ITFI20040173A1 - Profarmaci attivati da dna polimerasi dipendenti da rna - Google Patents

Profarmaci attivati da dna polimerasi dipendenti da rna

Info

Publication number: ITFI20040173A1
Authority: IT; Italy
Prior art keywords: rna; dependent polymerase; activated dna; dna drugs; drugs
Prior art date: 2004-08-03

Application number

IT000173A

Other languages

English (en)

Inventor

Ivano Bertini

Massimo Calamante

Claudio Luchinat

Alessandro Quattrone

Original Assignee

Protera S R L

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-08-03

Filing date

2004-08-03

Publication date

2004-11-03

2004-08-03 Application filed by Protera S R L filed Critical Protera S R L

2004-08-03 Priority to IT000173A priority Critical patent/ITFI20040173A1/it

2004-11-03 Publication of ITFI20040173A1 publication Critical patent/ITFI20040173A1/it

2005-08-02 Priority to CNA2005800260597A priority patent/CN101031308A/zh

2005-08-02 Priority to AU2005268775A priority patent/AU2005268775A1/en

2005-08-02 Priority to US11/659,269 priority patent/US8110676B2/en

2005-08-02 Priority to EP05779043A priority patent/EP1778254A2/en

2005-08-02 Priority to JP2007524340A priority patent/JP2008509110A/ja

2005-08-02 Priority to PCT/EP2005/053765 priority patent/WO2006013203A2/en

2005-08-02 Priority to CA002575520A priority patent/CA2575520A1/en

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7115—Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
- A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7125—Nucleic acids or oligonucleotides having modified internucleoside linkage, i.e. other than 3'-5' phosphodiesters
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Virology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Enzymes And Modification Thereof (AREA)
Medicinal Preparation (AREA)

IT000173A 2004-08-03 2004-08-03 Profarmaci attivati da dna polimerasi dipendenti da rna ITFI20040173A1 (it)

Priority Applications (8)

Application Number	Priority Date	Filing Date	Title
IT000173A ITFI20040173A1 (it)	2004-08-03	2004-08-03	Profarmaci attivati da dna polimerasi dipendenti da rna
CNA2005800260597A CN101031308A (zh)	2004-08-03	2005-08-02	由rna依赖性dna聚合酶活化的药物前体
AU2005268775A AU2005268775A1 (en)	2004-08-03	2005-08-02	Prodrugs activated by RNA-dependent DNA-polymerases
US11/659,269 US8110676B2 (en)	2004-08-03	2005-08-02	Prodrugs activated by RNA-dependent DNA-polymerases
EP05779043A EP1778254A2 (en)	2004-08-03	2005-08-02	Prodrugs activated by rna-dependent dna-polymerases
JP2007524340A JP2008509110A (ja)	2004-08-03	2005-08-02	Ｒｎａ依存性ｄｎａポリメラーゼで活性化されるプロドラッグ
PCT/EP2005/053765 WO2006013203A2 (en)	2004-08-03	2005-08-02	Prodrugs activated by rna-dependent dna-polymerases
CA002575520A CA2575520A1 (en)	2004-08-03	2005-08-02	Prodrugs activated by rna-dependent dna-polymerases

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT000173A ITFI20040173A1 (it)	2004-08-03	2004-08-03	Profarmaci attivati da dna polimerasi dipendenti da rna

Publications (1)

Publication Number	Publication Date
ITFI20040173A1 true ITFI20040173A1 (it)	2004-11-03

Family

ID=35589591

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT000173A ITFI20040173A1 (it)	2004-08-03	2004-08-03	Profarmaci attivati da dna polimerasi dipendenti da rna

Country Status (8)

Country	Link
US (1)	US8110676B2 (it)
EP (1)	EP1778254A2 (it)
JP (1)	JP2008509110A (it)
CN (1)	CN101031308A (it)
AU (1)	AU2005268775A1 (it)
CA (1)	CA2575520A1 (it)
IT (1)	ITFI20040173A1 (it)
WO (1)	WO2006013203A2 (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0625283D0 (en)	2006-12-19	2007-01-24	Cyclacel Ltd	Combination
US7998967B2 (en) *	2008-03-03	2011-08-16	Tosk, Incorporated	Methotrexate adjuvants to reduce toxicity and methods for using the same
EP3578563B1 (en)	2011-12-22	2021-04-14	Geron Corporation	Guanine analogs as telomerase substrates and telomere length affectors
CN103665043B (zh)	2012-08-30	2017-11-10	江苏豪森药业集团有限公司	一种替诺福韦前药及其在医药上的应用
US20190100553A1 (en) *	2016-04-12	2019-04-04	The Board Of Trustees Of The Leland Stanford Junior University	Direct activity assays and compositions for nucleotide pool sanitizing enzymes
US20250002524A1 (en) *	2021-07-30	2025-01-02	CureVac SE	Cap analogs having an acyclic linker to the guanine derivative nucleobase

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR880000094B1 (ko) *	1984-12-07	1988-02-23	보령제약 주식회사	뉴클레오시드 유도체의 제조방법
JPH0920792A (ja) *	1995-07-11	1997-01-21	Soyaku Gijutsu Kenkyusho:Kk	ヌクレオチドダイマー
AU2003217863B9 (en)	2002-02-28	2009-10-29	Biota Scientific Management Pty Ltd	Nucleotide mimics and their prodrugs
EP1601789A4 (en) *	2003-01-16	2007-10-31	Idera Pharmaceuticals Inc	MODULATION OF IMMUNOSTIMULATORY PROPERTIES OF OLIGONUCLEOTIDE-BASED COMPOUNDS USING MODIFIED IMMUNOSTIMULATORY DINUCLEOTIDES

2004
- 2004-08-03 IT IT000173A patent/ITFI20040173A1/it unknown
2005
- 2005-08-02 JP JP2007524340A patent/JP2008509110A/ja active Pending
- 2005-08-02 US US11/659,269 patent/US8110676B2/en not_active Expired - Fee Related
- 2005-08-02 WO PCT/EP2005/053765 patent/WO2006013203A2/en active Application Filing
- 2005-08-02 EP EP05779043A patent/EP1778254A2/en not_active Withdrawn
- 2005-08-02 AU AU2005268775A patent/AU2005268775A1/en not_active Abandoned
- 2005-08-02 CA CA002575520A patent/CA2575520A1/en not_active Abandoned
- 2005-08-02 CN CNA2005800260597A patent/CN101031308A/zh active Pending

Also Published As

Publication number	Publication date
US20080300215A1 (en)	2008-12-04
EP1778254A2 (en)	2007-05-02
US8110676B2 (en)	2012-02-07
CA2575520A1 (en)	2006-02-09
JP2008509110A (ja)	2008-03-27
CN101031308A (zh)	2007-09-05
AU2005268775A1 (en)	2006-02-09
WO2006013203A3 (en)	2006-07-27
WO2006013203A2 (en)	2006-02-09

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EP1863864A4 (en)	2009-10-28	RETICULABLE BIOPOLYMER
EP1743019A4 (en)	2009-09-23	MICROFLUIDIC CHEMOSTAT
NO20053892D0 (no)	2005-08-19	Virale polymeraseinhibitorer
BRPI0819193A2 (pt)	2017-05-23	uso de oligonucleotídeos com bases modificadas na hibridização de ácidos nucleicos.
DE602005007508D1 (de)	2008-07-24	Funktioneller zuckerersatz
MA28639B1 (fr)	2007-06-01	Vaccins
EP1731525A4 (en)	2010-01-20	NUCLEOTIDE DERIVATIVES AND DNA CHIP
EP1771442A4 (en)	2009-12-30	INHIBITORS OF VIRAL POLYMERASE
DE602005026188D1 (de)	2011-03-17	Medikamentenspender
MA29108B1 (fr)	2007-12-03	Macrolides
MA28885B1 (fr)	2007-09-03	vaccins
EP1871347A4 (en)	2012-10-31	PHARMACEUTICAL COMPOSITION
DE502005008168D1 (de)	2009-11-05	Pipette
DE602005027253D1 (de)	2011-05-12	Herbizidresistenz verleihende gene
EP1756129A4 (en)	2010-05-26	NEW INTERCALATORS INTO THE DNA
DE602004031713D1 (de)	2011-04-21	Optischer Biochip
DK1765844T3 (da)	2014-09-01	Purin-nukleotidderivater
EP1718149A4 (en)	2010-06-09	SYSTEM IMMUNE ACTIVATION PROCEDURE USING NON-CPG NUCLEIC ACIDS
EP1718335A4 (en)	2010-11-10	drug conjugates
ITFI20040173A1 (it)	2004-11-03	Profarmaci attivati da dna polimerasi dipendenti da rna
DE502005000305D1 (de)	2007-02-22	Photobioreaktor
ITMI20041447A1 (it)	2004-10-20	Composizione farmaceutica comprendente gabapentina
DE602005017643D1 (de)	2009-12-24	Medikamentenverdunster