JP2001278727A - Cosmetics - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a cosmetic composition having low irritation, less sticky feeling after use, suitable viscosity, and excellent stability at low temperatures without precipitation or cloudiness even at low temperatures. Get. SOLUTION: An N-acyl glutamate represented by the following formula (1) and xyloglucan are contained, and the pH of the cosmetic is 5 to 8. Embedded image

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a cosmetic composition having a low irritation, an excellent feeling upon use, a moderate viscosity and an excellent low-temperature stability. More specifically, N-acyl glutamate is used as a surfactant, and as a thickener,
By using xyloglucan and adjusting the pH of the aqueous solution to 5 to 8 when the solid content concentration of the cosmetic is adjusted to 10%, hypoallergenicity, less sticky feeling after use, and appropriate viscosity The present invention relates to a technique for obtaining a cosmetic having excellent low-temperature stability that does not cause cloudiness or precipitation even at low temperatures.

[0002]

2. Description of the Related Art Xyloglucan, which has been used as a food thickener, has a characteristic that, unlike other natural polysaccharides, it has a less sticky feeling even after being used in cosmetics. It has begun to be used as a thickener for cosmetics. Conventional technology related to xyloglucan for cosmetics uses xyloglucan as a moisturizing ingredient (sugars, polyhydric alcohols, sericin, etc.) and the stickiness after use when UV protection agents are added to cosmetics. (JP-A-10-167951, JP-A-11-152207, JP-A-10-259142),
A method of improving the feeling of use when a carboxyvinyl polymer is used as a thickener by adding xyloglucan (Japanese Patent Laid-Open No. 11-12155), and a method of reducing the viscosity decrease at a high temperature when using xyloglucan as a thickener. There is a method that can be solved by using another thickening polysaccharide in combination (Japanese Patent Laid-Open No. 10-259118).

[0003] These prior arts are aimed at obtaining a cosmetic composition which is less sticky and has excellent usability, or a cosmetic composition which is excellent in usability and has excellent high-temperature stability.
However, the required performance of cosmetics, which is more important than the feeling of use and high-temperature stability, is that they are hypoallergenic and have excellent low-temperature stability, and there is no useful solution to these problems. It was the current situation.

[0004]

DISCLOSURE OF THE INVENTION The present invention has low irritation, has little sticky feeling after use, has an appropriate viscosity,
Further, an object of the present invention is to provide a cosmetic excellent in low-temperature stability in which white turbidity and precipitation do not occur even at a low temperature.

[0005]

The present inventors have conducted intensive studies to solve the above-mentioned problems, and as a result, have found that N-
By using acyl glutamate, using xyloglucan as a thickener, and adjusting the pH of the aqueous solution to 5 to 8 when the solid content concentration of the cosmetic is adjusted to 10%,
The present inventors have found that the above-mentioned problems can be solved, and have reached the present invention.
That is, the present invention contains an N-acylglutamate represented by the following formula (1) as the component (a) and xyloglucan as the component (b), and reduces the solid content of the cosmetic to 10%.
And pH of the aqueous solution when adjusted to 5-8.

[0006]

Embedded image The surfactant used in the present invention is one or more of the N-acylglutamic acid salts represented by the above formula (1). The N-acyl glutamate represented by the above formula (1) is obtained by acylating L-glutamic acid with a fatty acid chloride or the like, and further adding a part of the carboxyl group of the glutamic acid portion with sodium hydroxide, potassium hydroxide, triethanolamine or the like. Or all of them are converted into sodium salts, potassium salts, triethanolamine salts, or the like.

Specific examples thereof include monosodium N-lauroylglutamate, disodium N-lauroylglutamate, monopotassium N-lauroylglutamate, dipotassium N-lauroylglutamate, monotriethanolamine N-lauroylglutamate, ditriethanolamine N-lauroylglutamate. Ethanolamine, monopotassium N-myristoylglutamate, dipotassium N-myristoylglutamate, monosodium N-myristoylglutamate, disodium N-myristoylglutamate, monotriethanolamine N-myristoylglutamate, ditriethanolamine N-myristoylglutamate, N-palmitoyl Monosodium glutamate, N-palmitoyl disodium glutamate, N-palmit Monopotassium Le glutamic acid, N-
Dipotassium palmitoylglutamate, monotriethanolamine N-palmitoylglutamate, ditriethanolamine N-palmitoylglutamate, monosodium N-stearoylglutamate, disodium N-stearoylglutamate, monopotassium N-stearoylglutamate, dipotassium N-stearoylglutamate, N- Monotriethanolamine stearoylglutamate, ditriethanolamine N-stearoylglutamate, disodium N-coconut fatty acid acylglutamate, monosodium N-coconut fatty acid acylglutamate, monopotassium N-coconut fatty acid acylglutamate, N-coconut fatty acid Dipotassium acylglutamate, N-coconut fatty acid acylglutamate monotriethanolamine N-coconut fatty acid acylglutamate ditriethanolamine, N-tallow fatty acid acylglutamate disodium, N-tallow fatty acid acylglutamate monosodium, N-tallow fatty acid acylglutamate monopotassium, N-tallow fatty acid acylglutamate monotriethanolamine, N -Dipotassium tallow fatty acid acylglutamate, ditriethanolamine N-tallow fatty acid acylglutamate and the like.

[0008] The xyloglucan used in the present invention is a main component of the seeds of tamarindas indica, a legume plant mainly produced in the tropics, and has a main chain composed of β-1,4-glucan and a side chain. Is a polysaccharide having a structure in which xylose and galactose are bonded and having a molecular weight of about 650,000.
Commercially available products include “Glyloid 6C” manufactured by Dainippon Pharmaceutical Co., Ltd. The weight ratio of the component (a) N-acyl glutamate and the component (b) xyloglucan in the cosmetic of the present invention is (a) / (b) = 100/1 to 1/10.
0 is preferable, and more preferably (a) / (b) = 50 /
It is 1/1/50, more preferably 30/1 to 1/30.

[0009] The above ratio by weight of the surfactant N
-If the amount of acyl glutamate is large, the sticky feeling after use tends to be strong. Further, if the N-acyl glutamate content is smaller than the above weight ratio, the surfactant activity (detergency, emulsifying power, solubilizing power, dispersing power, etc.) tends to be insufficient. In addition, when the amount of xyloglucan is larger than the above weight ratio, xyloglucan itself forms a film peculiar to the polymer, so that the feeling of use of the cosmetic is easily impaired. Also, if the amount of xyloglucan is smaller than the above weight ratio, the sticky feeling after using the cosmetic is likely to become strong.

The amount of the N-acyl glutamate of the component (a) is preferably 0.1% by weight to 90% by weight, more preferably 1% by weight to 50% by weight, based on the total amount of the cosmetic. If the amount is less than 0.1% by weight, the surfactant of the cosmetic tends to be insufficient. If the amount is more than 90% by weight, the sticky feeling after use tends to become strong. For the whole cosmetic,
The amount of xyloglucan as the component (b) is 0.1% by weight to 90%.
% By weight, more preferably 0.5% to 50% by weight, even more preferably 1% to 20% by weight.
If the amount is less than 0.1% by weight, the stickiness of the cosmetic is likely to be strong. If the content is more than 90% by weight, the feeling of use of the cosmetic is easily impaired.

The cosmetic of the present invention may optionally contain (c)
Ingredient water is blended. The amount of water relative to the total amount of the cosmetic is preferably 1% by weight to 90% by weight, more preferably 10% by weight.
% By weight to 70% by weight. If the amount of water is less than 1% by weight, the feeling of use of the cosmetic tends to deteriorate. Also, 9
If the amount is more than 0% by weight, the surface activity (detergency, emulsifying power, solubilizing power, dispersing power, etc.) of the cosmetic tends to deteriorate.
The cosmetic of the present invention can be in the form of a solid, powder, cream, liquid, gel, or the like, by adding the amount of component (c) water or the fourth component described below. .

The viscosity of the cosmetic of the present invention in the form of a liquid, cream, gel, etc., is 1 at 25 ° C.
It is preferable to be 0 mPa · s to 100000 mPa · s. More preferably, 100 mPa · s to 100
It is preferably 00 mPa · s. In addition, when the pH of the aqueous solution when the solid content concentration is adjusted to 10% is not 5 to 8, the cosmetic of the present invention is prepared by adding an appropriate amount of an acid or a base to adjust the pH of the aqueous solution having a solid content concentration of 10%. Is 5
８8. From a hypoallergenic perspective,
More preferably, the pH is adjusted from weakly acidic to neutral pH = 5-7.

The method for measuring the pH of cosmetics in the present invention varies depending on the solid content of the cosmetics. The solid content concentration of the cosmetic is 1
If it exceeds 0%, the pH is measured after adjusting the solid concentration to 10% by diluting with purified water. When the solid content of the cosmetic is less than 10%, the solid content is reduced to 10% by evaporating a liquid component such as water in the cosmetic.
After adjusting the pH, the pH is measured. By adjusting the pH of the aqueous solution to 5 to 8 when the solid concentration of the cosmetic of the present invention is adjusted to 10%, the cosmetic becomes less irritating, and even at low temperatures, problems such as precipitation, cloudiness, and separation occur. No cosmetics with excellent low-temperature stability can be obtained.

In the cosmetic of the present invention, if necessary, in addition to the above basic components, other components usually used in cosmetics may be added in a range that does not impair the performance of the cosmetic of the present invention. Can be blended. For example, a surfactant other than N-acyl glutamate may be further added.
The surfactant that can be blended is not particularly limited, and any of an anionic surfactant, a cationic surfactant, an amphoteric surfactant, and a nonionic surfactant can be blended.

Specific examples of the anionic surfactant include:
Fatty acid soaps such as potassium laurate and sodium laurate; higher alkyl sulfates such as sodium lauryl sulfate; N-coconut fatty acid acylglycine sodium; N-coconut fatty acid acylglycine potassium; N-coconut fatty acid acylglycine triethanol Amine, N-
N-acyl glycine salts such as sodium lauroyl glycine, N-lauroyl glycine triethanolamine, potassium N-lauroyl glycine, sodium N-coco oil fatty acyl sarcosine, potassium N-coco fatty acyl sarcosine, N-coco fatty fatty acyl sarcosine N-acyl sarcosine salts such as triethanolamine, potassium N-lauroyl sarcosine, sodium N-lauroyl sarcosine, N-lauroyl sarcosine triethanolamine, monosodium N-lauroyl aspartate, disodium N-lauroyl aspartate,
Dipotassium N-lauroylaspartate, monopotassium N-lauroylaspartate, monotriethanolamine N-lauroylaspartate, ditriethanolamine N-lauroylaspartate, monopotassium N-coconut fatty acid acyl monoaspartate, N-coconut fatty acid Monosodium acylaspartate, dipotassium N-coconut fatty acid acylaspartate, disodium N-coconut fatty acid acylaspartate, monotriethanolamine N-coconut fatty acid acylaspartate,
N-acyl aspartates such as N-coconut oil fatty acylaspartate ditriethanolamine, dipotassium N-lauroylalanine, monosodium N-lauroylalanine, disodium N-lauroylalanine, N
-Lauroylalanine monopotassium, N-lauroylalanine monotriethanolamine, N-lauroylalanine ditriethanolamine, N-coconut fatty acid acylalanine monopotassium, N-coconut fatty acid acylalanine dipotassium, N-coconut fatty acid acylalanine mono N-acylalanine salts such as sodium, N-coconut fatty acid acylalanine disodium, N-coconut fatty acid acylalanine ditriethanolamine, N-coconut fatty acid acylalanine monotriethanolamine;
Lauroyl beta alanine disodium, N-lauroyl beta
Alanine monosodium, N-lauroyl β-alanine monopotassium, N-lauroyl β-alanine dipotassium, N
-Lauroyl β-alanine monotriethanolamine, N
-Lauroyl β-alanine ditriethanolamine, N-
Coconut fatty acid acyl β-alanine monopotassium, N-coconut fatty acid acyl β-alanine dipotassium, N-coconut oil fatty acyl β-alanine monosodium, N-coconut fatty acid acyl β-alanine disodium, N-coconut fatty acid acyl β-alanine ditri N- such as ethanolamine, N-coconut fatty acid acyl β-alanine monotriethanolamine, etc.
Acyl β-alanine salt, N-lauroyl taurine monosodium, N-lauroyl taurine disodium, N-lauroyl taurine dipotassium, N-lauroyl taurine monopotassium, N-lauroyl taurine monotriethanolamine, N-lauroyl taurine ditriethanolamine, N -Dipotassium coconut fatty acid acyltaurine,
N-coconut fatty acid acyltaurine monopotassium, N-coconut fatty acid acyltaurine monosodium, N-coconut fatty acid acyltaurine disodium, N-coconut fatty acid acyltaurine monotriethanolamine, N-coconut fatty acid acyltaurine ditri N- such as ethanolamine
Acyl taurine salts and the like.

Specific examples of the cationic surfactant include:
Examples thereof include alkyl trimethyl ammonium salts such as lauryl trimethyl ammonium chloride, alkyl pyridinium salts such as lauryl pyridinium chloride, and benzalkonium chloride. Specific examples of the amphoteric surfactant include lauryl-N, N-dimethylaminoacetate betaine, coconut oil-N,
Betaine N-dimethylaminoacetate, myristyl-N, N
-Betaine dimethylaminoacetate, stearyl-N, N-
Betaine dimethylaminoacetate, betaine stearylamidopropyl-N, N-dimethylaminoacetate, betaine cocoamidopropyl-N, N-dimethylaminoacetate, betaine lauramidopropyl-N, N-dimethylaminoacetate, N-hydroxyethyl- Betaine-based surfactants such as N-carboxymethyl-2-laurylimidazolinium betaine and the like can be mentioned.

Specific examples of the nonionic surfactant include:
Polyoxyethylene alkyl ethers, polyoxypropylene alkyl ethers, sorbitan fatty acid esters, propylene glycol fatty acid esters, polyoxypropylene fatty acid esters, polyoxyethylene fatty acid esters, polyoxyethylene alkyl phenyl ethers, pluronic type And the like. If necessary, a thickening agent other than xyloglucan can be blended as long as the performance of the cosmetic of the present invention is not impaired. Thickeners that can be blended are not particularly limited, and guar gum, cationized guar gum, carrageenan, dextran, quince seed, sodium hyaluronate,
Natural polymer thickeners such as karaya gum, tragacanth gum, xanthan gum, and locust bingham; semi-synthetic polymer thickeners such as cationized cellulose, propylene glycol alginate, hydroxypropylmethylcellulose, sodium carboxymethylcellulose, and sodium alginate; polyvinylpyrrolidone , Polyvinyl alcohol, carboxyvinyl polymer and other synthetic high-molecular thickeners, polyoxyethylene dioleic acid methylglucoside, coconut oil diethanolamide, lauric acid isopropanolamide, non-polymeric thickeners such as polyethylene glycol distearate, Any of them can be blended.

In addition, hydrocarbons such as liquid paraffin, squalane, petrolatum, olive oil, rapeseed oil,
Linseed oil, fats and oils such as soybean oil, lauryl alcohol, myristyl alcohol, cetyl alcohol, alcohols such as stearyl alcohol, capric acid, myristic acid, lauric acid, palmitic acid, oleic acid, linoleic acid, fatty acids such as stearic acid, Humectants such as glycerin, polyethylene glycol, 1,3-butylene glycol, sorbitol, xylitol, maltitol, hyaluronic acid, and chitosan; antioxidants such as tocopherol, L-ascorbic acid, and butylhydroxytoluene; parahydroxybenzoate; Antibacterial agents such as sodium benzoate and hinokitiol, as well as ultraviolet absorbers, silicone derivatives, fragrances, dyes, and the like can be added.

The cosmetic of the present invention can be processed into a commonly used dosage form such as a solid, powder, cream, liquid, or gel by processing as necessary.

[0020]

DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, the present invention will be described in more detail by way of examples.

[0021]

Examples 1 to 6 Cosmetics having the composition shown in Table 1 were prepared and evaluated for the primary irritation (EYETEX) of the ocular mucosa, the stickiness after use, the viscosity at 25 ° C., and the stability at low temperatures. did. Incidentally, N-acylglutamate is N-coconut fatty acid acylglutamate monotriethanolamine,
N-coconut fatty acid disodium acylglutamate, N
-Dipotassium coconut oil fatty acyl glutamate was used. Glyloid 6C from Dainippon Pharmaceutical Co., Ltd. was used for xyloglucan.

A 30% aqueous solution of triethanolamine, a 30% aqueous solution of sodium hydroxide, a 30% aqueous solution of potassium hydroxide, and a 30% aqueous solution of citric acid as pH adjusting liquids are manufactured by Wako Pure Chemical Industries, Ltd. using special grade triethanolamine and special grade water. It was prepared by diluting sodium oxide, special grade potassium hydroxide and special grade citric acid monohydrate with purified water. The purified water for dilution and the purified water to be added to the cosmetic used were those manufactured by Wako Pure Chemical Industries, Ltd.

The evaluation items, primary irritation of eye mucosa (EYET)
EX) is a 3% solids aqueous solution of each cosmetic.
Ir made by INVITRO INTERNATIONAL
writing Assay System Oc
ullar Surfactanat Protocol
Tested. The pH of each cosmetic was measured after adjusting the solid content of the cosmetic of the present invention to 10% by adding water or evaporating a liquid component such as water.

<Evaluation criteria for primary irritation of ocular mucosa> ：: Minimal (Irritancy Score)
Is 0 to 15) Δ: Mild (Irritancy Score is 15)
× 30) ×: Moderate (Irritancy Score)
e is 30 to 50) In the test of the sticky feeling after use, 30 people judged each cosmetic. <Evaluation Criteria of Sticky Feeling> 未 満: Less than 5 people felt sticky △: 5 or more and less than 10 people felt sticky ×: 10 or more people felt sticky 25 The viscosity at ° C was measured with a B-type viscometer manufactured by Tokyo Keiki Co., Ltd. In the low-temperature stability test, each cosmetic described in Table 1 was stored at 5 ° C. for one week, and the appearance of the cosmetic was visually determined. <Low Temperature Stability Evaluation Criteria> 透明: Transparent ×: Cloudy or precipitate is precipitated.

[0025]

Comparative Examples 1 to 6 Cosmetics having the compositions shown in Table 2 were prepared.
The primary irritation (EYETEX) of the ophthalmic mucosa of the cosmetic, the degree of stickiness after use, the viscosity at 25 ° C, and the low-temperature stability were evaluated. The surfactant used was sodium lauryl sulfate manufactured by Wako Pure Chemical Industries, Ltd., and the potash soap used was Alhome K-100 manufactured by Shin Nippon Rika Co., Ltd. The thickener hydroxypropyl methylcellulose used was Metroose 65SH- manufactured by Shin-Etsu Chemical Co., Ltd.
4000 was used and PVA224C manufactured by Kuraray Co., Ltd. was used as polyvinyl alcohol. The other raw materials used were the same as in the examples. The evaluation method and evaluation criteria were also the same as those in the examples.

[0026]

[Table 1]

[0027]

[Table 2]

[0028]

Industrial Applicability According to the present invention, it is possible to obtain a cosmetic composition which has low irritation, has a low sticky feeling after use, has an appropriate viscosity, and has excellent low-temperature stability without causing cloudiness or precipitation even at low temperatures. .

Claims (5)

[Claims] 1. An N-acyl glutamate represented by the following formula (1) as a component (a) and xyloglucan as a component (b), and the solid content of the cosmetic is 10%.
%, Wherein the pH of the aqueous solution when adjusted to 5% is 5 to 8. Embedded image 2. The weight ratio of component (a) N-acylglutamate to component (b) xyloglucan is (a) /
2. The cosmetic according to claim 1, wherein (b) = 100/1 to 1/100. 3. The cosmetic according to claim 1, further comprising water as the component (c). 4. The cosmetic according to claim 3, wherein the content of the component (c) is 1 to 90% by weight based on the whole cosmetic. 5. A viscosity at 25 ° C. of 10 to 10,000.
The pressure is 0 mPa · s.
Or the cosmetic according to 4.