IT1243724B - Process for the preparation of L-alpha-glyceryl- phosphorylcholine - Google Patents
Process for the preparation of L-alpha-glyceryl- phosphorylcholineInfo
- Publication number
- IT1243724B IT1243724B IT02151490A IT2151490A IT1243724B IT 1243724 B IT1243724 B IT 1243724B IT 02151490 A IT02151490 A IT 02151490A IT 2151490 A IT2151490 A IT 2151490A IT 1243724 B IT1243724 B IT 1243724B
- Authority
- IT
- Italy
- Prior art keywords
- phosphorylcholine
- glyceryl
- preparation
- alpha
- resins
- Prior art date
Links
- 239000008777 Glycerylphosphorylcholine Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- SUHOQUVVVLNYQR-MRVPVSSYSA-N choline alfoscerate Chemical compound C[N+](C)(C)CCOP([O-])(=O)OC[C@H](O)CO SUHOQUVVVLNYQR-MRVPVSSYSA-N 0.000 title 1
- 229960004956 glycerylphosphorylcholine Drugs 0.000 abstract 2
- SUHOQUVVVLNYQR-MRVPVSSYSA-O glycerylphosphorylcholine Chemical compound C[N+](C)(C)CCO[P@](O)(=O)OC[C@H](O)CO SUHOQUVVVLNYQR-MRVPVSSYSA-O 0.000 abstract 2
- XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl trichloride Chemical compound ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 abstract 2
- 229920005989 resin Polymers 0.000 abstract 2
- 239000011347 resin Substances 0.000 abstract 2
- 125000002091 cationic group Chemical group 0.000 abstract 1
- FRMZOWIQVCBEAC-UHFFFAOYSA-N glycerylphosphorylethanolamine Chemical compound OCCN(P(O)(O)=O)CC(O)CO FRMZOWIQVCBEAC-UHFFFAOYSA-N 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
A process is described for the preparation of glyceryl- phosphorylcholine from glyceroacetone and phosphorus oxychloride and the purification of glycerylphosphoryl- choline and glycerylphosphorylethanolamine on cationic resins and strong basic resins.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT02151490A IT1243724B (en) | 1990-09-19 | 1990-09-19 | Process for the preparation of L-alpha-glyceryl- phosphorylcholine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT02151490A IT1243724B (en) | 1990-09-19 | 1990-09-19 | Process for the preparation of L-alpha-glyceryl- phosphorylcholine |
Publications (3)
Publication Number | Publication Date |
---|---|
IT9021514A0 IT9021514A0 (en) | 1990-09-19 |
IT9021514A1 IT9021514A1 (en) | 1992-03-19 |
IT1243724B true IT1243724B (en) | 1994-06-21 |
Family
ID=11182942
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT02151490A IT1243724B (en) | 1990-09-19 | 1990-09-19 | Process for the preparation of L-alpha-glyceryl- phosphorylcholine |
Country Status (1)
Country | Link |
---|---|
IT (1) | IT1243724B (en) |
-
1990
- 1990-09-19 IT IT02151490A patent/IT1243724B/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
IT9021514A0 (en) | 1990-09-19 |
IT9021514A1 (en) | 1992-03-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970926 |