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IT1228934B - Derivati dell'acido 7-ossabiciclo (2.2.1.) eptan idrossammico utili come inibitori duplici - Google Patents

Derivati dell'acido 7-ossabiciclo (2.2.1.) eptan idrossammico utili come inibitori duplici

Info

Publication number
IT1228934B
IT1228934B IT8721697A IT2169787A IT1228934B IT 1228934 B IT1228934 B IT 1228934B IT 8721697 A IT8721697 A IT 8721697A IT 2169787 A IT2169787 A IT 2169787A IT 1228934 B IT1228934 B IT 1228934B
Authority
IT
Italy
Prior art keywords
oxabicycid
duplic
eptan
hydroxamic
inhibitors
Prior art date
Application number
IT8721697A
Other languages
English (en)
Other versions
IT8721697A0 (it
Inventor
Eric Michael Gordon
Ravi Kannadikovilakom Varma
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of IT8721697A0 publication Critical patent/IT8721697A0/it
Application granted granted Critical
Publication of IT1228934B publication Critical patent/IT1228934B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT8721697A 1986-08-26 1987-08-24 Derivati dell'acido 7-ossabiciclo (2.2.1.) eptan idrossammico utili come inibitori duplici IT1228934B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/900,565 US4672075A (en) 1986-08-26 1986-08-26 7-Oxabicyclo(2.2.1)heptane hydroxamic acid derivatives useful as antiinflammatory, antiasthma and antipsoriatic agents

Publications (2)

Publication Number Publication Date
IT8721697A0 IT8721697A0 (it) 1987-08-24
IT1228934B true IT1228934B (it) 1991-07-10

Family

ID=25412729

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8721697A IT1228934B (it) 1986-08-26 1987-08-24 Derivati dell'acido 7-ossabiciclo (2.2.1.) eptan idrossammico utili come inibitori duplici

Country Status (7)

Country Link
US (1) US4672075A (it)
JP (1) JPS6360988A (it)
CA (1) CA1301179C (it)
DE (1) DE3728350A1 (it)
FR (1) FR2603284B1 (it)
GB (1) GB2194531B (it)
IT (1) IT1228934B (it)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4672075A (en) * 1986-08-26 1987-06-09 E. R. Squibb & Sons 7-Oxabicyclo(2.2.1)heptane hydroxamic acid derivatives useful as antiinflammatory, antiasthma and antipsoriatic agents
US4707494A (en) * 1986-08-26 1987-11-17 E. R. Squibb & Sons, Inc. 7-oxabicyclo(2.2.1)heptane compounds useful in the treatment of inflammation
US5112846A (en) * 1989-05-26 1992-05-12 Warner-Lambert Company N-hydroxyamide, N-hydroxythioamide, hydroxyurea, and N-hydroxythiourea derivatives of selected nsaids as antiinflammatory agents
US4981865A (en) * 1989-05-26 1991-01-01 Warner-Lambert Co. N-hydroxyamide, N-hydroxythioamide, hydroxyurea, and N-hydroxythiourea derivatives of selected nsaids as antiinflammatory agents
US5075330A (en) * 1989-05-26 1991-12-24 Warner-Lambert Co. N-hydroxyamide, N-hydroxythioamide, N-hydroxyurea, and N-hydroxythiourea derivatives of selected NSAIDS as antiinflammatory agents
CN102413825A (zh) 2009-04-29 2012-04-11 阿马里纳股份公司 含有epa和心血管剂的药物组合物以及使用其的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4143054A (en) * 1977-11-04 1979-03-06 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane- and 7-oxabicycloheptene compounds
US4254044A (en) * 1977-11-04 1981-03-03 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane- and 7-oxabicycloheptene compounds
US4228180A (en) * 1979-11-01 1980-10-14 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane and 7-oxabicycloheptene prostaglandin analogs
JPS58113152A (ja) * 1981-12-28 1983-07-05 Ono Pharmaceut Co Ltd ２−アミノフエノ−ル誘導体、その製造方法およびそれらを有効成分として含有する治療剤
US4497827A (en) * 1982-08-30 1985-02-05 Syntex (U.S.A.) Inc. Arachidonic acid analogues as anti-inflammatory and anti-allergic agents
US4582854A (en) * 1983-03-14 1986-04-15 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted oxa prostaglandin analgos useful in the treatment of thrombolytic disease
US4661506A (en) * 1984-11-30 1987-04-28 E. R. Squibb & Sons, Inc. 7-oxabicycloheptane substituted ox prostaglandin analogs
US4604407A (en) * 1985-04-04 1986-08-05 E. R. Squibb & Sons, Inc. Hydroxamates
US4672075A (en) * 1986-08-26 1987-06-09 E. R. Squibb & Sons 7-Oxabicyclo(2.2.1)heptane hydroxamic acid derivatives useful as antiinflammatory, antiasthma and antipsoriatic agents

Also Published As

Publication number Publication date
FR2603284A1 (fr) 1988-03-04
GB2194531A (en) 1988-03-09
FR2603284B1 (fr) 1990-11-16
GB2194531B (en) 1990-07-18
DE3728350A1 (de) 1988-03-03
US4672075A (en) 1987-06-09
IT8721697A0 (it) 1987-08-24
GB8717818D0 (en) 1987-09-03
JPS6360988A (ja) 1988-03-17
CA1301179C (en) 1992-05-19

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Effective date: 19950830