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IT1189070B - Processo per la preparazione della l(-)-carnitina cloruro a partire da esteri 3,4-epossibutirrici - Google Patents

Processo per la preparazione della l(-)-carnitina cloruro a partire da esteri 3,4-epossibutirrici

Info

Publication number
IT1189070B
IT1189070B IT19763/86A IT1976386A IT1189070B IT 1189070 B IT1189070 B IT 1189070B IT 19763/86 A IT19763/86 A IT 19763/86A IT 1976386 A IT1976386 A IT 1976386A IT 1189070 B IT1189070 B IT 1189070B
Authority
IT
Italy
Prior art keywords
epoxybutyrrics
foreign
preparation
carnitine chloride
carnitine
Prior art date
Application number
IT19763/86A
Other languages
English (en)
Other versions
IT8619763A1 (it
IT8619763A0 (it
Inventor
Franco Francalanci
Marco Ricci
Pietro Cesti
Carlo Venturello
Original Assignee
Donegani Guido Ist
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Donegani Guido Ist filed Critical Donegani Guido Ist
Publication of IT8619763A0 publication Critical patent/IT8619763A0/it
Priority to IT19763/86A priority Critical patent/IT1189070B/it
Priority to ZA871691A priority patent/ZA871691B/xx
Priority to IL8781845A priority patent/IL81845A0/xx
Priority to JP62055460A priority patent/JPS62272983A/ja
Priority to AU69974/87A priority patent/AU585137B2/en
Priority to US07/025,351 priority patent/US4865771A/en
Priority to KR870002242A priority patent/KR870009026A/ko
Priority to ES198787103683T priority patent/ES2037018T3/es
Priority to BR8701180A priority patent/BR8701180A/pt
Priority to CA000532034A priority patent/CA1309683C/en
Priority to EP87103683A priority patent/EP0237080B1/en
Priority to DE8787103683T priority patent/DE3779455T2/de
Priority to AT87103683T priority patent/ATE76903T1/de
Publication of IT8619763A1 publication Critical patent/IT8619763A1/it
Application granted granted Critical
Publication of IT1189070B publication Critical patent/IT1189070B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/003Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
    • C12P41/005Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of carboxylic acid groups in the enantiomers or the inverse reaction
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
IT19763/86A 1986-03-14 1986-03-14 Processo per la preparazione della l(-)-carnitina cloruro a partire da esteri 3,4-epossibutirrici IT1189070B (it)

Priority Applications (13)

Application Number Priority Date Filing Date Title
IT19763/86A IT1189070B (it) 1986-03-14 1986-03-14 Processo per la preparazione della l(-)-carnitina cloruro a partire da esteri 3,4-epossibutirrici
ZA871691A ZA871691B (en) 1986-03-14 1987-03-09 Process for the preparation of l(-)-carnitine chloride starting from 3,4-epoxybutyric esters
IL8781845A IL81845A0 (en) 1986-03-14 1987-03-10 Preparation of l(-)-carnitine chloride from 3,4-epoxybutyric acid esters
JP62055460A JPS62272983A (ja) 1986-03-14 1987-03-12 3,4−エポキシ酪酸エステルから出発するl−(−)−カルニチンクロライドの製造方法
AU69974/87A AU585137B2 (en) 1986-03-14 1987-03-12 Process for the preparation of L(-) -carnitine chloride starting from 3,4-epoxybutyric esters
KR870002242A KR870009026A (ko) 1986-03-14 1987-03-13 3,4- 에폭시부티르 에스테르를 출발물질로 한 l(-)- 염화카니틴의 제조방법
US07/025,351 US4865771A (en) 1986-03-14 1987-03-13 Process for preparing L(-)-carnitine chloride from 3,4-epoxybutyric esters and novel intermediate compounds
ES198787103683T ES2037018T3 (es) 1986-03-14 1987-03-13 Procedimiento para la preparacion de cloruro de l(-)-carnitina a partir de esteres 3,4-epoxibutiricos.
BR8701180A BR8701180A (pt) 1986-03-14 1987-03-13 Processo para preparacao de cloreto de l(-)-carnitina e novos componentes
CA000532034A CA1309683C (en) 1986-03-14 1987-03-13 Process for preparing l(-)-carnitine chloride from 3, 4-epoxybutyric esters and novel intermediate compounds
EP87103683A EP0237080B1 (en) 1986-03-14 1987-03-13 Process for the preparation of l(-)-carnitine chloride starting from 3,4-epoxybutyric esters
DE8787103683T DE3779455T2 (de) 1986-03-14 1987-03-13 Verfahren zur herstellung von l(-)-carnitinchlorid, ausgehend von 3,4-epoxybuttersaeureestern.
AT87103683T ATE76903T1 (de) 1986-03-14 1987-03-13 Verfahren zur herstellung von l(-)carnitinchlorid, ausgehend von 3,4epoxybutters|ureestern.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT19763/86A IT1189070B (it) 1986-03-14 1986-03-14 Processo per la preparazione della l(-)-carnitina cloruro a partire da esteri 3,4-epossibutirrici

Publications (3)

Publication Number Publication Date
IT8619763A0 IT8619763A0 (it) 1986-03-14
IT8619763A1 IT8619763A1 (it) 1987-09-14
IT1189070B true IT1189070B (it) 1988-01-28

Family

ID=11161023

Family Applications (1)

Application Number Title Priority Date Filing Date
IT19763/86A IT1189070B (it) 1986-03-14 1986-03-14 Processo per la preparazione della l(-)-carnitina cloruro a partire da esteri 3,4-epossibutirrici

Country Status (13)

Country Link
US (1) US4865771A (it)
EP (1) EP0237080B1 (it)
JP (1) JPS62272983A (it)
KR (1) KR870009026A (it)
AT (1) ATE76903T1 (it)
AU (1) AU585137B2 (it)
BR (1) BR8701180A (it)
CA (1) CA1309683C (it)
DE (1) DE3779455T2 (it)
ES (1) ES2037018T3 (it)
IL (1) IL81845A0 (it)
IT (1) IT1189070B (it)
ZA (1) ZA871691B (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4923810A (en) * 1988-08-24 1990-05-08 Genzyme Corporation Resolution of glycidyl esters to high enantiomeric excess
US5244803A (en) * 1989-09-13 1993-09-14 Tanabe Seiyaku Co., Ltd. Process for preparing optically active 3-phenylglycidic acid esters
US5126268A (en) * 1990-03-30 1992-06-30 Eastman Kodak Company Alcohol-ester sparation by reaction with acetate
US5445963A (en) * 1990-03-30 1995-08-29 Eastman Chemical Company Alcohol-ester separation by recrystallization
US8334132B2 (en) 2006-11-09 2012-12-18 Mitsubishi Rayon Co., Ltd. Process for production of a betaine such as carnitine

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3135788A (en) * 1959-09-28 1964-06-02 Nihon Zoki Seiyaku Kabushikika Preparation of dl-carnitine hydrochloride from trimethylamine hydrochloride and epihalogenohydrin
US4259249A (en) * 1979-06-13 1981-03-31 The Procter & Gamble Company Preparation of hydroxyl zwitterionic compounds
IE56322B1 (en) * 1982-12-06 1991-06-19 Sigma Tau Ind Farmaceuti Process for preparing l-carnitine and chemical intermediates employed therein
JPS59192095A (ja) * 1983-04-13 1984-10-31 Ajinomoto Co Inc L−カルニチンの製造法
IT1184284B (it) * 1985-06-28 1987-10-22 Sigma Tau Ind Farmaceuti Procedimento per la preparazione di r(-)-norcarnitina terz-butil estere
IT1187681B (it) * 1985-07-05 1987-12-23 Montedison Spa Metodo per la preparazione di 3,4-epossibutirrati alchilici

Also Published As

Publication number Publication date
US4865771A (en) 1989-09-12
EP0237080A2 (en) 1987-09-16
IT8619763A1 (it) 1987-09-14
AU585137B2 (en) 1989-06-08
BR8701180A (pt) 1988-01-19
DE3779455T2 (de) 1993-01-28
IL81845A0 (en) 1987-10-20
ATE76903T1 (de) 1992-06-15
KR870009026A (ko) 1987-10-22
ZA871691B (en) 1987-10-28
CA1309683C (en) 1992-11-03
AU6997487A (en) 1987-09-17
EP0237080A3 (en) 1988-08-17
IT8619763A0 (it) 1986-03-14
EP0237080B1 (en) 1992-06-03
JPS62272983A (ja) 1987-11-27
DE3779455D1 (de) 1992-07-09
ES2037018T3 (es) 1993-06-16

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Legal Events

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19920228