IT1195304B - Metodo per la preparazione di gem-diammino derivati n-monoacilati - Google Patents
Metodo per la preparazione di gem-diammino derivati n-monoacilatiInfo
- Publication number
- IT1195304B IT1195304B IT25755/81A IT2575581A IT1195304B IT 1195304 B IT1195304 B IT 1195304B IT 25755/81 A IT25755/81 A IT 25755/81A IT 2575581 A IT2575581 A IT 2575581A IT 1195304 B IT1195304 B IT 1195304B
- Authority
- IT
- Italy
- Prior art keywords
- gem
- diamine
- preparation
- monoacylated derivatives
- monoacylated
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0212—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -N-C-N-C(=0)-, e.g. retro-inverso peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Peptides Or Proteins (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT25755/81A IT1195304B (it) | 1981-12-22 | 1981-12-22 | Metodo per la preparazione di gem-diammino derivati n-monoacilati |
| EP82201611A EP0084691A1 (en) | 1981-12-22 | 1982-12-16 | Method for preparing n-monoacylated gem-diamino derivatives |
| JP57224104A JPS58146538A (ja) | 1981-12-22 | 1982-12-22 | Ｎ−モノアシル化ジエム−ジアミノ誘導体の製法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT25755/81A IT1195304B (it) | 1981-12-22 | 1981-12-22 | Metodo per la preparazione di gem-diammino derivati n-monoacilati |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8125755A0 IT8125755A0 (it) | 1981-12-22 |
| IT1195304B true IT1195304B (it) | 1988-10-12 |
Family
ID=11217640
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT25755/81A IT1195304B (it) | 1981-12-22 | 1981-12-22 | Metodo per la preparazione di gem-diammino derivati n-monoacilati |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP0084691A1 (it) |
| JP (1) | JPS58146538A (it) |
| IT (1) | IT1195304B (it) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1188206B (it) * | 1985-11-28 | 1988-01-07 | Eniricerche Spa | Procedimento per la sintesi in fase solida di peptidi in cui almeno un legame ammidico e' retroinvertito |
| IT1228451B (it) * | 1989-02-22 | 1991-06-19 | Sclavo S P A Siena | Nuovi derivati diamminici geminali e loro impiego nelle sintesi di peptidi retro-inversi |
| US6610820B1 (en) * | 1999-10-12 | 2003-08-26 | University Of Lausanne | Cell-permeable peptide inhibitors of the JNK signal transduction pathway |
| US8183339B1 (en) | 1999-10-12 | 2012-05-22 | Xigen S.A. | Cell-permeable peptide inhibitors of the JNK signal transduction pathway |
| US20040082509A1 (en) | 1999-10-12 | 2004-04-29 | Christophe Bonny | Cell-permeable peptide inhibitors of the JNK signal transduction pathway |
| WO2007031098A1 (en) | 2005-09-12 | 2007-03-22 | Xigen S.A. | Cell-permeable peptide inhibitors of the jnk signal transduction pathway |
| US8080517B2 (en) | 2005-09-12 | 2011-12-20 | Xigen Sa | Cell-permeable peptide inhibitors of the JNK signal transduction pathway |
| WO2009143864A1 (en) | 2008-05-30 | 2009-12-03 | Xigen S.A. | Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of chronic or non-chronic inflammatory digestive diseases |
| WO2009143865A1 (en) | 2008-05-30 | 2009-12-03 | Xigen S.A. | Use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases |
| WO2010072228A1 (en) | 2008-12-22 | 2010-07-01 | Xigen S.A. | Novel transporter constructs and transporter cargo conjugate molecules |
| WO2011160653A1 (en) | 2010-06-21 | 2011-12-29 | Xigen S.A. | Novel jnk inhibitor molecules |
| AU2010362444B2 (en) | 2010-10-14 | 2015-08-06 | Xigen Inflammation Ltd. | Use of cell-permeable peptide inhibitors of the JNK signal transduction pathway for the treatment of chronic or non-chronic inflammatory eye diseases |
| WO2013091670A1 (en) | 2011-12-21 | 2013-06-27 | Xigen S.A. | Novel jnk inhibitor molecules for treatment of various diseases |
| KR20160023669A (ko) | 2013-06-26 | 2016-03-03 | 자이겐 인플라메이션 리미티드 | 다양한 질병의 치료를 위한 jnk 신호 전달 경로의 세포 투과성 펩타이드 억제자의 새로운 용도 |
| WO2015197097A1 (en) | 2014-06-26 | 2015-12-30 | Xigen Inflammation Ltd. | New use for jnk inhibitor molecules for treatment of various diseases |
| WO2014206427A1 (en) | 2013-06-26 | 2014-12-31 | Xigen Inflammation Ltd. | New use of cell-permeable peptide inhibitors of the jnk signal transduction pathway for the treatment of various diseases |
-
1981
- 1981-12-22 IT IT25755/81A patent/IT1195304B/it active
-
1982
- 1982-12-16 EP EP82201611A patent/EP0084691A1/en not_active Withdrawn
- 1982-12-22 JP JP57224104A patent/JPS58146538A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| EP0084691A1 (en) | 1983-08-03 |
| JPH0377178B2 (it) | 1991-12-09 |
| JPS58146538A (ja) | 1983-09-01 |
| IT8125755A0 (it) | 1981-12-22 |
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