IT1203743B - Peptidi e derivati peptidici,loro preparazione e loro impiego come medicamenti - Google Patents
Peptidi e derivati peptidici,loro preparazione e loro impiego come medicamentiInfo
- Publication number
- IT1203743B IT1203743B IT47666/86A IT4766686A IT1203743B IT 1203743 B IT1203743 B IT 1203743B IT 47666/86 A IT47666/86 A IT 47666/86A IT 4766686 A IT4766686 A IT 4766686A IT 1203743 B IT1203743 B IT 1203743B
- Authority
- IT
- Italy
- Prior art keywords
- peptidal
- medications
- peptides
- derivatives
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US70265185A | 1985-02-19 | 1985-02-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8647666A0 IT8647666A0 (it) | 1986-02-18 |
IT1203743B true IT1203743B (it) | 1989-02-23 |
Family
ID=24822094
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT47666/86A IT1203743B (it) | 1985-02-19 | 1986-02-18 | Peptidi e derivati peptidici,loro preparazione e loro impiego come medicamenti |
Country Status (7)
Country | Link |
---|---|
JP (1) | JPS61194097A (it) |
BE (1) | BE904233A (it) |
CH (1) | CH672792A5 (it) |
DE (1) | DE3604510A1 (it) |
FR (1) | FR2577557B1 (it) |
GB (1) | GB2171103B (it) |
IT (1) | IT1203743B (it) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8600263D0 (en) * | 1985-01-22 | 1986-02-12 | Ici America Inc | Peptide derivatives |
US5055450A (en) * | 1985-01-22 | 1991-10-08 | Ici Americas Inc. | Peptide derivatives |
US5194588A (en) * | 1985-01-22 | 1993-03-16 | Ici Americas Inc. | Aminoalcohol intermediates for peptide derivatives |
US5496927A (en) * | 1985-02-04 | 1996-03-05 | Merrell Pharmaceuticals Inc. | Peptidase inhibitors |
US4882420A (en) * | 1985-04-19 | 1989-11-21 | The Upjohn Company | Dihalo-statine substituted renin inhibitors |
GB8613704D0 (en) * | 1986-06-05 | 1986-07-09 | Ici America Inc | Difluoro keto compounds |
GB8613703D0 (en) * | 1986-06-05 | 1986-07-09 | Ici America Inc | Difluoro peptide compounds |
GB8619182D0 (en) * | 1986-08-06 | 1986-09-17 | Sandoz Ltd | Peptides & derivatives |
NZ223148A (en) * | 1987-01-16 | 1989-10-27 | Merrell Dow Pharma | Peptide derivatives having peptidase inhibition activity |
US4855303A (en) * | 1987-07-01 | 1989-08-08 | Pfizer Inc. | Fluorine containing renin inhibitors |
US5071837A (en) * | 1990-11-28 | 1991-12-10 | Warner-Lambert Company | Novel renin inhibiting peptides |
NZ241099A (en) * | 1991-01-02 | 1994-08-26 | Merrell Dow Pharma | Difluorostatone analogues and derivatives and pharmaceutical compositions |
US5559140A (en) * | 1991-01-02 | 1996-09-24 | Merrell Pharmaceuticals Inc. | Difluoro statone analogs |
IL108031A0 (en) * | 1992-12-22 | 1994-04-12 | Procter & Gamble | Difluoro pentapeptide derivatives and pharmaceutical compositions containing them |
AU667995B2 (en) * | 1993-02-15 | 1996-04-18 | Bayer Aktiengesellschaft | New pseudopeptides having an antiviral action |
WO1995001958A1 (en) * | 1993-07-08 | 1995-01-19 | Merrell Pharmaceuticals Inc. | Difluoro statone analogs |
KR100308839B1 (ko) * | 1993-09-09 | 2002-10-04 | 메렐 파마슈티칼스 인크. | 디플루오로 스타톤 항바이러스성 유사체 |
EP0742791B1 (en) * | 1994-02-04 | 2001-01-10 | Merrell Pharmaceuticals Inc. | Macrocyclic difluorostatone derivatives useful as antiviral agents |
GB9502152D0 (en) * | 1995-02-03 | 1995-03-29 | Zeneca Ltd | Proline derivatives |
US6114380A (en) * | 1995-12-18 | 2000-09-05 | Merrell Pharmaceuticals Inc. | Difluoro statone analogs |
US8324347B2 (en) * | 2009-02-24 | 2012-12-04 | Institute For Systems Biology | Methods of using halogenated peptides as internal standards for liquid chromatography-mass spectrometry |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2424253A1 (fr) * | 1978-04-27 | 1979-11-23 | Brun Lab Sa Le | Nouveaux derives de peptides analogues des enkephalines, leur procede de preparation et leur application therapeutique |
GR75019B (it) * | 1980-09-17 | 1984-07-12 | Univ Miami | |
EP0218688B1 (en) * | 1985-04-19 | 1990-09-12 | The Upjohn Company | Dihalo-statine substituted renin inhibitors |
-
1986
- 1986-02-11 CH CH537/86A patent/CH672792A5/de not_active IP Right Cessation
- 1986-02-13 DE DE19863604510 patent/DE3604510A1/de not_active Withdrawn
- 1986-02-17 BE BE1/011438A patent/BE904233A/fr not_active IP Right Cessation
- 1986-02-17 GB GB08603835A patent/GB2171103B/en not_active Expired
- 1986-02-17 FR FR868602218A patent/FR2577557B1/fr not_active Expired - Lifetime
- 1986-02-18 IT IT47666/86A patent/IT1203743B/it active
- 1986-02-18 JP JP61034930A patent/JPS61194097A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
BE904233A (fr) | 1986-08-18 |
JPS61194097A (ja) | 1986-08-28 |
GB2171103A (en) | 1986-08-20 |
DE3604510A1 (de) | 1986-08-21 |
FR2577557A1 (fr) | 1986-08-22 |
GB8603835D0 (en) | 1986-03-26 |
FR2577557B1 (fr) | 1990-05-11 |
CH672792A5 (it) | 1989-12-29 |
IT8647666A0 (it) | 1986-02-18 |
GB2171103B (en) | 1989-01-25 |
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