JP2005179314A - Patch preparation for skin testing - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a patch preparation for a skin testing capable of examining the state of the skin simply and accurately at a low cost. <P>SOLUTION: This patch preparation is provided by forming an adhesive layer 16 on the one of the surfaces of a substrate film 12 having transparency and installing a testing film 20 formed by dissolving or dispersing an indicator displaying a prescribed skin state in a polymer resin having moisture permeability and formed as a film state, pasting the testing film 20 on the adhesive layer 16 of the substrate 12 and printing a color sample 14 of a color developed by the reaction of the indicator with a skin secreted substance, on the base film 12. <P>COPYRIGHT: (C)2005,JPO&NCIPI

Description

  The present invention relates to a skin test patch for inspecting skin moisture retention, pH, and other conditions.

  In general, the skin is preferably in a proper moisture retention state, the skin surface is kept weakly acidic, and healthy skin has an ability to neutralize alkali. However, if the moisture of the skin decreases for some reason, the skin dries out and causes skin surface troubles, and if the skin's alkali neutralization ability decreases, it causes skin diseases.

Conventionally, there has been a biological surface moisture transpiration rate measuring instrument disclosed in Patent Document 1 as a means for easily knowing skin moisture. In this measuring instrument, cobalt chloride paper is pasted on the center of a transparent sheet coated with an adhesive on the periphery or the entire surface, and a protective sheet that can be easily peeled off is attached to the cobalt chloride paper. In this method of using the biological surface moisture transpiration rate measuring instrument, the protective sheet is removed, a transparent sheet is applied to the skin, and the color change of the cobalt chloride paper is observed. Cobalt chloride paper is discolored by moisture emanating from the skin surface while in contact with the skin. Since this color change varies depending on the moisture absorption of the cobalt chloride paper, the amount of moisture evaporated from the skin surface can be determined by comparing the color of the cobalt chloride paper affixed to the skin with a color sample.
Japanese Utility Model Publication No. 62-70502 JP-A-6-32733 Japanese Patent No. 3129738

  In the case of the above conventional technique, the state of the skin cannot be easily detected in a state of being attached to the skin, and the state of change cannot be observed. In addition, the cost of the inspection material is high, and it is not suitable for applications in which the skin condition is inspected on a daily basis.

  The present invention has been made in view of the above-mentioned problems of the prior art, and provides a skin test patch that can be inspected accurately and accurately while maintaining the state of the skin surface, and is inexpensive. For the purpose.

  In the present invention, a pressure-sensitive adhesive layer is formed on one surface of a transparent base film, and an indicator that displays a predetermined skin state is dissolved or dispersed in a polymer resin having moisture permeability to form a film. An inspection film is provided, this inspection film is attached to the adhesive layer of the base film, and a color sample of the color that the indicator reacts with skin secretions is provided on the surface of the base film by printing or the like. It is a patch for skin examination.

  In addition, the present invention also includes forming an adhesive layer on one surface of a transparent substrate film, applying an indicator for indicating a predetermined skin state to a test film of a polymer resin having moisture permeability, and performing this test. A skin test patch comprising a film for application to a pressure-sensitive adhesive layer of the base film, and a color sample in which the indicator reacts with a skin secretion by printing on the surface of the base film. .

  In addition, the present invention also includes forming a pressure-sensitive adhesive layer on one surface of a transparent substrate film, impregnating a moisture-permeable polymer resin test film with an indicator that displays a predetermined skin condition, A skin test patch comprising a film for application to a pressure-sensitive adhesive layer of the base film, and a color sample in which the indicator reacts with a skin secretion by printing on the surface of the base film. .

  The indicator is cobalt chloride or a pH indicator.

  The skin test patch of the present invention can easily and accurately inspect the skin condition of a subject, and can also accurately grasp the change over time of the test. In addition, the manufacturing is easy and the cost can be reduced.

  Hereinafter, embodiments of the present invention will be described with reference to the drawings. 1 to 3 show an embodiment of the present invention. A skin test patch 10 of this embodiment is provided with a transparent base film 12 serving as an adhesive film, and the material thereof is flexible. It is made of a polymer resin film having excellent transparency and toughness. For example, polyvinyl alcohol, polyolefin, polypropylene, polyester, polyvinyl chloride, polyvinylidene chloride, polyethylene, nylon, polyurethane and the like are used. The thickness is, for example, 20 to 100 μm, and preferably 30 to 70 μm.

  On the surface 12 a of the base film 12, a color sample 14 of a predetermined color is provided on the side of an inspection film 20 or the like to be described later, by directly printing or pasting a printed material. The color swatch 14 makes it possible to discriminate the degree of reaction of an indicator, which will be described later, by distinguishing it from appropriate several colors, for example, six colors.

Further, the side of the color swatch 14 is preferably displayed with the value of pH and the amount of water evaporation that the color means. As the displayed value, in the case of pH, for example, a range of 0.2 to 5.2 to 6.4 is entered. Further, in the case of the amount of water evaporation, for example, it is preferable to display a predetermined level in increments of 0 to 0.2 mg / cm ² / h (time).

  A transparent pressure-sensitive adhesive layer 16 for forming a pressure-sensitive adhesive film is provided on the back surface 12 b of the base film 12. The material of the adhesive layer 16 is made of an acrylic adhesive or a synthetic rubber adhesive such as SIS.

  Near the center of the pressure-sensitive adhesive layer 16, a test film 20 formed in a moisture-permeable film shape in which an indicator that displays a predetermined skin state such as pH and water content is dissolved or dispersed is attached. . The test film 20 may be obtained by impregnating a moisture-permeable polymer resin film with an indicator that displays a predetermined skin state such as pH and moisture content.

  Further, as shown in FIG. 3, an indicator 24 that displays a predetermined skin state may be applied to one surface of a test film 22 made of a polymer resin that has moisture permeability and transparency. At this time, when it is better that the indicator 24 does not directly touch the skin, the application surface of the indicator 24 is stuck on the adhesive layer 14.

  The indicator provided on the inspection film 20 may be a pH indicator such as BCP (bromcresol purple), MR (methyl red), CRP (chlorphenol red), PP (phenol purple), or a moisture indicator such as cobalt chloride. When the test film 20 containing cobalt chloride is used, it is preferable that the non-woven fabric is pasted on the surface of the test film 20 that touches the skin so that the cobalt chloride does not touch the skin.

  According to the skin test patch 10 of this embodiment, the pH of the skin and the amount of water evaporation can be determined accurately. Knowing the amount of moisture evaporated from the skin and the pH helps to prevent skin troubles, and also in terms of beauty, knowing the exact skin condition helps to determine the care method. It is also possible to apply the skin test patch 10 directly to the skin and observe the change in pH over time. In addition, it is easy to manufacture, inexpensive and inexpensive.

  The skin test patch of the present invention is not limited to the above-described embodiments. For example, an indicator that reacts with body odor components emanating from the skin or an indicator that reacts with lipids on the skin surface is used. It is also possible to display the degree of body odor or to make a determination regarding body fat. In addition, the materials and shapes of the indicator and each member can be freely changed.

  Examples of the present invention will be described below. In this example, a film in which an indicator is contained in a test film is produced, and 5 parts of polyvinyl alcohol, 80 parts of purified water, 2 parts of glycerin, 3 parts of cobalt chloride (anhydride) and 10 parts of ethanol are uniformly distributed. Dissolve and mix, spread uniformly, and dry to form a test film 20 having a thickness of 30 μm. The inspection film 20 is cut into, for example, 5 mm × 10 mm and attached to the adhesive layer 16 of the base film 12. This completes the skin moisture test patch. In addition, it is preferable that a thin nonwoven fabric is pasted on the inspection film 20 on the surface that touches the skin because the moisture absorption speed is fast and cobalt chloride does not touch the skin.

  The method for using the skin test patch is to apply the surface of the test film 20 to the skin and leave it for a predetermined time, and then check the color of the test film 20 with the color sample 14 on its side, Know the amount of evaporation.

This example is for a skin pH test film. 5 parts of polyvinyl alcohol, 87.9 parts of purified water, 7 parts of glycerin, and 0.1 part of BCP (bromocresol purple) are uniformly dissolved and mixed. The test film 20 is formed by uniformly spreading and drying to ³ mg / cm ³ . The inspection film 20 is cut into, for example, 5 mm × 10 mm and attached to the adhesive layer 16 of the base film 12. This completes the skin pH test patch.

  The skin inspection patch is also used by applying the surface on the test film 20 side to the skin and leaving it for a predetermined time, and then comparing the color of the test film 20 with the color sample 14 on the side, Know the pH of the.

It is a front view of one embodiment of a patch for skin examination of this invention. It is a top view of the patch for skin inspection of this embodiment. It is a front view of the patch for skin inspection of other embodiment of this invention.

Explanation of symbols

DESCRIPTION OF SYMBOLS 10 Patch for skin inspection 12 Base film 14 Color sample 16 Adhesive layer 20, 22 Film 24 for inspection Indicator

Claims (4)

  An inspection film formed in the form of a film by forming an adhesive layer on one surface of a transparent base film and dissolving or dispersing an indicator that displays a predetermined skin state in a polymer resin having moisture permeability A skin characterized in that the test film is affixed to the adhesive layer of the base film, and the surface of the base film is provided with a color sample of a color to which the indicator reacts due to skin secretions. Inspection patch.   An adhesive layer is formed on one surface of a transparent base film, and an indicator for indicating a predetermined skin state is applied to a test film made of a moisture-permeable polymer resin. A patch for skin examination, which is affixed to a pressure-sensitive adhesive layer of a material film, and is provided with a color sample of a color in which the indicator reacts with skin secretions on the surface of the base film.   A pressure-sensitive adhesive layer is formed on one surface of a transparent base film, and a polymer resin test film having moisture permeability is impregnated with an indicator for indicating a predetermined skin state. A patch for skin examination, which is affixed to a pressure-sensitive adhesive layer of a material film, and is provided with a color sample of a color in which the indicator reacts with skin secretions on the surface of the base film. 4. The skin test patch according to claim 1, wherein the indicator is cobalt chloride or a pH indicator.

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