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IT202000023311A1 - EX VIVO PERFUSION SYSTEM OF AN ORGAN AND RELATED METHOD OF CONTROLLING THE PRESSURE AND FLOW OF THE PERFUSION FLUID OF THE EX VIVO PERFUSION SYSTEM OF AN ORGAN - Google Patents

EX VIVO PERFUSION SYSTEM OF AN ORGAN AND RELATED METHOD OF CONTROLLING THE PRESSURE AND FLOW OF THE PERFUSION FLUID OF THE EX VIVO PERFUSION SYSTEM OF AN ORGAN

Info

Publication number
IT202000023311A1
IT202000023311A1 IT102020000023311A IT202000023311A IT202000023311A1 IT 202000023311 A1 IT202000023311 A1 IT 202000023311A1 IT 102020000023311 A IT102020000023311 A IT 102020000023311A IT 202000023311 A IT202000023311 A IT 202000023311A IT 202000023311 A1 IT202000023311 A1 IT 202000023311A1
Authority
IT
Italy
Prior art keywords
organ
perfusion
vivo
perfusion system
pump
Prior art date
Application number
IT102020000023311A
Other languages
Italian (it)
Inventor
Mauro Atti
Original Assignee
Aferetica S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aferetica S R L filed Critical Aferetica S R L
Priority to IT102020000023311A priority Critical patent/IT202000023311A1/en
Publication of IT202000023311A1 publication Critical patent/IT202000023311A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/14—Mechanical aspects of preservation; Apparatus or containers therefor
    • A01N1/142—Apparatus
    • A01N1/143—Apparatus for organ perfusion

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Description

- una porzione di supporto 30, la quale ? configurata andamento sinusoidale con pulsatilit? impressa dal rotore dalla quarta pompa 58. Ad esempio, la quarta pompa 58 ? una pompa peristaltica. - a support portion 30, which ? configured sinusoidal trend with pulsatility? impressed by the rotor from the fourth pump 58. For example, the fourth pump 58 ? a peristaltic pump.

Successivamente, qualora sia prevista la purificazione Subsequently, if purification is foreseen

Claims (10)

RIVENDICAZIONI 1. Sistema (1) di perfusione ex vivo di un organo (4) comprendente:1. System (1) for ex vivo perfusion of an organ (4) comprising: un serbatoio (16) configurato per contenere un liquido di perfusione (5),a reservoir (16) configured to contain a perfusion liquid (5), primi mezzi di connessione (34) per detto organo; un primo circuito di perfusione (45; 56) configurato per collegare detto serbatoio (16) con detti primi mezzi di connessione (34) per detto organo, detto primo circuito di perfusione (45; 56) comprendendo un primo sistema di pompe (47) configurato per: first connection means (34) for said member; a first perfusion circuit (45; 56) configured to connect said reservoir (16) with said first connection means (34) for said organ, said first perfusion circuit (45; 56) comprising a first pump system (47) configured for: a detta almeno una prima pompa (49) ed essendo disposta in parallelo rispetto a detta almeno una prima pompa (49), l almeno una seconda pompa (50) comprendendo un secondo rotore, il quale ? sfasato rispetto all almeno un primo rotore dell almeno una prima pompa (49) di un angolo di sfasamento (?) in modo tale da ruotare in modo asincrono rispetto al primo rotore nel primo verso di rotazione. to said at least one first pump (49) and being arranged in parallel with respect to said at least one first pump (49), the at least one second pump (50) comprising a second rotor, which is phase shifted with respect to the at least one first rotor of the at least one first pump (49) by a phase angle (?) such that it rotates asynchronously with respect to the first rotor in the first direction of rotation. eAnd direzionare detto liquido di perfusione (5) verso detti primi mezzi di connessione (34) mediante detto primo sistema di pompe (47),directing said perfusion liquid (5) towards said first connection means (34) by means of said first pump system (47), il metodo di controllo ESSENDO CARATTERIZZATO DAL FATTO the control method BEING CHARACTERIZED BY THE FACT DI comprendere la fase di impostare e mantenere una pluralit? di parametri (pi, p OF understand the phase of setting up and maintaining a plurality? of parameters (pi, p sensori di temperatura (12).temperature sensors (12). 10. Metodo di controllo secondo la rivendicazione 8 o 9, in cui detta pluralit? di parametri (pi, pj) comprende 10. Control method according to claim 8 or 9, wherein said plurality? of parameters (pi, pj) includes
IT102020000023311A 2020-10-02 2020-10-02 EX VIVO PERFUSION SYSTEM OF AN ORGAN AND RELATED METHOD OF CONTROLLING THE PRESSURE AND FLOW OF THE PERFUSION FLUID OF THE EX VIVO PERFUSION SYSTEM OF AN ORGAN IT202000023311A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IT102020000023311A IT202000023311A1 (en) 2020-10-02 2020-10-02 EX VIVO PERFUSION SYSTEM OF AN ORGAN AND RELATED METHOD OF CONTROLLING THE PRESSURE AND FLOW OF THE PERFUSION FLUID OF THE EX VIVO PERFUSION SYSTEM OF AN ORGAN

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT102020000023311A IT202000023311A1 (en) 2020-10-02 2020-10-02 EX VIVO PERFUSION SYSTEM OF AN ORGAN AND RELATED METHOD OF CONTROLLING THE PRESSURE AND FLOW OF THE PERFUSION FLUID OF THE EX VIVO PERFUSION SYSTEM OF AN ORGAN

Publications (1)

Publication Number Publication Date
IT202000023311A1 true IT202000023311A1 (en) 2022-04-02

Family

ID=74068346

Family Applications (1)

Application Number Title Priority Date Filing Date
IT102020000023311A IT202000023311A1 (en) 2020-10-02 2020-10-02 EX VIVO PERFUSION SYSTEM OF AN ORGAN AND RELATED METHOD OF CONTROLLING THE PRESSURE AND FLOW OF THE PERFUSION FLUID OF THE EX VIVO PERFUSION SYSTEM OF AN ORGAN

Country Status (1)

Country Link
IT (1) IT202000023311A1 (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140017666A1 (en) * 2012-07-10 2014-01-16 Lifeline Scientific, Inc. Filtration in organ perfusion apparatus
US20150342177A1 (en) * 2014-06-02 2015-12-03 Transmedics, Inc Ex vivo organ care system
CN105660604B (en) * 2016-02-04 2019-03-15 杭州莱普晟医疗科技有限公司 An isolated liver perfusion system and an isolated liver perfusion method
EP3459351A1 (en) * 2016-05-20 2019-03-27 SCREEN Holdings Co., Ltd. Perfusion apparatus for liver for transplantation, and liver isolation method and liver transplantation method using said apparatus
CN209234766U (en) * 2018-09-30 2019-08-13 南京国科医工科技发展有限公司 In vitro liver room temperature oxygen carrying machine perfusion system

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140017666A1 (en) * 2012-07-10 2014-01-16 Lifeline Scientific, Inc. Filtration in organ perfusion apparatus
US20150342177A1 (en) * 2014-06-02 2015-12-03 Transmedics, Inc Ex vivo organ care system
CN105660604B (en) * 2016-02-04 2019-03-15 杭州莱普晟医疗科技有限公司 An isolated liver perfusion system and an isolated liver perfusion method
EP3459351A1 (en) * 2016-05-20 2019-03-27 SCREEN Holdings Co., Ltd. Perfusion apparatus for liver for transplantation, and liver isolation method and liver transplantation method using said apparatus
CN209234766U (en) * 2018-09-30 2019-08-13 南京国科医工科技发展有限公司 In vitro liver room temperature oxygen carrying machine perfusion system

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ESHMUMINOV DILMURODJON ET AL: "An integrated perfusion machine preserves injured human livers for 1 week", NATURE BIOTECHNOLOGY, vol. 38, no. 2, 13 January 2020 (2020-01-13), pages 189 - 198, XP037293632, ISSN: 1087-0156, DOI: 10.1038/S41587-019-0374-X *

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