JP2000005136A - Temperature measuring device and implant - Google Patents

Abstract

(57) [Summary] The object of the present invention is to eliminate a lead wire in a measuring instrument for measuring in-vivo information, receive radio waves transmitted from an oscillator to obtain information, and simultaneously obtain local information by irradiating an external electromagnetic field. An object of the present invention is to provide a heatable indwelling minimal implant and a temperature measuring device. According to one embodiment, a temperature sensor includes an oscillator configured using a transistor whose output signal has a temperature-dependent characteristic, a transmission device configured to transmit a signal output from the temperature sensor, and A power supply circuit 3 for supplying power to the temperature sensor 1 and the transmitting device 2 is formed as an implant 10 housed in a capsule-shaped case 11, and the implant 10 is embedded in a living body.
And an implant 10 for receiving a signal output from the transmitter 2 of the present invention.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a temperature measuring device applicable to an electronic thermometer and the like, and a medical implant having a function of transmitting temperature information in a living body to outside the body.

[0002]

2. Description of the Related Art Conventionally, in temperature measurement represented by cancer hyperthermia, an invasive temperature measurement method in which a thermocouple thermometer or an optical fiber thermometer is directly inserted into a treatment site in a body has been implemented. Since these methods measure the temperature by inserting a sensor from outside the body into a temperature measurement site, the state in which the lead wire is kept attached even during the treatment period is unpleasant for the patient. On the other hand, as a non-invasive temperature measurement method, multi-frequency radiometry that receives weak electromagnetic waves emitted from the living body itself has been studied, but with extremely difficult technology,
It has not yet been put to practical use. In particular, in the hyperthermia treatment for cancer using electromagnetic waves or ultrasonic irradiation, strict temperature control of the treatment site (usually 42.5 ° C.) is required. In a thermometer with a lead wire using a conventional thermocouple as a sensor,
There is a problem that an irradiation electromagnetic field often affects this lead wire and degrades a temperature indicating characteristic. In the current cancer hyperthermia, the inability to perform sufficient temperature measurement, deep heating, and local heating has become a major technical barrier and has been stagnant.

[0003]

SUMMARY OF THE INVENTION An object of the present invention is to eliminate a lead wire in a measuring instrument for measuring in-vivo information, receive radio waves transmitted from an oscillator to obtain information, and simultaneously obtain an external electromagnetic field. An object of the present invention is to provide an indwelling minimal implant that can be locally heated by irradiation and a temperature measuring device.

Another object of the present invention is to solve the problems of temperature measurement and local heating among the technical problems of hyperthermia. For example, the present invention relates to an implant and a temperature measuring method that removes a lead wire that can be used semipermanently during a treatment period or during follow-up as long as it is once placed in the body in temperature measurement such as during cancer hyperthermia treatment. It relates to a measuring device. Here, the embodiment of the system for measuring the body temperature as the biological information in the present invention is described. However, the present invention measures other biological information such as blood flow and blood glucose level, and also detects an external magnetic field. And an implant that can be heated by electric field irradiation. That is, the present invention provides a medical information implant of a system in which frequency information output from an integrated oscillator using a monolithic microwave integrated circuit (MMIC) is output from a living body by radio waves and the radio waves are received outside the body. According to the present invention, a conductive lead wire that picks up noise, which has been a problem of this type of measuring instrument, can be eliminated, and accurate measurement and discomfort of a patient can be eliminated.

[0005]

According to a first aspect of the present invention, there is provided a temperature measuring device, wherein the temperature sensor is an oscillator including a transistor, and the temperature sensor has a frequency of an output signal. A temperature-dependent characteristic, wherein the temperature sensor, a transmission device for transmitting a signal output from the temperature sensor, and a power supply circuit for supplying power to the temperature sensor and the transmission device are capsule-shaped cases The implant is formed as an implant stored in a living body, and the implant is embedded in a living body, and is configured from an in vitro receiving device that receives a signal output from a transmitting device of the implant and the implant. is there.

[0006] The temperature measuring device of claim 2 is claim 1.
In the temperature measurement device described above, the power supply circuit converts magnetic field energy of a magnetic field emitted from outside the living body into electric energy and supplies power to the temperature sensor and the transmission device.

[0007] The temperature measuring device of claim 3 is claim 1.
Or in the temperature measuring device according to 2, the temperature sensor is a voltage-controlled oscillator whose oscillation frequency can be controlled by a DC power supply, forms another temperature sensor on the outer surface or a part of the implant, and is output from the another temperature sensor. A power supply voltage depending on the signal is supplied from the power supply circuit to the temperature sensor.

[0008] A temperature measuring device according to a fourth aspect is the temperature measuring device according to the first, second or third aspect, wherein the transmitting device is constituted by an antenna. According to a fifth aspect of the present invention, in the temperature measuring apparatus of the fourth aspect, the antenna is formed on a part of the outer or inner surface of the implant case, or on the entire outer or inner surface. is there.

A temperature measuring device according to a sixth aspect of the present invention is the temperature measuring device according to the first, second or third aspect, wherein a part or the whole of the implant case is formed of a magnetic material. .

The implant according to claim 7 is a biological information sensor for measuring biological information, a transmitting device for transmitting a signal from the biological information sensor, and a power supply for supplying power to the biological information sensor and the transmitting device. It is characterized by having.

The implant according to claim 8 includes a temperature sensor for measuring a temperature, a transmitting device for transmitting a signal from the temperature sensor, and a power supply for supplying power to the temperature sensor and the transmitting device. It is characterized by the following.

[0012] The implant according to claim 9 is an implant according to claim 8.
In the implant described above, as the temperature sensor, a temperature sensor including an oscillator configured using a transistor whose output signal frequency exhibits temperature-dependent characteristics is used.

According to a tenth aspect of the present invention, in the implant of the eighth aspect, a power source for converting magnetic field energy into electric energy is used as a power source.

According to an eleventh aspect of the present invention, in the implant according to the eighth aspect, a transmitting device including an antenna is used as the transmitting device.

According to the first aspect of the present invention, a medical implant having an oscillator whose free oscillation frequency changes with temperature as a temperature sensor is formed and embedded in a body.
The living body temperature information (oscillation frequency) detected by the temperature sensor propagates from the inside of the living body via the transmitting device and is transmitted outside the living body, and the information can be detected by the outside living body receiver. That is, temperature information in the living body can be detected only by observing the frequency fluctuation of the temperature sensor provided in the implant by the receiver outside the living body. Therefore, a lead wire is not required unlike a conventional temperature measuring device using a thermocouple as a sensor. In addition, in the case of an internal thermometer required for cancer hyperthermia, etc., when a lead wire is used, it is dangerous to pierce a living body deeply, near the brain, or near the heart, and medical treatment is required. It was difficult. However, according to the first aspect of the present invention, since an implant that also serves as a temperature measurement can be embedded without being restricted by the location and depth of a cancer tumor site, it is possible to treat a diseased site that has been difficult in the past. . In addition, since the temperature of the cancer tumor can be accurately monitored by placing the implant that also serves as a temperature measurement in the cancer tumor, the killing effect of the cancer cell by the hyperthermia can be enhanced. Further, the invention according to claim 1 does not require another signal source for transmitting temperature information to the outside of the body unlike the conventional temperature measuring device because the temperature sensor is constituted by an oscillator. As a result, circuits such as a signal source and an amplifier can be omitted, so that there is an advantage that the implant can be realized with a small size, low cost, and a simple configuration. In addition, a temperature sensor, a power supply circuit, and a transmission device are connected to a monolithic microwave circuit (MMI).
By using the technique C), it is possible to further reduce the size of the implant, and to realize a temperature measuring device having excellent uniformity and reproducibility. Furthermore, if the outer surface of the implant placed in the body is configured to generate heat by applying a magnetic field from outside the body, local heat therapy can be performed safely while monitoring the temperature information by causing the implant to also generate heat. .

The present invention according to claim 2 provides the present invention according to claim 1.
In addition to the object of the invention according to the present invention, the power supply circuit converts the magnetic field energy of the magnetic field emitted from outside the body into electric energy, and creates a power supply voltage to be supplied to the temperature sensor and the transmission device. Becomes unnecessary. Therefore, the power supply circuit is simplified, and the size and weight of the implant can be reduced. Further, since there is no limitation due to the service life of the battery, the service life of the implant to be placed in the living body can be extended.

The present invention according to claim 3 provides claim 1
In addition to the object of the invention, the temperature sensor is constituted by a voltage-controlled oscillator whose oscillation frequency can be controlled by a DC power supply, so that the modulation sensitivity of the temperature sensor can be improved. Further, another temperature sensor is formed on the outer surface or a part of the implant, and a power supply voltage dependent on a signal output from the another temperature sensor is supplied to the temperature sensor from the power supply circuit. Observation of temperature becomes possible. Further, by providing another sensor capable of detecting information in a living body in place of another temperature sensor provided on the outer surface or a part of the implant, it becomes possible to measure information such as blood flow and blood glucose level.

The present invention according to claim 4 is based on claim 1.
In addition to the object of the invention according to the above, since the transmitting device is formed by an antenna, power supply to the transmitting device is not required. Therefore, the size and weight of the implant can be reduced, and the service life can be extended.

According to a fifth aspect of the present invention, a first aspect is provided.
In addition to the object of the invention according to the present invention, since the antenna serving as the transmitting device is formed on the surface of the implant, further downsizing of the implant can be realized.

[0020]

DESCRIPTION OF THE PREFERRED EMBODIMENTS Embodiments of the present invention will be described below in detail with reference to the drawings. [First Embodiment] FIG. 1 shows a first embodiment of a temperature measuring apparatus according to the present invention.

In FIG. 1, reference numeral 1 denotes a temperature sensor. The temperature sensor 1 is connected to a transmitting device 2. A power supply required to drive the temperature sensor 1 and the transmitting device 2 is a power supply circuit 3.
Supplied by Here, the temperature sensor 1 is an oscillator formed using transistors, and the power supply circuit 3
Is partially or entirely constituted by a battery 4. The temperature sensor 1, the transmitting device 2 and the power supply circuit 3 are stored inside a case 11 made of an insulator, and an implant 10 is formed. The implant 10 is buried in the body, and measures the in-vivo temperature at the indwelling position with the temperature sensor 1.
Is detected, and a signal having a frequency dependent on the detected temperature is detected by the sensor 1.
It is oscillated and output. The signal output from the temperature sensor 1 is radiated from the implant 10 via the transmitting device 2,
The signal propagated outside the body through the living body is received by the receiving device 20.
To receive. Since the body temperature can be observed based on the frequency of the signal detected by the receiving device 20, the device is configured as a temperature measuring device.

According to the first embodiment described above, since the oscillator whose oscillation frequency changes with temperature is used as a temperature sensor, the frequency fluctuation output from the implant can be observed by a receiver outside the body. Thereby, the temperature information in the living body can be detected. Therefore, a lead wire is not required unlike a conventional temperature measuring device using a thermocouple as a sensor.
In addition, in the case of an internal thermometer required for cancer hyperthermia, etc., when a lead wire is used, it is dangerous to pierce a living body deeply, near the brain, or near the heart, and medical treatment is required. It was difficult. However, in the invention according to the first embodiment,
Since an implant that also serves as a temperature measurement can be embedded without being restricted by the location and depth of a cancer tumor site, it is possible to treat a diseased site, which was difficult in the past. In addition, since the temperature of the cancer tumor can be accurately monitored by placing the implant that also serves as a temperature measurement in the cancer tumor, the killing effect of the cancer cell by the hyperthermia can be enhanced. Also, since the temperature sensor is composed of an oscillator,
Unlike a conventional temperature measuring device, another signal source for transmitting temperature information outside the living body is not required, so that a signal source and a circuit such as an amplifier are not required, and the implant can be realized with a small and simple configuration. Further, the temperature sensor 1, the power supply circuit 3 and the transmission device 2 are connected to a monolithic microwave circuit (MMIC).
By using the technology, it is possible to realize a temperature measuring device that can achieve further downsizing of the implant and also has excellent uniformity and reproducibility. Further, by forming a part of the implant case 11 using a magnetic material, heat is generated due to eddy current loss of the magnetic material due to magnetic field irradiation from outside the body, and local hyperthermia is performed while monitoring temperature information. it can.

FIG. 6 shows an example of an oscillator used for a temperature sensor of the temperature measuring device according to the first embodiment of the present invention. The transistor is a bipolar transistor (C. Yamagu)
chi, Y .; Kobayashi, M .; Miyake,
K. Ishii, and H .; Ichino, “0.5
-Μm Bipolar Transistor Us
ing a New Base Formation
Method: SST1C, "IEEE 1993 B
ipolar Circuits and Techn
logic Meeting 4.2, pp. 6-6
6. ) Was used.

That is, as shown in FIG. 6, the base voltage supply terminal T1 is connected to the base B of the transistor TR via the resistor R1, and the base B of the transistor TR is connected to the grounded capacitor C1 via the transmission line L1. Connected to
A resistor R2 is connected between the base B and the emitter E of the transistor TR. The emitter E of the transistor TR is grounded via a transmission line L2 and grounded via a capacitor C2. The collector C of the transistor TR
Is connected to one end of a capacitor C4 via a transmission line L3, and the other end of the capacitor C4 is connected to an output terminal T2. One end of the capacitor C4 is connected to a collector voltage supply terminal T3 via a transmission line L4, and the collector voltage supply terminal T3 is grounded via a capacitor C3.

FIG. 7 is a graph showing the relationship between the temperature of the oscillator shown in FIG. 6 and the oscillation frequency. According to FIG.
In the temperature range of に お い て 50 ° C., the oscillation frequency of the oscillator changes linearly with the temperature, which proves that the oscillator shown in FIG. In addition, the modulation sensitivity of the oscillation frequency to a temperature of about 42.5 ° C. required for cancer hyperthermia is constant, and the body temperature is accurately measured.
The cancer cell killing effect of the hyperthermia can be improved. Further, since the modulation sensitivity to temperature can be increased by changing the transistor size and the circuit configuration, the temperature measurement sensitivity can be improved. [Second Embodiment] FIG. 2 shows a second embodiment of the temperature measuring apparatus according to the present invention. 2, the same components as those in FIG. 1 are denoted by the same reference numerals.

In FIG. 2, reference numeral 1 denotes a temperature sensor. The temperature sensor 1 is connected to a transmitting device 2. A power supply required for driving the temperature sensor 1 and the transmitting device 2 is a power supply circuit 3.
Supplied by Here, the temperature sensor 1 is an oscillator formed using transistors, and the power supply circuit 3
Is constituted by a converter 5 for rectifying a magnetic field emitted from outside the living body and converting the rectified magnetic field into a DC power supply. The temperature sensor 1, the transmitting device 2, and the power supply circuit 3 are stored inside a case 11 made of an insulator, and an implant 10 is formed. The implant 10 is embedded in the body,
The temperature sensor 1 detects the temperature in the living body at the indwelling position,
A signal having a frequency depending on the detected temperature is oscillated and output from the sensor 1. The signal output from the temperature sensor 1 is radiated from the implant 10 via the transmitting device 2, and the signal transmitted to the outside of the body through the living body is received by the receiving device 20. According to the frequency of the signal detected by the receiving device 20,
Since the body temperature can be observed, it is configured as a temperature measuring device.

According to the above-described second embodiment, in addition to the same effect as the first embodiment of the present invention, a DC power supply can be generated at any time by the converter 5, so that a battery is not required in the implant. As a result, the size and weight of the implant can be reduced, and the useful life of the implant to be placed in the living body can be increased. In the second embodiment, the case 11 is formed of an insulator.
A part or outer surface thereof may be formed of a magnetic material. Third Embodiment FIG. 3 shows a third embodiment of the temperature measuring apparatus according to the present invention. 3, the same components as those in FIG. 1 are denoted by the same reference numerals.

In FIG. 3, reference numeral 1 denotes a temperature sensor. The temperature sensor 1 is connected to a transmitting device 2. A power supply required to drive the temperature sensor 1 and the transmitting device 2 is a power supply circuit 3.
Supplied by Here, the temperature sensor 1 is an oscillator formed using a transistor, and has a power supply voltage supply terminal 7 capable of controlling an oscillation frequency. Also,
Part or all of the power supply circuit 3 is constituted by a battery 4. The temperature sensor 1, the transmitting device 2, and the power supply circuit 3 are stored inside a case 11 made of a capsule-shaped insulator, and an implant 10 is formed. Another temperature sensor 1 is provided on the outer surface of the case 11 of the implant 10.
2 are formed. The implant 10 is buried in the living body, and the temperature sensor 1 and the temperature sensor 12 detect the temperature of the living body at the indwelling position, and the sensor 1 oscillates and outputs a signal having a frequency depending on the detected temperature. Here, the temperature information detected by the temperature sensor 12 is transmitted to the controller 6, and the controller 6 is supplied from the power supply circuit 3 to the temperature sensor 1 through the power supply voltage supply terminal 7 based on the temperature information obtained from the temperature sensor 12. Voltage. The signal output from the temperature sensor 1 is radiated from the implant 10 via the transmitting device 2, and the signal transmitted to the outside of the body through the living body is received by the receiving device 20. Receiver 2
Since the body temperature can be observed based on the frequency of the signal detected from 0, the apparatus is configured as a temperature measuring device.

According to the third embodiment, the same effects as those of the first embodiment of the present invention can be obtained. Further, in addition to the temperature sensor 1, the temperature of the living body is detected by the temperature sensor 12 formed on the outer surface or a part of the implant 10, so that the measurement accuracy can be improved. Further, since the control voltage applied to the temperature sensor 1 as the oscillator is adjusted based on the temperature information detected by the temperature sensor 12, the modulation sensitivity of the oscillation frequency with respect to the temperature can be increased. That is, even when the temperature sensor 1 in which the free oscillation frequency fluctuates little with respect to the temperature is used, the control voltage applied to the temperature sensor 1 is controlled based on the information detected by the temperature sensor 12 to detect the biological temperature. Can be performed with high accuracy. Further, by providing another sensor capable of detecting information in a living body in place of the temperature sensor 12 provided on the outer surface or a part of the implant 10, biological information such as blood flow and blood glucose level can be measured.

FIG. 8 is a graph showing the relationship between the free oscillation frequency and the base supply voltage of the oscillator shown in FIG.
FIG. 8 shows that the oscillation frequency of the oscillator shown in FIG. 6 has high linearity with respect to the base supply voltage, and thus can operate as the temperature sensor 1 of the temperature measuring device of the third embodiment. [Fourth Embodiment] FIG. 4 shows a fourth embodiment of the temperature measuring apparatus according to the present invention. 4, the same components as those in FIG. 1 are denoted by the same reference numerals.

In FIG. 4, reference numeral 1 denotes a temperature sensor. The temperature sensor 1 is connected to an antenna 8, and power required for driving the temperature sensor 1 is supplied by a power supply circuit 3. Here, the temperature sensor 1 is an oscillator formed using a transistor, and a part or all of the power supply circuit 3 is configured by a battery 4. The temperature sensor 1, the antenna 8, and the power supply circuit 3 are stored inside a case 11 made of an insulator, and an implant 10 is formed. The implant 10 is buried in the body, and the temperature sensor 1 detects the temperature in the living body at the indwelling position, and the sensor 1 oscillates and outputs a signal having a frequency depending on the detected temperature. The signal output from the temperature sensor 1 is radiated from the implant 10 via the antenna 8, and the signal transmitted to the outside of the body through the living body is received by the receiving device 20. Since the body temperature can be observed based on the frequency of the signal detected by the receiving device 20, the device is configured as a temperature measuring device.

According to the above-described fourth embodiment, the same effects as those of the first embodiment of the present invention can be obtained. In addition, since the signal output from the temperature sensor 1 is directly radiated by the antenna 8, the configuration of the implant 10 is extremely simplified, and the required battery 4 can be reduced.
Therefore, the useful life of the implant 10 placed in the body can be extended. [Fifth Embodiment] FIG. 5 shows a fifth embodiment of the temperature measuring apparatus according to the present invention. 5, the same components as those in FIG. 1 are denoted by the same reference numerals.

In FIG. 5, reference numeral 1 denotes a temperature sensor, and power required for driving the temperature sensor 1 is supplied by a power supply circuit 3. Here, the temperature sensor 1 is an oscillator formed using a transistor, and a part or all of the power supply circuit 3 is configured by a battery 4. The temperature sensor 1 and the power supply circuit 3 are housed inside a case 11 made of an insulator, and an implant 10 is formed. An antenna 8 ′ is formed on the outer surface of the case 11 of the implant 10, and the antenna 8 ′ is connected to an output terminal of the temperature sensor 1. The above implant 1
In the case of 0, the temperature sensor 1 detects the temperature inside the living body at the position where the temperature is buried in the body, and the sensor is oscillated and output from the sensor 1 at a frequency dependent on the detected temperature. The signal output from the temperature sensor 1 is transmitted to the implant 10 via the antenna 8 '.
The receiving device 20 receives a signal radiated from the body and propagated outside the body through the living body. Since the temperature of the body can be observed based on the frequency of the signal detected by the receiving device 20,
It is configured as a temperature measuring device.

According to the fifth embodiment, the same effects as those of the fourth embodiment of the present invention can be obtained. Moreover, since the antenna 8 'is formed on the outer surface of the case 11 of the implant, the implant 10 can be made smaller. In the fifth embodiment, the antenna 8 'is formed on the outer surface of the case 11, but the same effect can be obtained by forming the antenna 8' on a part or the inner surface of the case.

[0035]

As described above, according to the present invention, an implant using an oscillator whose free oscillation frequency changes with temperature is formed as a temperature sensor and is placed in the body, so that it is detected by the temperature sensor. The transmitted biological temperature information (oscillation frequency) propagates from the inside of the living body via the transmitting device and is transmitted outside the living body, and the information can be detected by the extracorporeal receiver. That is, in-vivo temperature measurement can be performed by measuring only the frequency fluctuation received by the receiving device outside the body. As a result, a biological information measuring device that also functions as an indwelling-type heating element without a lead wire, which is necessary in a conventional temperature measuring device, that is, an implant can be formed, and widely used in cancer hyperthermia therapy and general medical treatment. Of course, it can be applied industrially. Particularly in the hyperthermia for cancer using strong electromagnetic waves, the problem that irradiation electromagnetic waves are coupled to a lead wire attached to a conventional temperature sensor, noise is generated, and accurate temperature display cannot be obtained can be solved. In addition, since the output signal of the temperature sensor depends on the temperature at the position where the implant is placed, the temperature of the cancer tumor can be accurately monitored by placing the implant in the tumor, thereby enhancing the lethal effect of the cancer cells. be able to.

Further, since the temperature sensor is composed of an oscillator, there is no need for another signal source for transmitting temperature information outside the body unlike a conventional temperature measuring device. Therefore, unnecessary circuits such as an amplifier can be omitted, and the implant can be reduced in size and realized with a simple configuration. Also, temperature sensors,
By configuring the power supply circuit and the transmission device using monolithic microwave circuit (MMIC) technology, it is possible to further reduce the size of the implant, and achieve uniformity,
A temperature measuring device with excellent reproducibility can be realized.

Further, since the outer surface or a part of the case of the implant to be placed in the body is made of a magnetic material, heat is generated by irradiation of a magnetic field from outside the body, so that local hyperthermia can be performed while monitoring the temperature information. .

In addition, in the case of cancer hyperthermia treatment, a magnetic field radiated from outside the body is rectified in the implant and a power supply voltage to be supplied thereby is generated, thereby eliminating the need for a battery. Therefore, the size and weight of the implant can be reduced and the service life can be extended.

In addition, by forming the antenna for transmitting the signal of the temperature sensor on the surface or a part of the case of the implant, the structure of the case stored in the case is simplified, and the size of the implant can be further reduced. .

The present invention is effective not only for cancer hyperthermia but also as a general medical technique by utilizing the fact that the sensitizing effect of the drug can be enhanced by appropriately heating the treatment site. . In that case, it is possible to measure not only the temperature information but also other biological information such as blood flow and blood glucose level once it is left in the body, and it is possible to perform regular medical examination and treatment based on such information .

[Brief description of the drawings]

FIG. 1 is a configuration explanatory view showing a temperature measuring device according to a first embodiment of the present invention.

FIG. 2 is a configuration explanatory view showing a temperature measuring device according to a second embodiment of the present invention.

FIG. 3 is a configuration explanatory view showing a temperature measuring device according to a third embodiment of the present invention.

FIG. 4 is a configuration explanatory view showing a temperature measuring device according to a fourth embodiment of the present invention.

FIG. 5 is a configuration explanatory view showing a temperature measuring device according to a fifth embodiment of the present invention.

FIG. 6 is a circuit diagram showing an oscillator configured using a silicon bipolar transistor as an example of a temperature sensor of the temperature measuring device according to the first embodiment of the present invention.

7 is a characteristic diagram illustrating an example of a relationship between an oscillation frequency and a temperature of the oscillator illustrated in FIG. 6;

8 is a characteristic diagram illustrating an example of a relationship between an oscillation frequency and a base supply voltage of the oscillator illustrated in FIG. 6;

[Description of Signs] 1, 12 Temperature sensor 2 Transmitting device 3 Power supply circuit 4 Battery 5 Converter 6 Controller 7 Power supply voltage supply terminal 8, 8 'Antenna 10 Implant 11 Implant case 20 Receiving device

 ──────────────────────────────────────────────────続 き Continued on the front page (72) Inventor Masayoshi Tanaka 3-19-2 Nishi-Shinjuku, Shinjuku-ku, Tokyo Japan Telegraph and Telephone Corporation (72) Inventor Yoji Kozuka 1117 Kitanagane, Hiratsuka-shi, Kanagawa Pref. University F term (reference) 2F056 AE01 AE05 AE07 2F073 AA02 AB02 AB12 AB14 BB02 BC02 CC02 CC15 CD01 DD01 DE01 EE11 FF02 GG01 GG02 GG09

Claims (11)

[Claims] 1. An oscillator in which a temperature sensor is configured using a transistor, wherein the temperature sensor exhibits a characteristic in which the frequency of an output signal depends on temperature, and the temperature sensor outputs an output signal from the temperature sensor. A transmitting device for transmitting a signal to be transmitted, and the power supply circuit for supplying power to the temperature sensor and the transmitting device are formed as an implant stored in a capsule-shaped case, the implant is embedded in a living body, and the A temperature measuring device, comprising: an in vitro receiving device that receives a signal output from a transmitting device; and the implant. 2. The temperature measuring device according to claim 1, wherein
A temperature measuring device, wherein a power supply circuit converts magnetic field energy of a magnetic field emitted from outside a living body into electric energy and supplies power to a temperature sensor and a transmitting device. 3. The temperature measuring device according to claim 1, wherein the temperature sensor is a voltage-controlled oscillator whose oscillation frequency can be controlled by a DC power supply, and another temperature sensor is formed on an outer surface or a part of the implant, A temperature measuring device, wherein a power supply voltage dependent on a signal output from the another temperature sensor is supplied to the temperature sensor from a power supply circuit. 4. The temperature measuring device according to claim 1, wherein the transmitting device comprises an antenna. 5. The temperature measuring device according to claim 4, wherein
A temperature measuring device, wherein the antenna is formed on a part of the outer or inner surface of the implant case, or on the entire outer or inner surface. 6. The temperature measuring device according to claim 1, wherein a part or the whole of the implant case is formed of a magnetic material. 7. A biological information sensor for measuring biological information, a transmitting device for transmitting a signal from the biological information sensor, and a power supply for supplying power to the biological information sensor and the transmitting device. Implant. 8. An implant, comprising: a temperature sensor for measuring a temperature; a transmitting device for transmitting a signal from the temperature sensor; and a power supply for supplying power to the temperature sensor and the transmitting device. 9. The implant according to claim 8, wherein the temperature sensor is a temperature sensor including an oscillator configured using a transistor whose output signal frequency exhibits a temperature-dependent characteristic. 10. The implant according to claim 8, wherein a power source for converting magnetic field energy into electric energy is used as the power source. 11. The implant according to claim 8, wherein a transmission device including an antenna is used as the transmission device.