JP2005237863A - Catheter and manufacturing method thereof - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a catheter having a large cross-sectional area of a main lumen such as a suction lumen while having a rapid exchange type structure.
A catheter having a first lumen having an opening at a distal end and a proximal end, and a second lumen having an opening at a distal end and a proximal end, the distal end side of the first lumen The opening is formed with an inclination in a direction approaching the second lumen side from the proximal end toward the distal end, and is more proximal to the second lumen than the proximal end at the distal end opening of the first lumen An end opening is arranged in the distal end direction.
[Selection] Figure 2

Description

  The present invention relates to a catheter that can be suitably used as a suction catheter or the like used for sucking and removing a thrombus or the like in a blood vessel, and a method for manufacturing the same.

  For myocardial infarction in which the coronary artery is occluded by a thrombus and the blood flow in the coronary artery is obstructed, a treatment method in which the occlusion site is expanded by a balloon catheter is mainly used.

  However, when the occlusion site is expanded by the balloon catheter, the thrombus may be detached from the occlusion site and flow out, and the peripheral blood vessel may clog the thrombus. Therefore, when a balloon catheter is used in a case where the coronary artery is occluded by a large amount of thrombus, severe peripheral embolism may be induced.

  In recent years, it has become clear that a treatment method (coronary thrombus aspiration therapy) that sucks and removes a thrombus using an aspiration catheter as described in Patent Document 1 is effective for such cases. It has become to.

  The aspiration catheter described in Patent Document 1 has a lumen (guide wire lumen) 46 for inserting the guide wire 14 as shown in FIG. 4 for insertion along the guide wire inserted into the blood vessel. doing. This suction catheter employs a structure (rapid exchange structure) having a guide wire lumen 46 over the distal end and middle abdomen of the catheter.

In this rapid exchange type suction catheter, unlike a catheter having a guide wire lumen over its distal end and proximal end (over-the-wire structure), the guide wire and the catheter are arranged outside the body (proximal end side). Since they are separated, it is possible to pull back only the catheter without moving the guide wire. Therefore, after the thrombus has been aspirated with this suction catheter, only the catheter can be extracted from the blood vessel while leaving the guide wire in the blood vessel. This catheter can be inserted along with this, and the subsequent treatment can be performed quickly. Due to this advantage, a rapid exchange type structure is used as the suction catheter.
US Pat. No. 5,827,229

  However, in the suction catheter of Patent Document 1, the guide wire lumen 46 and the lumen 18 for sucking the thrombus (suction lumen) 18 exist in parallel at the distal end portion of the catheter. There has been a problem that the cross-sectional area becomes small. Therefore, the suction lumen at the distal end portion of the catheter where the guide wire lumen is present becomes a bottleneck, and the suction performance of the suction lumen 18 is reduced, so that it is difficult to sufficiently suck the thrombus. There was a problem.

  In view of this problem, an object of the present invention is to provide a catheter having a large cross-sectional area of a main lumen such as a suction lumen while having a rapid exchange structure.

In order to solve the above-mentioned problems, the present inventors have made extensive studies on the positional relationship of lumens in a rapid exchange type catheter, and as a result, can increase the cross-sectional area of a main lumen such as a suction lumen. As a result, the present invention has been completed.
Thus, according to a first aspect of the present invention, a catheter having a first lumen having openings at the distal and proximal ends and a second lumen having openings at the distal and proximal ends. The distal end opening of the first lumen is formed with an inclination in a direction approaching the second lumen side from the proximal end toward the distal end, and the distal end opening of the first lumen is recently A catheter is provided in which the proximal end side opening of the second lumen is arranged in the distal end direction rather than the distal end portion.

  The second lumen is preferably a guide wire lumen.

  The first lumen is preferably a suction lumen.

  And according to the 2nd viewpoint of this invention, it has the 1st lumen which has an opening in a distal end and a proximal end, and the 2nd lumen which has an opening in a distal end and a proximal end, The opening on the distal end side of the lumen is formed with an inclination in the direction approaching the second lumen side from the proximal end toward the distal end, and from the most proximal end in the distal end opening of the first lumen Is a method of manufacturing a catheter in which the proximal end opening of the second lumen is disposed in the distal end direction, and extends between the distal end and the proximal end of the tip member and is disposed parallel to each other. Providing a lumen A and a lumen B, a integrally formed tip member, and a body member comprising a lumen C extending between a distal end and a proximal end of the body member, the distal end of the lumen A Is inclined toward the lumen B side from the proximal end toward the distal end Resecting the distal end of the tip member to have an opening with the proximal end of lumen B being more distal than the proximal end of the opening with the slope of the distal end of lumen A Cutting the proximal end of the tip member so as to have a directional opening, and connecting the distal end of the tip member and the distal end of the body member so that the lumen A and the lumen C are in communication with each other. A method of manufacturing a catheter having a connecting step.

  The catheter manufacturing method of the present invention preferably further includes a step of deforming the distal end member so that the axis of the lumen A and the axis of the lumen B are brought close to each other.

  According to the present invention, in the catheter having the first lumen and the second lumen, the proximal end side opening of the second lumen is arranged in the distal end direction rather than the most proximal end portion in the distal end side opening of the first lumen. Thus, by preventing the first lumen and the second lumen from overlapping in the direction perpendicular to the longitudinal direction of the catheter, the cross-sectional area of the first lumen can be kept large even at the distal end portion of the catheter. As a result, the catheter having excellent suction performance and the like is provided while having a rapid exchange structure without limiting the cross-sectional area of the first lumen due to the presence of the second lumen at the distal end portion of the catheter.

  In addition, according to the catheter manufacturing method of the present invention, the catheter of the present invention having the above-described structure can be easily manufactured, and the catheter of the present invention is strong and does not separate in the blood vessel. Can be manufactured.

Hereinafter, the case where the first lumen of the catheter of the present invention is used as a suction lumen and the second lumen is used as a guide wire lumen, that is, the case where the present invention is applied to a suction catheter having a rapid exchange type structure will be described as an example. . In addition, in order to facilitate understanding of the present invention, reference numerals in the accompanying drawings are added in parentheses, but the present invention is not limited to the illustrated form.
FIG. 1 is a side view of an aspiration catheter 100 as an example of the present invention. The suction catheter 100 is configured by connecting a catheter tube 60 to a connector 80 at a proximal end thereof and fitting a strain relief 70 to the connection portion. When the catheter 100 is used, the connector 80 is connected to a negative pressure source such as a syringe or a suction pump.

  The catheter tube 60 is constituted by the distal end portion 10 and the main body portion 15. The distal end portion 10 has a guide wire lumen 20 and a suction lumen 30 (see FIG. 2), which will be described later, and the main body portion 15 has only the suction lumen 30. The total length of the catheter tube 60 is determined by the distance from the insertion position into the body to the occlusion position such as a thrombus, and is usually 500 to 2000 mm. The outer diameter of the catheter tube 60 is determined by the inner diameter of the blood vessel into which the catheter 100 is inserted, and is usually 0.51 to 4.0 mm.

  When a negative pressure generating source is connected to the connector 80, a suction force is generated in the distal end side opening 34 (see FIG. 2) of the suction lumen 30 in the distal end portion 10 through the suction lumen 30 of the catheter tube 60, and from here Thrombus can be aspirated. The aspirated thrombus is held in the aspiration lumen 30 or is captured by a negative pressure source syringe, a suction pump trap, or the like.

  The catheter tube 60 is preferably formed of a flexible organic polymer material. Specific examples thereof include polyethylene, polyethylene terephthalate, polypropylene, ethylene-propylene copolymer, and ethylene-vinyl acetate copolymer. Examples of the polymer include polyvinyl chloride, cross-linked ethylene-vinyl acetate copolymer, polyether ether ketone, polyurethane, polyamide, polyamide elastomer, polyimide, silicone rubber, natural rubber, and fluorine resin such as polytetrafluoroethylene. Among these, it is particularly preferable to use any one of fluorine resins such as polyurethane, polyethylene, polyamide, polyamide elastomer, and polytetrafluoroethylene.

  The catheter tube 60 may be a laminated tube by laminating two or more kinds of polymer materials. Further, the catheter tube 60 may be configured by changing the material used in the longitudinal direction of the catheter 100. In this case, it is preferable to change the material so that the catheter tube 60 becomes flexible from the proximal end toward the distal end because the insertion property of the catheter 100 into the blood vessel is improved.

  Furthermore, it is preferable to embed a reinforcing member such as a metal mesh or metal wire in the catheter tube 60. By embedding the reinforcing member, the thickness of the catheter tube 60 can be reduced while maintaining the strength necessary for the catheter tube 60. Accordingly, the suction area of the suction catheter 100 can be improved by increasing the sectional area of the suction lumen 30 without increasing the outer diameter of the catheter tube 60. The reinforcing member is preferably provided only around the suction lumen 30 in the main body portion 15 and is not provided in the distal end portion 10. If the reinforcing member is provided at the distal end portion 10, the distal end portion 10 becomes too rigid, and it may be difficult to insert the catheter 100 into the coronary artery, or the blood vessel may be damaged during the insertion. It is.

  An example of the structure of the catheter tube 60 is a catheter tube 60 in which the tip portion 10 is made of polyamide elastomer and the main body portion 15 has a three-layer structure. In this three-layer structure, the inner layer is formed of polytetrafluoroethylene, the intermediate layer is formed of a mesh member such as stainless steel as a reinforcing member, and the outer layer is distal from the proximal end side in the longitudinal direction of the catheter 100. A three-layer structure formed by changing materials in the order of polyamide, relatively rigid polyamide elastomer, and relatively soft polyamide elastomer toward the ends.

  In addition, it is preferable to coat the outer peripheral surface of the catheter tube 60 with a hydrophilic polymer material having lubricity from the viewpoint of reducing friction when the catheter 100 is inserted into the blood vessel. The hydrophilic polymer substance includes a natural polymer type and a synthetic polymer type. Examples of the natural polymer type include starch type, cellulose type, tannin / lignin type, polysaccharide type, and protein type. Synthetic polymers include PVA, polyethylene oxide, acrylic acid, maleic anhydride, phthalic acid, water-soluble polyester, ketone aldehyde resin, (meth) acrylamide, polyamine, water-soluble nylon Etc. are exemplified.

  Among these, cellulose-based polymer materials (for example, hydroxypropylcellulose), polyethylene oxide-based polymer materials (for example, polyethylene glycol), maleic anhydride-based polymer materials (for example, methyl vinyl ether maleic anhydride copolymer) A maleic acid copolymer) and an acrylamide polymer material (for example, polydimethylacrylamide) are particularly preferable as the above-mentioned hydrophilic polymer material because a film having a low friction coefficient can be stably obtained.

  The connector 80 is a cylindrical body provided with a port therein, and its proximal end has a structure that can be connected to a negative pressure generating source such as a suction pump equipped with a syringe or a trap. The distal end of the connector 80 is connected to the catheter tube 60. By connecting a negative pressure generation source to the connector 80 and setting the port 80 of the connector 80 and the suction lumen 30 of the catheter tube 60 to a negative pressure, a suction force is generated in the distal end side opening 34 of the suction lumen 30. A thrombus or the like can be sucked from the distal end side opening 34. The material of the connector 80 is not particularly limited. For example, it is preferable to use a thermoplastic resin such as a polypropylene resin, an ABS resin, a polycarbonate resin, a polyamide resin, or a polyacrylate resin.

  A strain relief 70 shown in FIG. 1 is a cylindrical body that is externally fitted at a connection portion between the catheter tube 60 and the connector 80, and is applied to the catheter tube 60 from a direction perpendicular to the longitudinal direction of the catheter 100. It has a role to absorb power. Since there is a large difference in rigidity between the low-rigidity catheter tube 60 and the high-rigidity connector 80, stress is easily concentrated on the catheter tube 60 at the connection point between the catheter tube 60 and the connector 80, and the catheter tube 60 is bent and damaged. Phenomenon (kink phenomenon) may occur. The strain relief 70 solves this problem. The strain relief 70 is externally fitted to a connection portion between the catheter tube 60 and the connector 80, so that the catheter tube 60 and the connector 80 are connected to each other from the direction perpendicular to the longitudinal direction of the catheter 100. It is possible to disperse the force applied to the vicinity of the connection location of the kink and prevent the kink phenomenon. The material of the strain relief 70 is preferably a material having rigidity about the middle between the catheter tube 60 and the connector 80, such as polyolefin elastomer, and rich in elasticity.

  The contrast marker 40 shown in FIG. 1 can detect the position by X-ray fluoroscopy, and serves as a marker in the body. For example, the contrast marker 40 is formed of a metal material such as gold, platinum, or tungsten. The shape of the contrast marker 40 is not particularly limited, but is preferably a ring shape. In the illustrated aspiration catheter 100, a ring-shaped contrast marker 40 is used. The position where the contrast marker 40 is provided may be near the distal end of the guide wire lumen as shown, or may be near the distal end of the suction lumen. Thereby, by detecting the position of the contrast marker 40 by X-ray fluoroscopy, the position of the distal end portion 10 of the catheter tube 60 can be accurately grasped, and the catheter 100 can be accurately guided to a thrombus or the like. Further, the contrast marker 40 may be attached to the inner peripheral surface or the outer peripheral surface of the catheter tube 60, or may be embedded in the catheter tube 60. When the contrast marker 40 is attached to the inner peripheral surface or the outer peripheral surface of the catheter tube 60, the suction performance of the catheter 100 is made such that the surface of the contrast marker 40 and the inner peripheral surface or the outer peripheral surface of the catheter tube 60 become smooth. It is preferable that the sliding performance of the guide wire 90 and the insertion performance into the blood vessel are not hindered.

  FIG. 2 is an enlarged side sectional view of the distal end portion 10 of the catheter tube 60. The distal end portion 10 of the catheter tube 60 includes a portion of the suction lumen 30 that extends from the distal end opening 34 at the distal end portion 10 to the proximal end opening (not shown) at the proximal end of the catheter tube 60. In the tip portion 10, a guide wire lumen 20 having a distal end side opening 22 and a proximal end side opening 24 is provided. In the distal end portion 10, the distal end side opening 34 of the suction lumen 30 is formed with an inclination in a direction approaching the guide wire lumen 20 side from the proximal end toward the distal end. The inclination angle (inclination angle θ shown in FIG. 2) is 1 to 89 °, and preferably 60 to 80 °. The proximal end side opening 24 of the guide wire lumen 20 is arranged in the distal end direction with respect to the proximal end 31 of the distal end side opening 34 of the suction lumen 30. That is, the proximal end opening 24 of the guidewire lumen 20 passes through the proximal end 31 of the distal end opening 34 of the suction lumen 30 and is perpendicular to the longitudinal direction (Y1) of the catheter (Y direction). The openings 24, 34 of both lumens 20, 30 are arranged so that a vertical line (L 2) passing through the proximal end and perpendicular to the Y direction is located in the direction of the distal end. When the guide wire lumen 20 and the suction lumen 30 are arranged in this way, the suction lumen 30 and the guide wire lumen 20 in the direction perpendicular to the Y direction (X direction) except for the opening portions of the respective lumens. , Do not overlap each other.

  The suction lumen 30 is provided over both the distal end portion 10 and the main body portion 15 of the catheter tube 60. The proximal end of the suction lumen 30 in the body portion 15 is connected to the distal end of the connector 80, and the distal end of the suction lumen 30 in the body portion 15 is connected to the proximal end of the suction lumen 30 in the tip portion 10. ing. The distal end of the suction lumen 30 in the distal end portion 10 is a distal end side opening 34 from which a thrombus and the like are sucked. The length of the suction lumen 30 varies depending on the use of the catheter 100 and the distance from the insertion position of the catheter 100 into the body to the occluded portion such as a thrombus, but is usually 499 to 1999 mm. The diameter of the suction lumen 30 is usually 0.5 to 3.0 mm, and the thickness of the peripheral wall of the suction lumen 30 is usually 0.05 to 0.5 mm. By connecting a negative pressure generating source such as a syringe or a suction pump to the connector 80 and making the inside of the suction lumen 30 have a negative pressure, a suction force is generated in the distal end side opening 34, and this distal end side opening 34. Aspirate blood clots etc. The aspirated thrombus or the like is held in the aspiration lumen 30, or moved from the distal end side to the proximal end side by a suction force and discharged from the proximal end side opening, in the syringe or in the trap of the suction pump, etc. Or captured.

  The guide wire lumen 20 is provided only at the distal end portion 10 of the catheter tube 60, and has a distal end side opening 22 for introducing the guide wire 90 and a proximal end side opening 24 for guiding the guide wire 90. Yes. The length of the guide wire lumen 20 is preferably 1 to 50 mm, and more preferably 5 to 20 mm. By setting the length of the guide wire lumen 20 to 1 mm or more, preferably 5 mm or more, the catheter 100 can be easily oriented along the guide wire 90 inserted into the guide wire lumen 20, and the catheter 100 is inserted into the blood vessel. It becomes easy to do. Further, by setting the length of the guide wire lumen 20 to 50 mm or less, preferably 20 mm or less, the peripheral wall of the guide wire lumen 20 is not obstructed, and the distal end side opening 34 of the suction lumen 30 is blocked by a thrombus or the like. It can be made sufficiently close to the part, and a thrombus and the like can be effectively aspirated. In addition, the diameter of the guide wire lumen 20 is preferably slightly larger than the outer diameter of the guide wire 90, and is usually 0.3 to 1.0 mm (in FIG. 2, in order to simplify the drawing, The guide wire 90 is indicated by a line.) The thickness of the peripheral wall of the guide wire lumen 20 is usually 0.05 to 0.5 mm. The guide wire lumen 20 is preferably formed so that the guide wire lumen 20 and a region extending from the suction lumen 30 along the axis of the suction lumen 30 in the distal end direction overlap each other. By forming the guide wire lumen 20 in this way, the step between the peripheral wall of the guide wire lumen 20 and the peripheral wall of the suction lumen 30 is reduced, so that the insertion of the catheter 100 becomes easier. However, it is preferable that the axis of the guide wire lumen 20 and the axis of the suction lumen 30 do not substantially coincide. When the axial center of the guide wire lumen 20 and the axial center of the suction lumen 30 coincide with each other, the peripheral wall of the guide wire lumen 20 may become an obstacle when sucking a thrombus or the like from the suction lumen 30. The shape of the proximal end opening 24 of the guide wire lumen 20 is not particularly limited, but is preferably formed with an angle of 0 ° to 30 ° with respect to the axis of the suction lumen 30. In this way, the proximal end opening 24 of the guide wire lumen 20 is formed at a relatively small angle with respect to the axial center of the suction lumen 30, so that a step between the peripheral wall of the guide wire lumen 20 and the peripheral wall of the suction lumen 30. , The catheter 100 can be inserted more easily. A guide wire 90 is inserted from the distal end opening 22 of the guide wire lumen 20 toward the proximal end opening 24, the catheter 100 is directed along the guide wire 90, and the catheter 100 is moved to the target portion in the blood vessel. It can be inserted up to a certain thrombus.

  In the catheter 100 of the present invention, in the direction perpendicular to the longitudinal direction of the catheter tube 60, the suction lumen 30 and the guide wire lumen 20 do not overlap each other except for the opening portions of the respective lumens. Therefore, the diameter of the suction lumen 30 is not limited by the presence of the guide wire lumen 20, and the opening of the suction lumen 30 can be opened at the distal end portion 10 of the catheter tube 60 to maximize the cross-sectional area of the catheter tube 60. Can be increased to Thereby, in the suction lumen 30, since there is no bottleneck whose diameter is narrow, thrombus and the like can be sucked effectively.

  In using the catheter 100 having the above-described configuration, the guide wire 90 is first inserted into the coronary artery in the patient's blood vessel, and then the proximal end side of the guide wire 90 is the distal end of the guide wire lumen. It is inserted from the side opening 22 toward the proximal end side opening 24. The catheter 100 is inserted into the blood vessel by pushing the catheter 100 into the blood vessel from the distal end portion 10 side along the guide wire 90 until the distal end portion 10 reaches the occluded portion of the coronary artery.

  When the distal end portion 10 reaches the occluded portion of the coronary artery, a negative pressure source such as a syringe or a suction pump equipped with a trap is connected to the connector 80, and a suction force is applied to the distal end side opening 34 of the suction lumen 30. Is generated. With this suction force, a thrombus or the like in the coronary artery is sucked into the suction lumen 30. Blood flow is restored in the coronary arteries from which blood clots have been sucked and removed. Thereafter, when a subsequent treatment with another catheter is required, only the catheter 60 is extracted from the blood vessel, and the guide wire 90 left in the blood vessel is used as it is, and the other catheter is inserted along the guide wire 90, and quickly. Subsequent treatment can be performed.

As described above, the second lumen 20 of the catheter 100 of the present invention is preferably used as a guide wire lumen, and the first lumen 30 is used as a suction lumen for sucking and removing thrombus and the like in the coronary artery. It is preferable to do. That is, the catheter 100 of the present invention is preferably used as a rapid exchange type suction catheter.
The catheter 100 of the present invention can also be used for other applications. For example, by using the first lumen 30 as a chemical injection lumen for injecting a chemical into the body, and using the second lumen 20 as a guide wire lumen, a rapid exchange type chemical injection catheter can be obtained.

  The method for manufacturing the catheter tube 60 of the catheter 100 of the present invention is not particularly limited. For example, the distal end portion 10 and the main body portion 15 may be formed as separate members and connected to each other. Although the tube member having only one lumen 30 and the tube member having only the second lumen 20 may be joined and manufactured, a method of connecting the tip portion 10 and the main body portion 15 is preferable. As a method of manufacturing the catheter tube 60 of the catheter 100 of the present invention by connecting the distal end portion 10 and the main body portion 15, a method of manufacturing the catheter of the present invention, which is a particularly preferable method, will be described below.

  FIG. 3 is an explanatory view showing a manufacturing process of the catheter 100 of the present invention. FIG. 3A is a diagram showing the cutting process of the tip member, FIG. 3B is a diagram showing the process of attaching the contrast marker 40, and FIG. It is the figure which showed the process of deform | transforming a front-end | tip member. In each figure, cross-sectional views taken along lines A-A ', B-B', C-C ', and D-D' are shown.

  In the catheter manufacturing method of the present invention, a distal end member that becomes the distal end portion 10 of the catheter tube 60 and a main body member that becomes the main body portion 15 of the catheter tube 60 are used. The tip member is a member formed integrally with a lumen A and a lumen B that extend between the distal end and the proximal end of the tip member and are arranged in parallel to each other. In the embodiment shown in FIG. 3, the tip member is formed by an outer wall whose section is a ring and an inner wall whose section is a ring inscribed in the ring, and a lumen B is formed in a region within the inner wall. Lumen A is formed in a region inside and outside the inner wall. Such a tip member can be easily produced by an extrusion method. Next, as shown in FIG. 3 (a), the distal end of the lumen A of the tip member has an opening inclined in a direction approaching the lumen B from the proximal end toward the distal end. The distal end of the tip member is cut away (the right side is the distal end and the left side is the proximal end as viewed in FIG. 3), and the proximal end of the lumen B is at the distal end of the lumen A. The proximal end of the tip member is resected so that it has an opening that is located distal to the proximal end of the beveled opening. Then, as shown in FIG. 3B, a contrast marker 40 is mounted near the distal end in the lumen B. Next, as shown in FIG. 3 (c), the mandrel 92 is inserted and heated from the proximal end side of the lumen A and from the distal end side of the lumen B, respectively. The tip member is deformed so that the axial center of the lumen B approaches each other. Thereby, the shape which the guide wire lumen 20 mentioned above about the catheter tube 60 and the area | region extended in the distal end direction along the axial center of the suction lumen 30 from the suction lumen 30 overlap can be comprised. And the catheter tube 60 is formed by joining the tip member which passed through such a process, and the main-body member provided with the lumen | rumen C extended between a distal end and a proximal end. That is, the catheter tube 60 is formed by connecting the proximal end of the tip member and the distal end of the body member by a technique such as heat fusion so that the lumen A of the tip member and the lumen C of the body member communicate with each other. The second lumen 20 is formed. And the catheter 100 of this invention is manufactured by connecting the proximal end of the catheter tube 60 formed in this way to the connector 80, and fitting the strain relief 70 in this connection location.

  According to the method of connecting the distal end member and the main body member, which is the manufacturing method of the present invention, the distal end member is formed integrally, and the distal end portion 10 of the catheter tube 60 where external force tends to work is not joined. A catheter 100 that is less likely to be damaged in the body can be obtained. Further, by deforming the distal end member so that the lumen A and the lumen B approach each other at the distal end member, the outer peripheral surface of the distal end portion 10 of the catheter tube 60 becomes smooth, and the catheter 100 can be easily inserted into the blood vessel. Become.

It is a side view which shows the whole catheter 100 of this invention. 3 is an enlarged side cross-sectional view showing a distal end portion 10 in a catheter tube 60. FIG. It is explanatory drawing which shows the manufacturing process of the catheter 100 of this invention. It is a figure which shows the catheter of patent document 1 which is a prior art.

Explanation of symbols

100 Catheter 10 Tip portion 15 Body portion 20 Second lumen (guide wire lumen)
21 proximal end 22 distal end opening 24 proximal end opening 30 first lumen (suction lumen)
31 Nearest End 34 Distal End 40 Contrast Marker 60 Catheter Tube 70 Strain Relief 80 Connector 90 Guide Wire 92 Mandrel

Claims (5)

A catheter having a first lumen having openings at the distal and proximal ends and a second lumen having openings at the distal and proximal ends,
The distal end side opening of the first lumen is formed with an inclination in a direction approaching the second lumen side from the proximal end toward the distal end, and in the distal end side opening of the first lumen A catheter in which the proximal end side opening of the second lumen is arranged in the distal end direction rather than the proximal end portion. The catheter of claim 1, wherein the second lumen is a guide wire lumen. The catheter according to claim 1, wherein the first lumen is a suction lumen. A first lumen having an opening at a distal end and a proximal end, and a second lumen having an opening at a distal end and a proximal end, wherein the distal end side opening of the first lumen is a proximal end From the proximal end of the second lumen to the distal end of the second lumen rather than the most proximal end of the distal end opening of the first lumen. A method of manufacturing a catheter in which a side opening is arranged in the distal end direction,
A lumen A and a lumen B extending between the distal end and the proximal end of the tip member and arranged parallel to each other, the tip member formed integrally, and between the distal end and the proximal end of the body member A main body member provided with an extending lumen C;
Cutting away the distal end of the tip member such that the distal end of the lumen A has an opening inclined in a direction approaching the lumen B side from the proximal end toward the distal end;
The proximal end of the tip member is excised so that the proximal end of lumen B has an opening located distal to the proximal end of the opening with a bevel at the distal end of lumen A The process of
and,
Connecting the proximal end of the tip member and the distal end of the body member such that lumen A and lumen C communicate with each other;
The manufacturing method of the catheter which has this. Furthermore, the manufacturing method of the catheter of Claim 4 which has the process of changing the said front-end | tip member so that the axial center of the said lumen | bore A and the axial center of the said lumen | bore B may mutually approach.

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