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ITMI20120786A1 - MODULATORS OF THE GPR17 RECEPTOR - Google Patents

MODULATORS OF THE GPR17 RECEPTOR

Info

Publication number
ITMI20120786A1
ITMI20120786A1 IT000786A ITMI20120786A ITMI20120786A1 IT MI20120786 A1 ITMI20120786 A1 IT MI20120786A1 IT 000786 A IT000786 A IT 000786A IT MI20120786 A ITMI20120786 A IT MI20120786A IT MI20120786 A1 ITMI20120786 A1 IT MI20120786A1
Authority
IT
Italy
Prior art keywords
modulators
gpr17 receptor
gpr17
receptor
Prior art date
Application number
IT000786A
Other languages
Italian (it)
Inventor
Maria Pia Abbracchio
Mario Alberto Battaglia
Ivano Eberini
Marta Fumagalli
Chiara Parravicini
Cristina Sensi
Paola Zaratin
Original Assignee
Fond Italiana Sclerosi M Ultipla Fism Onlu
Univ Degli Studi Milano
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fond Italiana Sclerosi M Ultipla Fism Onlu, Univ Degli Studi Milano filed Critical Fond Italiana Sclerosi M Ultipla Fism Onlu
Priority to IT000786A priority Critical patent/ITMI20120786A1/en
Publication of ITMI20120786A1 publication Critical patent/ITMI20120786A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12—Oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
IT000786A 2012-05-09 2012-05-09 MODULATORS OF THE GPR17 RECEPTOR ITMI20120786A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IT000786A ITMI20120786A1 (en) 2012-05-09 2012-05-09 MODULATORS OF THE GPR17 RECEPTOR

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000786A ITMI20120786A1 (en) 2012-05-09 2012-05-09 MODULATORS OF THE GPR17 RECEPTOR

Publications (1)

Publication Number Publication Date
ITMI20120786A1 true ITMI20120786A1 (en) 2013-11-10

Family

ID=46466668

Family Applications (1)

Application Number Title Priority Date Filing Date
IT000786A ITMI20120786A1 (en) 2012-05-09 2012-05-09 MODULATORS OF THE GPR17 RECEPTOR

Country Status (1)

Country Link
IT (1) ITMI20120786A1 (en)

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2373186A (en) * 2001-02-23 2002-09-18 Astrazeneca Ab Pharmaceutical combinations of a CCR3 antagonist and a compound which is usefulreatment of asthma, allergic disease or inflammation
WO2004030611A2 (en) * 2002-08-23 2004-04-15 Ribapharm Inc. Non-nucleoside reverse transcriptase inhibitors
WO2004089416A2 (en) * 2003-04-11 2004-10-21 Novo Nordisk A/S Combination of an 11beta-hydroxysteroid dehydrogenase type 1 inhibitor and an antihypertensive agent
WO2005033102A2 (en) * 2003-10-03 2005-04-14 Amphora Discovery Corporation Thiophene-based compounds exhibiting atp-utilizing enzyme inhibitory activity, and compositions, and uses thereof
WO2005087750A1 (en) * 2004-03-08 2005-09-22 Wyeth Ion channel modulators
WO2007008541A2 (en) * 2005-07-08 2007-01-18 Kalypsys, Inc. Cellular cholesterol absorption modifiers
WO2007061923A2 (en) * 2005-11-18 2007-05-31 Takeda San Diego, Inc. Glucokinase activators
KR20090053560A (en) * 2007-11-23 2009-05-27 재단법인서울대학교산학협력재단 HsK0 inhibitors containing 1,2,4-triazole derivatives and anticancer agents using the same
EP2286808A1 (en) * 2009-08-18 2011-02-23 Rheinische Friedrich-Wilhelms Universität Cytohesin inhibitors
US20110212994A1 (en) * 2009-06-26 2011-09-01 Brian Clem Small Molecule Choline Kinase Inhibitors, Screening Assays, and Methods for Safe and Effective Treatment of Neoplastic Disorders

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2373186A (en) * 2001-02-23 2002-09-18 Astrazeneca Ab Pharmaceutical combinations of a CCR3 antagonist and a compound which is usefulreatment of asthma, allergic disease or inflammation
WO2004030611A2 (en) * 2002-08-23 2004-04-15 Ribapharm Inc. Non-nucleoside reverse transcriptase inhibitors
WO2004089416A2 (en) * 2003-04-11 2004-10-21 Novo Nordisk A/S Combination of an 11beta-hydroxysteroid dehydrogenase type 1 inhibitor and an antihypertensive agent
WO2005033102A2 (en) * 2003-10-03 2005-04-14 Amphora Discovery Corporation Thiophene-based compounds exhibiting atp-utilizing enzyme inhibitory activity, and compositions, and uses thereof
WO2005087750A1 (en) * 2004-03-08 2005-09-22 Wyeth Ion channel modulators
WO2007008541A2 (en) * 2005-07-08 2007-01-18 Kalypsys, Inc. Cellular cholesterol absorption modifiers
WO2007061923A2 (en) * 2005-11-18 2007-05-31 Takeda San Diego, Inc. Glucokinase activators
KR20090053560A (en) * 2007-11-23 2009-05-27 재단법인서울대학교산학협력재단 HsK0 inhibitors containing 1,2,4-triazole derivatives and anticancer agents using the same
US20110212994A1 (en) * 2009-06-26 2011-09-01 Brian Clem Small Molecule Choline Kinase Inhibitors, Screening Assays, and Methods for Safe and Effective Treatment of Neoplastic Disorders
EP2286808A1 (en) * 2009-08-18 2011-02-23 Rheinische Friedrich-Wilhelms Universität Cytohesin inhibitors

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
IVANO EBERINI ET AL: "In silico identification of new ligands for GPR17: a promising therapeutic target for neurodegenerative diseases", JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN, KLUWER ACADEMIC PUBLISHERS, DO, vol. 25, no. 8, 9 July 2011 (2011-07-09), pages 743 - 752, XP019955577, ISSN: 1573-4951, DOI: 10.1007/S10822-011-9455-8 *
PARK ET AL: "Discovery of novel alpha-glucosidase inhibitors based on the virtual screening with the homology-modeled protein structure", BIOORGANIC & MEDICINAL CHEMISTRY, PERGAMON, GB, vol. 16, no. 1, 1 January 2008 (2008-01-01), pages 284 - 292, XP022485949, ISSN: 0968-0896, DOI: 10.1016/J.BMC.2007.09.036 *
PATRICK MARKT ET AL: "Discovery of Novel CB 2 Receptor Ligands by a Pharmacophore-Based Virtual Screening Workflow", JOURNAL OF MEDICINAL CHEMISTRY, vol. 52, no. 2, 22 January 2009 (2009-01-22), pages 369 - 378, XP055034823, ISSN: 0022-2623, DOI: 10.1021/jm801044g *
PATRICK MARKT ET AL: "Discovery of Novel PPAR Ligands by a Virtual Screening Approach Based on Pharmacophore Modeling, 3D Shape, and Electrostatic Similarity Screening", JOURNAL OF MEDICINAL CHEMISTRY, vol. 51, no. 20, 23 October 2008 (2008-10-23), pages 6303 - 6317, XP055035029, ISSN: 0022-2623, DOI: 10.1021/jm800128k *

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