JP2004201613A - Growth improver for livestock - Google Patents
Growth improver for livestock Download PDFInfo
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- JP2004201613A JP2004201613A JP2002376341A JP2002376341A JP2004201613A JP 2004201613 A JP2004201613 A JP 2004201613A JP 2002376341 A JP2002376341 A JP 2002376341A JP 2002376341 A JP2002376341 A JP 2002376341A JP 2004201613 A JP2004201613 A JP 2004201613A
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- acid
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- improving agent
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- formic acid
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Abstract
【課題】嗜好性が良く、かつ発育改善効果の優れた家畜の発育改善剤を提供することを目的とする。
【解決手段】蟻酸および乳酸を含有する家畜の発育改善剤。
【選択図】 なしAn object of the present invention is to provide a livestock growth improving agent having good palatability and excellent growth improving effect.
A livestock growth improving agent containing formic acid and lactic acid.
[Selection diagram] None
Description
【０００１】
【発明の属する技術分野】
本発明は、家畜に給与する嗜好性の良好な発育改善剤に関する。
【０００２】
【従来の技術】
従来、有機酸を添加した飼料によって、家畜を飼育して生産性を向上させることは知られている。一方、有機酸のなかでも特に蟻酸を用いた場合は嗜好性が悪いことから、極めて少量の配合量の場合には若干のプラス効果が認められるが、配合量が増大するにつれて逆に体重増加が悪くなることも知られている。
このような蟻酸の嗜好性を改善する方法として蟻酸カルシウムまたは蟻酸マグネシウムからなる、若い成長期の豚および鶏における生産性増進剤が提案されている（特許文献１参照）。
しかしながら、この生産性増進剤においても未だ満足できるものではなかった。
【０００３】
【特許文献１】
特開昭６３−５２８４６号公報
【０００４】
【発明が解決しようとする課題】
そこで本発明者等は、従来から嗜好性の悪い蟻酸を用いて嗜好性が良好で、かつ優れた発育効果を有する発育改善剤について種々研究を重ねた結果、本発明を完成するに至った。
【０００５】
【課題を解決するための手段】
すなわち、本発明は、蟻酸および乳酸を含有する家畜の発育改善剤に関する。
【０００６】
【発明の実施の形態】
本発明の発育改善剤の有効成分である蟻酸と乳酸との配合割合は、蟻酸１に対して乳酸を０．１〜１００（重量比）、特に０．３〜１０（重量比）の範囲配合することが好ましい。また本発明の発育改善剤は、蟻酸および乳酸にプロピオン酸を併用することによってさらに嗜好性が向上する。このプロピオン酸の配合割合は特に制限されるものではないが、好ましくは蟻酸１に対し０．１〜５（重量比）の範囲が好適である。
さらに本発明の発育改善剤は、所望によりクエン酸、フマル酸、酪酸、リンゴ酸、酢酸等の他の有機酸を配合することもできる。
本発明の発育改善剤を調製する場合、ケイ酸等の賦形剤を適宜用いることもできる。
【０００７】
本発明の発育改善剤を家畜に給与する方法としては溶液として給与する方法、粉末状の発育改善剤を飼料と混合して給与する方法等が挙げられるが、特に飲水による不断給与が好ましい。給与する家畜としては、豚、牛、鶏等が挙げられる。
【０００８】
本発明の発育改善剤の給与量としては、蟻酸および乳酸の合計量として０．０５〜２重量％、特に０．１〜１重量％の範囲が好ましい。
【０００９】
【実施例】
次に本発明をさらに具体的に説明するために実施例を掲げるが、本発明は以下の実施例のみに限定されるものではない。
【００１０】
実施例１
蟻酸７５．０重量部および乳酸２５．０重量部を均一に混合して発育改善剤を調製した。
【００１１】
実施例２
蟻酸２５．０重量部および乳酸７５．０重量部を均一に混合して発育改善剤を調製した。
【００１２】
実施例３
蟻酸１６．７重量部、乳酸６６．６重量部およびプロピオン酸１６．７重量部を均一に混合して発育改善剤を調製した。
【００１３】
次に本発明の発育改善剤の嗜好性について試験を行った。
試験例１
豚（ＬＷ種、体重７kg）８頭を１区として設け、これらの豚に基礎飼料として人工乳前期飼料（「ハーブソフト」日清飼料株式会社製商品名）と実施例１〜３の発育改善剤を用いて有機酸の合計量としての濃度が０．２％になるように調整した飲水を７日間不断給与してその飲水量を調べた。なお比較のために飲水として水道水あるいは蟻酸水溶液（濃度０．２％）のみの場合を対照例として示す。その試験結果を示せば表１のとおりである。
【００１４】
【表１】
試験例２
鶏（レイヤー）１０羽を１区として設け、これらの鶏に基礎飼料として表２に示す無薬レイヤー用飼料を給与して孵化直後から４週間飼育した。その間試験開始から３週間後にサルモネラ エンテリティディス（ＳＥ）（Salmonella Enteritidis）を１羽あたり１０7ＣＦＵ経口投与した。またこの試験期間中実施例３で調製した発育改善剤を飲水に溶かして０．２％濃度に調整し、この飲水を不断給与した。
なお比較のために飲水のみを与え、他は前記と同様に試験した結果を対照例として示す。
４週間飼育後に解剖・採材し、肝臓中および盲腸内のＳＥ検出率および盲腸内容物中のＳＥ菌数を調べた。
次にその試験結果を示せば表３のとおりである。
【００１６】
【表２】
【表３】
実施例４
蟻酸３７．５重量部、乳酸１２．５重量部およびケイ酸５０．０重量部を均一に混合して粉末状の発育改善剤を調製した。この粉末状の発育改善剤を基礎飼料とする無薬人工乳前期飼料（「無薬前期」日清飼料株式会社製商品名）に０．２％および０．４％濃度（蟻酸および乳酸の合計量としての濃度）になるように添加した。
【００１９】
実施例５
蟻酸３７．５重量部および乳酸１２．５重量部を水５０．０重量部に溶解して液状の発育改善剤を調製した。この液状の発育改善剤を飲水に溶かして０．２％および０．４％濃度（蟻酸および乳酸の合計量としての濃度）の飲水に調整した。
【００２０】
実施例６
蟻酸８．４重量部、乳酸３３．２重量部およびプロピオン酸８．４重量部を水５０．０重量部に溶解して液状の発育改善剤を調製した。この液状の発育改善剤を水に加えて０．２％および０．４％濃度（蟻酸、乳酸およびプロピオン酸の合計量としての濃度）の飲水を調製した。
【００２１】
次に実施例４〜６で調製した発育改善剤を用いて豚の飼育試験を行った。
【００２２】
試験例２
豚（マイティーＬＷＤ）８頭を１区として設け、これらの豚に基礎飼料として無薬人工乳前期飼料（「無薬前期」日清飼料株式会社製商品名）と本発明の発育改善剤を有機酸の合計量としての濃度が０．２％および０．４％になるように基礎飼料および飲水を調整して、それぞれ不断給与を行い、２１日間飼育した。なお比較のために飲水として水道水を用いた場合を対照例として示す。その試験結果を示せば表４のとおりである。
【００２３】
【表４】
【発明の効果】
本発明の発育改善剤は、極めて嗜好性が良く、かつ発育改善効果にも優れている。[0001]
TECHNICAL FIELD OF THE INVENTION
The present invention relates to a growth improving agent having good palatability, which is fed to livestock.
[0002]
[Prior art]
Conventionally, it is known to raise livestock and improve productivity by using a feed to which an organic acid is added. On the other hand, among the organic acids, particularly when formic acid is used, the palatability is poor, so that a slight positive effect is observed in the case of a very small amount of the compounding agent. It is also known to get worse.
As a method for improving such palatability of formic acid, a productivity enhancer for young growing pigs and chickens comprising calcium formate or magnesium formate has been proposed (see Patent Document 1).
However, even this productivity enhancer has not been satisfactory.
[0003]
[Patent Document 1]
JP-A-63-52846
[Problems to be solved by the invention]
Thus, the present inventors have conducted various studies on a growth improving agent having good palatability and excellent growth effect using formic acid having low palatability, and as a result, the present invention has been completed.
[0005]
[Means for Solving the Problems]
That is, the present invention relates to a livestock growth improving agent containing formic acid and lactic acid.
[0006]
BEST MODE FOR CARRYING OUT THE INVENTION
The compounding ratio of formic acid and lactic acid, which are the active ingredients of the growth improving agent of the present invention, is such that lactic acid is mixed in a range of 0.1 to 100 (weight ratio), particularly 0.3 to 10 (weight ratio) with respect to 1 of formic acid. Is preferred. Moreover, the growth improving agent of the present invention further improves palatability by using propionic acid in combination with formic acid and lactic acid. The mixing ratio of the propionic acid is not particularly limited, but is preferably in the range of 0.1 to 5 (weight ratio) with respect to 1 of formic acid.
Further, the growth improving agent of the present invention may optionally contain other organic acids such as citric acid, fumaric acid, butyric acid, malic acid and acetic acid.
When preparing the growth improving agent of the present invention, an excipient such as silicic acid can be used as appropriate.
[0007]
Examples of the method of feeding the growth improving agent of the present invention to livestock include a method of feeding the solution as a solution, and a method of mixing and feeding a powdery growth improving agent with feed, and the constant feeding by drinking water is particularly preferable. Domestic animals to be fed include pigs, cows, chickens and the like.
[0008]
The amount of the growth improving agent of the present invention to be fed is preferably in the range of 0.05 to 2% by weight, particularly 0.1 to 1% by weight as the total amount of formic acid and lactic acid.
[0009]
【Example】
Next, the present invention will be described in more detail with reference to Examples, but the present invention is not limited to the following Examples.
[0010]
Example 1
A growth improving agent was prepared by uniformly mixing 75.0 parts by weight of formic acid and 25.0 parts by weight of lactic acid.
[0011]
Example 2
25.0 parts by weight of formic acid and 75.0 parts by weight of lactic acid were uniformly mixed to prepare a growth improving agent.
[0012]
Example 3
A growth improving agent was prepared by uniformly mixing 16.7 parts by weight of formic acid, 66.6 parts by weight of lactic acid, and 16.7 parts by weight of propionic acid.
[0013]
Next, a test was conducted on the palatability of the growth improving agent of the present invention.
Test example 1
Eight pigs (LW species, weight 7 kg) were set up as one section, and these pigs were used as a basic feed for artificial milk early-stage feed ("Herb Soft" manufactured by Nissin Feed Co., Ltd.) and the growth improvement of Examples 1-3 Drinking water adjusted so that the concentration as the total amount of the organic acid was 0.2% using the agent was continuously supplied for 7 days, and the amount of drinking water was examined. For comparison, a case where only tap water or formic acid aqueous solution (concentration: 0.2%) is used as drinking water is shown as a control example. Table 1 shows the test results.
[0014]
[Table 1]
Test example 2
Ten chickens (layers) were provided as one section, and these chickens were fed a feed for a drug-free layer shown in Table 2 as a basic feed and bred for 4 weeks immediately after hatching. Meanwhile, three weeks after the start of the test, Salmonella enteritidis (SE) (Salmonella Enteritidis) was orally administered at 10 7 CFU per bird. During this test period, the growth improving agent prepared in Example 3 was dissolved in drinking water to adjust the concentration to 0.2%, and the drinking water was fed without interruption.
For comparison, only drinking water was given, and the other test results were the same as those described above.
After breeding for 4 weeks, the animals were dissected and collected, and the detection rate of SE in the liver and cecum and the number of SE bacteria in cecal contents were examined.
Next, the test results are shown in Table 3.
[0016]
[Table 2]
[Table 3]
Example 4
A powdery growth improver was prepared by uniformly mixing 37.5 parts by weight of formic acid, 12.5 parts by weight of lactic acid and 50.0 parts by weight of silicic acid. 0.2% and 0.4% concentration (total of formic acid and lactic acid) in drug-free artificial milk pre-feed (trade name of Nisshin Feed Co., Ltd.) using this powdered growth improver as a basic feed (Concentration as an amount).
[0019]
Example 5
37.5 parts by weight of formic acid and 12.5 parts by weight of lactic acid were dissolved in 50.0 parts by weight of water to prepare a liquid growth improving agent. This liquid growth improving agent was dissolved in drinking water to adjust to 0.2% and 0.4% drinking water (concentration as the total amount of formic acid and lactic acid).
[0020]
Example 6
8.4 parts by weight of formic acid, 33.2 parts by weight of lactic acid and 8.4 parts by weight of propionic acid were dissolved in 50.0 parts by weight of water to prepare a liquid growth improving agent. The liquid growth improving agent was added to water to prepare drinking water having a concentration of 0.2% and 0.4% (concentration as a total amount of formic acid, lactic acid and propionic acid).
[0021]
Next, a breeding test of pigs was performed using the growth improving agents prepared in Examples 4 to 6.
[0022]
Test example 2
Eight pigs (Mighty LWD) were set up as one section, and these pigs were treated with a non-medicated artificial milk early-term feed ("Non-pre-medicated" Nisshin Feed Co., Ltd. product name) and a growth-improving agent of the present invention as a basic feed. The basal feed and drinking water were adjusted so that the concentration as the total amount of the acid was 0.2% and 0.4%, and each was fed without restriction, and reared for 21 days. For comparison, a case where tap water is used as drinking water is shown as a control example. Table 4 shows the test results.
[0023]
[Table 4]
【The invention's effect】
The growth improving agent of the present invention has extremely good palatability and also has an excellent growth improving effect.
Claims (3)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002376341A JP2004201613A (en) | 2002-12-26 | 2002-12-26 | Growth improver for livestock |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002376341A JP2004201613A (en) | 2002-12-26 | 2002-12-26 | Growth improver for livestock |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007273347A Division JP4832399B2 (en) | 2007-10-22 | 2007-10-22 | Livestock growth improver |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2004201613A true JP2004201613A (en) | 2004-07-22 |
Family
ID=32813831
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002376341A Pending JP2004201613A (en) | 2002-12-26 | 2002-12-26 | Growth improver for livestock |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2004201613A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2874324A1 (en) * | 2004-08-20 | 2006-02-24 | Ceva Sante Animale Sa | Composition, useful as a veterinary antibacterial product, comprises lactic acid and formic acid in an excipient |
| JP2021506340A (en) * | 2017-12-18 | 2021-02-22 | インテジェネ（プロプライアタリー）リミティド | Water additives and compositions |
-
2002
- 2002-12-26 JP JP2002376341A patent/JP2004201613A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2874324A1 (en) * | 2004-08-20 | 2006-02-24 | Ceva Sante Animale Sa | Composition, useful as a veterinary antibacterial product, comprises lactic acid and formic acid in an excipient |
| JP2021506340A (en) * | 2017-12-18 | 2021-02-22 | インテジェネ（プロプライアタリー）リミティド | Water additives and compositions |
| JP7354135B2 (en) | 2017-12-18 | 2023-10-02 | インテジェネ（プロプライアタリー）リミティド | Water additives and compositions |
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