ITMI910491A0 - IMMONOTOXIN FROM ANTI-CDS MONOCLONAL ANTIBODIES - Google Patents
IMMONOTOXIN FROM ANTI-CDS MONOCLONAL ANTIBODIESInfo
- Publication number
- ITMI910491A0 ITMI910491A0 IT91MI491A ITMI910491A ITMI910491A0 IT MI910491 A0 ITMI910491 A0 IT MI910491A0 IT 91MI491 A IT91MI491 A IT 91MI491A IT MI910491 A ITMI910491 A IT MI910491A IT MI910491 A0 ITMI910491 A0 IT MI910491A0
- Authority
- IT
- Italy
- Prior art keywords
- immonotoxin
- monoclonal antibodies
- cds
- cds monoclonal
- antibodies
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6849—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
- A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
- A61K47/6817—Toxins
- A61K47/6819—Plant toxins
- A61K47/6825—Ribosomal inhibitory proteins, i.e. RIP-I or RIP-II, e.g. Pap, gelonin or dianthin
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Botany (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI910491A IT1249051B (en) | 1991-02-26 | 1991-02-26 | IMMUNOTOXIN FROM ANTI-CD5 MONOCLONAL ANTIBODIES |
AU12088/92A AU1208892A (en) | 1991-02-26 | 1992-02-18 | Immunotoxin from anti-cd5 monoclonal antibodies |
PCT/EP1992/000338 WO1992014491A1 (en) | 1991-02-26 | 1992-02-18 | Immunotoxin from anti-cd5 monoclonal antibodies |
EP92904825A EP0577612A1 (en) | 1991-02-26 | 1992-02-18 | Immunotoxin from anti-cd5 monoclonal antibodies |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI910491A IT1249051B (en) | 1991-02-26 | 1991-02-26 | IMMUNOTOXIN FROM ANTI-CD5 MONOCLONAL ANTIBODIES |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI910491A0 true ITMI910491A0 (en) | 1991-02-26 |
ITMI910491A1 ITMI910491A1 (en) | 1992-08-26 |
IT1249051B IT1249051B (en) | 1995-02-11 |
Family
ID=11358745
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI910491A IT1249051B (en) | 1991-02-26 | 1991-02-26 | IMMUNOTOXIN FROM ANTI-CD5 MONOCLONAL ANTIBODIES |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0577612A1 (en) |
AU (1) | AU1208892A (en) |
IT (1) | IT1249051B (en) |
WO (1) | WO1992014491A1 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6146850A (en) * | 1991-11-04 | 2000-11-14 | Xoma Corporation | Proteins encoding gelonin sequences |
US5837491A (en) * | 1991-11-04 | 1998-11-17 | Xoma Corporation | Polynucleotides encoding gelonin sequences |
US5621083A (en) * | 1991-11-04 | 1997-04-15 | Xoma Corporation | Immunotoxins comprising ribosome-inactivating proteins |
AU2018374283A1 (en) | 2017-11-29 | 2020-06-04 | Magenta Therapeutics, Inc. | Compositions and methods for the depletion of CD5+ cells |
JP2022530026A (en) | 2019-04-24 | 2022-06-27 | ハイデルベルク ファルマ リサーチ ゲゼルシャフト ミット ベシュレンクテル ハフツング | Amatoxin antibody drug conjugate and its use |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4363799A (en) * | 1979-03-20 | 1982-12-14 | Ortho Pharmaceutical Corporation | Monoclonal antibody to human T cells, and methods for preparing same |
FR2577135B1 (en) * | 1985-02-13 | 1989-12-15 | Sanofi Sa | LONG-TERM ACTION IMMUNOTOXINS COMPRISING A GLYCOPEPTITIDE CONSTITUENT MODIFYING RIBOSOMES MODIFIED ON ITS POLYSACCHARIDE PATTERNS |
EP0214995B1 (en) * | 1985-03-04 | 1990-12-27 | Dana Farber Cancer Institute | Immunotoxin and method of making |
US4831122A (en) * | 1986-01-09 | 1989-05-16 | Regents Of The University Of Minnesota | Radioimmunotoxins |
EP0397798A4 (en) * | 1988-02-03 | 1991-10-30 | Xoma Corporation | Therapeutic use of anti-t cell immunotoxin for autoimmune diseases |
EP0407399A4 (en) * | 1988-02-03 | 1991-06-19 | Xoma Corporation | Immunosupression with anti-pan t-cell immunotoxin compositions |
WO1989011871A1 (en) * | 1988-06-01 | 1989-12-14 | Cetus Corporation | One-step chromatographic purification of immunotoxin conjugates using a thiophilic matrix |
-
1991
- 1991-02-26 IT ITMI910491A patent/IT1249051B/en active IP Right Grant
-
1992
- 1992-02-18 EP EP92904825A patent/EP0577612A1/en not_active Withdrawn
- 1992-02-18 AU AU12088/92A patent/AU1208892A/en not_active Abandoned
- 1992-02-18 WO PCT/EP1992/000338 patent/WO1992014491A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO1992014491A1 (en) | 1992-09-03 |
IT1249051B (en) | 1995-02-11 |
EP0577612A1 (en) | 1994-01-12 |
AU1208892A (en) | 1992-09-15 |
ITMI910491A1 (en) | 1992-08-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19960227 |