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IT1255199B - Farmaco sintetizzato analogo della melatonina particolarmente efficacenelle patologie che interferiscono con i ritmi circadiani - Google Patents

Farmaco sintetizzato analogo della melatonina particolarmente efficacenelle patologie che interferiscono con i ritmi circadiani

Info

Publication number
IT1255199B
IT1255199B ITMI921612A ITMI921612A IT1255199B IT 1255199 B IT1255199 B IT 1255199B IT MI921612 A ITMI921612 A IT MI921612A IT MI921612 A ITMI921612 A IT MI921612A IT 1255199 B IT1255199 B IT 1255199B
Authority
IT
Italy
Prior art keywords
melatonin
particularly effective
interfer
pathologies
circadian rhythms
Prior art date
Application number
ITMI921612A
Other languages
English (en)
Inventor
Franco Fraschini
Aldo Laguzzi
Original Assignee
Franco Fraschini
Aldo Laguzzi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11363605&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IT1255199(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Franco Fraschini, Aldo Laguzzi filed Critical Franco Fraschini
Priority to ITMI921612A priority Critical patent/IT1255199B/it
Publication of ITMI921612A0 publication Critical patent/ITMI921612A0/it
Priority to EP93830269A priority patent/EP0585206B1/en
Priority to DE69327207T priority patent/DE69327207D1/de
Priority to AT93830269T priority patent/ATE187442T1/de
Priority to JP5159817A priority patent/JP2805575B2/ja
Publication of ITMI921612A1 publication Critical patent/ITMI921612A1/it
Priority to US08/196,380 priority patent/US5552428A/en
Application granted granted Critical
Publication of IT1255199B publication Critical patent/IT1255199B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Anesthesiology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Farmaco sintetizzato analogo della melatonina particolarmente efficace nelle patologie che interferiscono con i ritmi circadiani
ITMI921612A 1992-06-24 1992-07-01 Farmaco sintetizzato analogo della melatonina particolarmente efficacenelle patologie che interferiscono con i ritmi circadiani IT1255199B (it)

Priority Applications (6)

Application Number Priority Date Filing Date Title
ITMI921612A IT1255199B (it) 1992-07-01 1992-07-01 Farmaco sintetizzato analogo della melatonina particolarmente efficacenelle patologie che interferiscono con i ritmi circadiani
EP93830269A EP0585206B1 (en) 1992-07-01 1993-06-24 Tryptamines for treatment of circadian rhythm disorders
DE69327207T DE69327207D1 (de) 1992-07-01 1993-06-24 Tryptamine zur Behandlung von Störungen der circadianen Rhythmik
AT93830269T ATE187442T1 (de) 1992-07-01 1993-06-24 Tryptamine zur behandlung von störungen der circadianen rhythmik
JP5159817A JP2805575B2 (ja) 1992-07-01 1993-06-30 概日リズム治療用薬剤、これに用いる化合物およびその合成方法
US08/196,380 US5552428A (en) 1992-06-24 1994-02-15 Compounds effective in the treatment of circadian rhythms and related disorders, the novel pharmaceutical preparations and novel method of application

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI921612A IT1255199B (it) 1992-07-01 1992-07-01 Farmaco sintetizzato analogo della melatonina particolarmente efficacenelle patologie che interferiscono con i ritmi circadiani

Publications (3)

Publication Number Publication Date
ITMI921612A0 ITMI921612A0 (it) 1992-07-01
ITMI921612A1 ITMI921612A1 (it) 1994-01-01
IT1255199B true IT1255199B (it) 1995-10-20

Family

ID=11363605

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI921612A IT1255199B (it) 1992-06-24 1992-07-01 Farmaco sintetizzato analogo della melatonina particolarmente efficacenelle patologie che interferiscono con i ritmi circadiani

Country Status (5)

Country Link
EP (1) EP0585206B1 (it)
JP (1) JP2805575B2 (it)
AT (1) ATE187442T1 (it)
DE (1) DE69327207D1 (it)
IT (1) IT1255199B (it)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6180657B1 (en) * 1993-11-18 2001-01-30 Eli Lilly And Company Melatonin derivatives for use in treating desynchronization disorders
US5654325A (en) * 1993-11-18 1997-08-05 Eli Lilly And Company Melatonin derivatives for use in treating sleep disorders
JPH09511334A (ja) 1994-03-30 1997-11-11 チバ−ガイギー アクチェンゲゼルシャフト Ｒｚｒ受容体ファミリーを用いるスクリーニング方法
FR2737725B1 (fr) * 1995-08-08 1997-10-31 Valentonine Nouveaux derives acyles de la melatonine et d'analogues melatoninergiques, leur procede de preparation et leur utilisation en tant que medicament
AU1698899A (en) * 1997-11-04 1999-05-24 St. Elizabeth's Medical Center Of Boston, Inc. N-acetylserotonin derivatives and uses thereof
US8053462B2 (en) 2004-03-08 2011-11-08 Masanori Somei Indole derivative and application thereof
JP3964417B2 (ja) 2004-09-27 2007-08-22 国立大学法人金沢大学 インドール誘導体を有効成分とするα２受容体遮断剤及び血管拡張剤
CN116348106A (zh) * 2020-09-01 2023-06-27 恩维瑞克生物科学加拿大公司 卤代裸盖菇素衍生物及使用方法
CN113480467B (zh) * 2021-07-13 2022-12-30 河北维达康生物科技有限公司 一种放射性示踪剂2-碘褪黑素的合成工艺

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3466215D1 (en) * 1983-05-18 1987-10-22 Univ Monash The use of melatonin for the manufacture of a medicament
WO1989001472A1 (en) * 1987-08-17 1989-02-23 Nelson Research & Development Co. Melatonin analogues
DK0483077T3 (da) * 1990-09-28 1996-04-15 I F L O S A S Di Giorgio E Ald Fremgangsmåde til syntese af et kontraceptivt og menstruationscyklus-kontrollerende lægemiddel med onkostatiske, antikinetosiske, præventive og terapeutiske egenskaber til behandling af brysttumorer og melanomer
IT1251544B (it) * 1991-05-13 1995-05-17 Gabriele Biella Composizioni farmaceutiche attive nella terapia dei disturbi del sonno comprendenti melatonina o un suo derivato in associazione con un derivato benzodiazepinico

Also Published As

Publication number Publication date
JP2805575B2 (ja) 1998-09-30
DE69327207D1 (de) 2000-01-13
ITMI921612A0 (it) 1992-07-01
EP0585206A1 (en) 1994-03-02
EP0585206B1 (en) 1999-12-08
ITMI921612A1 (it) 1994-01-01
ATE187442T1 (de) 1999-12-15
JPH06183968A (ja) 1994-07-05

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960623