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IT1162395B - AURONIC DERIVATIVES EQUIPPED WITH PHARMACOLOGICAL ACTIVITY AND PROCEDURE FOR THEIR PREPARATION - Google Patents

AURONIC DERIVATIVES EQUIPPED WITH PHARMACOLOGICAL ACTIVITY AND PROCEDURE FOR THEIR PREPARATION

Info

Publication number
IT1162395B
IT1162395B IT50245/79A IT5024579A IT1162395B IT 1162395 B IT1162395 B IT 1162395B IT 50245/79 A IT50245/79 A IT 50245/79A IT 5024579 A IT5024579 A IT 5024579A IT 1162395 B IT1162395 B IT 1162395B
Authority
IT
Italy
Prior art keywords
auronic
procedure
preparation
pharmacological activity
derivatives
Prior art date
Application number
IT50245/79A
Other languages
Italian (it)
Other versions
IT7950245A0 (en
Inventor
Stephen Richard Baker
William James Ross
William Boffey Jamieson
Original Assignee
Lilly Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Industries Ltd filed Critical Lilly Industries Ltd
Publication of IT7950245A0 publication Critical patent/IT7950245A0/en
Application granted granted Critical
Publication of IT1162395B publication Critical patent/IT1162395B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/32Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
    • C07C65/40Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups containing singly bound oxygen-containing groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/83Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/92Naphthofurans; Hydrogenated naphthofurans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/30Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
IT50245/79A 1978-09-13 1979-09-12 AURONIC DERIVATIVES EQUIPPED WITH PHARMACOLOGICAL ACTIVITY AND PROCEDURE FOR THEIR PREPARATION IT1162395B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7836705 1978-09-13

Publications (2)

Publication Number Publication Date
IT7950245A0 IT7950245A0 (en) 1979-09-12
IT1162395B true IT1162395B (en) 1987-03-25

Family

ID=10499649

Family Applications (1)

Application Number Title Priority Date Filing Date
IT50245/79A IT1162395B (en) 1978-09-13 1979-09-12 AURONIC DERIVATIVES EQUIPPED WITH PHARMACOLOGICAL ACTIVITY AND PROCEDURE FOR THEIR PREPARATION

Country Status (29)

Country Link
US (1) USRE32196E (en)
JP (1) JPS5540692A (en)
KR (1) KR830001919B1 (en)
AR (2) AR228020A1 (en)
AT (1) AT376968B (en)
AU (1) AU535369B2 (en)
BG (2) BG40315A3 (en)
CA (1) CA1202309A (en)
CH (1) CH644603A5 (en)
CS (1) CS214806B2 (en)
DD (1) DD146046A5 (en)
DK (1) DK382579A (en)
EG (1) EG14105A (en)
ES (1) ES484115A1 (en)
FI (1) FI792850A (en)
GR (1) GR71200B (en)
HU (1) HU181450B (en)
IE (1) IE48824B1 (en)
IL (1) IL58229A (en)
IT (1) IT1162395B (en)
MX (1) MX6232E (en)
NZ (1) NZ191556A (en)
PH (1) PH15712A (en)
PL (1) PL124296B1 (en)
PT (1) PT70170A (en)
SE (1) SE447382B (en)
SU (1) SU1138027A3 (en)
YU (1) YU222079A (en)
ZA (1) ZA794836B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6307070B1 (en) 1996-01-26 2001-10-23 Phytera, Inc. Substituted aurone derivatives
AU1709897A (en) * 1996-01-26 1997-08-20 Phytera, Inc. Antimicrobial aurone derivatives
CA2297753A1 (en) * 1997-07-25 1999-02-04 Phytera, Inc. Substituted aurone derivatives
WO1999012540A1 (en) * 1997-09-11 1999-03-18 Snow Brand Milk Products Co., Ltd. Remedies for hormone-dependent diseases
DE50104383D1 (en) * 2000-01-28 2004-12-09 Merck Patent Gmbh FORMULA CONTAINING BENZOFURANONE DERIVATIVES TO PROTECT AGAINST OXIDATIVE STRESS

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT277985B (en) * 1967-11-14 1970-01-12 Schering Ag Process for the preparation of new nitro-furan, -thiophene or -pyrrole derivatives
US4115567A (en) * 1973-12-27 1978-09-19 Carlo Erba S. P. A. 6-Carboxy-2-(2'-pyrazinyl)-chromones and esters thereof
US3975380A (en) * 1974-06-03 1976-08-17 Smithkline Corporation Substituted aurones
US4067993A (en) * 1975-09-24 1978-01-10 Riker Laboratories, Inc. Antimicrobial 2-nitro-3-phenylbenzofurancarboxylic acids
US4143145A (en) * 1977-01-12 1979-03-06 Carlo Erba S. P. A. Substituted 2-vinyl-chromones and process for their preparation
FR2396756A1 (en) * 1977-07-06 1979-02-02 Inst Nat Sante Rech Med NEW BENZYLIDENE-2-BENZOFURANNONES-3, THEIR OBTAINING AND THEIR APPLICATION AS MEDICINAL PRODUCTS
IT1093805B (en) * 1978-01-31 1985-07-26 Erba Carlo Spa DERIVATIVES OF 2H-BENZOFURAN-3-ONE AND PROCEDURE FOR THEIR PREPARATION
US4143055A (en) * 1978-03-27 1979-03-06 Gruppo Lepetit S.P.A. 2,4,6-trisubstituted-2,3-dihydro-benzofuran derivatives

Also Published As

Publication number Publication date
CH644603A5 (en) 1984-08-15
HU181450B (en) 1983-07-28
AU535369B2 (en) 1984-03-15
AR226210A1 (en) 1982-06-15
IE791729L (en) 1980-03-13
SE7907532L (en) 1980-03-14
PL124296B1 (en) 1983-01-31
MX6232E (en) 1985-01-14
DD146046A5 (en) 1981-01-21
ATA598079A (en) 1984-06-15
YU222079A (en) 1983-02-28
KR830001919B1 (en) 1983-09-23
ES484115A1 (en) 1980-04-16
GR71200B (en) 1983-04-11
AT376968B (en) 1985-01-25
AR228020A1 (en) 1983-01-14
IE48824B1 (en) 1985-05-29
FI792850A (en) 1980-03-14
USRE32196E (en) 1986-07-01
ZA794836B (en) 1981-03-25
JPS5540692A (en) 1980-03-22
SE447382B (en) 1986-11-10
IL58229A0 (en) 1979-12-30
PL218277A1 (en) 1980-07-14
CA1202309A (en) 1986-03-25
IL58229A (en) 1984-05-31
BG43187A3 (en) 1988-04-15
BG40315A3 (en) 1986-11-14
PH15712A (en) 1983-03-14
DK382579A (en) 1980-03-14
PT70170A (en) 1979-10-01
IT7950245A0 (en) 1979-09-12
EG14105A (en) 1983-03-31
NZ191556A (en) 1981-03-16
SU1138027A3 (en) 1985-01-30
CS214806B2 (en) 1982-06-25
AU5078079A (en) 1980-03-20

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