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IT1317841B1 - Derivati del 3,9-diazabiciclo(3.3.1)nonano ad attivita' analgesica. - Google Patents

Derivati del 3,9-diazabiciclo(3.3.1)nonano ad attivita' analgesica.

Info

Publication number
IT1317841B1
IT1317841B1 IT2000MI000293A ITMI20000293A IT1317841B1 IT 1317841 B1 IT1317841 B1 IT 1317841B1 IT 2000MI000293 A IT2000MI000293 A IT 2000MI000293A IT MI20000293 A ITMI20000293 A IT MI20000293A IT 1317841 B1 IT1317841 B1 IT 1317841B1
Authority
IT
Italy
Prior art keywords
nonanal
analgesic activity
diazabicycle
derivatives
diazabicycle derivatives
Prior art date
Application number
IT2000MI000293A
Other languages
English (en)
Inventor
Giorgio Cignarella
Gerard Aime Pinna
Original Assignee
Univ Degli Studi Milano
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Degli Studi Milano filed Critical Univ Degli Studi Milano
Priority to IT2000MI000293A priority Critical patent/IT1317841B1/it
Publication of ITMI20000293A0 publication Critical patent/ITMI20000293A0/it
Priority to PCT/EP2001/001541 priority patent/WO2001060823A1/en
Priority to EP01909740A priority patent/EP1259511A1/en
Priority to AU2001237377A priority patent/AU2001237377A1/en
Priority to US10/221,209 priority patent/US20030195217A1/en
Publication of ITMI20000293A1 publication Critical patent/ITMI20000293A1/it
Application granted granted Critical
Publication of IT1317841B1 publication Critical patent/IT1317841B1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IT2000MI000293A 2000-02-18 2000-02-18 Derivati del 3,9-diazabiciclo(3.3.1)nonano ad attivita' analgesica. IT1317841B1 (it)

Priority Applications (5)

Application Number Priority Date Filing Date Title
IT2000MI000293A IT1317841B1 (it) 2000-02-18 2000-02-18 Derivati del 3,9-diazabiciclo(3.3.1)nonano ad attivita' analgesica.
PCT/EP2001/001541 WO2001060823A1 (en) 2000-02-18 2001-02-13 3,9-diazabicyclo[3.3.1]nonane derivatives with analgesic activity
EP01909740A EP1259511A1 (en) 2000-02-18 2001-02-13 3,9-diazabicyclo 3.3.1]nonane derivatives with analgesic activity
AU2001237377A AU2001237377A1 (en) 2000-02-18 2001-02-13 3,9-diazabicyclo(3.3.1)nonane derivatives with analgesic activity
US10/221,209 US20030195217A1 (en) 2000-02-18 2001-02-13 3,9-Diazabicyclo[3.3.1]nonane derivatives with analgesic activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2000MI000293A IT1317841B1 (it) 2000-02-18 2000-02-18 Derivati del 3,9-diazabiciclo(3.3.1)nonano ad attivita' analgesica.

Publications (3)

Publication Number Publication Date
ITMI20000293A0 ITMI20000293A0 (it) 2000-02-18
ITMI20000293A1 ITMI20000293A1 (it) 2001-08-18
IT1317841B1 true IT1317841B1 (it) 2003-07-15

Family

ID=11444089

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2000MI000293A IT1317841B1 (it) 2000-02-18 2000-02-18 Derivati del 3,9-diazabiciclo(3.3.1)nonano ad attivita' analgesica.

Country Status (5)

Country Link
US (1) US20030195217A1 (it)
EP (1) EP1259511A1 (it)
AU (1) AU2001237377A1 (it)
IT (1) IT1317841B1 (it)
WO (1) WO2001060823A1 (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4588444B2 (ja) * 2002-07-26 2010-12-01 ニューロサーチ、アクティーゼルスカブ ジアザビシクロノナン及び−デカン誘導体並びにこれをオピオイドレセプターリガンドとして使用する方法
EP1678176A1 (en) * 2003-10-13 2006-07-12 Actelion Pharmaceuticals Ltd. Diazabicyclononene derivatives and their use as renin inhibitors
IT1390850B1 (it) * 2008-07-31 2011-10-19 Neuroscienze Pharmaness S C A R L Microemulsioni
IT1390848B1 (it) * 2008-07-31 2011-10-19 Neuroscienze Pharmaness S C A R L Composti farmaceutici
IT1395452B1 (it) * 2009-02-25 2012-09-21 Neuroscienze Pharmaness S C A Rl Microemulsioni
EP2149370A1 (en) 2008-07-31 2010-02-03 Neuroscienze Pharmaness S.C. A R.L. Diazabicyclic compounds and microemulsions thereof
IT1396951B1 (it) 2009-12-18 2012-12-20 Neuroscienze Pharmaness S C A R L Composti farmaceutici

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5187166A (en) * 1990-07-31 1993-02-16 Nisshin Flour Milling Co., Ltd. Azabicyclo derivatives and their use as antiemetics
US5344831A (en) * 1992-01-31 1994-09-06 Nisshin Flour Milling Co., Ltd. Diazabicyclo derivatives
IT1274018B (it) * 1994-02-23 1997-07-14 Riace Ets Derivati del 3,8-diazabiciclo(3.2.1.)ottano ad attivita' analgesica

Also Published As

Publication number Publication date
AU2001237377A1 (en) 2001-08-27
WO2001060823A1 (en) 2001-08-23
ITMI20000293A1 (it) 2001-08-18
ITMI20000293A0 (it) 2000-02-18
US20030195217A1 (en) 2003-10-16
EP1259511A1 (en) 2002-11-27

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