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IT1317927B1 - Uso della pentraxina lunga ptx3 per la preparazione di un medicamentoper il trattamento di patologie autoimmuni. - Google Patents

Uso della pentraxina lunga ptx3 per la preparazione di un medicamentoper il trattamento di patologie autoimmuni.

Info

Publication number
IT1317927B1
IT1317927B1 IT2000RM000571A ITRM20000571A IT1317927B1 IT 1317927 B1 IT1317927 B1 IT 1317927B1 IT 2000RM000571 A IT2000RM000571 A IT 2000RM000571A IT RM20000571 A ITRM20000571 A IT RM20000571A IT 1317927 B1 IT1317927 B1 IT 1317927B1
Authority
IT
Italy
Prior art keywords
preparation
medicine
treatment
autoimmune pathologies
long pentraxin
Prior art date
Application number
IT2000RM000571A
Other languages
English (en)
Inventor
Alberto Mantovani
Barbara Bottazzi
Giuseppe Peri
Angelo Manfredi
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of ITRM20000571A0 publication Critical patent/ITRM20000571A0/it
Priority to IT2000RM000571A priority Critical patent/IT1317927B1/it
Priority to PL01365291A priority patent/PL365291A1/xx
Priority to EP01983771A priority patent/EP1370279B1/en
Priority to PCT/IT2001/000530 priority patent/WO2002036151A2/en
Priority to CA002427533A priority patent/CA2427533A1/en
Priority to AT01983771T priority patent/ATE303819T1/de
Priority to MXPA03003805A priority patent/MXPA03003805A/es
Priority to AU1518902A priority patent/AU1518902A/xx
Priority to DK01983771T priority patent/DK1370279T3/da
Priority to HU0401593A priority patent/HUP0401593A2/hu
Priority to CNB018182984A priority patent/CN1326563C/zh
Priority to JP2002538961A priority patent/JP4105542B2/ja
Priority to US10/415,413 priority patent/US20040029803A1/en
Priority to BR0115050-2A priority patent/BR0115050A/pt
Priority to ES01983771T priority patent/ES2248401T3/es
Priority to CZ20031043A priority patent/CZ297242B6/cs
Priority to AU2002215189A priority patent/AU2002215189B2/en
Priority to KR1020037005650A priority patent/KR100812805B1/ko
Priority to DE60113304T priority patent/DE60113304T2/de
Priority to SK533-2003A priority patent/SK5332003A3/sk
Publication of ITRM20000571A1 publication Critical patent/ITRM20000571A1/it
Application granted granted Critical
Publication of IT1317927B1 publication Critical patent/IT1317927B1/it
Priority to HK05104020A priority patent/HK1071291A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Reproductive Health (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT2000RM000571A 2000-11-03 2000-11-03 Uso della pentraxina lunga ptx3 per la preparazione di un medicamentoper il trattamento di patologie autoimmuni. IT1317927B1 (it)

Priority Applications (21)

Application Number Priority Date Filing Date Title
IT2000RM000571A IT1317927B1 (it) 2000-11-03 2000-11-03 Uso della pentraxina lunga ptx3 per la preparazione di un medicamentoper il trattamento di patologie autoimmuni.
CNB018182984A CN1326563C (zh) 2000-11-03 2001-10-18 长的正五聚蛋白ptx3在制备预防和治疗自身免疫性疾病的药物中的用途
US10/415,413 US20040029803A1 (en) 2000-11-03 2001-10-18 Use of the long pentraxin ptx3 for the preparation of medicament for the prevention and cure of autoimmune pathologies
PCT/IT2001/000530 WO2002036151A2 (en) 2000-11-03 2001-10-18 Use of the long pentraxin ptx3 for the preparation of medicament for the prevention and cure of autoimmune pathologies
CA002427533A CA2427533A1 (en) 2000-11-03 2001-10-18 Use of the long pentraxin ptx3 for the preparation of medicament for the prevention and cure of autoimmune pathologies
AT01983771T ATE303819T1 (de) 2000-11-03 2001-10-18 Verwendung von langem pentraxin ptx3 zur herstellung eines arzneimittels zur verhütung und heilung von autoimmunkrankheiten
MXPA03003805A MXPA03003805A (es) 2000-11-03 2001-10-18 Uso de pentraxina de cadena larga ptx3 para la preparacion de un farmaco para la prevencion y cura de patologias autoinmunitarias.
AU1518902A AU1518902A (en) 2000-11-03 2001-10-18 Use of the long pentraxin ptx3 for the preparation of medicament for the prevention and cure of autoimmune pathologies
DK01983771T DK1370279T3 (da) 2000-11-03 2001-10-18 Anvendelse af det lange pentraxin PTX3 til fremstilling af et lægemiddel til forebyggelse og helbredelse af autoimmuni patologier
HU0401593A HUP0401593A2 (hu) 2000-11-03 2001-10-18 A PTX3 hosszú pentraxin alkalmazása gyógyhatású készítmény előállítására autoimmun betegségek megelőzésére és kezelésére
PL01365291A PL365291A1 (en) 2000-11-03 2001-10-18 Use of the long pentraxin ptx3 for the preparation of medicament for the prevention and cure of autoimmune pathologies
JP2002538961A JP4105542B2 (ja) 2000-11-03 2001-10-18 自己免疫疾患の予防および治療用薬物の調製のための長いペントラキシンｐｔｘ３の使用
EP01983771A EP1370279B1 (en) 2000-11-03 2001-10-18 Use of the long pentraxin ptx3 for the preparation of medicament for the prevention and cure of autoimmune pathologies
BR0115050-2A BR0115050A (pt) 2000-11-03 2001-10-18 Uso da pentraxina longa ptx3 para a preparação de um medicamento para a prevenção e a cura de patologias da auto-imunização
ES01983771T ES2248401T3 (es) 2000-11-03 2001-10-18 Uso de la pentraxina ptx3 larga para la preparacion de un medicamento para la prevencion y tratamiento de patologias autoinmunes.
CZ20031043A CZ297242B6 (cs) 2000-11-03 2001-10-18 Pouzití pentraxinu s dlouhým retezcem PTX3 k príprave léciva pro prevenci a lécbu autoimunních patologických projevu
AU2002215189A AU2002215189B2 (en) 2000-11-03 2001-10-18 Use of the long pentraxin PTX3 for the preparation of medicament for the prevention and cure of autoimmune pathologies
KR1020037005650A KR100812805B1 (ko) 2000-11-03 2001-10-18 자가면역 질환의 예방 및 치료용 약제의 제조를 위한 긴펜트락신 ｐｔｘ3의 용도
DE60113304T DE60113304T2 (de) 2000-11-03 2001-10-18 Verwendung von langem pentraxin ptx3 zur herstellung eines arzneimittels zur verhütung und heilung von autoimmunkrankheiten
SK533-2003A SK5332003A3 (en) 2000-11-03 2001-10-18 Use of the long pentraxin PTX3 for the preparation of medicament for the prevention and cure of autoimmune pathologies
HK05104020A HK1071291A1 (en) 2000-11-03 2005-05-13 User of the long pentraxin ptx3 for the preparation of medicament for the prevention and cure of autoimmune pathologies

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2000RM000571A IT1317927B1 (it) 2000-11-03 2000-11-03 Uso della pentraxina lunga ptx3 per la preparazione di un medicamentoper il trattamento di patologie autoimmuni.

Publications (3)

Publication Number Publication Date
ITRM20000571A0 ITRM20000571A0 (it) 2000-11-03
ITRM20000571A1 ITRM20000571A1 (it) 2002-05-03
IT1317927B1 true IT1317927B1 (it) 2003-07-15

Family

ID=11454977

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2000RM000571A IT1317927B1 (it) 2000-11-03 2000-11-03 Uso della pentraxina lunga ptx3 per la preparazione di un medicamentoper il trattamento di patologie autoimmuni.

Country Status (20)

Country Link
US (1) US20040029803A1 (it)
EP (1) EP1370279B1 (it)
JP (1) JP4105542B2 (it)
KR (1) KR100812805B1 (it)
CN (1) CN1326563C (it)
AT (1) ATE303819T1 (it)
AU (2) AU2002215189B2 (it)
BR (1) BR0115050A (it)
CA (1) CA2427533A1 (it)
CZ (1) CZ297242B6 (it)
DE (1) DE60113304T2 (it)
DK (1) DK1370279T3 (it)
ES (1) ES2248401T3 (it)
HK (1) HK1071291A1 (it)
HU (1) HUP0401593A2 (it)
IT (1) IT1317927B1 (it)
MX (1) MXPA03003805A (it)
PL (1) PL365291A1 (it)
SK (1) SK5332003A3 (it)
WO (1) WO2002036151A2 (it)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1298487B1 (it) * 1997-12-19 2000-01-10 Sigma Tau Ind Farmaceuti Composizioni farmaceutiche comprendenti pentraxina lunga ptx3 per la terapia di patologie di tipo infettivo, infiammatorio o tumorale,
ITRM20020109A1 (it) * 2002-02-28 2003-08-28 Sigma Tau Ind Farmaceuti Derivati funzionali della pentraxina lunga ptx3 per preparare un vaccino autologo per la cura dei tumori.
EP1599226B1 (en) * 2003-02-21 2012-09-19 Medvet Science Pty. Ltd. A method of diagnosis and treatment
ITRM20030595A1 (it) * 2003-12-23 2005-06-24 Sigma Tau Ind Farmaceuti Uso della ptx3 o di un suo derivato funzionale da sola o in associazione con tsg6 per il trattamento di patologie degenarative dell'osso o della cartilagine e per il trattamento della infertilita' femminile.
ITRM20030596A1 (it) * 2003-12-23 2005-06-24 Sigma Tau Ind Farmaceuti Uso di inibitori della pentraxina lunga ptx3, per la preparazione di un medicamento per la prevenzione e cura di patologie che rispondono all'inibizione dell'attivita' biologica di detta ptx3.
ITRM20040489A1 (it) 2004-10-08 2005-01-08 Sigma Tau Ind Farmaceuti Pentraxina lunga ptx3 deglicosilata o desialidata.
EP1832295A1 (en) * 2006-03-10 2007-09-12 Tecnogen S.P.A. Use of PTX3 for the treatment of viral diseases
CN101437535B (zh) 2006-05-02 2013-01-30 希格马托制药工业公司 胸腺素α1单独地或与PTX3或更昔洛韦联合在治疗巨细胞病毒感染中的用途
KR101305515B1 (ko) 2011-06-10 2013-09-06 경북대학교 산학협력단 펜트락신 3 단백질의 파킨슨 질환 진단 용도
WO2013191280A1 (ja) * 2012-06-22 2013-12-27 国立大学法人 東京大学 全身性炎症反応症候群の治療又は予防剤
CN105903001A (zh) * 2016-05-09 2016-08-31 中国科学院海洋研究所 一种鱼类穿透素的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1298487B1 (it) * 1997-12-19 2000-01-10 Sigma Tau Ind Farmaceuti Composizioni farmaceutiche comprendenti pentraxina lunga ptx3 per la terapia di patologie di tipo infettivo, infiammatorio o tumorale,
US6013217A (en) * 1997-12-22 2000-01-11 Dow Corning Corporation Method for extruding thermoplastic resins

Also Published As

Publication number Publication date
PL365291A1 (en) 2004-12-27
CZ297242B6 (cs) 2006-10-11
CA2427533A1 (en) 2002-05-10
CZ20031043A3 (cs) 2003-09-17
DE60113304D1 (de) 2005-10-13
HK1071291A1 (en) 2005-07-15
JP2004512372A (ja) 2004-04-22
JP4105542B2 (ja) 2008-06-25
KR20030060918A (ko) 2003-07-16
CN1326563C (zh) 2007-07-18
EP1370279B1 (en) 2005-09-07
KR100812805B1 (ko) 2008-03-12
US20040029803A1 (en) 2004-02-12
CN1561226A (zh) 2005-01-05
MXPA03003805A (es) 2004-04-20
ITRM20000571A0 (it) 2000-11-03
ATE303819T1 (de) 2005-09-15
AU1518902A (en) 2002-05-15
ITRM20000571A1 (it) 2002-05-03
ES2248401T3 (es) 2006-03-16
DK1370279T3 (da) 2006-01-23
DE60113304T2 (de) 2006-06-08
BR0115050A (pt) 2003-09-30
WO2002036151A2 (en) 2002-05-10
SK5332003A3 (en) 2003-12-02
HUP0401593A2 (hu) 2004-12-28
AU2002215189B2 (en) 2006-08-03
EP1370279A2 (en) 2003-12-17
WO2002036151A3 (en) 2003-10-16

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