IT1398782B1 - Peptide monofosforilato isolato derivato dall'alfa-enolasi umana utile per la diagnosi e il trattamento dell'adenocarcinoma pancreatico, anticorpi diretti contro il suddetto peptide monofosforilato e loro usi. - Google Patents

Peptide monofosforilato isolato derivato dall'alfa-enolasi umana utile per la diagnosi e il trattamento dell'adenocarcinoma pancreatico, anticorpi diretti contro il suddetto peptide monofosforilato e loro usi.

Info

Publication number: IT1398782B1
Authority: IT; Italy
Prior art keywords: peptide; monophosphorylate; enolase; suffered; diagnosis
Prior art date: 2009-09-11

Application number

ITTO2009A000697A

Other languages

English (en)

Inventor

Francesco Novelli

Paola Cappello

Barbara Tomaino

Original Assignee

Novelli

Natimab Therapeutics S R L

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2009-09-11

Filing date

2009-09-11

Publication date

2013-03-18

2009-09-11 Application filed by Novelli, Natimab Therapeutics S R L filed Critical Novelli

2009-09-11 Priority to ITTO2009A000697A priority Critical patent/IT1398782B1/it

2010-09-09 Priority to US13/394,350 priority patent/US8895697B2/en

2010-09-09 Priority to ES10763018.8T priority patent/ES2448804T3/es

2010-09-09 Priority to EP10763018.8A priority patent/EP2475685B1/en

2010-09-09 Priority to PCT/IB2010/054069 priority patent/WO2011030302A1/en

2011-03-12 Publication of ITTO20090697A1 publication Critical patent/ITTO20090697A1/it

2013-03-18 Application granted granted Critical

2013-03-18 Publication of IT1398782B1 publication Critical patent/IT1398782B1/it

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y402/00—Carbon-oxygen lyases (4.2)
- C12Y402/01—Hydro-lyases (4.2.1)
- C12Y402/01011—Phosphopyruvate hydratase (4.2.1.11), i.e. enolase
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57438—Specifically defined cancers of liver, pancreas or kidney

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Wood Science & Technology (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Urology & Nephrology (AREA)
Zoology (AREA)
Biochemistry (AREA)
Immunology (AREA)
Biomedical Technology (AREA)
Medicinal Chemistry (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Hematology (AREA)
General Engineering & Computer Science (AREA)
Oncology (AREA)
Analytical Chemistry (AREA)
Pathology (AREA)
General Physics & Mathematics (AREA)
Gastroenterology & Hepatology (AREA)
Physics & Mathematics (AREA)
Hospice & Palliative Care (AREA)
Food Science & Technology (AREA)
Cell Biology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Peptides Or Proteins (AREA)

ITTO2009A000697A 2009-09-11 2009-09-11 Peptide monofosforilato isolato derivato dall'alfa-enolasi umana utile per la diagnosi e il trattamento dell'adenocarcinoma pancreatico, anticorpi diretti contro il suddetto peptide monofosforilato e loro usi. IT1398782B1 (it)

Priority Applications (5)

Application Number	Priority Date	Filing Date	Title
ITTO2009A000697A IT1398782B1 (it)	2009-09-11	2009-09-11	Peptide monofosforilato isolato derivato dall'alfa-enolasi umana utile per la diagnosi e il trattamento dell'adenocarcinoma pancreatico, anticorpi diretti contro il suddetto peptide monofosforilato e loro usi.
US13/394,350 US8895697B2 (en)	2009-09-11	2010-09-09	Isolated monophosphorylated peptide derived from human alpha-enolase useful for diagnosis and treatment of pancreatic adenocarcinoma, antibodies directed against the said monophosphorylated peptide, and uses thereof
ES10763018.8T ES2448804T3 (es)	2009-09-11	2010-09-09	Un péptido monofosforilado aislado derivado de alfa-enolasa humana útil para diagnóstico y tratamiento del adenocarcinoma pancreático, anticuerpos dirigidos contra dicho péptido monofosforilado, y sus usos
EP10763018.8A EP2475685B1 (en)	2009-09-11	2010-09-09	An isolated monophosphorylated peptide derived from human alpha-enolase useful for diagnosis and treatment of pancreatic adenocarcinoma, antibodies directed against the said monophosphorylated peptide, and uses thereof
PCT/IB2010/054069 WO2011030302A1 (en)	2009-09-11	2010-09-09	An isolated monophosphorylated peptide derived from human alpha-enolase useful for diagnosis and treatment of pancreatic adenocarcinoma, antibodies directed against the said monophosphorylated peptide, and uses thereof

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
ITTO2009A000697A IT1398782B1 (it)	2009-09-11	2009-09-11	Peptide monofosforilato isolato derivato dall'alfa-enolasi umana utile per la diagnosi e il trattamento dell'adenocarcinoma pancreatico, anticorpi diretti contro il suddetto peptide monofosforilato e loro usi.

Publications (2)

Publication Number	Publication Date
ITTO20090697A1 ITTO20090697A1 (it)	2011-03-12
IT1398782B1 true IT1398782B1 (it)	2013-03-18

Family

ID=42111811

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ITTO2009A000697A IT1398782B1 (it)	2009-09-11	2009-09-11	Peptide monofosforilato isolato derivato dall'alfa-enolasi umana utile per la diagnosi e il trattamento dell'adenocarcinoma pancreatico, anticorpi diretti contro il suddetto peptide monofosforilato e loro usi.

Country Status (5)

Country	Link
US (1)	US8895697B2 (it)
EP (1)	EP2475685B1 (it)
ES (1)	ES2448804T3 (it)
IT (1)	IT1398782B1 (it)
WO (1)	WO2011030302A1 (it)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN106102835B (zh)	2014-01-13	2020-11-03	博格有限责任公司	烯醇酶1(eno1)组合物及其用途
IT202100024779A1 (it)	2021-09-28	2023-03-28	Univ Degli Studi Di Torino	Vaccino a DNA per l’uso nel trattamento profilattico o terapeutico dell’adenocarcinoma duttale pancreatico

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20040142325A1 (en) *	2001-09-14	2004-07-22	Liat Mintz	Methods and systems for annotating biomolecular sequences
US20040219572A1 (en)	2002-12-17	2004-11-04	Jie Chen	Specific markers for pancreatic cancer
EP2069395B1 (en) *	2006-09-29	2012-01-25	Ribovax Biotechnologies SA	Novel antigens and antibodies associated to pancreatic ductal adenocarcinoma

2009
- 2009-09-11 IT ITTO2009A000697A patent/IT1398782B1/it active
2010
- 2010-09-09 US US13/394,350 patent/US8895697B2/en active Active
- 2010-09-09 WO PCT/IB2010/054069 patent/WO2011030302A1/en active Application Filing
- 2010-09-09 EP EP10763018.8A patent/EP2475685B1/en not_active Not-in-force
- 2010-09-09 ES ES10763018.8T patent/ES2448804T3/es active Active

Also Published As

Publication number	Publication date
US8895697B2 (en)	2014-11-25
WO2011030302A1 (en)	2011-03-17
US20120164146A1 (en)	2012-06-28
ITTO20090697A1 (it)	2011-03-12
ES2448804T3 (es)	2014-03-17
EP2475685A1 (en)	2012-07-18
EP2475685B1 (en)	2013-11-27

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