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IT1276522B1 - Uso dello zolpidem per il trattamento terapeudico di sindromi neuropsichiatriche associate a disfunsione e di circuiti neurali dei - Google Patents

Uso dello zolpidem per il trattamento terapeudico di sindromi neuropsichiatriche associate a disfunsione e di circuiti neurali dei

Info

Publication number
IT1276522B1
IT1276522B1 IT95RM000223A ITRM950223A IT1276522B1 IT 1276522 B1 IT1276522 B1 IT 1276522B1 IT 95RM000223 A IT95RM000223 A IT 95RM000223A IT RM950223 A ITRM950223 A IT RM950223A IT 1276522 B1 IT1276522 B1 IT 1276522B1
Authority
IT
Italy
Prior art keywords
therapeudic
dysfunsion
zolpidem
treatment
neural circuits
Prior art date
Application number
IT95RM000223A
Other languages
English (en)
Inventor
Elena Benincasa
Original Assignee
Elena Benincasa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elena Benincasa filed Critical Elena Benincasa
Publication of ITRM950223A0 publication Critical patent/ITRM950223A0/it
Priority to IT95RM000223A priority Critical patent/IT1276522B1/it
Priority to EA199700308A priority patent/EA000396B1/ru
Priority to MX9707712A priority patent/MX9707712A/es
Priority to EP96907656A priority patent/EP0819002B1/en
Priority to DK96907656T priority patent/DK0819002T3/da
Priority to NZ304107A priority patent/NZ304107A/xx
Priority to JP53016596A priority patent/JP4049390B2/ja
Priority to CA002217590A priority patent/CA2217590C/en
Priority to PT96907656T priority patent/PT819002E/pt
Priority to DE69623271T priority patent/DE69623271T2/de
Priority to CNB961937815A priority patent/CN1198612C/zh
Priority to ES96907656T priority patent/ES2182967T3/es
Priority to CZ19973167A priority patent/CZ292020B6/cs
Priority to PL96322647A priority patent/PL322647A1/xx
Priority to HU9900733A priority patent/HUP9900733A3/hu
Priority to AT96907656T priority patent/ATE222763T1/de
Priority to AU51200/96A priority patent/AU707759B2/en
Priority to PCT/IT1996/000063 priority patent/WO1996031210A1/en
Priority to US08/930,644 priority patent/US5891891A/en
Priority to KR1019970707107A priority patent/KR100425628B1/ko
Priority to IL11782496A priority patent/IL117824A/xx
Priority to ZA962711A priority patent/ZA962711B/xx
Priority to ARP960102094A priority patent/AR003414A1/es
Priority to TW085104484A priority patent/TW450816B/zh
Publication of ITRM950223A1 publication Critical patent/ITRM950223A1/it
Priority to NO19974603A priority patent/NO315408B1/no
Application granted granted Critical
Publication of IT1276522B1 publication Critical patent/IT1276522B1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IT95RM000223A 1995-04-07 1995-04-07 Uso dello zolpidem per il trattamento terapeudico di sindromi neuropsichiatriche associate a disfunsione e di circuiti neurali dei IT1276522B1 (it)

Priority Applications (25)

Application Number Priority Date Filing Date Title
IT95RM000223A IT1276522B1 (it) 1995-04-07 1995-04-07 Uso dello zolpidem per il trattamento terapeudico di sindromi neuropsichiatriche associate a disfunsione e di circuiti neurali dei
CZ19973167A CZ292020B6 (cs) 1995-04-07 1996-04-02 Léčivo pro Parkinsonovy choroby
HU9900733A HUP9900733A3 (en) 1995-04-07 1996-04-02 Use of imidazo[1,2-a]pyridine-3-acetamide derivatives for the therapeutic treatment of neuropsychiatric syndromes associated with difunction of the neural circuits of the basal ganglia
EP96907656A EP0819002B1 (en) 1995-04-07 1996-04-02 USE OF IMIDAZO-[1,2-a]PYRIDINE-3-ACETAMIDE DERIVATIVES FOR THE THERAPEUTIC TREATMENT OF NEUROPSYCHIATRIC SYNDROMES ASSOCIATED WITH DISFUNCTION OF THE NEURAL CIRCUITS OF THE BASAL GANGLIA
DK96907656T DK0819002T3 (da) 1995-04-07 1996-04-02 Anvendelse af imidazo-[1,2-a]pyridin-3-acetamidderivater til den terapeutiske behandling af neuropsykiatriske syndromer, der er forbundet med dysfunktion af nervebanerne i basalganglierne
NZ304107A NZ304107A (en) 1995-04-07 1996-04-02 Use of imidazo[1,2-a]pyridine-3-acetamide derivatives for treating neuropsychiatric disorders
JP53016596A JP4049390B2 (ja) 1995-04-07 1996-04-02 基底核神経回路の不機能化に随伴する神経精神病症候群の治療のためのイミダゾ［１，２−ａ］ピリジン−３−アセトアミド誘導体の使用
CA002217590A CA2217590C (en) 1995-04-07 1996-04-02 Use of imidazo[1,2-a]pyridine-3-acetamide derivatives for the therapeutic treatment of neuropsychiatric syndromes associated with dysfunction of the neural circuits of the basal ganglia
PT96907656T PT819002E (pt) 1995-04-07 1996-04-02 Utilizacao de derivados de imidazol¬1,2-a|piridina-3-acetamida para o tratamento terapeutico de sindromas neuro-psiquiatricos associados com a disfuncao dos circuitos neurais dos ganglios basais
DE69623271T DE69623271T2 (de) 1995-04-07 1996-04-02 Verwendung von imidazo-(1,2-a)-pyridin-3-acetamid-derivaten für die therapeutische behandlung von neuropsychiatrischen syndromen in zusammenhang mit störungen der nervenbahnen der basalganglien
CNB961937815A CN1198612C (zh) 1995-04-07 1996-04-02 使用咪唑并[1,2－a]吡啶－3－乙酰胺衍生物治疗与基底神经节神经回路功能异常相关的神经精神综合症
ES96907656T ES2182967T3 (es) 1995-04-07 1996-04-02 Uso de derivados de imidazo[1,2-a(piridina-3-acetamida para el tr atamiento terapeutico de sindromes neuropsiquiatricos asociados con la disfuncion de los circuitos neuronales de los ganglios basales.
EA199700308A EA000396B1 (ru) 1995-04-07 1996-04-02 ПРИМЕНЕНИЕ ПРОИЗВОДНЫХ ИМИДАЗО[1,2-а]ПИРИДИН-3-АЦЕТАМИДА ДЛЯ ЛЕЧЕНИЯ НЕЙРОПСИХИАТРИЧЕСКИХ СИНДРОМОВ, СВЯЗАННЫХ С ДИСФУНКЦИЕЙ НЕРВНЫХ ЦЕПЕЙ БАЗАЛЬНЫХ ГАНГЛИЕВ
PL96322647A PL322647A1 (en) 1995-04-07 1996-04-02 Application of derivatives of imidazo [1,2-a] pyridino -3- acetamide in treating neuropsychiatric syndroms associated with disorders in functioning of neuronal circuits in the base of the brain
MX9707712A MX9707712A (es) 1995-04-07 1996-04-02 Uso de derivados de imidazo[1,2-a]piridina-3-acetamida para el tratamiento terapeutico de sindromes neuropsiquiatricos tales como degeneracion ganglionar cortical-basal.
AT96907656T ATE222763T1 (de) 1995-04-07 1996-04-02 Verwendung von imidazo-(1,2-a)-pyridin-3-acetamid-derivaten für die therapeutische behandlung von neuropsychiatrischen syndromen in zusammenhang mit störungen der nervenbahnen der basalganglien
AU51200/96A AU707759B2 (en) 1995-04-07 1996-04-02 Use of imidazo(1,2-a)pyridine-3-acetamide derivatives for the therapeutic treatment of neuropsychiatric syndromes associated with dysfunction of the neural circuits of the basal ganglia
PCT/IT1996/000063 WO1996031210A1 (en) 1995-04-07 1996-04-02 USE OF IMIDAZO[1,2-a]PYRIDINE-3-ACETAMIDE DERIVATIVES FOR THE THERAPEUTIC TREATMENT OF NEUROPSYCHIATRIC SYNDROMES ASSOCIATED WITH DISFUNCTION OF THE NEURAL CIRCUITS OF THE BASAL GANGLIA
US08/930,644 US5891891A (en) 1995-04-07 1996-04-02 Use of imidazo 1, 2-A! pyridine-3-acetamide derivatives for the therapeutic treatment of neuropsychiatric syndromes associated with disfunction of the neural circuits of the basal ganglia
KR1019970707107A KR100425628B1 (ko) 1995-04-07 1996-04-02 기저핵의신경회로의기능장애와연관된신경정신성증후군치료용이미다조[1,2-a]피리딘-3-아세트아미드유도체
IL11782496A IL117824A (en) 1995-04-07 1996-04-03 Pharmaceutical compositions containing 2-aryl-imidazol¬1,2-a¾pyridine-3-acetamide derivatives for treatment of neuropsychiatric syndromes associated with dysfunction of the neural circuits of the basal ganglia
ZA962711A ZA962711B (en) 1995-04-07 1996-04-04 Use of imidazol[1,2-a]pyridine-3-acetamide derivatives for the therapeutic treatment of neuropsychiatric syndromes associated with dysfunction of the neural circuits of the basal ganglia
ARP960102094A AR003414A1 (es) 1995-04-07 1996-04-08 Uso de derivados de imidazol [1,2-a]piridina -3-acetamida y una composicion farmaceutica que comprende tal derivado
TW085104484A TW450816B (en) 1995-04-07 1996-04-15 Pharmaceutical composition comprising imidazo [1,2-a]pyridine-3-acetamide derivatives for the treatment of neuropsychiatric syndromes associated with dysfunction of the neural circuits of the basal ganglia
NO19974603A NO315408B1 (no) 1995-04-07 1997-10-06 Anvendelse av imidazo[1,2-a]pyridin-3-acetamidderivater for terapeutisk behandling av neuropsykiatriske syndromer assosiert med disfunksjonav de sentraleområder av de basale ganglia

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT95RM000223A IT1276522B1 (it) 1995-04-07 1995-04-07 Uso dello zolpidem per il trattamento terapeudico di sindromi neuropsichiatriche associate a disfunsione e di circuiti neurali dei

Publications (3)

Publication Number Publication Date
ITRM950223A0 ITRM950223A0 (it) 1995-04-07
ITRM950223A1 ITRM950223A1 (it) 1996-10-07
IT1276522B1 true IT1276522B1 (it) 1997-10-31

Family

ID=11403250

Family Applications (1)

Application Number Title Priority Date Filing Date
IT95RM000223A IT1276522B1 (it) 1995-04-07 1995-04-07 Uso dello zolpidem per il trattamento terapeudico di sindromi neuropsichiatriche associate a disfunsione e di circuiti neurali dei

Country Status (25)

Country Link
US (1) US5891891A (it)
EP (1) EP0819002B1 (it)
JP (1) JP4049390B2 (it)
KR (1) KR100425628B1 (it)
CN (1) CN1198612C (it)
AR (1) AR003414A1 (it)
AT (1) ATE222763T1 (it)
AU (1) AU707759B2 (it)
CA (1) CA2217590C (it)
CZ (1) CZ292020B6 (it)
DE (1) DE69623271T2 (it)
DK (1) DK0819002T3 (it)
EA (1) EA000396B1 (it)
ES (1) ES2182967T3 (it)
HU (1) HUP9900733A3 (it)
IL (1) IL117824A (it)
IT (1) IT1276522B1 (it)
MX (1) MX9707712A (it)
NO (1) NO315408B1 (it)
NZ (1) NZ304107A (it)
PL (1) PL322647A1 (it)
PT (1) PT819002E (it)
TW (1) TW450816B (it)
WO (1) WO1996031210A1 (it)
ZA (1) ZA962711B (it)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7632517B2 (en) * 1997-10-01 2009-12-15 Novadel Pharma Inc. Buccal, polar and non-polar spray containing zolpidem
US6333345B1 (en) 1999-05-14 2001-12-25 Sepracor, Inc. Methods of using and compositions comprising N-desmethylzolpidem
US6399621B1 (en) 1999-08-10 2002-06-04 American Cyanamid Company N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1, 5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto
US6485746B1 (en) 2000-08-25 2002-11-26 Neurocrine Biosciences, Inc. Controlled-release sedative-hypnotic compositions and methods related thereto
US20030091632A1 (en) * 1999-08-26 2003-05-15 Neurocrine Biosciences, Inc. Controlled-release sedative-hypnotic compositions and methods related thereto
US6384221B1 (en) 1999-09-02 2002-05-07 Neurocrine Biosciences, Inc. Polymorphs of N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto
WO2001078725A2 (en) * 2000-04-13 2001-10-25 Synthon B.V. Modified release formulations containing a hypnotic agent
DE04010651T1 (de) * 2000-04-24 2005-09-01 Teva Pharmaceutical Industries Ltd. Mikronisiertes Zolpidem-Hemitartrat
DE10041478A1 (de) * 2000-08-24 2002-03-14 Sanol Arznei Schwarz Gmbh Neue pharmazeutische Zusammensetzung
DE10117183A1 (de) * 2001-04-05 2002-10-10 Gruenenthal Gmbh Verwendung von substituierten Imidazo[1,2-a]-pyridinverbindungen als Arzneimittel
JP2008506630A (ja) * 2003-05-19 2008-03-06 サイエンコム・リミテッド ゾルピデムの更なる治療的使用
GB0311457D0 (en) * 2003-05-19 2003-06-25 Sciencom Ltd New therapeutic use
DE10334187A1 (de) * 2003-07-26 2005-03-03 Schwarz Pharma Ag Substituierte 2-Aminotetraline zur Behandlung von Depressionen
DE10334188B4 (de) 2003-07-26 2007-07-05 Schwarz Pharma Ag Verwendung von Rotigotin zur Behandlung von Depressionen
PL1691811T3 (pl) 2003-12-11 2014-12-31 Sunovion Pharmaceuticals Inc Skojarzenie leku uspokajającego i modulatora neuroprzekaźnikowego oraz sposoby poprawy jakości snu i leczenia depresji
DE10361258A1 (de) 2003-12-24 2005-07-28 Schwarz Pharma Ag Verwendung von substituierten 2-Aminotetralinen zur vorbeugenden Behandlung von Morbus Parkinson
EP1742624B1 (en) 2004-02-18 2010-01-06 Sepracor, Inc. Dopamine-agonist combination therapy with sedatives for improving sleep quality
DE102004014841B4 (de) * 2004-03-24 2006-07-06 Schwarz Pharma Ag Verwendung von Rotigotin zur Behandlung und Prävention des Parkinson-Plus-Syndroms
KR101345468B1 (ko) * 2005-11-18 2013-12-30 신톤 비.브이. 졸피뎀 정제
WO2008056139A2 (en) * 2006-11-08 2008-05-15 Regen Therapeutics Plc Transdermal therapy
GB0809936D0 (en) * 2008-05-30 2008-07-09 Regen Therapeutics Plc Therapeutic use of zolpidem
US11547706B2 (en) 2016-06-08 2023-01-10 President And Fellows Of Harvard College Methods and compositions for reducing tactile dysfunction and anxiety associated with autism spectrum disorder, Rett syndrome, and Fragile X syndrome
US12252457B2 (en) 2018-05-22 2025-03-18 President And Fellows Of Harvard College Compositions and methods for reducing tactile dysfunction, anxiety, and social impairment
US11434244B2 (en) 2018-05-29 2022-09-06 President And Fellows Of Harvard College Compositions and methods for reducing tactile dysfunction, anxiety, and social impairment
EP3946390A4 (en) 2019-03-25 2022-12-21 President and Fellows of Harvard College COMPOSITIONS AND METHODS TO REDUCE TACTILE DYSFUNCTION, ANXIETY AND SOCIAL DISABILITIES

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FR2492382A1 (fr) * 1980-10-22 1982-04-23 Synthelabo Derives d'imidazo (1,2-a) pyridine, leur preparation et leur application en therapeutique
US5032595A (en) * 1989-11-24 1991-07-16 Fidia-Georgetown Institute For The Neurosciences Method of stimulating steroidogenesis with alpidem
US5206382A (en) * 1991-06-27 1993-04-27 Fidia Georgetown Institute For The Neurosciences Indole derivatives, pharmaceutical compositions and methods of treating neurological and psychiatric disorders

Also Published As

Publication number Publication date
KR100425628B1 (ko) 2004-06-23
AR003414A1 (es) 1998-08-05
ATE222763T1 (de) 2002-09-15
US5891891A (en) 1999-04-06
JPH11503149A (ja) 1999-03-23
AU5120096A (en) 1996-10-23
ITRM950223A1 (it) 1996-10-07
CN1198612C (zh) 2005-04-27
CZ292020B6 (cs) 2003-07-16
ES2182967T3 (es) 2003-03-16
JP4049390B2 (ja) 2008-02-20
MX9707712A (es) 1998-03-31
DK0819002T3 (da) 2003-01-06
AU707759B2 (en) 1999-07-22
ITRM950223A0 (it) 1995-04-07
WO1996031210A1 (en) 1996-10-10
EA000396B1 (ru) 1999-06-24
NO974603D0 (no) 1997-10-06
KR19980703707A (ko) 1998-12-05
DE69623271D1 (de) 2002-10-02
HUP9900733A3 (en) 2003-05-28
TW450816B (en) 2001-08-21
EP0819002B1 (en) 2002-08-28
NZ304107A (en) 2000-12-22
PL322647A1 (en) 1998-02-16
PT819002E (pt) 2003-01-31
ZA962711B (en) 1996-07-30
CZ316797A3 (cs) 1998-05-13
IL117824A0 (en) 1996-08-04
EA199700308A1 (ru) 1998-04-30
HUP9900733A2 (hu) 1999-07-28
CA2217590C (en) 2008-08-12
DE69623271T2 (de) 2003-07-24
NO315408B1 (no) 2003-09-01
EP0819002A1 (en) 1998-01-21
CA2217590A1 (en) 1996-10-10
IL117824A (en) 2000-08-31
NO974603L (no) 1997-11-24
CN1183719A (zh) 1998-06-03

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