IT1248669B - Derivato di idrossiprolina, sua preparazione e composizioni farmaceutiche che lo contengono - Google Patents
Derivato di idrossiprolina, sua preparazione e composizioni farmaceutiche che lo contengonoInfo
- Publication number
- IT1248669B IT1248669B IT02048390A IT2048390A IT1248669B IT 1248669 B IT1248669 B IT 1248669B IT 02048390 A IT02048390 A IT 02048390A IT 2048390 A IT2048390 A IT 2048390A IT 1248669 B IT1248669 B IT 1248669B
- Authority
- IT
- Italy
- Prior art keywords
- preparation
- derivate
- hydroxyproline
- contain
- pharmaceutical compositions
- Prior art date
Links
- PMMYEEVYMWASQN-DMTCNVIQSA-N Hydroxyproline Chemical compound O[C@H]1CN[C@H](C(O)=O)C1 PMMYEEVYMWASQN-DMTCNVIQSA-N 0.000 title 1
- PMMYEEVYMWASQN-UHFFFAOYSA-N dl-hydroxyproline Natural products OC1C[NH2+]C(C([O-])=O)C1 PMMYEEVYMWASQN-UHFFFAOYSA-N 0.000 title 1
- 229960002591 hydroxyproline Drugs 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- FGMPLJWBKKVCDB-UHFFFAOYSA-N trans-L-hydroxy-proline Natural products ON1CCCC1C(O)=O FGMPLJWBKKVCDB-UHFFFAOYSA-N 0.000 title 1
- UALJSXIPZBZMGU-UHFFFAOYSA-N 4-(thiophene-2-carbonyloxy)pyrrolidine-2-carboxylic acid Chemical compound C1NC(C(=O)O)CC1OC(=O)C1=CC=CS1 UALJSXIPZBZMGU-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 230000000083 anti-dystrophic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT02048390A IT1248669B (it) | 1990-05-30 | 1990-05-30 | Derivato di idrossiprolina, sua preparazione e composizioni farmaceutiche che lo contengono |
| AU75861/91A AU7586191A (en) | 1990-05-30 | 1991-04-02 | Hydroxyproline derivative, a process for the preparation thereof and pharmaceutical compositions containing it |
| EP91907069A EP0532506B1 (en) | 1990-05-30 | 1991-04-02 | 4-[(Thiophene-2-carbonyl)oxy]pyrrolidine-2-carboxylic acid, its preparation and its use as anti-inflammatory and anti-dystrophic agent |
| AT91907069T ATE129244T1 (de) | 1990-05-30 | 1991-04-02 | 4-((thiophen-2-carbonyl)oxy>pyrrolidin-2- carbonsäure, deren herstellung und deren verwendung als entzündungshemmendes und wundheilendes mittel. |
| DE69114005T DE69114005T2 (de) | 1990-05-30 | 1991-04-02 | 4-[(Thiophen-2-carbonyl)oxy]pyrrolidin-2-carbonsäure, deren Herstellung und deren Verwendung als entzündungshemmendes und wundheilendes Mittel. |
| ES91907069T ES2079650T3 (es) | 1990-05-30 | 1991-04-02 | Acido 4-((tiofeno-2-carbonil)oxi)pirrolidin-2-carboxilico, su preparacion y su uso como agente antiinflamatorio y antidistrofico. |
| PCT/EP1991/000622 WO1991018896A1 (en) | 1990-05-30 | 1991-04-02 | Hydroxyproline derivative, a process for the preparation thereof and pharmaceutical compositions containing it |
| GR950403243T GR3018126T3 (en) | 1990-05-30 | 1995-11-21 | 4-[(Thiophene-2-carbonyl)oxy]pyrrolidine-2-carboxylic acid, its preparation and its use as anti-inflammatory and anti-dystrophic agent. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT02048390A IT1248669B (it) | 1990-05-30 | 1990-05-30 | Derivato di idrossiprolina, sua preparazione e composizioni farmaceutiche che lo contengono |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| IT9020483A0 IT9020483A0 (it) | 1990-05-30 |
| IT9020483A1 IT9020483A1 (it) | 1991-11-30 |
| IT1248669B true IT1248669B (it) | 1995-01-26 |
Family
ID=11167627
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT02048390A IT1248669B (it) | 1990-05-30 | 1990-05-30 | Derivato di idrossiprolina, sua preparazione e composizioni farmaceutiche che lo contengono |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0532506B1 (it) |
| AT (1) | ATE129244T1 (it) |
| AU (1) | AU7586191A (it) |
| DE (1) | DE69114005T2 (it) |
| ES (1) | ES2079650T3 (it) |
| GR (1) | GR3018126T3 (it) |
| IT (1) | IT1248669B (it) |
| WO (1) | WO1991018896A1 (it) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0906096B1 (de) * | 1996-04-16 | 2002-06-26 | Chephasaar Chem.-Pharm. Fabrik GmbH | Verwendung von hydroxyprolinen zur herstellung eines arzneimittels zur hemmung der leukozyteninvasion in gewebe |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1795327C3 (de) * | 1967-09-14 | 1979-09-13 | S.A.R.L. Franco-Chimie, Paris | Verwendung von N-Acetyl-1-Hydroxyprolin |
| FR2152456B1 (it) * | 1971-09-16 | 1974-10-18 | Morelle Jean |
-
1990
- 1990-05-30 IT IT02048390A patent/IT1248669B/it active IP Right Grant
-
1991
- 1991-04-02 AT AT91907069T patent/ATE129244T1/de not_active IP Right Cessation
- 1991-04-02 EP EP91907069A patent/EP0532506B1/en not_active Expired - Lifetime
- 1991-04-02 DE DE69114005T patent/DE69114005T2/de not_active Expired - Fee Related
- 1991-04-02 ES ES91907069T patent/ES2079650T3/es not_active Expired - Lifetime
- 1991-04-02 AU AU75861/91A patent/AU7586191A/en not_active Abandoned
- 1991-04-02 WO PCT/EP1991/000622 patent/WO1991018896A1/en active IP Right Grant
-
1995
- 1995-11-21 GR GR950403243T patent/GR3018126T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0532506A1 (en) | 1993-03-24 |
| ES2079650T3 (es) | 1996-01-16 |
| ATE129244T1 (de) | 1995-11-15 |
| GR3018126T3 (en) | 1996-02-29 |
| AU7586191A (en) | 1991-12-31 |
| EP0532506B1 (en) | 1995-10-18 |
| IT9020483A1 (it) | 1991-11-30 |
| IT9020483A0 (it) | 1990-05-30 |
| DE69114005T2 (de) | 1996-06-05 |
| WO1991018896A1 (en) | 1991-12-12 |
| DE69114005D1 (de) | 1995-11-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SE8700499D0 (sv) | Novel pharmacologically active compounds | |
| RU95101048A (ru) | Производные пролинамида, фармкомпозиция на их основе | |
| RU94041223A (ru) | Средство для лечения мотонейроновых заболеваний | |
| RU93004970A (ru) | Производные циклоалкилзамещенного глутарамида, их применение, фармацевтическая композиция | |
| BR9812492A (pt) | Composto, uso do mesmo, formulação farmacêutica, e, processos para o tratamento de uma doença cardiovascular, para o tratamento de uma vasoconstrição, e para a preparação de compostos | |
| PT97395A (pt) | Processo para a preparacao de 2,9-di-substituidas-4h-pirido{1,2-a}-pirimidin-4-onas e de composicoes farmaceuticas que os contem | |
| ATE110365T1 (de) | 2-alkyl-4-arylmethylaminochinoline, ihre verwendung und daraus hergestellte arzneimittel. | |
| LV10267A (lv) | Savienojums arstniecibas lidzeklis panemiens savienojuma iegusanai | |
| EA200000242A1 (ru) | Применение фанхинона для лечения болезни альцгеймера | |
| IE780217L (en) | 1,3,5-triazine-2,6-dione derivatives | |
| SE9504662D0 (sv) | New compounds | |
| BR9811954A (pt) | ácidos 3-aril-succinamido-hidroxâmicos, processos para sua produção e preparações farmacêuticas contendo estas substâncias | |
| FI65616B (fi) | Foerfarande foer framstaellning av farmaceutiskt anvaendbara 1-oxadiazolylfenoxi-3-(4-fenylpiperazinyl)-propanol-2-derivat | |
| PT1017681E (pt) | Derivados de hidrazono-benzazuleno composicoes farmaceuticas e intermediarios | |
| IT1248669B (it) | Derivato di idrossiprolina, sua preparazione e composizioni farmaceutiche che lo contengono | |
| DE69103773D1 (de) | Derivate von hydroxaminsäure die lipoxygenase hemmen. | |
| ES2164168T3 (es) | Antagonistas de receptores de fibrinogeno que tienen residuos de beta-aminoacido sustituidos y composiciones farmaceuticas que comprenden los mismos. | |
| NO913644D0 (no) | Fremgangsmaate for fremstilling av terapeutisk aktive aminosyrederivater. | |
| ES2076054T3 (es) | Nuevas amino-alquil-cromonas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen. | |
| RU95102147A (ru) | Производные 1-[2-(1н-инден-3-ил)этил]-4-(нафт-1-ил)пиперазина, способ их получения и содержащие их медикамент и фармацевтический состав | |
| ATE149T1 (de) | 2-(n-(2'-chlor-4'-methylthienyl-3')-n-(cyclopropyl- methyl)-amino)-imidazolin-(2), dessen saeureadditionssalze, dieses enthaltende arzneimittel und verfahren zu seiner herstellung. | |
| DK0445894T3 (da) | Anvendelse af tumornekrosefaktor | |
| EA200000168A1 (ru) | Фармацевтическая композиция, снижающая продуцирование белка мср-1 | |
| ATE10934T1 (de) | Peptid, verfahren zu dessen herstellung und dessen verwendung. | |
| SE9003040D0 (sv) | Analogues of cyclolinopeptide a and the use thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970529 |