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IT1137459B - Prodesso per la preparazione di acido ursodeossicolico ad alta purezza - Google Patents

Prodesso per la preparazione di acido ursodeossicolico ad alta purezza

Info

Publication number
IT1137459B
IT1137459B IT21137/81A IT2113781A IT1137459B IT 1137459 B IT1137459 B IT 1137459B IT 21137/81 A IT21137/81 A IT 21137/81A IT 2113781 A IT2113781 A IT 2113781A IT 1137459 B IT1137459 B IT 1137459B
Authority
IT
Italy
Prior art keywords
acid
alpha
beta
ursodeoxicolic
preparation
Prior art date
Application number
IT21137/81A
Other languages
English (en)
Other versions
IT8121137A0 (it
Inventor
Antonio Bonaldi
Egidio Molinari
Original Assignee
Erregierre Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erregierre Spa filed Critical Erregierre Spa
Publication of IT8121137A0 publication Critical patent/IT8121137A0/it
Priority to IT21137/81A priority Critical patent/IT1137459B/it
Priority to US06/277,005 priority patent/US4379093A/en
Priority to EP82830083A priority patent/EP0063106B1/en
Priority to AT82830083T priority patent/ATE15207T1/de
Priority to IE803/82A priority patent/IE53198B1/en
Priority to DE8282830083T priority patent/DE3265743D1/de
Priority to NO821194A priority patent/NO162665C/no
Priority to ES511382A priority patent/ES8307835A1/es
Priority to CA000400880A priority patent/CA1185233A/en
Priority to YU802/82A priority patent/YU43074B/xx
Priority to DK164882A priority patent/DK164882A/da
Priority to PT74749A priority patent/PT74749B/pt
Priority to JP57061161A priority patent/JPS57203097A/ja
Priority to NO853328A priority patent/NO162562C/no
Application granted granted Critical
Publication of IT1137459B publication Critical patent/IT1137459B/it
Priority to JP61308927A priority patent/JPS62161798A/ja
Priority to JP2234631A priority patent/JPH03128392A/ja

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J51/00Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT21137/81A 1981-04-14 1981-04-14 Prodesso per la preparazione di acido ursodeossicolico ad alta purezza IT1137459B (it)

Priority Applications (16)

Application Number Priority Date Filing Date Title
IT21137/81A IT1137459B (it) 1981-04-14 1981-04-14 Prodesso per la preparazione di acido ursodeossicolico ad alta purezza
US06/277,005 US4379093A (en) 1981-04-14 1981-06-24 Process for preparing high purity ursodeoxycholic acid
EP82830083A EP0063106B1 (en) 1981-04-14 1982-04-05 Process for preparing high purity ursodeoxycholic acid
AT82830083T ATE15207T1 (de) 1981-04-14 1982-04-05 Verfahren zur herstellung von ursodeoxycholsaeure hoher reinheit.
IE803/82A IE53198B1 (en) 1981-04-14 1982-04-05 Process for preparing highly pure ursodeoxycholic acid
DE8282830083T DE3265743D1 (en) 1981-04-14 1982-04-05 Process for preparing high purity ursodeoxycholic acid
CA000400880A CA1185233A (en) 1981-04-14 1982-04-13 Process for preparing high purity ursodeoxycholic acid
ES511382A ES8307835A1 (es) 1981-04-14 1982-04-13 "un procedimiento para la preparacion de acido ursodeoxicolico de alta pureza".
NO821194A NO162665C (no) 1981-04-14 1982-04-13 Fremgangsmaate ved fremstilling av ursodeoxycholsyre av hoey renhet.
YU802/82A YU43074B (en) 1981-04-14 1982-04-13 Process for obtaining ursodeoxy cholic acid of high purity
DK164882A DK164882A (da) 1981-04-14 1982-04-13 Fremgangsmaade til fremstilling af 3-alfa-7-beta-dihydrocholansyre
PT74749A PT74749B (en) 1981-04-14 1982-04-14 Process for preparing high purity ursodeoxycholic acid
JP57061161A JPS57203097A (en) 1981-04-14 1982-04-14 Manufacture of high purity ulsodeoxycholic acid
NO853328A NO162562C (no) 1981-04-14 1985-08-23 3-alfa,-7beta-dihydroxy-12-keto-5beta-cholansyre og dennes tris-trimethylsilynderivat.
JP61308927A JPS62161798A (ja) 1981-04-14 1986-12-26 3α,7β−ジヒドロキシ−12−ケトコラン酸系化合物及びその製造方法
JP2234631A JPH03128392A (ja) 1981-04-14 1990-09-06 3α,7β―ジヒドロキシ―12―ケト―5β―コラン酸の精製方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21137/81A IT1137459B (it) 1981-04-14 1981-04-14 Prodesso per la preparazione di acido ursodeossicolico ad alta purezza

Publications (2)

Publication Number Publication Date
IT8121137A0 IT8121137A0 (it) 1981-04-14
IT1137459B true IT1137459B (it) 1986-09-10

Family

ID=11177288

Family Applications (1)

Application Number Title Priority Date Filing Date
IT21137/81A IT1137459B (it) 1981-04-14 1981-04-14 Prodesso per la preparazione di acido ursodeossicolico ad alta purezza

Country Status (13)

Country Link
US (1) US4379093A (it)
EP (1) EP0063106B1 (it)
JP (3) JPS57203097A (it)
AT (1) ATE15207T1 (it)
CA (1) CA1185233A (it)
DE (1) DE3265743D1 (it)
DK (1) DK164882A (it)
ES (1) ES8307835A1 (it)
IE (1) IE53198B1 (it)
IT (1) IT1137459B (it)
NO (1) NO162665C (it)
PT (1) PT74749B (it)
YU (1) YU43074B (it)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2511007A1 (fr) * 1981-08-07 1983-02-11 Roussel Uclaf Procede de preparation de l'acide ursodesoxycholique a partir de l'acide 3a, 7b, 12a-trihydroxycholanique et produit intermediaire utilises
IT1150756B (it) * 1982-04-02 1986-12-17 Zambon Spa Procedimento per preparare l'acido 3alfa, 7beta-diidrossi-5beta-colanico
FR2653127B1 (fr) * 1989-10-17 1994-12-09 Sanofi Sa Procede pour la preparation de 12-oxocholanates.
FR2653129B1 (fr) * 1989-10-17 1995-03-17 Sanofi Sa Procede pour la preparation de 7-oxocholanates.
DK0424232T3 (da) * 1989-10-17 1996-06-17 Sanofi Sa Fremgangsmåde til fremstilling af chenodesoxycholsyre
FR2653128B1 (fr) * 1989-10-17 1995-03-17 Sanofi Sa Procede pour la preparation de l'acide chenodesoxycholique.
JPH04152543A (ja) * 1990-10-16 1992-05-26 Agency Of Ind Science & Technol 自己検査機能を有する集積回路構造体、及びこれを用いた集積回路良品チップの選別方法
EP0548793A3 (en) * 1991-12-20 1995-11-02 Hoechst Ag Ethylenic-unsaturated bile acid derivatives, process for their production and preliminary processes therefor
DE4432708A1 (de) * 1994-09-14 1996-03-21 Hoechst Ag Modifizierte Gallensäuren, Verfahren zu ihrer Herstellung und ihre Verwendung
KR20010043558A (ko) * 1998-05-13 2001-05-25 한센 핀 베네드, 안네 제헤르, 웨이콥 마리안느 감수분열 조절 화합물
DK1392714T3 (da) 2001-03-12 2006-01-09 Intercept Pharmaceuticals Inc Steroider som agonister for FXR
WO2006007675A1 (en) * 2004-07-20 2006-01-26 Libbs Farmacêutica Ltda. Cholic acid and/or its derivatives for the reduction of localized fat in the human body
JP2015521621A (ja) * 2012-06-19 2015-07-30 インターセプト ファーマシューティカルズ, インコーポレイテッド オベチコール酸の調製、使用および固体形態
CN114195852A (zh) * 2021-12-28 2022-03-18 中山百灵生物技术股份有限公司 一种3β,7β-二羟基-5β-胆烷酸的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5012434A (it) * 1973-06-04 1975-02-08
JPS5233638A (en) * 1975-09-08 1977-03-14 Mitsui Petrochem Ind Ltd Process for preparation of aromatic alcohols
JPS5323302A (en) * 1976-08-18 1978-03-03 Mitsui Petrochem Ind Ltd Thermal cracking of hydrocarbons
JPS5536680A (en) * 1978-09-08 1980-03-14 Jidosha Kiki Co Ltd Flow control valve
FR2446293A1 (fr) * 1978-12-11 1980-08-08 Roussel Uclaf Procede de purification de l'acide chenodesoxycholique
FR2444048B1 (it) * 1978-12-15 1981-08-14 Roussel Uclaf
IT1165252B (it) * 1979-07-12 1987-04-22 Blasinachim Spa Procedimento di purificazione dell'acido ursodesossicolico attraverso nuovi derivati

Also Published As

Publication number Publication date
YU80282A (en) 1985-04-30
IT8121137A0 (it) 1981-04-14
IE820803L (en) 1982-10-14
IE53198B1 (en) 1988-08-31
DK164882A (da) 1982-10-15
EP0063106A1 (en) 1982-10-20
YU43074B (en) 1989-02-28
NO162665B (no) 1989-10-23
ATE15207T1 (de) 1985-09-15
ES511382A0 (es) 1983-09-01
JPH03128392A (ja) 1991-05-31
JPS62161798A (ja) 1987-07-17
ES8307835A1 (es) 1983-09-01
NO821194L (no) 1982-10-15
PT74749A (en) 1982-05-01
JPH0132238B2 (it) 1989-06-29
JPH045680B2 (it) 1992-02-03
PT74749B (en) 1983-11-08
NO162665C (no) 1990-01-31
US4379093A (en) 1983-04-05
DE3265743D1 (en) 1985-10-03
CA1185233A (en) 1985-04-09
JPS57203097A (en) 1982-12-13
JPS6320439B2 (it) 1988-04-27
EP0063106B1 (en) 1985-08-28

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19940428