JP2002087911A - Improved insecticidal composition - Google Patents

Abstract

PROBLEM TO BE SOLVED: To improve instability of a chloronicotinyl compound under an alkaline condition. SOLUTION: This improved insecticidal composition is characterized by comprising a chloronicotinyl compound and a phosphate represented by the formula: MH2PO4 (M is sodium or potassium) or its hydrate.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

The present invention relates to an improved insecticidal composition. More specifically, the present invention relates to an improved insecticidal composition containing a chloronicotinyl compound and a method for stabilizing the compound.

[0002]

2. Description of the Related Art Chloronicotinyl compounds belong to a new group of compounds having insecticidal activity and are also called neonicotinoid compounds.

[0003] In general, in an improved preparation of a pesticidally active compound, in order to improve the instability (promotion of decomposition) of the pesticide itself under certain conditions, the composition of the composition is changed, and the stabilizing agent is added to the preparation. Various means such as addition and pH adjustment have been attempted.

[0004]

The problem that imidacloprid (common name) having insecticidal activity belonging to the chloronicotinyl series compounds is unstable under alkaline conditions has been experienced under application conditions so far. Was known from. For example, it is said that when imidacloprid is used as a termite agent, the formulation is extremely unstable to the alkalinity of concrete when the formulation is applied under the conditions of laying under-floor concrete in a house.

The inventors of the present invention have conducted studies on the stabilization of chloronicotinyl compounds represented by imidacloprid under such alkaline conditions, and as a result, the formula MH ₂ PO ₄ (I) Among them, it has been discovered that the stabilization of a chloronicotinyl-based compound can be completely achieved by adding a phosphate or a hydrate thereof represented by M representing sodium or potassium.

Thus, the present invention provides an improved insecticidal composition comprising the chloronicotinyl compound and the phosphate of the formula (I) or a hydrate thereof.

The present invention also provides a method for stabilizing a chloronicotinyl compound, which comprises adding the phosphate of the formula (I) or a hydrate thereof to the chloronicotinyl compound. is there.

Hereinafter, the present invention will be described in more detail.

[0009]

BEST MODE FOR CARRYING OUT THE INVENTION As a specific example of the chloronicotinyl compound in the present invention, a general name: imidacloprid {chemical name: 1-[(6-chloro-3-pyridyl) methyl] -N-nitro-2- Imidazolidine {generic name: thiamethoxam} Chemical name: 3-[(2-chloro-5-thiazolyl) methyl] tetrahydro-5-methyl-N-nitro-4H-1,3,5-oxadiazine-4
-Imine}, Generic name: clothianidin {Chemical name: N-[(2-chloro-5-thiazolyl) methyl] -N'-methyl-N "-nitro-guanidine}, Generic name: Dinotefuran {Chemical name: N- Methyl-N'-nitro-N "-[(tetrahydro-3-furanyl) methyl] -guanidine and the like. However, the chloronicotinyl compound used in the present invention is not limited to these compounds, and the present invention is widely applied to other compounds belonging to the chloronicotinyl compound (or neonicotinoid compound). Applicable.

Representative examples of the phosphate of the formula (I) and its hydrate in the present invention include sodium dihydrogen phosphate, potassium dihydrogen phosphate, sodium dihydrogen phosphate dihydrate, Examples thereof include sodium dihydrogen phosphate monohydrate and potassium dihydrogen phosphate monohydrate.

The improved insecticidal composition of the present invention generally comprises the phosphate of formula (I) or a hydrate thereof in an amount of about 0.1 to 2 parts by weight per 1 part by weight of the chloronicotinyl compound. It can be prepared using However, this ratio can be changed as appropriate according to changes in the alkaline conditions of the application scene.

The improved insecticidal composition of the present invention can exhibit its properties, especially when used as termites.

[0013] The improved insecticidal composition of the present invention can be present in the form of commercially useful preparations or in the form of use prepared from these preparations. The phosphate (I) or a hydrate thereof may be mixed in situ in actual use.

The content of the chloronicotinyl compound and the phosphate of the formula (I) or the hydrate thereof in the commercially useful preparation or use form of the improved insecticidal composition of the present invention can be varied within a wide range. be able to. The total content of the chloronicotinyl compound and the phosphate of the formula (I) or a hydrate thereof is generally about 10 to 60% by weight, preferably about 2% by weight.
It can be in the range of 0 to 50% by weight.

[0015] The improved insecticidal composition of the present invention can be made into a usual pharmaceutical form, for example, a liquid, a water solvent, a suspension, a wettable powder, a foam, a granule, a granular wettable powder, microcapsules. And the like.

These preparations can be produced by a method known per se, for example, by adding a chloronicotinyl compound and the phosphate of the formula (I) or a hydrate thereof to a solvent or carrier, Some may be prepared by mixing with a surfactant, ie, a wetting and / or dispersing agent and / or a foam former.

As the solvent, for example, aromatic hydrocarbons (eg, xylene, toluene, alkylnaphthalene, etc.), chlorinated aromatic or chlorinated aliphatic hydrocarbons (eg, chlorobenzenes, ethylene chlorides, methylene chloride) ), Aliphatic hydrocarbons (eg, cyclohexane, etc., paraffins (eg, mineral oil fractions, etc.)), alcohols (eg, butanol, glycol and their ethers, esters, etc.), ketones (eg, acetone,
Examples include methyl ethyl ketone, methyl isobutyl ketone, cyclohexanone, etc., strong polar solvents (eg, N-methylpyrrolidone, dimethylformamide, dimethyl sulfoxide, etc.), water and the like.

As the carrier, for example, soil natural minerals (eg, kaolin, clay, talc, chalk, quartz, attapull guide, montmorillonite, diatomaceous earth, etc.), pulverized synthetic minerals (eg, highly dispersed silicic acid, alumina, silicate, etc.) ), Titanium dioxide, and water-soluble salts (eg, potassium chloride, ammonium sulfate, sodium sulfate, etc.).

Solid carriers for granules include, for example, ground and fractionated rocks (eg, calcite, marble, pumice, sepiolite, dolomite, etc.), synthetic granules of inorganic and organic powders, organic substances Fine particles (eg, from sawdust, coconut, corn cob, tobacco stem, etc.) can be mentioned.

Examples of the wetting agent and / or foaming agent include nonionic and anionic surfactants [eg, polyoxyethylene fatty acid esters, polyoxyethylene fatty acid alcohol ethers (eg, alkylaryl polyglycol ether, alkylsulfonic acid) Salt, alkyl sulfate, aryl sulfonate, etc.), dialkyl sulfosuccinate, etc.], and albumin hydrolysis products.

Examples of the dispersant include alkyl sulfate, polyoxyethylene alkyl ether sulfate, polyoxyethylene alkyl phenyl ether sulfate, polyoxyethylene benzyl (or styryl) phenyl (or phenylphenyl) ether sulfate, and polyoxyethylene polyether. Oxypropylene block polymer sulfate, paraffin (alkane)
Sulfonate, alkylbenzene sulfonate, mono- or dialkyl (C _3-6 ) naphthalenesulfonate, naphthalenesulfonate-formalin condensate, alkyl (C
_8-12) diphenyl ether disulfonate, lignin sulfonate, polyoxyethylene alkyl (C _8-12) phenyl ether sulfonates, polyoxyethylene alkyl (C _{12-1 8)} ether sulfosuccinic acid half esters, polyoxyethylene benzylated phenyl (or (Phenylphenyl) ether phosphate, polyoxyethylene / polyoxypropylene block polymer phosphate, methyl cellulose and the like.

Binders can also be used in the preparations (powder, granules, emulsions).
Carboxymethylcellulose, natural and synthetic polymers (eg, gum arabic, polyvinyl alcohol, polyvinyl acetate, etc.) and the like can be mentioned.

A coloring agent may be used. Examples of the coloring agent include inorganic pigments (eg, iron oxide, titanium oxide, Prussian blue, etc.), organic dyes such as alizarin dyes, azo dyes and metal phthalocyanine dyes. And furthermore, minor elements such as salts of metals such as iron, manganese, boron, copper, cobalt, molybdenum, zinc and the like.

Next, the effects of the improved insecticidal composition of the present invention will be described more specifically with reference to the following examples, but the present invention should not be limited to these examples.

[0025]

Example 1 Test for Improving Stability of Imidacloprid <Test Method> A phosphoric acid solution was placed in a 6.3 mL / φ4 cm container corresponding to spraying 5 L of a 200-fold diluted solution of imidacloprid 20% flowable solution per 1 m ^2. Two cases without addition of potassium hydrogen, 11 mg addition, 22 mg addition,
A total of 5 samples A to E with 33 mg added were prepared, 2 mL of water was added to one of them, 2 mL of a saturated calcium hydroxide aqueous solution was added to the remaining 4 cases, and incubation was performed at 50 ° C. The residual amount of imidacloprid was measured over time by HPLC. Similarly, the results of tests (samples F to I) performed using sodium dihydrogen phosphate instead of potassium dihydrogen phosphate are also shown. <Results> Tables 1 and 2 show the results.

[0026]

[Table 1]

[0027]

[Table 2]

Formulation Example 1 Imidacloprid drug substance (98%) 20.4% Newcargen FS-26 3.0% SAG-10 0.1% Rhodopol G 0.2% Propylene glycol 8.0% Sodium dihydrogen phosphate 5.0% water residue The above composition is mixed and pulverized to obtain a suspending agent. Formulation Example 2 Imidacloprid drug substance (98%) 20.4% Newcargen FS-21 5.0% SAG-10 0.1% Rhodopol G 0.2% Propylene glycol 8.0% Potassium dihydrogen phosphate 3.0 % Water Residue The above composition is mixed and pulverized to obtain a suspending agent. Formulation Example 3 Imidacloprid drug substance (98%) 10.2% Newcargen E-150 4.0% SAG-10 0.1% Rhodopol G 0.2% Propylene glycol 8.0% Potassium dihydrogen phosphate 10.0 % Water Residue The above composition is mixed and pulverized to obtain a suspending agent.

% In the above formulation examples is% by weight (parts)
Is shown. The components in each composition are as follows.

● New Cargen FS-26: a product of dioctyl sulfosuccinate and polyoxyethylene tristyryl phenyl ether manufactured by Takemoto Yushi Co., Ltd. ● New Cargen FS-26: a dioctyl sulfosuccinate manufactured by Takemoto Yushi Co., Ltd. Combination product of polyoxyethylene alkylphenyl ether and Newcalgen E-150: manufactured by Takemoto Yushi Co., Ltd., polyoxyethylene allyl phenyl ether formaldehyde condensate ● SAG-10: manufactured by Nippon Unicar Co., Ltd., silicon-based defoamer ● Rhodopol G: Xanthan gum, manufactured by Rhodia Nichika Corporation

[0031]

The improved insecticidal composition of the present invention exhibits excellent stability as shown in the examples.

Continued on the front page F-term (reference) 4H011 AC03 BA01 BA04 BB11 BC03 BC07 BC18 BC19 DA15 DD05 DH02 DH03 DH14

Claims (3)

[Claims] 1. An improved insecticidal composition comprising a chloronicotinyl compound and a phosphate or a hydrate thereof represented by the following formula MH ₂ PO _{4 wherein} M represents sodium or potassium. object. 2. The improved insecticidal composition according to claim 1, wherein the chloronicotinyl compound is imidacloprid (common name) or thiamethoxam (common name). 3. A chloronicotinyl-based compound characterized by adding a phosphate or a hydrate thereof represented by the following formula MH ₂ PO ₄ in which M represents sodium or potassium to the chloronicotinyl-based compound. Compound stabilization method.