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ITRM20050032A1 - Inibitori ed antagonisti di hmgb1 in grado di inibire la patogenesi e la progressione della malattia aterosclerotica. - Google Patents

Inibitori ed antagonisti di hmgb1 in grado di inibire la patogenesi e la progressione della malattia aterosclerotica.

Info

Publication number
ITRM20050032A1
ITRM20050032A1 IT000032A ITRM20050032A ITRM20050032A1 IT RM20050032 A1 ITRM20050032 A1 IT RM20050032A1 IT 000032 A IT000032 A IT 000032A IT RM20050032 A ITRM20050032 A IT RM20050032A IT RM20050032 A1 ITRM20050032 A1 IT RM20050032A1
Authority
IT
Italy
Prior art keywords
hmgb1
antagonists
progression
inhibitors
aterosclerotic
Prior art date
Application number
IT000032A
Other languages
English (en)
Inventor
Marco E Bianchi
Roberta Palumbo
Annalisa Porto
Original Assignee
Marco E Bianchi
Bio3 Res S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Marco E Bianchi, Bio3 Res S R L filed Critical Marco E Bianchi
Priority to IT000032A priority Critical patent/ITRM20050032A1/it
Priority to PCT/IT2006/000027 priority patent/WO2006077614A1/en
Publication of ITRM20050032A1 publication Critical patent/ITRM20050032A1/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IT000032A 2005-01-21 2005-01-21 Inibitori ed antagonisti di hmgb1 in grado di inibire la patogenesi e la progressione della malattia aterosclerotica. ITRM20050032A1 (it)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IT000032A ITRM20050032A1 (it) 2005-01-21 2005-01-21 Inibitori ed antagonisti di hmgb1 in grado di inibire la patogenesi e la progressione della malattia aterosclerotica.
PCT/IT2006/000027 WO2006077614A1 (en) 2005-01-21 2006-01-18 Hmgb1 inhibitors and antagonists for the inhibition of atherosclerosis pathogenesis and development

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000032A ITRM20050032A1 (it) 2005-01-21 2005-01-21 Inibitori ed antagonisti di hmgb1 in grado di inibire la patogenesi e la progressione della malattia aterosclerotica.

Publications (1)

Publication Number Publication Date
ITRM20050032A1 true ITRM20050032A1 (it) 2006-07-22

Family

ID=36218422

Family Applications (1)

Application Number Title Priority Date Filing Date
IT000032A ITRM20050032A1 (it) 2005-01-21 2005-01-21 Inibitori ed antagonisti di hmgb1 in grado di inibire la patogenesi e la progressione della malattia aterosclerotica.

Country Status (2)

Country Link
IT (1) ITRM20050032A1 (it)
WO (1) WO2006077614A1 (it)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2009240884B8 (en) 2008-04-30 2014-03-06 Genomix Co., Ltd. Agent for recruitment of bone-marrow-derived pluripotent stem cell into peripheral circulation
RU2571230C2 (ru) 2008-04-30 2015-12-20 Дженомикс Ко., Лтд. Способ сбора функциональных клеток in vivo с высокой эффективностью
AU2010312537A1 (en) 2009-10-28 2012-05-17 Genomix Co., Ltd. Tissue-regeneration promoter using recruitment of bone marrow mesenchymal stem cells and/or pluripotent stem cells in blood
PL2703487T3 (pl) 2011-04-26 2019-03-29 StemRIM Inc. Peptyd do indukowania regeneracji tkanki i jego stosowanie
TR201802122T4 (tr) 2012-10-25 2018-03-21 Genomix Co Ltd HMGB1 fragmanı kullanarak kardiyak infarksiyonun tedavisine yönelik yeni yöntem.
TR201807769T4 (tr) 2012-10-25 2018-06-21 Genomix Co Ltd HMGB1 fragmanı kullanılarak spinal kord yaralanmasının tedavi edilmesine yönelik yeni yöntem.
KR102559262B1 (ko) 2017-01-27 2023-07-25 가부시키가이샤 스템림 심근증, 진구성 심근경색 및 만성심부전의 치료약
US11298403B2 (en) 2017-12-01 2022-04-12 StemRIM Inc. Therapeutic agent for inflammatory bowel disease
US12304933B2 (en) 2018-10-05 2025-05-20 StemRIM Inc. Disease treatment drug based on mesenchymal-stem-cell mobilization

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7151082B2 (en) * 1999-02-11 2006-12-19 The Feinstein Institute For Medical Research Antagonists of HMG1 for treating inflammatory conditions
US6303321B1 (en) * 1999-02-11 2001-10-16 North Shore-Long Island Jewish Research Institute Methods for diagnosing sepsis
US7754217B2 (en) * 2001-03-16 2010-07-13 Bio3 Research Srl HMGB1 protein inhibitors and/or antagonists for the treatment of vascular diseases

Also Published As

Publication number Publication date
WO2006077614A1 (en) 2006-07-27

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