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IT8321084A0 - Penem derivati, loro preparazione e composizioni che li contengono. - Google Patents

Penem derivati, loro preparazione e composizioni che li contengono.

Info

Publication number
IT8321084A0
IT8321084A0 IT8321084A IT2108483A IT8321084A0 IT 8321084 A0 IT8321084 A0 IT 8321084A0 IT 8321084 A IT8321084 A IT 8321084A IT 2108483 A IT2108483 A IT 2108483A IT 8321084 A0 IT8321084 A0 IT 8321084A0
Authority
IT
Italy
Prior art keywords
compositions
contain
preparation
penem derivatives
penem
Prior art date
Application number
IT8321084A
Other languages
English (en)
Other versions
IT1164226B (it
IT8321084A1 (it
Inventor
Tetsuo Miyadera
Yukio Sugimura
Toshihiko Hashimoto
Teruo Tanaka
Kimio Iino
Tomoyuki Shibata
Shinichi Sugawara
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of IT8321084A0 publication Critical patent/IT8321084A0/it
Publication of IT8321084A1 publication Critical patent/IT8321084A1/it
Application granted granted Critical
Publication of IT1164226B publication Critical patent/IT1164226B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/12Oxygen or sulfur atoms
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IT21084/83A 1982-05-14 1983-05-13 Penem derivati,loro preparazione e composizioni che li contengono IT1164226B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57081067A JPS58198486A (ja) 1982-05-14 1982-05-14 ペネムまたはカルバペネム−3−カルボン酸誘導体およびその製法

Publications (3)

Publication Number Publication Date
IT8321084A0 true IT8321084A0 (it) 1983-05-13
IT8321084A1 IT8321084A1 (it) 1984-11-13
IT1164226B IT1164226B (it) 1987-04-08

Family

ID=13736043

Family Applications (1)

Application Number Title Priority Date Filing Date
IT21084/83A IT1164226B (it) 1982-05-14 1983-05-13 Penem derivati,loro preparazione e composizioni che li contengono

Country Status (8)

Country Link
US (1) US4613595A (it)
JP (1) JPS58198486A (it)
CH (1) CH659072A5 (it)
DE (1) DE3317742A1 (it)
ES (2) ES8407053A1 (it)
FR (1) FR2526798B1 (it)
GB (1) GB2121792B (it)
IT (1) IT1164226B (it)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5916892A (ja) * 1982-07-19 1984-01-28 Sankyo Co Ltd カルバペネム−3−カルボン酸誘導体およびその製法
US4772597A (en) * 1983-10-14 1988-09-20 Pfizer Inc. 2-azacycloalkylthiopenem derivatives
CA1339860C (en) * 1985-06-17 1998-05-12 Tsunehiko Soga Derivatives of penem
US4751297A (en) * 1987-03-20 1988-06-14 Pfizer Inc. Method for preparation of azetidinone-1-oxoacetate by oxidation of the corresponding 2-hydroxyacetate
EP0597821A1 (en) * 1988-04-01 1994-05-18 Sankyo Company Limited 2-(Heterocyclylthio)carbapenem derivatives their preparation and their use as antibiotics
US5242914A (en) * 1988-04-01 1993-09-07 Sankyo Company, Limited 2-(heterocyclylthio) carbapenem derivatives, their preparation and their use as antibiotics
JP2783683B2 (ja) * 1992-12-21 1998-08-06 ジョン グン ダン コーポレーション 2−(2−置換されたピロリジン−4−イル)チオ−カバペネム誘導体
WO2023235456A1 (en) * 2022-06-01 2023-12-07 The Johns Hopkins University Penem antibacterials against mycobacterial pathogens and d,d- and l,d transpeptidases

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4168314A (en) * 1977-11-17 1979-09-18 Merck & Co., Inc. 6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid
EP0003960B1 (de) * 1978-02-02 1983-06-29 Ciba-Geigy Ag 6-Substituierte Thia-Azaverbindungen, ihre Herstellung und diese enthaltende pharmazeutische Präparate
DE2961882D1 (en) * 1978-08-25 1982-03-04 Beecham Group Plc Beta-lactam anti-bacterials, compositions containing them and a process for their preparation
JPS55153789A (en) * 1979-04-11 1980-11-29 Sankyo Co Ltd Penem-3-carboxylic acid derivative and its preparation
EP0082133A3 (en) * 1979-04-19 1983-07-20 Merck & Co. Inc. A process for preparing intermediates useful for preparing 2-substituted-6-substituted-1-carbadethiapen-2-em-3-carboxylic acids
US4386030A (en) * 1979-12-31 1983-05-31 Merck & Co., Inc. Process for preparing 6-(1'-hydroxyethyl)-2-substituted-pen-2-em-3-carboxylic acid
DE3176517D1 (en) * 1980-04-24 1987-12-17 Beecham Group Plc Beta-lactam compounds, their preparation and use
GB2083462B (en) * 1980-08-16 1984-05-02 Beecham Group Ltd 2-thiopenem derivatives
JPS57176988A (en) * 1981-04-09 1982-10-30 Sankyo Co Ltd Penam-3-carboxylic acid derivative and its preparation
EP0070204B1 (en) * 1981-07-15 1987-11-19 Sumitomo Pharmaceuticals Company, Limited Carboxylic beta-lactam compounds and the preparation thereof
US4435412A (en) * 1982-11-29 1984-03-06 Schering Corporation 5R,6S,8R-2-(1-Methyl-2-imidazolylmethylthio)-6-(1-hydroxyethyl)penem-3-carboxylic acid

Also Published As

Publication number Publication date
IT1164226B (it) 1987-04-08
ES522389A0 (es) 1984-08-16
GB2121792B (en) 1986-01-08
DE3317742A1 (de) 1983-11-17
ES8504815A1 (es) 1985-05-01
JPS58198486A (ja) 1983-11-18
FR2526798B1 (fr) 1985-10-04
ES8407053A1 (es) 1984-08-16
GB8313399D0 (en) 1983-06-22
FR2526798A1 (fr) 1983-11-18
GB2121792A (en) 1984-01-04
ES528491A0 (es) 1985-05-01
CH659072A5 (de) 1986-12-31
JPH0318638B2 (it) 1991-03-13
IT8321084A1 (it) 1984-11-13
US4613595A (en) 1986-09-23
DE3317742C2 (it) 1991-08-29

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