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IT8319935A0 - N-/8alfa-ergolinil/-n',n'-dietilure e sostituite in posizione 1 e processo per la produzione delle stesse. - Google Patents

N-/8alfa-ergolinil/-n',n'-dietilure e sostituite in posizione 1 e processo per la produzione delle stesse.

Info

Publication number
IT8319935A0
IT8319935A0 IT8319935A IT1993583A IT8319935A0 IT 8319935 A0 IT8319935 A0 IT 8319935A0 IT 8319935 A IT8319935 A IT 8319935A IT 1993583 A IT1993583 A IT 1993583A IT 8319935 A0 IT8319935 A0 IT 8319935A0
Authority
IT
Italy
Prior art keywords
ergolinil
diethylure
8alfa
substituted
same production
Prior art date
Application number
IT8319935A
Other languages
English (en)
Other versions
IT1161209B (it
Inventor
Antonin Cerny
Jiri Krepelka
Karel Rezabek
Miroslav Seda
Original Assignee
Spofa Vereinigte Pharma Werke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spofa Vereinigte Pharma Werke filed Critical Spofa Vereinigte Pharma Werke
Publication of IT8319935A0 publication Critical patent/IT8319935A0/it
Application granted granted Critical
Publication of IT1161209B publication Critical patent/IT1161209B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT19935/83A 1982-03-12 1983-03-07 N-/8alfa-ergolini/-n',n'-dietilure e sostituite in posizione 1 e processo per la produzione delle stesse IT1161209B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS821734A CS231214B1 (en) 1982-03-12 1982-03-12 Processing method of 1-substituted n+l8alpha-ergoline+p-n,diethyl urea

Publications (2)

Publication Number Publication Date
IT8319935A0 true IT8319935A0 (it) 1983-03-07
IT1161209B IT1161209B (it) 1987-03-18

Family

ID=5352449

Family Applications (1)

Application Number Title Priority Date Filing Date
IT19935/83A IT1161209B (it) 1982-03-12 1983-03-07 N-/8alfa-ergolini/-n',n'-dietilure e sostituite in posizione 1 e processo per la produzione delle stesse

Country Status (15)

Country Link
JP (1) JPS58180484A (it)
AT (1) AT383349B (it)
AU (1) AU555961B2 (it)
BE (1) BE896122A (it)
CA (1) CA1203531A (it)
CH (1) CH652125A5 (it)
CS (1) CS231214B1 (it)
DE (1) DE3308719A1 (it)
DK (1) DK84683A (it)
FI (1) FI830754L (it)
FR (1) FR2523131B1 (it)
GB (1) GB2116548B (it)
IT (1) IT1161209B (it)
NL (1) NL8300829A (it)
SE (1) SE452321B (it)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3309493A1 (de) * 1983-03-14 1984-09-20 Schering AG, 1000 Berlin und 4709 Bergkamen Neue ergolin-derivate, verfahren zu ihrer herstellung sowie verwendung als arzneimittel
EP0208417A3 (en) * 1985-06-12 1989-09-06 SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu Use of 1-(8-alpha-ergolinyl)-3,3-diethyl urea derivatives in the treatment of endometritis
DE3522894A1 (de) * 1985-06-24 1987-01-02 Schering Ag Verwendung von tergurid als geriatrikum
FR2584720B1 (fr) * 1985-07-11 1987-10-02 Rhone Poulenc Sante Procede de preparation de derives n-methyles de l'ergoline
DE3620293A1 (de) * 1986-06-16 1987-12-17 Schering Ag 1-und/oder 2-substituierte ergolinderivate
DE3623503A1 (de) * 1986-07-09 1988-01-21 Schering Ag 1-aryl-ergolinyl-harnstoffderivate, verfahren zu deren herstellung sowie die verwendung dieser verbindungen als arzneimittel
DE10212564B4 (de) * 2002-03-12 2007-04-19 Neurobiotec Gmbh 1-Allyl-ergotalkaloid-Derivate und ihre Verwendung zur Prophylaxe und Therapie von Migräne
CA2834882C (en) * 2010-11-11 2018-03-27 Sinoxa Pharma Gmbh Lisuride, terguride and derivatives thereof for use in the prophylaxis and/or treatment of fibrotic changes
CA2974117A1 (en) 2015-01-20 2016-07-28 Xoc Pharmaceuticals, Inc. Ergoline compounds and uses thereof
BR112017015510A2 (pt) 2015-01-20 2018-01-30 Xoc Pharmaceuticals Inc composto de fórmula estrutural (i), método de tratamento e/ou prevenção, método de agonização do receptor d2 em um indivíduo, método de antagonização do receptor d3 em um indivíduo, método de agonização do receptor 5-ht1d em um indivíduo, método de agonização do receptor 5-ht1a em um indivíduo, método de agonização seletiva do receptor 5-ht1d em vez do receptor 5-ht1b em um indivíduo, método de agonização seletiva do re-ceptor 5-ht2c em vez do receptor 5-ht2a ou 5-ht2b em um indivíduo, método de agonização do receptor 5-ht2c em um indivíduo, método de fornecimento de atividade antagonista funcional no receptor 5-ht2b ou receptor 5-ht7, e, método de fornecimento de atividade antagonista funcional nos receptores adrenérgicos em um indivíduo
MX2019014272A (es) 2017-06-01 2020-12-11 Xoc Pharmaceuticals Inc Compuestos policiclicos y usos de los mismos.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH344731A (de) * 1956-05-18 1960-02-29 Sandoz Ag Verfahren zur Herstellung von neuen, am Indolstickstoff alkylierten Derivaten der Lysergsäure-Reihe
AT231082B (de) * 1960-10-12 1964-01-10 Sandoz Ag Verfahren zur Herstellung von neuen Harnstoff-Derivaten
DE3063869D1 (en) * 1979-06-13 1983-07-28 Schering Ag (ergolin-yl)-n', n'-diethyl urea derivatives, their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
BE896122A (fr) 1983-07-01
CS231214B1 (en) 1984-10-15
FI830754L (fi) 1983-09-13
IT1161209B (it) 1987-03-18
SE452321B (sv) 1987-11-23
GB2116548A (en) 1983-09-28
NL8300829A (nl) 1983-10-03
AU1216783A (en) 1983-09-15
JPS58180484A (ja) 1983-10-21
SE8301257D0 (sv) 1983-03-08
AU555961B2 (en) 1986-10-16
CH652125A5 (de) 1985-10-31
ATA72783A (de) 1986-11-15
SE8301257L (sv) 1983-09-13
FR2523131A1 (fr) 1983-09-16
DK84683D0 (da) 1983-02-24
CA1203531A (en) 1986-04-22
DE3308719A1 (de) 1983-09-22
GB2116548B (en) 1985-03-20
AT383349B (de) 1987-06-25
DK84683A (da) 1983-09-13
GB8305735D0 (en) 1983-04-07
FI830754A0 (fi) 1983-03-07
FR2523131B1 (fr) 1987-08-28

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