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IT1158152B - Procedimento per la preparazione di analoghi della somatostatina e prodotto ottenuto - Google Patents

Procedimento per la preparazione di analoghi della somatostatina e prodotto ottenuto

Info

Publication number
IT1158152B
IT1158152B IT52161/78A IT5216178A IT1158152B IT 1158152 B IT1158152 B IT 1158152B IT 52161/78 A IT52161/78 A IT 52161/78A IT 5216178 A IT5216178 A IT 5216178A IT 1158152 B IT1158152 B IT 1158152B
Authority
IT
Italy
Prior art keywords
procedure
preparation
product obtained
somatostatin analogs
somatostatin
Prior art date
Application number
IT52161/78A
Other languages
English (en)
Other versions
IT7852161A0 (it
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of IT7852161A0 publication Critical patent/IT7852161A0/it
Application granted granted Critical
Publication of IT1158152B publication Critical patent/IT1158152B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/16—Somatostatin; related peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IT52161/78A 1977-12-01 1978-12-01 Procedimento per la preparazione di analoghi della somatostatina e prodotto ottenuto IT1158152B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/856,364 US4139526A (en) 1977-12-01 1977-12-01 Somatostatin analogs

Publications (2)

Publication Number Publication Date
IT7852161A0 IT7852161A0 (it) 1978-12-01
IT1158152B true IT1158152B (it) 1987-02-18

Family

ID=25323425

Family Applications (1)

Application Number Title Priority Date Filing Date
IT52161/78A IT1158152B (it) 1977-12-01 1978-12-01 Procedimento per la preparazione di analoghi della somatostatina e prodotto ottenuto

Country Status (7)

Country Link
US (1) US4139526A (it)
EP (1) EP0002262B1 (it)
JP (1) JPS5495591A (it)
DE (1) DE2862319D1 (it)
DK (1) DK539478A (it)
IE (1) IE47683B1 (it)
IT (1) IT1158152B (it)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4191754A (en) * 1979-02-28 1980-03-04 Merck & Co., Inc. Bicyclic somatostatin analogs
US4190648A (en) * 1979-03-13 1980-02-26 Merck & Co., Inc. Peptides having somatostatin activity
EP0029579B1 (en) * 1979-11-27 1983-02-16 Sandoz Ag Polypeptides, processes for their production, pharmaceutical compositions comprising said polypeptides and their use
US4663435A (en) * 1982-12-06 1987-05-05 Merck & Co., Inc. Bridged cyclic hexapeptide somatostatin analogs
DE3379657D1 (en) * 1982-12-06 1989-05-24 Merck & Co Inc Dicyclic hexapeptides, processes for their preparation and pharmaceutical compositions containing them
DE3910667A1 (de) * 1988-04-11 1989-10-19 Sandoz Ag Peptidderivate
AU2003260306A1 (en) * 2002-07-17 2004-02-02 Boehringer Ingelheim Pharma Gmbh And Co. Kg Bicyclic oligopeptides
US7101848B2 (en) * 2002-10-08 2006-09-05 Boehringer Ingelheim Pharma Gmbh & Co. Kg Bicyclic oligopeptides

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2416048A1 (de) * 1974-04-03 1975-10-30 Hoechst Ag Neue peptide mit biologischer wirkung
DE2460469A1 (de) * 1974-12-20 1976-07-01 Hoechst Ag Neue peptide mit biologischer wirkung und verfahren zu ihrer herstellung
NL7607987A (nl) * 1975-08-08 1977-02-10 Merck & Co Inc Werkwijze voor het bereiden van peptiden.
CA1083143A (en) * 1976-01-02 1980-08-05 Nedumparambil A. Abraham Carba derivatives of somatostatin and process therefor
US3997517A (en) * 1976-01-30 1976-12-14 American Home Products Corporation Cyclic somatostatin disulfide analogues

Also Published As

Publication number Publication date
US4139526A (en) 1979-02-13
IE47683B1 (en) 1984-05-30
DE2862319D1 (en) 1983-10-20
IE782372L (en) 1979-06-01
IT7852161A0 (it) 1978-12-01
JPS6241240B2 (it) 1987-09-02
EP0002262B1 (en) 1983-09-14
DK539478A (da) 1979-06-02
JPS5495591A (en) 1979-07-28
EP0002262A1 (en) 1979-06-13

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