, and a medicine in the syringe is administered from there, or conversely, collection is performed from the line. As a method for connecting such a syringe and a line system, a direct connection method in which a luer part is directly inserted into the port of the line system, and a luer part and the port are screwed and connected using a connection tool (lock nut). A fixed connection method is used.

  A prefilled syringe may be used for the syringe in a medical field. In this prefilled syringe, a drug is injected into the syringe body in advance. In this case, the tip of the nozzle of the syringe body is sealed with, for example, resin, but when used, this portion is opened and the plunger is pushed in to discharge the medicine. According to such a prefilled syringe, it is possible to reduce the labor and time required for drug administration and drug mixing to a patient and prompt prompt processing.

By the way, a syringe that can be fixedly connected to the port of the line system is often equipped with a lock nut as a set at the luer part from the beginning. In order to securely connect the syringe and the line system, a stepped portion having a different diameter is provided in the luer part, and a lock nut is inserted in the luer part in advance so that the stepped part is held in place. The connection operation can be performed.
Japanese Patent Laid-Open No. 7-8271

However, as shown in FIG. 10, such a syringe with a connector has a problem in that the lock nut becomes an obstacle to the direct connection type port, and the luer part cannot be connected to the port.
As another problem, as shown in FIG. 11, when trying to attach a needle base to the luer part with respect to the above-mentioned syringe with a connecting tool, the lock nut interferes with the user, The correct positional relationship cannot be grasped, and the lure part and the needle base cannot be connected well. In addition, since the lock nut is set in the luer part, the length of the lure part exposed to the outside is insufficient, and there is a problem that the needle base cannot be sufficiently held in the luer part. .

Thus, the problem in the versatility of the syringe with a lock nut is desired to be improved immediately in response to a request from a medical site that requires a quick and accurate response.
The present invention has been made in view of the above problems, and its purpose is that it can be fixedly connected to a port and has high operability even in the case of direct connection without using a connector. It is providing the syringe which can be exhibited, the connection tool used for this syringe, and the syringe which can mount | wear with the said connection tool.

  In order to solve the above-described problem, the present invention provides a syringe with a connection tool for connecting a syringe to a port, the syringe having a connection tool arranged on a luer part of a syringe body, and the luer part includes a connection tool and An engaging portion for engaging is formed, and the connector has a first hole that engages with the engaging portion of the luer portion along the syringe axial direction, and is larger than the first hole and in the syringe axial direction. A second hole through which the luer part can be freely inserted and removed is formed so as to communicate with each other.

In addition, the present invention may specifically be configured such that the first hole and the second hole communicate with each other via a passage.
Further, in the present invention, the engaging portion may be configured as a stepped portion existing between the tip and the root of the luer portion.

  In such a configuration of the present invention, specifically, first, the luer part is inserted into the second hole (free insertion hole) of the connector, and then the luer part is slid into the first hole (engagement hole). Thus, the root side of the engaging portion of the luer portion can be fitted into the engaging hole of the connecting portion, whereby the connecting tool can be engaged and attached to the syringe. The user can thus attach the connector to the syringe side and connect the syringe to a fixed connection port such as an infusion line system using the connector.

Secondly, in the present invention, the connection tool can be easily removed from the luer part by relatively moving the luer part engaged by the engagement hole of the connection tool to the loose insertion hole side.
If the connection tool is removed from the luer part in this way, the connection tool does not get in the way when the lure part is directly connected to the connection type port, so the lure part can be directly connected to an infusion line system or the like that does not use the connection tool. It can be reliably connected to a connection type port, and high versatility can be exhibited.

  In addition, with the prefilled syringe of the conventional configuration, it is difficult for the user to check the position of the luer part and the needle base due to the connection tool being interrupted, and the needle base is firmly attached to the back of the luer part because of the connection tool. However, in the present invention, since the connector can be easily separated from the syringe as described above, such a conventional problem can be fundamentally solved.

  Further, in the present invention, the first hole and the second hole are provided so that the first hole and the second hole communicate with each other via the passage, so that the luer part pushes the passage between the passages in a forced fit state during use. It can be moved to the engagement hole and securely fitted.

1. Embodiment 1
1-1. Overall Configuration of Prefilled Syringe FIG. 1 is a cross-sectional view showing a configuration of a prefilled syringe and a connection tool (lock nut) according to Embodiment 1 of the present invention. In addition, although it was set as the structure which combined a prefilled syringe and a lock nut here, you may apply this invention to syringes other than a prefilled syringe. Here, for the sake of explanation, the plunger 40 is not a cross-sectional shape but shows a normal side structure.

The configuration of the prefilled syringe 1 shown in the figure is roughly composed of a syringe body 10, a needle base 20, a plunger (also referred to as a pusher or a piston) 40, and the like.
The syringe body 10 is a cylindrical body formed by injection molding a material having excellent chemical resistance such as polyethylene, polypropylene, polycarbonate, and polyvinyl chloride. The front end side is sealed with a top surface portion 110, and a luer portion 120 projects from the center of the top surface portion 110.

On the other hand, an opening 12 is formed on the rear end side of the syringe body 10. The luer part 120 is basically drawn into a tapered taper shape, but a step part 123 is provided in the middle of the taper shape, so that the luer root part 121 with a small diameter and the lure part 120 tip side A luer tip portion 122 having a large diameter located at is formed.
A lock nut 30, which will be described later, is fitted to the stepped portion 123. The luer tip 122 is tapered according to ISO 6/100, and a general needle base 20 is easily attached. In FIG. 1, a cap 20 is attached to the tip of the luer part 120.

Hereinafter, a direction along the longitudinal direction of the syringe body 10 is referred to as an “axial direction”, and a direction perpendicular to the axial direction is referred to as a “radial direction”.
The plunger 40 is made of a resin material having excellent chemical resistance like the syringe body 10, and has a disk-shaped end portion having a main surface in the radial direction at both ends of the plunger body 42 having a cross-sectional shape for reinforcement purposes. With structure. One of the end portions is a pressing end portion 41 for a user to press with a finger, and the other end portion is a head portion 43 that is inserted into the syringe body 10 in the axial direction.

A packing 44 is disposed at the tip of the head portion 43, and the packing 44 comes into close contact with the inner wall of the syringe body 10. Here, the medicine 100 is stored in the syringe body 10 that is internally sealed by the packing 44 and the cap 20.
In the prefilled syringe having such a configuration, the user removes the cap 20 at the time of use so that the medicine 100 can be discharged. Then, when the user pushes the pressing end portion of the plunger 40 toward the syringe side with a finger, the medicine 100 is discharged from the tip of the luer portion 120 according to the pushing amount.

1-2. Configuration of the lock nut The prefilled syringe 1 according to the first embodiment has a lock nut 30 that is a connector that can be easily attached to and detached from the luer part 120 as a feature of the lock nut 30 along the axial direction. It is mounted so as to be engaged with 120 step portions 123. The lock nut 30 is used as a connection tool for connecting the prefilled syringe 10 to a fixed connection type port in an infusion line system or a blood collection line system in a medical field.

The lock nut 30 is a bottomed cylindrical body formed by injection molding a resin material having excellent mechanical strength, and the inner surface of the side surface portion 301 corresponding to the cylindrical portion is, for example, a female screw 3010 of a standard conforming to ISO594-2 Is threaded. The female screw 3010 is screwed with a male screw 5010 described later.
A main surface portion 302 that is in contact with the bottom of the lock nut 30 is formed with a Dharma hole 3020 that is formed such that the two holes communicate with each other (see FIG. 2 for details). One of the two holes is a loose insertion hole 3021, which is formed at a position shifted from the center of the main surface portion 302. The other of the two holes is an engagement hole 3022 that is drilled at the center position of the main surface portion 302. The loose insertion hole 3021 has a diameter that is at least larger than the luer tip 122 so that the entire luer part 120 of the prefilled syringe 1 can be loosely inserted, but the engagement hole 2022 is engaged with the step 123 of the luer part 120. The lock nut 30 is formed slightly smaller than the diameter of the luer tip 122 so that the lock nut 30 can rotate relative to the luer 120. A passage 303 is formed between the loose insertion hole 3021 and the engagement hole 3022, and a portion having a smaller diameter than the diameter of the engagement hole 3022 is formed. The width of the passage 303 is set to be slightly smaller than the diameter of the luer root portion 121 so that the luer portion 120 can move toward the passage 303 only when a certain force or more is applied to the lure root portion 121. Yes.

1-3. Engagement between Syringe and Lock Nut FIG. 2 is a diagram showing a lock nut mounting method and a state after mounting. Among these, FIG. 2 (a) is a view showing a mounting method, and FIG. 2 (b) is a view showing a state after mounting.
According to the lock nut 30 having the above configuration, as shown in FIG. 2 (a), the user first places the luer part 120 of the prefilled syringe 1 in the loose insertion hole 3021 along the axial direction as shown in FIG. Insert it (Figure 2 (a) shows the state of insertion along the A direction (axial direction)). At this time, since the loose insertion hole 3021 has a sufficiently large diameter with respect to the luer tip portion 122 of the luer portion 120, the luer portion 120 can be smoothly inserted into the lock nut 30.

  Then, as a second step, after the user firmly inserts the luer part 120 into the lure root part 121 into the loose insertion hole 3021, the side surface of the luer root part 121 contacts the wall surface of the loose insertion hole 3021 through the passage 303. Then, the lure part 120 is moved to the engagement hole 3022 (FIG. 2 (a) shows a state of moving toward the B direction). At this time, the luer root portion 121 moves while pushing the gap of the passage 303 in a forced fit state, and the step portion 123 moves to fit into the engagement hole 3022 having a small diameter and is engaged. The diameter of the engagement hole 3022 is adjusted to the diameter of the stepped portion 123, and a passage 303 exists between the engagement hole 3022 and the loose insertion hole 3021. Therefore, as shown in FIG. The step part 123 of the luer part 120 comes into contact with the periphery of the engagement hole 3022 and is securely engaged in the axial direction.

  On the other hand, in the lock nut 30 provided with the Dharma hole 3020, both can be detached as follows after once engaging with the syringe body 10. That is, the user can easily separate the prefilled syringe 1 and the lock nut 30 by moving the luer part 120 from the engagement hole 3021 to the loose insertion hole 3022 side while applying some force to the luer part 120. Is possible. Since this operation can be performed reversibly and easily (for example, with one hand), this makes it easy to attach this to the prefilled syringe 1 only when the locknut 30 is necessary, and remove the locknut 30 when it is unnecessary and remove the prefilled syringe. 1 can be used.

  Here, FIG. 3 is a cross-sectional view showing a state in which the prefilled syringe 1 is connected to the fixed connection type port 50 side of the infusion line system using the lock nut 30. FIG. The female screw 3010 of the lock nut 30 is screwed with the male screw 5010 on the port 50 side, whereby the luer tip 122 of the luer part 120 of the prefilled syringe 1 comes into close contact with the packing 52 provided inside the port 50, It is inserted into the infusion line while pressing this. At this time, in the lock nut 30, the peripheral portion of the engagement hole 3022 is firmly engaged with the stepped portion 123 of the luer part 120 pressed, and even if a slight tensile force is applied to the prefilled syringe 1, The prefilled syringe 1 does not deviate from the port 50 along the axial direction. Accordingly, the user can safely press the plunger 40 into the syringe body 10 and administer the required amount of the drug 100 into the port 50.

  On the other hand, FIG. 4 is a cross-sectional view showing a state in which the lock nut 30 is removed from the prefilled syringe 1 and the prefilled syringe 1 is connected to the direct connection type port 500 side of the infusion line system. As described above, in the first embodiment, since the lock nut 30 is removed, the luer tip 122 of the prefilled syringe 1 is not obstructed by the lock nut 30, and the packing 52 inside the port 500 is correctly and tightly sealed. The connection between the prefilled syringe 1 and the port 500 is realized.

  FIG. 5 is a cross-sectional view showing a state in which the lock nut 30 is removed from the prefilled syringe 1 and the needle base 60 is attached to the luer tip 122. The needle base 60 has a configuration in which a socket portion 61 made of a resin member formed in accordance with the shape of the luer tip portion 122 holds a needle tube 62 as a so-called injection needle. As shown in FIG. 11, with a prefilled syringe having a conventional configuration that cannot be removed while the lock nut is set, it is difficult for the user to check the position of the luer part and the needle base due to the lock nut being disturbed. There was a risk that the user could touch the infecting bacteria by puncture. In addition, since there is a lock nut, there is a problem that it is difficult to firmly attach the needle base to the depth of the luer part.In the first embodiment, the lock nut 30 can be easily detached from the prefilled syringe 1 by the Dharma hole 3020. Such a conventional problem can be fundamentally solved.

<About other embodiments>
The dharma hole of the first embodiment has a pattern shape in which the circular loose insertion hole and the engagement hole communicate with each other through the passage, but the present invention can be applied to other embodiments described below. .
2. Embodiment 2
In the dharma hole 3020a in the lock nut 30A of the second embodiment shown in FIG. 6, the loose insertion hole 3021a and the engagement hole 3022a overlap each other, and the overlapping portion of the periphery of each hole forms a passage 323a.

In the present invention, even with the Dalma hole 3020a having such a pattern shape, the same effects as those of the first embodiment are exhibited. In addition to this, the passage 303a of the second embodiment is a portion where the loose insertion hole 3021a and the engagement hole 3022a overlap each other, which is slightly sharper than the first embodiment. The engagement holes 3022a can be engaged.
3. Embodiment 3
The Dalma hole 3020b in the lock nut 30B of the third embodiment shown in FIG. 7 has an engagement hole 3022b formed between two loose insertion holes 3021bA and 3021bB. The loose insertion holes 3021bA, 3021bB, and the engagement holes 3022b have shapes in which the circles of the holes overlap each other, but the holes may communicate with each other through a passage. The sizes and shapes of the loose insertion holes 3021bA and 3021bB do not have to be the same as each other, but at least the stepped portion 123 of the luer portion 120 needs to be sized to be loosely inserted.

  According to the Dharma hole 3020b having such a configuration, the luer part 120 can be moved from the engagement hole 3022b to either of the two loose insertion holes 3021bA and 3021bB in use, so that the lock nut 30 can be easily attached and detached. And the burden on the user's operation can be reduced. In particular, in a medical field where the user is required to operate the prefilled syringe 1 and the lock nut 30 with one hand based on a treatment method using the prefilled syringe 1, the third embodiment is extremely convenient. The effect that can be demonstrated.

4. Embodiment 4
In the Dalma hole 3020c in the lock nut 30C of the fourth embodiment shown in FIG. 8, the circular engagement hole 3022c has a pattern shape communicating with the rectangular loose insertion hole 3021c via the passage 3023c.
Even with such a configuration, the same effect as the lock nut 30 of the first embodiment can be obtained. Further, since the shapes of the loose insertion holes 3021c and the engagement holes 3022c are clearly different, there is an advantage that the user can easily recognize and distinguish these holes without making a mistake and use the lock nut 30c correctly.

5. Embodiment 5
In the dharma hole 3020d in the lock nut 30D of the fifth embodiment shown in FIG. 9, the circular engagement hole 3022c has a pattern shape communicating with the hexagonal (honeycomb shape) loose insertion hole 3021d through the passage 3023c. ing.
Even with such a configuration, the same effect as the lock nut 30 of the first embodiment can be obtained. As in the fourth embodiment, since the shapes of the loose insertion holes 3021d and the engagement holes 3022d are clearly different, the user can easily recognize and distinguish these holes without making a mistake, and can use the lock nut 30d correctly. An effect is also produced.

6. Other matters In the prefilled syringe 1 of the present invention, the example in which the lock base 30 is removed and then the needle base 60 is attached has been described. However, the invention is not limited to this, and the pipe base lure is not limited to this. Or a tube may be used. In the prefilled syringe 1 equipped with a needle base, it is effective to attach a cap or the like so as to cover and protect the needle base and the needle tube from above in order to prevent erroneous puncture. As this cap, the same cap as that used for the vial can be used.

In each of the above embodiments, a configuration example of a connection tool (lock nut) in which a female thread is threaded is disclosed, but the present invention is not limited to this configuration, and an intermittent threading structure, a cup joint structure, etc. You may make it connect with the port side of a line system suitably with another structure.
Further, the luer part of the syringe used in the present invention is not limited to a circular cross-sectional shape, and for example, one or both of the luer tip part and the luer root part have a rectangular cross-sectional shape, an elliptical cross-sectional shape, and a triangular cross-sectional shape. There may be. However, it is desirable to appropriately set the shape of the engagement hole according to the cross-sectional shape of the step portion of the luer part so that the luer part can be reliably engaged with the engagement hole of the lock nut.

  The syringe with a connector of the present invention, the connector used for the syringe, and the syringe can be used for the purpose of administering a drug solution to a patient or collecting blood at a medical site.

3 is a cross-sectional view showing a configuration of a prefilled syringe according to Embodiment 1. FIG. It is a figure which shows the mounting method of a lock nut. It is a figure which shows the connection state to the fixed connection type port of a prefilled syringe. It is a figure which shows the connection state to the direct connection type port of a prefilled syringe. It is a figure which shows the structure of the prefilled syringe equipped with the conventional needle base. FIG. 6 is a diagram showing a configuration of a lock nut in a second embodiment. 6 is a diagram showing a configuration of a lock nut in a third embodiment. FIG. FIG. 6 is a diagram showing a configuration of a lock nut in a fourth embodiment. FIG. 10 is a diagram showing a configuration of a lock nut in a fifth embodiment. It is a figure which shows the structure of the conventional lock nut and a prefilled syringe. It is a figure which shows the structure of the conventional lock nut and a prefilled syringe.

Explanation of symbols

1 Prefilled syringe
10 Syringe body
12 (Rear end side) Opening
20 cap
30, 30A-30D Lock nut
40 Plunger
41 Pressing end
42 Plunger body
43 Head
44, 52 Packing
50, 500 ports
100 drugs
110 Top surface
120 lure
121 Luer tip
122 Luer root
123 Step
301 Side
303, 303a-303d passage
3010 Female thread
3020, 3020a-3020d Dharma hole
3021, 3021a-3021d loose insertion hole
3022, 3022a to 3022d engagement hole

Claims (7)

The connector for connecting the syringe to the port is a syringe with a connector arranged on the luer part of the syringe body,
The luer part is formed with an engaging part for engaging with the connection tool,
The connecting tool has a first hole that engages with the engaging portion of the luer portion along the syringe axial direction,
A syringe with a connector, wherein the second hole, which is larger than the first hole and through which the luer part can be inserted and removed along the syringe axial direction, is formed so as to communicate with each other. 2. The syringe with connection tool according to claim 1, wherein the first hole and the second hole communicate with each other through a passage. 3. The syringe with connection tool according to claim 1 or 2, wherein the engaging portion is a step portion existing between a tip and a root of the luer portion. A connector for attaching the syringe to the port, which is attached to the luer part of the syringe body,
A first hole engaged with the luer portion along the syringe axial direction;
A connection tool characterized in that a second hole larger than the first hole and in which the luer part can be inserted and removed along the syringe axial direction is formed in a state of communicating with each other. 5. The connection tool according to claim 4, wherein the first hole and the second hole communicate with each other through a passage. In the lure part of the syringe body, it is provided with an engaging part consisting of a step part formed between the tip and the root of the lure part,
The engaging portion engages with the first hole of the connecting tool according to claim 4 or 5, so that the connecting tool is engaged with the luer portion, and the luer portion is connected to the second hole of the connecting tool. A syringe characterized in that the luer part is detached from the connector side by being moved. A therapeutic method comprising administering a drug to a patient using the syringe with a connector according to any one of claims 1 to 3.

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