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IT1250410B - Composti steroidei attivi sul sistema cardiovascolare - Google Patents

Composti steroidei attivi sul sistema cardiovascolare

Info

Publication number
IT1250410B
IT1250410B ITMI910380A ITMI910380A IT1250410B IT 1250410 B IT1250410 B IT 1250410B IT MI910380 A ITMI910380 A IT MI910380A IT MI910380 A ITMI910380 A IT MI910380A IT 1250410 B IT1250410 B IT 1250410B
Authority
IT
Italy
Prior art keywords
cardiovascular system
steroid compounds
compounds active
formula
active
Prior art date
Application number
ITMI910380A
Other languages
English (en)
Inventor
Giorgio Bertolini
Cesare Casagrande
Stefania Montanari
Gabriele Norcini
Francesco Santangelo
Original Assignee
Simes
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Simes filed Critical Simes
Priority to ITMI910380A priority Critical patent/IT1250410B/it
Publication of ITMI910380A0 publication Critical patent/ITMI910380A0/it
Priority to DE69215125T priority patent/DE69215125T2/de
Priority to EP92200375A priority patent/EP0499327B1/en
Priority to AT92200375T priority patent/ATE145213T1/de
Priority to ES92200375T priority patent/ES2096014T3/es
Priority to US07/834,769 priority patent/US5426179A/en
Priority to JP4028164A priority patent/JPH0565293A/ja
Publication of ITMI910380A1 publication Critical patent/ITMI910380A1/it
Application granted granted Critical
Publication of IT1250410B publication Critical patent/IT1250410B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/001—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class spiro-linked
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/001—Lactones
    • C07J21/003—Lactones at position 17

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Vengono descritti composti steroidei attivi sul sistema cardiovascolare di formula (FORMULA I) in cui X, n, R, R1 ed R2, hanno i significati riportati nella descrizione.
ITMI910380A 1991-02-14 1991-02-14 Composti steroidei attivi sul sistema cardiovascolare IT1250410B (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
ITMI910380A IT1250410B (it) 1991-02-14 1991-02-14 Composti steroidei attivi sul sistema cardiovascolare
DE69215125T DE69215125T2 (de) 1991-02-14 1992-02-11 Kardioaktive Steroide
EP92200375A EP0499327B1 (en) 1991-02-14 1992-02-11 Steroid compounds active on the cardiovascular system
AT92200375T ATE145213T1 (de) 1991-02-14 1992-02-11 Kardioaktive steroide
ES92200375T ES2096014T3 (es) 1991-02-14 1992-02-11 Compuestos esteroides activos sobre el sistema cardiovascular.
US07/834,769 US5426179A (en) 1991-02-14 1992-02-12 Steroid compounds active on the cardiovascular system
JP4028164A JPH0565293A (ja) 1991-02-14 1992-02-14 心臓血管系に作用するステロイド化合物およびそれを含む薬剤

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI910380A IT1250410B (it) 1991-02-14 1991-02-14 Composti steroidei attivi sul sistema cardiovascolare

Publications (3)

Publication Number Publication Date
ITMI910380A0 ITMI910380A0 (it) 1991-02-14
ITMI910380A1 ITMI910380A1 (it) 1992-08-15
IT1250410B true IT1250410B (it) 1995-04-07

Family

ID=11358571

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI910380A IT1250410B (it) 1991-02-14 1991-02-14 Composti steroidei attivi sul sistema cardiovascolare

Country Status (7)

Country Link
US (1) US5426179A (it)
EP (1) EP0499327B1 (it)
JP (1) JPH0565293A (it)
AT (1) ATE145213T1 (it)
DE (1) DE69215125T2 (it)
ES (1) ES2096014T3 (it)
IT (1) IT1250410B (it)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4232681C2 (de) * 1992-09-29 1994-11-24 Sigma Tau Ind Farmaceuti 17-Phenyl- und 17-Furyl-14beta,5alpha-androstan- und androsten- Derivate, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zusammensetzung
US5597806A (en) * 1995-05-09 1997-01-28 Merck & Co., Inc. Antifungal agents
DE69942578D1 (de) 1998-05-22 2010-08-26 Univ R Bifunktionelle moleküle sowie darauf basierende therapien.
DK1889198T3 (da) 2005-04-28 2015-02-09 Proteus Digital Health Inc Farma-informatiksystem
US9062126B2 (en) 2005-09-16 2015-06-23 Raptor Pharmaceuticals Inc. Compositions comprising receptor-associated protein (RAP) variants specific for CR-containing proteins and uses thereof
AU2010216512B2 (en) 2009-02-20 2016-06-30 2-Bbb Medicines B.V. Glutathione-based drug delivery system
MY163048A (en) 2009-05-06 2017-08-15 Laboratory Skin Care Inc Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
EP3664470B1 (en) 2018-12-05 2021-02-17 Sonova AG Providing feedback of an own voice loudness of a user of a hearing device

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3968132A (en) * 1974-12-23 1976-07-06 Schering Corporation (17R)-Spiro-[androstane-17,1'-cyclobutan]-2'-ones, methods for their manufacture and intermediates useful therein
DE2546779A1 (de) * 1975-10-18 1977-04-28 Boehringer Mannheim Gmbh Neue 20.22-dihydro-cardenolid- glykoside
FR2451923A1 (fr) * 1979-03-22 1980-10-17 Roussel Uclaf Nouveaux derives steroides 7-alkyles, leur procede de preparation et leur application comme medicament

Also Published As

Publication number Publication date
DE69215125D1 (de) 1996-12-19
US5426179A (en) 1995-06-20
ES2096014T3 (es) 1997-03-01
EP0499327B1 (en) 1996-11-13
ATE145213T1 (de) 1996-11-15
DE69215125T2 (de) 1997-06-12
ITMI910380A1 (it) 1992-08-15
JPH0565293A (ja) 1993-03-19
EP0499327A1 (en) 1992-08-19
ITMI910380A0 (it) 1991-02-14

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960123