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ITMI20021532A1 - CHEMICAL COMPOUNDS - Google Patents

CHEMICAL COMPOUNDS

Info

Publication number
ITMI20021532A1
ITMI20021532A1 IT2002MI001532A ITMI20021532A ITMI20021532A1 IT MI20021532 A1 ITMI20021532 A1 IT MI20021532A1 IT 2002MI001532 A IT2002MI001532 A IT 2002MI001532A IT MI20021532 A ITMI20021532 A IT MI20021532A IT MI20021532 A1 ITMI20021532 A1 IT MI20021532A1
Authority
IT
Italy
Prior art keywords
chemical compounds
compounds
chemical
Prior art date
Application number
IT2002MI001532A
Other languages
Italian (it)
Inventor
Roberto Pellicciari
Original Assignee
Roberto Pellicciari
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roberto Pellicciari filed Critical Roberto Pellicciari
Priority to IT2002MI001532A priority Critical patent/ITMI20021532A1/en
Priority to PCT/EP2003/007512 priority patent/WO2004007521A2/en
Priority to AU2003250935A priority patent/AU2003250935A1/en
Publication of ITMI20021532A1 publication Critical patent/ITMI20021532A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Obesity (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
IT2002MI001532A 2002-07-12 2002-07-12 CHEMICAL COMPOUNDS ITMI20021532A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
IT2002MI001532A ITMI20021532A1 (en) 2002-07-12 2002-07-12 CHEMICAL COMPOUNDS
PCT/EP2003/007512 WO2004007521A2 (en) 2002-07-12 2003-07-11 Bile acid derivatives as agonists of the farnesoid x receptor
AU2003250935A AU2003250935A1 (en) 2002-07-12 2003-07-11 Bile acid derivatives as agonists of the farnesoid x receptor

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2002MI001532A ITMI20021532A1 (en) 2002-07-12 2002-07-12 CHEMICAL COMPOUNDS

Publications (1)

Publication Number Publication Date
ITMI20021532A1 true ITMI20021532A1 (en) 2004-01-12

Family

ID=30012506

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2002MI001532A ITMI20021532A1 (en) 2002-07-12 2002-07-12 CHEMICAL COMPOUNDS

Country Status (3)

Country Link
AU (1) AU2003250935A1 (en)
IT (1) ITMI20021532A1 (en)
WO (1) WO2004007521A2 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2440680C (en) 2001-03-12 2010-06-01 Roberto Pellicciari Steroids as agonists for fxr
EP1568706A1 (en) 2004-02-26 2005-08-31 Intercept Pharmaceuticals, Inc. Novel steroid agonist for FXR
US10987362B2 (en) 2004-03-12 2021-04-27 Intercept Pharmaceuticals, Inc. Treatment of fibrosis using FXR ligands
EP2712617B2 (en) 2004-03-12 2020-11-18 Intercept Pharmaceuticals, Inc. Treatment of fibrosis using Fxr ligands
US7618956B2 (en) 2005-05-31 2009-11-17 The Gillette Company Reduction of hair growth
WO2008091540A2 (en) 2007-01-19 2008-07-31 Intercept Pharmaceuticals, Inc. 23-substituted bile acids as tgr5 modulators and methods of use thereof
US8338628B2 (en) * 2007-08-28 2012-12-25 City Of Hope Method of synthesizing alkylated bile acid derivatives
US8796249B2 (en) 2008-07-30 2014-08-05 Intercept Pharmaceuticals, Inc. TGR5 modulators and methods of use thereof
PL2698375T3 (en) 2008-11-19 2018-08-31 Intercept Pharmaceuticals, Inc. TGR5 modulators and method of use thereof
PT3336097T (en) 2012-06-19 2020-10-29 Intercept Pharmaceuticals Inc Preparation of the non-crystalline form of obeticholic acid
US9982008B2 (en) 2012-06-19 2018-05-29 Intercept Pharmaceuticals, Inc. Preparation and uses of obeticholic acid
ME03082B (en) * 2013-05-14 2019-01-20 Intercept Pharmaceuticals Inc 11-HYDROXYL-6-SUBSTITUTED-Bile ACID DERIVATIVES AND THEIR AMINO ACID CONJUGATES AS FARNEZOID H RECEPTOR MODULATORS
US9895380B2 (en) 2013-09-11 2018-02-20 Inserm (Institut National De La Sante Et De La Recherche Medicale) Methods and pharmaceutical compositions for the treatment of hepatitis B virus infection
CN104672290B (en) * 2015-01-05 2017-06-06 北京普禄德医药科技有限公司 A kind of medicine of disease for preventing or treating FXR mediations and its production and use
MX382537B (en) 2017-02-21 2025-03-13 Genfit Combination of a ppar agonist with a fxr agonist
JP2020515564A (en) 2017-03-30 2020-05-28 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル Methods and pharmaceutical compositions for reducing episomal virus persistence and expression
WO2019085963A1 (en) * 2017-11-02 2019-05-09 正大天晴药业集团股份有限公司 Method for preparing cholic acid compound
KR20220035365A (en) 2019-07-18 2022-03-22 엔요 파마 How to reduce the side effects of interferon
ES3014367T3 (en) 2020-01-15 2025-04-22 Inst Nat Sante Rech Med Use of fxr agonists for treating an infection by hepatitis d virus
CA3204800A1 (en) 2021-01-14 2022-07-21 Raphael Darteil Synergistic effect of a fxr agonist and ifn for the treatment of hbv infection
EP4329761A1 (en) 2021-04-28 2024-03-06 ENYO Pharma Strong potentiation of tlr3 agonists effects using fxr agonists as a combined treatment

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1223313B (en) * 1987-10-20 1990-09-19 Gipharmex Spa BILIARY ACID DERIVATIVES THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
IT1229570B (en) * 1989-04-17 1991-09-04 Giuliani Spa FLUORATED DERIVATIVES OF BILIARY ACIDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
CA2440680C (en) * 2001-03-12 2010-06-01 Roberto Pellicciari Steroids as agonists for fxr

Also Published As

Publication number Publication date
WO2004007521A2 (en) 2004-01-22
AU2003250935A1 (en) 2004-02-02
AU2003250935A8 (en) 2004-02-02
WO2004007521A3 (en) 2004-04-01

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