ITFI20030070A1 - Formulazioni topiche stabilizzate contenenti ketoprofene - Google Patents
Formulazioni topiche stabilizzate contenenti ketoprofeneInfo
- Publication number
- ITFI20030070A1 ITFI20030070A1 IT000070A ITFI20030070A ITFI20030070A1 IT FI20030070 A1 ITFI20030070 A1 IT FI20030070A1 IT 000070 A IT000070 A IT 000070A IT FI20030070 A ITFI20030070 A IT FI20030070A IT FI20030070 A1 ITFI20030070 A1 IT FI20030070A1
- Authority
- IT
- Italy
- Prior art keywords
- formulations containing
- ketoprofene
- topical formulations
- skin
- stabilized topical
- Prior art date
Links
- DKYWVDODHFEZIM-UHFFFAOYSA-N ketoprofen Chemical compound OC(=O)C(C)C1=CC=CC(C(=O)C=2C=CC=CC=2)=C1 DKYWVDODHFEZIM-UHFFFAOYSA-N 0.000 title abstract 2
- 229960000991 ketoprofen Drugs 0.000 title abstract 2
- 239000012049 topical pharmaceutical composition Substances 0.000 title 1
- NLZUEZXRPGMBCV-UHFFFAOYSA-N Butylhydroxytoluene Chemical compound CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1 NLZUEZXRPGMBCV-UHFFFAOYSA-N 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- ANJLMAHUPYCFQY-UHFFFAOYSA-N 4-phenyl-1h-benzimidazole-2-sulfonic acid Chemical compound C=12NC(S(=O)(=O)O)=NC2=CC=CC=1C1=CC=CC=C1 ANJLMAHUPYCFQY-UHFFFAOYSA-N 0.000 abstract 1
- YBGZDTIWKVFICR-JLHYYAGUSA-N Octyl 4-methoxycinnamic acid Chemical compound CCCCC(CC)COC(=O)\C=C\C1=CC=C(OC)C=C1 YBGZDTIWKVFICR-JLHYYAGUSA-N 0.000 abstract 1
- 239000004904 UV filter Substances 0.000 abstract 1
- 239000003963 antioxidant agent Substances 0.000 abstract 1
- 230000003078 antioxidant effect Effects 0.000 abstract 1
- 229960002783 dexketoprofen Drugs 0.000 abstract 1
- DKYWVDODHFEZIM-NSHDSACASA-N dexketoprofen Chemical compound OC(=O)[C@@H](C)C1=CC=CC(C(=O)C=2C=CC=CC=2)=C1 DKYWVDODHFEZIM-NSHDSACASA-N 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 230000000622 irritating effect Effects 0.000 abstract 1
- 229960001679 octinoxate Drugs 0.000 abstract 1
- 230000035515 penetration Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Priority Applications (20)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000070A ITFI20030070A1 (it) | 2003-03-18 | 2003-03-18 | Formulazioni topiche stabilizzate contenenti ketoprofene |
| TW093106275A TWI327912B (en) | 2003-03-18 | 2004-03-10 | Stabilized topical formulations containing ketoprofen |
| MYPI20040902A MY140025A (en) | 2003-03-18 | 2004-03-15 | Stabilized topical formulations containing ketoprofen |
| DE602004018291T DE602004018291D1 (de) | 2003-03-18 | 2004-03-17 | Photostabilisierte topische formulierungen von ketoprofen mit zwei uv-filtern |
| EP04721199A EP1613300B1 (en) | 2003-03-18 | 2004-03-17 | Photostabilized topical formulations of ketoprofen containing two uv filters |
| SI200431048T SI1613300T1 (sl) | 2003-03-18 | 2004-03-17 | Fotostabilizirane topiäśne formulacije ketoprofena, vsebujoäśe dva uv filtra |
| DK04721199T DK1613300T3 (da) | 2003-03-18 | 2004-03-17 | Fotostabiliserede topiske ketoprofen-formuleringer indeholdende to UV-filtre |
| PCT/EP2004/050317 WO2004082580A2 (en) | 2003-03-18 | 2004-03-17 | Photostabilized topical formulations of ketoprofen containing two uv filters |
| KR1020057017267A KR20060008869A (ko) | 2003-03-18 | 2004-03-17 | 2개의 ｕｖ 필터를 포함하는 케토프로펜의 광안정화된 국부제형물 |
| ES04721199T ES2321837T3 (es) | 2003-03-18 | 2004-03-17 | Formulaciones topicas fotoestabilizadas de ketoprofeno conteniendo dos filtros uv. |
| AT04721199T ATE416763T1 (de) | 2003-03-18 | 2004-03-17 | Photostabilisierte topische formulierungen von ketoprofen mit zwei uv-filtern |
| CNA2004800067627A CN1767824A (zh) | 2003-03-18 | 2004-03-17 | 含有酮洛芬(ketoprofen)的稳定局部配方 |
| PL04721199T PL1613300T3 (pl) | 2003-03-18 | 2004-03-17 | Fotostabilizowane preparaty ketoprofenu do stosowania miejscowego, zawierające dwa filtry UV |
| RU2005132004/15A RU2340335C2 (ru) | 2003-03-18 | 2004-03-17 | Стабилизированные композиции для местного применения, содержащие кетопрофен |
| UAA200509210A UA82871C2 (en) | 2003-03-18 | 2004-03-17 | Photostabilized topical formulations of ketoprofen |
| PT04721199T PT1613300E (pt) | 2003-03-18 | 2004-03-17 | Formulações tópicas fotoestabilizadas de cetoprofeno que contêm dois filtros uv |
| MXPA05009902A MXPA05009902A (es) | 2003-03-18 | 2004-03-17 | Formulaciones topicas foto-estabilizadas de ketoprofeno que contienen dos filtros uv. |
| MA28524A MA27669A1 (fr) | 2003-03-18 | 2005-09-30 | Formulations topiques stabilisees contenant du ketoprofene |
| ZA200508153A ZA200508153B (en) | 2003-03-18 | 2005-10-10 | Photostabilized topical formulations of ketoprofen containing two UV filters |
| CY20091100257T CY1108869T1 (el) | 2003-03-18 | 2009-03-06 | Φωτοσταθεροποιημενα τοπικα σκευασματα κετοπροφαινης που περιεχουν δυο φιλτρα uv |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000070A ITFI20030070A1 (it) | 2003-03-18 | 2003-03-18 | Formulazioni topiche stabilizzate contenenti ketoprofene |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ITFI20030070A1 true ITFI20030070A1 (it) | 2004-09-19 |
Family
ID=33017958
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT000070A ITFI20030070A1 (it) | 2003-03-18 | 2003-03-18 | Formulazioni topiche stabilizzate contenenti ketoprofene |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP1613300B1 (it) |
| KR (1) | KR20060008869A (it) |
| CN (1) | CN1767824A (it) |
| AT (1) | ATE416763T1 (it) |
| CY (1) | CY1108869T1 (it) |
| DE (1) | DE602004018291D1 (it) |
| DK (1) | DK1613300T3 (it) |
| ES (1) | ES2321837T3 (it) |
| IT (1) | ITFI20030070A1 (it) |
| MA (1) | MA27669A1 (it) |
| MX (1) | MXPA05009902A (it) |
| MY (1) | MY140025A (it) |
| PL (1) | PL1613300T3 (it) |
| PT (1) | PT1613300E (it) |
| RU (1) | RU2340335C2 (it) |
| SI (1) | SI1613300T1 (it) |
| TW (1) | TWI327912B (it) |
| UA (1) | UA82871C2 (it) |
| WO (1) | WO2004082580A2 (it) |
| ZA (1) | ZA200508153B (it) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2089007A2 (en) * | 2006-10-27 | 2009-08-19 | Noven Pharmaceuticals, INC. | Transdermal delivery of ketoprofen polar derivatives |
| EP2153815A1 (en) | 2008-08-05 | 2010-02-17 | Isdin S.A. | Use of urea containing compositions |
| EP2153814A1 (en) | 2008-08-05 | 2010-02-17 | Isdin S.A. | Use of compositions comprising urea |
| RU2404760C1 (ru) * | 2009-04-07 | 2010-11-27 | Государственное образовательное учреждение высшего профессионального образования "Пятигорская государственная фармацевтическая академия Федерального агентства по здравоохранению и социальному развитию" | Композиция - лекарственная форма нестероидного противовоспалительного средства кетопрофена для наружного применения |
| JP5123333B2 (ja) | 2010-01-26 | 2013-01-23 | 株式会社 資生堂 | 油中水型乳化日焼け止め化粧料 |
| CN102068405A (zh) * | 2010-12-16 | 2011-05-25 | 天津工业大学 | 一种酮洛芬凝胶及其制备方法 |
| WO2013022410A2 (en) | 2011-08-08 | 2013-02-14 | Mahmut Bilgic | Production method for effervescent formulations comprising dexketoprofen |
| US8822537B2 (en) * | 2012-09-27 | 2014-09-02 | Achelios Therapeutics, Inc. | Topical ketoprofen composition |
| CN103804184B (zh) * | 2014-02-14 | 2016-02-03 | 南京科胜医药科技有限公司 | 精氨酸酮洛芬的晶型及制备方法 |
| RU2667465C2 (ru) * | 2015-10-28 | 2018-09-19 | Закрытое Акционерное Общество "Фармфирма "Сотекс" | Фармацевтическая композиция для наружного применения, содержащая соль декскетопрофена, и способ ее получения |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60155111A (ja) * | 1983-10-20 | 1985-08-15 | Hisamitsu Pharmaceut Co Inc | 安定なケトプロフェン含有外用経皮製剤 |
| AU8927191A (en) * | 1990-10-05 | 1992-04-28 | Analgesic Associates | Prevention or treatment of sunburn using the s(+) isomer of flurbiprofen |
| KR930701977A (ko) * | 1990-10-05 | 1993-09-08 | 원본미기재 | 케토프로펜의 s(＋) 이성질체를 이용한 일조화상(日照火傷)의 예방 및 치료 |
| US5185373A (en) * | 1991-08-13 | 1993-02-09 | American Home Products Corporation | Inhibition of thermal degradation of ibuprofen |
| DE4444238A1 (de) * | 1994-12-13 | 1996-06-20 | Beiersdorf Ag | Kosmetische oder dermatologische Wirkstoffkombinationen aus Zimtsäurederivaten und Flavonglycosiden |
| AUPN814496A0 (en) * | 1996-02-19 | 1996-03-14 | Monash University | Dermal penetration enhancer |
| FR2804024B1 (fr) * | 2000-01-21 | 2002-09-13 | Menarini France | Nouvelles compositions pharmaceutiques a action anti- inflammatoire et leur procede de preparation |
| AU784779B2 (en) * | 2000-03-17 | 2006-06-15 | Hisamitsu Pharmaceutical Co., Inc. | Ultraviolet-shielding adhesive preparation |
-
2003
- 2003-03-18 IT IT000070A patent/ITFI20030070A1/it unknown
-
2004
- 2004-03-10 TW TW093106275A patent/TWI327912B/zh active
- 2004-03-15 MY MYPI20040902A patent/MY140025A/en unknown
- 2004-03-17 MX MXPA05009902A patent/MXPA05009902A/es active IP Right Grant
- 2004-03-17 RU RU2005132004/15A patent/RU2340335C2/ru not_active IP Right Cessation
- 2004-03-17 SI SI200431048T patent/SI1613300T1/sl unknown
- 2004-03-17 UA UAA200509210A patent/UA82871C2/uk unknown
- 2004-03-17 PL PL04721199T patent/PL1613300T3/pl unknown
- 2004-03-17 EP EP04721199A patent/EP1613300B1/en not_active Expired - Lifetime
- 2004-03-17 KR KR1020057017267A patent/KR20060008869A/ko not_active Ceased
- 2004-03-17 PT PT04721199T patent/PT1613300E/pt unknown
- 2004-03-17 DK DK04721199T patent/DK1613300T3/da active
- 2004-03-17 AT AT04721199T patent/ATE416763T1/de not_active IP Right Cessation
- 2004-03-17 CN CNA2004800067627A patent/CN1767824A/zh active Pending
- 2004-03-17 DE DE602004018291T patent/DE602004018291D1/de not_active Expired - Lifetime
- 2004-03-17 ES ES04721199T patent/ES2321837T3/es not_active Expired - Lifetime
- 2004-03-17 WO PCT/EP2004/050317 patent/WO2004082580A2/en active Search and Examination
-
2005
- 2005-09-30 MA MA28524A patent/MA27669A1/fr unknown
- 2005-10-10 ZA ZA200508153A patent/ZA200508153B/en unknown
-
2009
- 2009-03-06 CY CY20091100257T patent/CY1108869T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1613300A2 (en) | 2006-01-11 |
| RU2005132004A (ru) | 2006-02-27 |
| WO2004082580A2 (en) | 2004-09-30 |
| MXPA05009902A (es) | 2006-03-21 |
| PT1613300E (pt) | 2009-03-27 |
| ATE416763T1 (de) | 2008-12-15 |
| TWI327912B (en) | 2010-08-01 |
| DE602004018291D1 (de) | 2009-01-22 |
| PL1613300T3 (pl) | 2009-05-29 |
| WO2004082580A3 (en) | 2005-01-27 |
| DK1613300T3 (da) | 2009-03-09 |
| MA27669A1 (fr) | 2005-12-01 |
| CY1108869T1 (el) | 2014-07-02 |
| UA82871C2 (en) | 2008-05-26 |
| CN1767824A (zh) | 2006-05-03 |
| TW200509897A (en) | 2005-03-16 |
| SI1613300T1 (sl) | 2009-06-30 |
| ZA200508153B (en) | 2007-10-31 |
| KR20060008869A (ko) | 2006-01-27 |
| MY140025A (en) | 2009-11-30 |
| ES2321837T3 (es) | 2009-06-12 |
| EP1613300B1 (en) | 2008-12-10 |
| RU2340335C2 (ru) | 2008-12-10 |
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