ITMI20020269A1 - USE OF OMEGA-3 POLYUNSATURATED ACID ETHYL STERES IN PATIENTS WITH HEART INSUFFICIENCY - Google Patents
USE OF OMEGA-3 POLYUNSATURATED ACID ETHYL STERES IN PATIENTS WITH HEART INSUFFICIENCYInfo
- Publication number
- ITMI20020269A1 ITMI20020269A1 IT2002MI000269A ITMI20020269A ITMI20020269A1 IT MI20020269 A1 ITMI20020269 A1 IT MI20020269A1 IT 2002MI000269 A IT2002MI000269 A IT 2002MI000269A IT MI20020269 A ITMI20020269 A IT MI20020269A IT MI20020269 A1 ITMI20020269 A1 IT MI20020269A1
- Authority
- IT
- Italy
- Prior art keywords
- steres
- omega
- patients
- acid ethyl
- heart insufficiency
- Prior art date
Links
- 206010019280 Heart failures Diseases 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 125000001495 ethyl group Chemical class [H]C([H])([H])C([H])([H])* 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
- A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2002MI000269A ITMI20020269A1 (en) | 2002-02-12 | 2002-02-12 | USE OF OMEGA-3 POLYUNSATURATED ACID ETHYL STERES IN PATIENTS WITH HEART INSUFFICIENCY |
| AU2003210210A AU2003210210A1 (en) | 2002-02-12 | 2003-02-05 | The use of omega-3 polyunsaturated acids ethyl esters in patients suffering from heart failure |
| EP03739455A EP1474125A1 (en) | 2002-02-12 | 2003-02-05 | The use of omega-3 polyunsaturated acids ethyl esters in patients suffering from heart failure |
| PCT/EP2003/001108 WO2003068216A1 (en) | 2002-02-12 | 2003-02-05 | The use of omega-3 polyunsaturated acids ethyl esters in patients suffering from heart failure |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2002MI000269A ITMI20020269A1 (en) | 2002-02-12 | 2002-02-12 | USE OF OMEGA-3 POLYUNSATURATED ACID ETHYL STERES IN PATIENTS WITH HEART INSUFFICIENCY |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ITMI20020269A0 ITMI20020269A0 (en) | 2002-02-12 |
| ITMI20020269A1 true ITMI20020269A1 (en) | 2003-08-12 |
Family
ID=11449201
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT2002MI000269A ITMI20020269A1 (en) | 2002-02-12 | 2002-02-12 | USE OF OMEGA-3 POLYUNSATURATED ACID ETHYL STERES IN PATIENTS WITH HEART INSUFFICIENCY |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1474125A1 (en) |
| AU (1) | AU2003210210A1 (en) |
| IT (1) | ITMI20020269A1 (en) |
| WO (1) | WO2003068216A1 (en) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9901809D0 (en) | 1999-01-27 | 1999-03-17 | Scarista Limited | Highly purified ethgyl epa and other epa derivatives for psychiatric and neurological disorderes |
| ITMI20022511A1 (en) * | 2002-11-26 | 2004-05-27 | Victorix Assets Ltd | USE OF PHARMACEUTICAL COMPOSITIONS CONTAINING ETHYL ESTERS OF OMEGA-3 POLYUNSATURATED ACIDS IN THE ORDER OF ATRIAL FIBRILLATION. |
| GB0403247D0 (en) | 2004-02-13 | 2004-03-17 | Tillotts Pharma Ag | A pharmaceutical composition |
| ES2277557B1 (en) | 2005-12-21 | 2008-07-01 | Proyecto Empresarial Brudy, S.L. | USE OF DOCOSAHEXAENOIC ACID FOR THE TREATMENT OF OXIDATIVE CELL DAMAGE. |
| PL1962825T3 (en) * | 2005-12-21 | 2014-09-30 | Brudy Tech S L | Use of dha for treating a pathology associated with cellular oxidative damage |
| US20110236476A1 (en) | 2008-09-02 | 2011-09-29 | Amarin Corporation Plc. | Pharmaceutical composition comprising eicosapentaenoic acid and nicotinic acid and methods of using same |
| PT3037089T (en) | 2009-02-10 | 2020-03-04 | Amarin Pharmaceuticals Ie Ltd | Eicosapentaenoic acid ethyl ester for treating hypertriglyceridemia |
| KR102118478B1 (en) * | 2009-03-09 | 2020-06-04 | 바스프 에이에스 | Compositions comprising a fatty acid oil mixture and a surfactant, and methods and uses thereof |
| SG10201605794PA (en) | 2009-04-29 | 2016-09-29 | Amarin Pharmaceuticals Ie Ltd | Stable Pharmaceutical Composition And Methods Of Using Same |
| WO2010127099A2 (en) | 2009-04-29 | 2010-11-04 | Amarin Corporation Plc | Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same |
| CN108096209A (en) | 2009-06-15 | 2018-06-01 | 阿马里纳制药公司 | Triglycerides, composition and method without increasing LDL-C levels are reduced in the object of associated Statins therapy |
| WO2011038122A1 (en) | 2009-09-23 | 2011-03-31 | Amarin Corporation Plc | Pharmaceutical composition comprising omega-3 fatty acid and hydroxy-derivative of a statin and methods of using same |
| US11712429B2 (en) | 2010-11-29 | 2023-08-01 | Amarin Pharmaceuticals Ireland Limited | Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity |
| EP2646013A4 (en) | 2010-11-29 | 2014-03-26 | Amarin Pharma Inc | LOW-ERUCATION COMPOSITION AND METHODS FOR TREATING AND / OR PREVENTING CARDIOVASCULAR DISEASE IN A SUBJECT HAVING FISH ALLERGY / HYPERSENSITIVITY |
| EP2674157A4 (en) | 2011-02-07 | 2014-07-09 | Mochida Pharm Co Ltd | Therapeutic agent for diastolic congestive heart failure |
| US11291643B2 (en) | 2011-11-07 | 2022-04-05 | Amarin Pharmaceuticals Ireland Limited | Methods of treating hypertriglyceridemia |
| EP2775837A4 (en) | 2011-11-07 | 2015-10-28 | Amarin Pharmaceuticals Ie Ltd | Methods of treating hypertriglyceridemia |
| JP6307442B2 (en) | 2012-01-06 | 2018-04-04 | アマリン ファーマシューティカルス アイルランド リミテッド | Compositions and methods for reducing the level of high sensitivity (HS-CRP) in a subject |
| SMT202500326T1 (en) | 2012-06-29 | 2025-11-10 | Amarin Pharmaceuticals Ie Ltd | Eicosapentaenoic acid ethyl ester for use in reducing the risk of non-fatal stroke in a subject on statin therapy |
| US20150265566A1 (en) | 2012-11-06 | 2015-09-24 | Amarin Pharmaceuticals Ireland Limited | Compositions and Methods for Lowering Triglycerides without Raising LDL-C Levels in a Subject on Concomitant Statin Therapy |
| US9814733B2 (en) | 2012-12-31 | 2017-11-14 | A,arin Pharmaceuticals Ireland Limited | Compositions comprising EPA and obeticholic acid and methods of use thereof |
| US20140187633A1 (en) | 2012-12-31 | 2014-07-03 | Amarin Pharmaceuticals Ireland Limited | Methods of treating or preventing nonalcoholic steatohepatitis and/or primary biliary cirrhosis |
| US9452151B2 (en) | 2013-02-06 | 2016-09-27 | Amarin Pharmaceuticals Ireland Limited | Methods of reducing apolipoprotein C-III |
| US9624492B2 (en) | 2013-02-13 | 2017-04-18 | Amarin Pharmaceuticals Ireland Limited | Compositions comprising eicosapentaenoic acid and mipomersen and methods of use thereof |
| US9662307B2 (en) | 2013-02-19 | 2017-05-30 | The Regents Of The University Of Colorado | Compositions comprising eicosapentaenoic acid and a hydroxyl compound and methods of use thereof |
| US9283201B2 (en) | 2013-03-14 | 2016-03-15 | Amarin Pharmaceuticals Ireland Limited | Compositions and methods for treating or preventing obesity in a subject in need thereof |
| US20140271841A1 (en) | 2013-03-15 | 2014-09-18 | Amarin Pharmaceuticals Ireland Limited | Pharmaceutical composition comprising eicosapentaenoic acid and derivatives thereof and a statin |
| US10966968B2 (en) | 2013-06-06 | 2021-04-06 | Amarin Pharmaceuticals Ireland Limited | Co-administration of rosiglitazone and eicosapentaenoic acid or a derivative thereof |
| US20150065572A1 (en) | 2013-09-04 | 2015-03-05 | Amarin Pharmaceuticals Ireland Limited | Methods of treating or preventing prostate cancer |
| US9585859B2 (en) | 2013-10-10 | 2017-03-07 | Amarin Pharmaceuticals Ireland Limited | Compositions and methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy |
| US10561631B2 (en) | 2014-06-11 | 2020-02-18 | Amarin Pharmaceuticals Ireland Limited | Methods of reducing RLP-C |
| WO2015195662A1 (en) | 2014-06-16 | 2015-12-23 | Amarin Pharmaceuticals Ireland Limited | Methods of reducing or preventing oxidation of small dense ldl or membrane polyunsaturated fatty acids |
| US10406130B2 (en) | 2016-03-15 | 2019-09-10 | Amarin Pharmaceuticals Ireland Limited | Methods of reducing or preventing oxidation of small dense LDL or membrane polyunsaturated fatty acids |
| WO2018213663A1 (en) | 2017-05-19 | 2018-11-22 | Amarin Pharmaceuticals Ireland Limited | Compositions and methods for lowering triglycerides in a subject having reduced kidney function |
| US11058661B2 (en) | 2018-03-02 | 2021-07-13 | Amarin Pharmaceuticals Ireland Limited | Compositions and methods for lowering triglycerides in a subject on concomitant statin therapy and having hsCRP levels of at least about 2 mg/L |
| EP3700518A4 (en) | 2018-09-24 | 2020-12-16 | Amarin Pharmaceuticals Ireland Limited | METHODS FOR REDUCING THE RISK OF CARDIOVASCULAR EVENTS IN A SUBJECT |
| CN114980973A (en) | 2019-11-12 | 2022-08-30 | 阿马里纳药物爱尔兰有限公司 | Method for reducing the risk of cardiovascular events in a subject with atrial fibrillation and/or atrial flutter |
| EP4326244A4 (en) | 2021-04-21 | 2025-03-19 | Amarin Pharmaceuticals Ireland Limited | Methods of reducing the risk of heart failure |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1308613B1 (en) * | 1999-02-17 | 2002-01-09 | Pharmacia & Upjohn Spa | ESSENTIAL FATTY ACIDS IN THE PREVENTION OF CARDIOVASCULAR EVENTS. |
| ATE305810T1 (en) * | 2000-05-22 | 2005-10-15 | Pro Aparts Investimentos E Con | PHARMACEUTICAL COMPOSITION CONTAINING FATTY ACID WHICH IS AT LEAST 80 Wt. CONTAINS EPA AND DHA |
| ITMI20010129A1 (en) * | 2001-01-25 | 2002-07-25 | Pharmacia & Upjohn Spa | ESSENTIAL FATTY ACIDS IN THE THERAPY OF HEART INSUFFICIENCY AND HEART FAILURE |
-
2002
- 2002-02-12 IT IT2002MI000269A patent/ITMI20020269A1/en unknown
-
2003
- 2003-02-05 EP EP03739455A patent/EP1474125A1/en not_active Withdrawn
- 2003-02-05 AU AU2003210210A patent/AU2003210210A1/en not_active Abandoned
- 2003-02-05 WO PCT/EP2003/001108 patent/WO2003068216A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003210210A1 (en) | 2003-09-04 |
| WO2003068216A1 (en) | 2003-08-21 |
| ITMI20020269A0 (en) | 2002-02-12 |
| EP1474125A1 (en) | 2004-11-10 |
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