IT1403720B1 - METHOD OF DETECTION OF A PROTEOLYTIC ENZYME BY MEANS OF AMPLIFICATION OF A SIGNAL CATALIZED BY GOLD NANOPARTICLES - Google Patents
METHOD OF DETECTION OF A PROTEOLYTIC ENZYME BY MEANS OF AMPLIFICATION OF A SIGNAL CATALIZED BY GOLD NANOPARTICLESInfo
- Publication number
- IT1403720B1 IT1403720B1 ITPD2010A000388A ITPD20100388A IT1403720B1 IT 1403720 B1 IT1403720 B1 IT 1403720B1 IT PD2010A000388 A ITPD2010A000388 A IT PD2010A000388A IT PD20100388 A ITPD20100388 A IT PD20100388A IT 1403720 B1 IT1403720 B1 IT 1403720B1
- Authority
- IT
- Italy
- Prior art keywords
- catalized
- amplification
- detection
- signal
- proteolytic enzyme
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
- C07K17/14—Peptides being immobilised on, or in, an inorganic carrier
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITPD2010A000388A IT1403720B1 (en) | 2010-12-22 | 2010-12-22 | METHOD OF DETECTION OF A PROTEOLYTIC ENZYME BY MEANS OF AMPLIFICATION OF A SIGNAL CATALIZED BY GOLD NANOPARTICLES |
| PCT/EP2011/073585 WO2012085080A1 (en) | 2010-12-22 | 2011-12-21 | Method of detecting a proteolytic enzyme by means of gold nanoparticles- catalyzed amplification of a signal |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITPD2010A000388A IT1403720B1 (en) | 2010-12-22 | 2010-12-22 | METHOD OF DETECTION OF A PROTEOLYTIC ENZYME BY MEANS OF AMPLIFICATION OF A SIGNAL CATALIZED BY GOLD NANOPARTICLES |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ITPD20100388A1 ITPD20100388A1 (en) | 2012-06-23 |
| IT1403720B1 true IT1403720B1 (en) | 2013-10-31 |
Family
ID=43737197
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITPD2010A000388A IT1403720B1 (en) | 2010-12-22 | 2010-12-22 | METHOD OF DETECTION OF A PROTEOLYTIC ENZYME BY MEANS OF AMPLIFICATION OF A SIGNAL CATALIZED BY GOLD NANOPARTICLES |
Country Status (2)
| Country | Link |
|---|---|
| IT (1) | IT1403720B1 (en) |
| WO (1) | WO2012085080A1 (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010101628A2 (en) | 2009-03-02 | 2010-09-10 | Massachusetts Institute Of Technology | Methods and products for in vivo enzyme profiling |
| AU2012229103A1 (en) | 2011-03-15 | 2013-10-31 | Massachusetts Institute Of Technology | Multiplexed detection with isotope-coded reporters |
| ES2828985T3 (en) | 2013-06-07 | 2021-05-28 | Massachusetts Inst Technology | Affinity-based detection of synthetic ligand-encoded biomarkers |
| EP3149484A1 (en) * | 2014-05-30 | 2017-04-05 | IMRA America, Inc. | Gold nanoparticle-based homogeneous colorimetric diagnostic assay for the detection of proteases and protease inhibitors |
| WO2017177115A1 (en) | 2016-04-08 | 2017-10-12 | Massachusetts Institute Of Technology | Methods to specifically profile protease activity at lymph nodes |
| CA3022928A1 (en) | 2016-05-05 | 2017-11-09 | Massachusetts Institute Of Technology | Methods and uses for remotely triggered protease activity measurements |
| CA3059358A1 (en) | 2017-04-07 | 2018-10-11 | Massachusetts Institute Of Technology | Methods to spatially profile protease activity in tissue and sections |
| WO2019173332A1 (en) | 2018-03-05 | 2019-09-12 | Massachusetts Institute Of Technology | Inhalable nanosensors with volatile reporters and uses thereof |
| WO2020068920A2 (en) | 2018-09-25 | 2020-04-02 | Massachusetts Institute Of Technology | Lung protease nanosensors and uses thereof |
| WO2020081635A2 (en) * | 2018-10-16 | 2020-04-23 | Massachusetts Institute Of Technology | Renal clearable nanocatalysts for disease monitoring |
| US11835522B2 (en) | 2019-01-17 | 2023-12-05 | Massachusetts Institute Of Technology | Sensors for detecting and imaging of cancer metastasis |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0608091A2 (en) * | 2005-03-03 | 2009-11-10 | Revance Therapeutics Inc | compositions and processes for topical application and transdermal delivery of an oligopeptide |
| DE102005051978A1 (en) * | 2005-10-31 | 2007-05-10 | Forschungszentrum Borstel Zentrum für Medizin und Biowissenschaften | Method for determining the cleavability of substrates |
| WO2007100392A2 (en) * | 2005-11-30 | 2007-09-07 | Biotium, Inc. | Enzyme substrate comprising a functional dye and associated technology and methods |
-
2010
- 2010-12-22 IT ITPD2010A000388A patent/IT1403720B1/en active
-
2011
- 2011-12-21 WO PCT/EP2011/073585 patent/WO2012085080A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO2012085080A1 (en) | 2012-06-28 |
| ITPD20100388A1 (en) | 2012-06-23 |
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