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IT1303688B1 - Derivati aromatici e relativi complessi di fe(iii) atti all'usocome agenti normalizzanti del livello di ferro nell'organismo. - Google Patents

Derivati aromatici e relativi complessi di fe(iii) atti all'usocome agenti normalizzanti del livello di ferro nell'organismo.

Info

Publication number
IT1303688B1
IT1303688B1 IT1998MI002350A ITMI982350A IT1303688B1 IT 1303688 B1 IT1303688 B1 IT 1303688B1 IT 1998MI002350 A IT1998MI002350 A IT 1998MI002350A IT MI982350 A ITMI982350 A IT MI982350A IT 1303688 B1 IT1303688 B1 IT 1303688B1
Authority
IT
Italy
Prior art keywords
acts
iii
complex
iron level
aromatic derivatives
Prior art date
Application number
IT1998MI002350A
Other languages
English (en)
Inventor
Napoli Guido Di
Original Assignee
Medidom Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to IT1998MI002350A priority Critical patent/IT1303688B1/it
Application filed by Medidom Lab filed Critical Medidom Lab
Priority to IL14281399A priority patent/IL142813A0/xx
Priority to PL347940A priority patent/PL198826B1/pl
Priority to CA002348380A priority patent/CA2348380C/en
Priority to EP99971418A priority patent/EP1124814B1/en
Priority to US09/830,800 priority patent/US6455578B1/en
Priority to PCT/EP1999/008222 priority patent/WO2000026205A1/en
Priority to AT99971418T priority patent/ATE229947T1/de
Priority to SI9930227T priority patent/SI1124814T1/xx
Priority to DE69904635T priority patent/DE69904635T2/de
Priority to SK556-2001A priority patent/SK286308B6/sk
Priority to AU11573/00A priority patent/AU756726B2/en
Priority to JP2000579593A priority patent/JP2002528539A/ja
Priority to CZ20011461A priority patent/CZ299542B6/cs
Priority to ES99971418T priority patent/ES2189537T3/es
Priority to BR9914863-3A priority patent/BR9914863A/pt
Priority to DK99971418T priority patent/DK1124814T3/da
Priority to ARP990105492A priority patent/AR021037A1/es
Publication of ITMI982350A1 publication Critical patent/ITMI982350A1/it
Application granted granted Critical
Publication of IT1303688B1 publication Critical patent/IT1303688B1/it
Priority to IL142813A priority patent/IL142813A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/04Chelating agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT1998MI002350A 1998-11-02 1998-11-02 Derivati aromatici e relativi complessi di fe(iii) atti all'usocome agenti normalizzanti del livello di ferro nell'organismo. IT1303688B1 (it)

Priority Applications (19)

Application Number Priority Date Filing Date Title
IT1998MI002350A IT1303688B1 (it) 1998-11-02 1998-11-02 Derivati aromatici e relativi complessi di fe(iii) atti all'usocome agenti normalizzanti del livello di ferro nell'organismo.
JP2000579593A JP2002528539A (ja) 1998-11-02 1999-10-29 鉄濃度の規格化剤として使用する芳香族誘導体とその鉄錯体
CA002348380A CA2348380C (en) 1998-11-02 1999-10-29 Aromatic derivatives and iron complexes thereof for the use as normalising agents of the iron level
EP99971418A EP1124814B1 (en) 1998-11-02 1999-10-29 Aromatic derivatives and iron complexes thereof for the use as normalising agents of the iron level
US09/830,800 US6455578B1 (en) 1998-11-02 1999-10-29 Aromatic derivatives and iron complexes thereof for the use as normalizing agents of the iron level
PCT/EP1999/008222 WO2000026205A1 (en) 1998-11-02 1999-10-29 Aromatic derivatives and iron complexes thereof for the use as normalising agents of the iron level
AT99971418T ATE229947T1 (de) 1998-11-02 1999-10-29 Derivate von aromaten und deren eisen komplexe zur verwendung als regulierungsmittel des eisenspiegels
SI9930227T SI1124814T1 (en) 1998-11-02 1999-10-29 Aromatic derivatives and iron complexes thereof for the use as normalising agents of the iron level
IL14281399A IL142813A0 (en) 1998-11-02 1999-10-29 Aromatic derivatives and iron complexes thereof for use as normalising agents of the iron level
SK556-2001A SK286308B6 (en) 1998-11-02 1999-10-29 Aromatic derivatives and iron complexes thereof for use as normalising agents of iron level
AU11573/00A AU756726B2 (en) 1998-11-02 1999-10-29 Aromatic derivatives and iron complexes thereof for the use as normalising agents of the iron level
PL347940A PL198826B1 (pl) 1998-11-02 1999-10-29 Pochodne aromatyczne, ich kompleksy z żelazem, kompozycje farmaceutyczne zawierające pochodne aromatyczne lub ich kompleksy z żelazem, zastosowanie pochodnych aromatycznych i ich kompleksów z żelazem
CZ20011461A CZ299542B6 (cs) 1998-11-02 1999-10-29 Aromatické deriváty a jejich komplexy se železem jako cinidla pro normalizaci hladiny železa
ES99971418T ES2189537T3 (es) 1998-11-02 1999-10-29 Derivados aromaticos y complejos de hierro de los mismos para su uso como agentes normalizantes del nivel de hierro.
BR9914863-3A BR9914863A (pt) 1998-11-02 1999-10-29 Derivados aromáticos e complexos de ferro dos mesmos para uso como agentes de normalização do nìvel de ferro
DK99971418T DK1124814T3 (da) 1998-11-02 1999-10-29 Aromatiske derivater og jernkomplekser deraf til anvendelse som normaliseringsmidler for jernspejlet
ARP990105492A AR021037A1 (es) 1998-11-02 1999-10-29 Derivados aromaticos y sus relativos complejos de hierro aptos para el uso como agentes normalizantes del nivel de hierro en el organismo
DE69904635T DE69904635T2 (de) 1998-11-02 1999-10-29 Derivate von aromaten und deren eisen komplexe zur verwendung als regulierungsmittel des eisenspiegels
IL142813A IL142813A (en) 1998-11-02 2001-04-25 Use of aromatic derivatives and iron complexes thereof in the preparation of pharmaceutical compositions for treating conditions to which an iron load is associated and pharmaceutical compositions comprising the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1998MI002350A IT1303688B1 (it) 1998-11-02 1998-11-02 Derivati aromatici e relativi complessi di fe(iii) atti all'usocome agenti normalizzanti del livello di ferro nell'organismo.

Publications (2)

Publication Number Publication Date
ITMI982350A1 ITMI982350A1 (it) 2000-05-02
IT1303688B1 true IT1303688B1 (it) 2001-02-23

Family

ID=11380986

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1998MI002350A IT1303688B1 (it) 1998-11-02 1998-11-02 Derivati aromatici e relativi complessi di fe(iii) atti all'usocome agenti normalizzanti del livello di ferro nell'organismo.

Country Status (17)

Country Link
US (1) US6455578B1 (it)
EP (1) EP1124814B1 (it)
JP (1) JP2002528539A (it)
AR (1) AR021037A1 (it)
AT (1) ATE229947T1 (it)
AU (1) AU756726B2 (it)
BR (1) BR9914863A (it)
CA (1) CA2348380C (it)
CZ (1) CZ299542B6 (it)
DE (1) DE69904635T2 (it)
DK (1) DK1124814T3 (it)
ES (1) ES2189537T3 (it)
IL (2) IL142813A0 (it)
IT (1) IT1303688B1 (it)
PL (1) PL198826B1 (it)
SK (1) SK286308B6 (it)
WO (1) WO2000026205A1 (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009531379A (ja) * 2006-03-29 2009-09-03 ビーエーエスエフ ソシエタス・ヨーロピア 鉄代謝機能障害を治療するためのストロビルリンの使用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4122200A (en) * 1974-11-20 1978-10-24 Lipha, Lyonnaise Industrielle Pharmaceutique 6',2-(2'Arylchromonyl) propionic acids, and analgesic and anti-inflammatory derivatives thereof
ATE14579T1 (de) * 1979-03-20 1985-08-15 Fisons Plc Pharmazeutische heterocyclische verbindungen, verfahren zu ihrer herstellung und sie enthaltende zusammensetzungen.
EP0346279A1 (de) * 1988-06-06 1989-12-13 Ciba-Geigy Ag Propan-1,3-dionderivate und deren Verwendung als Stabilisatoren für chlorhaltige Polymerisate

Also Published As

Publication number Publication date
BR9914863A (pt) 2001-07-03
CZ20011461A3 (cs) 2001-08-15
PL198826B1 (pl) 2008-07-31
IL142813A0 (en) 2002-03-10
JP2002528539A (ja) 2002-09-03
US6455578B1 (en) 2002-09-24
IL142813A (en) 2006-12-10
AR021037A1 (es) 2002-06-12
ATE229947T1 (de) 2003-01-15
PL347940A1 (en) 2002-04-22
SK286308B6 (en) 2008-07-07
CZ299542B6 (cs) 2008-08-27
SK5562001A3 (en) 2001-09-11
ITMI982350A1 (it) 2000-05-02
AU1157300A (en) 2000-05-22
CA2348380C (en) 2009-02-17
AU756726B2 (en) 2003-01-23
ES2189537T3 (es) 2003-07-01
DE69904635D1 (de) 2003-01-30
WO2000026205A1 (en) 2000-05-11
DE69904635T2 (de) 2003-10-02
EP1124814B1 (en) 2002-12-18
DK1124814T3 (da) 2003-04-14
CA2348380A1 (en) 2000-05-11
EP1124814A1 (en) 2001-08-22

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