IT201900025126A1 - Uso di derivati dell’acido ialuronico nella rigenerazione dei tessuti ossei e cartilaginei - Google Patents

Uso di derivati dell’acido ialuronico nella rigenerazione dei tessuti ossei e cartilaginei

Info

Publication number: IT201900025126A1
Authority: IT; Italy
Prior art keywords: cartilage; regeneration; hyaluronic acid; acid derivatives; bone tissues
Prior art date: 2019-12-20

Application number

IT102019000025126A

Other languages

English (en)

Inventor

Demetrio Manenti

Giuliana Abbiati

Original Assignee

Sildeha Swiss S A

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2019-12-20

Filing date

2019-12-20

Publication date

2021-06-20

2019-12-20 Application filed by Sildeha Swiss S A filed Critical Sildeha Swiss S A

2019-12-20 Priority to IT102019000025126A priority Critical patent/IT201900025126A1/it

2020-12-18 Priority to UAA202202575A priority patent/UA129389C2/uk

2020-12-18 Priority to US17/786,752 priority patent/US20230018851A1/en

2020-12-18 Priority to CA3162397A priority patent/CA3162397A1/en

2020-12-18 Priority to JP2022537401A priority patent/JP2023506953A/ja

2020-12-18 Priority to AU2020410540A priority patent/AU2020410540A1/en

2020-12-18 Priority to BR112022012164A priority patent/BR112022012164A2/pt

2020-12-18 Priority to KR1020227025172A priority patent/KR20220140712A/ko

2020-12-18 Priority to IL294054A priority patent/IL294054A/en

2020-12-18 Priority to PCT/IB2020/062186 priority patent/WO2021124249A1/en

2020-12-18 Priority to EP20830336.2A priority patent/EP4076428A1/en

2020-12-18 Priority to CN202080094283.4A priority patent/CN115135318A/zh

2020-12-18 Priority to MX2022007614A priority patent/MX2022007614A/es

2021-06-20 Publication of IT201900025126A1 publication Critical patent/IT201900025126A1/it

2022-06-24 Priority to ZA2022/07058A priority patent/ZA202207058B/en

2022-07-18 Priority to CONC2022/0010207A priority patent/CO2022010207A2/es

Links

KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical class CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 title 1
210000000988 bone and bone Anatomy 0.000 title 1
210000000845 cartilage Anatomy 0.000 title 1
230000008929 regeneration Effects 0.000 title 1
238000011069 regeneration method Methods 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/20—Polysaccharides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/56—Porous materials, e.g. foams or sponges
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/21—Acids
- A61L2300/214—Amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/02—Materials or treatment for tissue regeneration for reconstruction of bones; weight-bearing implants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/06—Materials or treatment for tissue regeneration for cartilage reconstruction, e.g. meniscus

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Physical Education & Sports Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Dermatology (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Oral & Maxillofacial Surgery (AREA)
Transplantation (AREA)
Dispersion Chemistry (AREA)
Materials For Medical Uses (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

IT102019000025126A 2019-12-20 2019-12-20 Uso di derivati dell’acido ialuronico nella rigenerazione dei tessuti ossei e cartilaginei IT201900025126A1 (it)

Priority Applications (15)

Application Number	Priority Date	Filing Date	Title
IT102019000025126A IT201900025126A1 (it)	2019-12-20	2019-12-20	Uso di derivati dell’acido ialuronico nella rigenerazione dei tessuti ossei e cartilaginei
KR1020227025172A KR20220140712A (ko)	2019-12-20	2020-12-18	뼈 및 연골 조직의 재생에서 히알루론산 유도체의 사용
IL294054A IL294054A (en)	2019-12-20	2020-12-18	Hyaluronic acid derivatives for use in the regeneration of bone and cartilage tissues
CA3162397A CA3162397A1 (en)	2019-12-20	2020-12-18	Use of hyaluronic acid derivatives in the regeneration of bone and cartilage tissues
JP2022537401A JP2023506953A (ja)	2019-12-20	2020-12-18	ヒアルロン酸誘導体の骨及び軟骨組織の再生における使用
AU2020410540A AU2020410540A1 (en)	2019-12-20	2020-12-18	Use of hyaluronic acid derivatives in the regeneration of bone and cartilage tissues
BR112022012164A BR112022012164A2 (pt)	2019-12-20	2020-12-18	Composto de ácido hialurônico e pelo menos um heterociclo derivado de purina e/ou pirimidina, composto para uso, estrutura de suporte implantável e formulação farmacêutica
UAA202202575A UA129389C2 (uk)	2019-12-20	2020-12-18	Використання похідних гіалуронової кислоти для регенерації кісткових і хрящових тканин
US17/786,752 US20230018851A1 (en)	2019-12-20	2020-12-18	Use of hyaluronic acid derivatives in the regeneration of bone and cartilage tissues
PCT/IB2020/062186 WO2021124249A1 (en)	2019-12-20	2020-12-18	Use of hyaluronic acid derivatives in the regeneration of bone and cartilage tissues
EP20830336.2A EP4076428A1 (en)	2019-12-20	2020-12-18	Use of hyaluronic acid derivatives in the regeneration of bone and cartilage tissues
CN202080094283.4A CN115135318A (zh)	2019-12-20	2020-12-18	“透明质酸衍生物在骨和软骨组织的再生中的用途”
MX2022007614A MX2022007614A (es)	2019-12-20	2020-12-18	Uso de derivados de ácido hialurónico en la regeneración de tejidos óseos y cartilaginoso.
ZA2022/07058A ZA202207058B (en)	2019-12-20	2022-06-24	Use of hyaluronic acid derivatives in the regeneration of bone and cartilage tissues
CONC2022/0010207A CO2022010207A2 (es)	2019-12-20	2022-07-18	Uso de derivados del ácido hialurónico en la regeneración de tejidos óseos y cartilaginosos

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT102019000025126A IT201900025126A1 (it)	2019-12-20	2019-12-20	Uso di derivati dell’acido ialuronico nella rigenerazione dei tessuti ossei e cartilaginei

Publications (1)

Publication Number	Publication Date
IT201900025126A1 true IT201900025126A1 (it)	2021-06-20

Family

ID=70295628

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT102019000025126A IT201900025126A1 (it)	2019-12-20	2019-12-20	Uso di derivati dell’acido ialuronico nella rigenerazione dei tessuti ossei e cartilaginei

Country Status (15)

Country	Link
US (1)	US20230018851A1 (it)
EP (1)	EP4076428A1 (it)
JP (1)	JP2023506953A (it)
KR (1)	KR20220140712A (it)
CN (1)	CN115135318A (it)
AU (1)	AU2020410540A1 (it)
BR (1)	BR112022012164A2 (it)
CA (1)	CA3162397A1 (it)
CO (1)	CO2022010207A2 (it)
IL (1)	IL294054A (it)
IT (1)	IT201900025126A1 (it)
MX (1)	MX2022007614A (it)
UA (1)	UA129389C2 (it)
WO (1)	WO2021124249A1 (it)
ZA (1)	ZA202207058B (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT201900025126A1 (it) *	2019-12-20	2021-06-20	Sildeha Swiss S A	Uso di derivati dell’acido ialuronico nella rigenerazione dei tessuti ossei e cartilaginei

Citations (3)

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US6761887B1 (en) *	1998-11-16	2004-07-13	Osiris Therapeutics, Inc.	Alginate layer system for chondrogenic differentiation of human mesenchymal stem cells
EP1525224A1 (en) *	2002-07-26	2005-04-27	Jasper Ltd. Liability Co.	Hyaluronic acid derivatives
EP1525244A1 (en)	2002-07-22	2005-04-27	Basf Corporation	Polyether polyol for foam applications

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WO2000029552A1 (en) *	1998-11-16	2000-05-25	Osiris Therapeutics, Inc.	Alginate layer system for chondrogenic differentiation of human mesenchymal stem cells
BR0116845A (pt) *	2001-01-31	2004-02-25	Pfizer Prod Inc	Derivados éter úteis como inibidores de isozimas pde4
US20060149392A1 (en) *	2004-12-07	2006-07-06	Kuo-Huang Hsieh	Biomaterials for guided tissue regeneration and drug delivery
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KR101706642B1 (ko) *	2015-02-04	2017-02-17	주식회사 엑소스템텍	연골세포로 분화되고 있는 줄기세포로부터 추출된 엑소좀을 포함하는 연골세포 분화 유도 또는 연골조직 재생용 조성물
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2019
- 2019-12-20 IT IT102019000025126A patent/IT201900025126A1/it unknown
2020
- 2020-12-18 EP EP20830336.2A patent/EP4076428A1/en active Pending
- 2020-12-18 CA CA3162397A patent/CA3162397A1/en active Pending
- 2020-12-18 IL IL294054A patent/IL294054A/en unknown
- 2020-12-18 KR KR1020227025172A patent/KR20220140712A/ko active Pending
- 2020-12-18 UA UAA202202575A patent/UA129389C2/uk unknown
- 2020-12-18 MX MX2022007614A patent/MX2022007614A/es unknown
- 2020-12-18 JP JP2022537401A patent/JP2023506953A/ja active Pending
- 2020-12-18 US US17/786,752 patent/US20230018851A1/en active Pending
- 2020-12-18 WO PCT/IB2020/062186 patent/WO2021124249A1/en active Application Filing
- 2020-12-18 CN CN202080094283.4A patent/CN115135318A/zh active Pending
- 2020-12-18 BR BR112022012164A patent/BR112022012164A2/pt unknown
- 2020-12-18 AU AU2020410540A patent/AU2020410540A1/en active Pending
2022
- 2022-06-24 ZA ZA2022/07058A patent/ZA202207058B/en unknown
- 2022-07-18 CO CONC2022/0010207A patent/CO2022010207A2/es unknown

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US6761887B1 (en) *	1998-11-16	2004-07-13	Osiris Therapeutics, Inc.	Alginate layer system for chondrogenic differentiation of human mesenchymal stem cells
EP1525244A1 (en)	2002-07-22	2005-04-27	Basf Corporation	Polyether polyol for foam applications
EP1525224A1 (en) *	2002-07-26	2005-04-27	Jasper Ltd. Liability Co.	Hyaluronic acid derivatives

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Also Published As

Publication number	Publication date
UA129389C2 (uk)	2025-04-09
CN115135318A (zh)	2022-09-30
CA3162397A1 (en)	2021-06-24
MX2022007614A (es)	2022-10-20
ZA202207058B (en)	2023-05-31
AU2020410540A1 (en)	2022-07-21
JP2023506953A (ja)	2023-02-20
CO2022010207A2 (es)	2022-10-21
BR112022012164A2 (pt)	2022-09-13
EP4076428A1 (en)	2022-10-26
KR20220140712A (ko)	2022-10-18
IL294054A (en)	2022-08-01
US20230018851A1 (en)	2023-01-19
WO2021124249A1 (en)	2021-06-24

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EA201592073A1 (ru)	2016-05-31	Фармацевтические композиции, содержащие коллаген и гиалуронат натрия
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BR112018003455A2 (pt)	2018-09-25	composição ou composição farmacêutica e uso da composição
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