IT1127384B - Derivati di acidi mercaptoacildii dropirazol carbossilici dotati di attivita' ipotensiva e procedimento per la loro preparazione - Google Patents

Derivati di acidi mercaptoacildii dropirazol carbossilici dotati di attivita' ipotensiva e procedimento per la loro preparazione

Info

Publication number: IT1127384B
Authority: IT; Italy
Prior art keywords: mercaptoacyldii; hypothensive; dropirazol; derivatives; activity
Prior art date: 1979-03-08

Application number

IT48062/80A

Other languages

English (en)

Other versions

IT8048062A0 (it

Inventor

George Charles Rovnyak

Original Assignee

Squibb & Sons Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-03-08

Filing date

1980-03-03

Publication date

1986-05-21

1980-03-03 Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc

1980-03-03 Publication of IT8048062A0 publication Critical patent/IT8048062A0/it

1986-05-21 Application granted granted Critical

1986-05-21 Publication of IT1127384B publication Critical patent/IT1127384B/it

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/06—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

IT48062/80A 1979-03-08 1980-03-03 Derivati di acidi mercaptoacildii dropirazol carbossilici dotati di attivita' ipotensiva e procedimento per la loro preparazione IT1127384B (it)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/018,548 US4211786A (en)	1979-03-08	1979-03-08	Mercaptoacyldihydropyrazole carboxylic acid derivatives

Publications (2)

Publication Number	Publication Date
IT8048062A0 IT8048062A0 (it)	1980-03-03
IT1127384B true IT1127384B (it)	1986-05-21

Family

ID=21788501

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IT48062/80A IT1127384B (it)	1979-03-08	1980-03-03	Derivati di acidi mercaptoacildii dropirazol carbossilici dotati di attivita' ipotensiva e procedimento per la loro preparazione

Country Status (16)

Country	Link
US (1)	US4211786A (it)
JP (1)	JPS55122766A (it)
AU (1)	AU534582B2 (it)
BE (1)	BE882133A (it)
CA (1)	CA1137497A (it)
CH (1)	CH645630A5 (it)
DE (1)	DE3008904A1 (it)
DK (1)	DK99980A (it)
FR (1)	FR2450820A1 (it)
GB (1)	GB2048850B (it)
IE (1)	IE49541B1 (it)
IT (1)	IT1127384B (it)
LU (1)	LU82223A1 (it)
NL (1)	NL8001349A (it)
SE (1)	SE450382B (it)
ZA (1)	ZA801016B (it)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA794723B (en) *	1978-09-11	1980-08-27	Univ Miami	Anti-hypertensive agents
US4288368A (en) *	1979-07-30	1981-09-08	E. R. Squibb & Sons, Inc.	Dithioacylproline derivatives
US4331806A (en) *	1979-07-30	1982-05-25	E. R. Squibb & Sons, Inc.	Dithioacyldihydropyrazole carboxylic acid derivatives
US4266065A (en) *	1980-04-14	1981-05-05	E. R. Squibb & Sons, Inc.	Mercaptoacyldihydropyrazole carboxylic acid derivatives
US4254267A (en) *	1979-10-25	1981-03-03	E. R. Squibb & Sons, Inc.	Mercaptoacyldihydropyrazole carboxylic acid derivatives
CA1156236A (en) *	1979-10-25	1983-11-01	George C. Rovnyak	Mercaptoacyldihydropyrazole carboxylic acid derivatives
US4692458A (en) *	1980-03-05	1987-09-08	University Of Miami	Anti-hypertensive agents
US4312990A (en) *	1980-09-11	1982-01-26	E. R. Squibb & Sons, Inc.	1-Mercaptoacyl-3-[(aminosulfonyl) phenyl]-4,5-dihydro-1H-pyrazole-5-carboxylic acid
US4371526A (en) *	1981-08-21	1983-02-01	E. R. Squibb & Sons, Inc.	Phosphinylalkanoyl substituted 4,5-dihydropyrazole-5-carboxylic acid derivatives and hypotensive method and composition
JPS58133376U (ja) *	1982-03-05	1983-09-08	吉原　靖人	バツテイング練習用バツト
US4470973A (en) *	1982-07-19	1984-09-11	E. R. Squibb & Sons, Inc.	Substituted peptide compounds
US4742067A (en) *	1982-07-22	1988-05-03	E. R. Squibb & Sons, Inc.	Acylalkylaminocarbonyl substituted amino and imino acid compounds
US4621092A (en) *	1982-07-22	1986-11-04	E. R. Squibb & Sons, Inc.	Substituted proline compounds, composition and method of use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4105776A (en) *	1976-06-21	1978-08-08	E. R. Squibb & Sons, Inc.	Proline derivatives and related compounds
US4046889A (en) *	1976-02-13	1977-09-06	E. R. Squibb & Sons, Inc.	Azetidine-2-carboxylic acid derivatives
US4053651A (en) *	1976-05-10	1977-10-11	E. R. Squibb & Sons, Inc.	Compounds and method for alleviating angiotensin related hypertension
ZA777062B (en) *	1976-12-03	1979-02-28	Squibb & Sons Inc	Derivatives of thiazolidinecarboxylic acids and related acids
US4129566A (en) *	1978-02-15	1978-12-12	E. R. Squibb & Sons, Inc.	Derivatives of dehydrocyclicimino acids

1979
- 1979-03-08 US US06/018,548 patent/US4211786A/en not_active Expired - Lifetime
1980
- 1980-02-15 CA CA000345726A patent/CA1137497A/en not_active Expired
- 1980-02-22 ZA ZA00801016A patent/ZA801016B/xx unknown
- 1980-02-22 AU AU55822/80A patent/AU534582B2/en not_active Ceased
- 1980-03-03 IT IT48062/80A patent/IT1127384B/it active
- 1980-03-05 LU LU82223A patent/LU82223A1/de unknown
- 1980-03-06 IE IE449/80A patent/IE49541B1/en not_active IP Right Cessation
- 1980-03-06 CH CH177180A patent/CH645630A5/de not_active IP Right Cessation
- 1980-03-06 NL NL8001349A patent/NL8001349A/nl not_active Application Discontinuation
- 1980-03-07 GB GB8007914A patent/GB2048850B/en not_active Expired
- 1980-03-07 DE DE19803008904 patent/DE3008904A1/de not_active Ceased
- 1980-03-07 SE SE8001818A patent/SE450382B/sv not_active IP Right Cessation
- 1980-03-07 FR FR8005217A patent/FR2450820A1/fr active Granted
- 1980-03-07 BE BE0/199718A patent/BE882133A/fr not_active IP Right Cessation
- 1980-03-07 DK DK99980A patent/DK99980A/da not_active Application Discontinuation
- 1980-03-08 JP JP2971480A patent/JPS55122766A/ja active Granted

Also Published As

Publication number	Publication date
SE450382B (sv)	1987-06-22
AU5582280A (en)	1980-09-11
LU82223A1 (de)	1980-09-24
NL8001349A (nl)	1980-09-10
CA1137497A (en)	1982-12-14
DE3008904A1 (de)	1980-09-18
ZA801016B (en)	1981-02-25
IE800449L (en)	1980-09-08
JPH0141628B2 (it)	1989-09-06
IE49541B1 (en)	1985-10-30
FR2450820A1 (fr)	1980-10-03
BE882133A (fr)	1980-09-08
IT8048062A0 (it)	1980-03-03
US4211786A (en)	1980-07-08
AU534582B2 (en)	1984-02-09
CH645630A5 (de)	1984-10-15
JPS55122766A (en)	1980-09-20
GB2048850B (en)	1983-04-27
GB2048850A (en)	1980-12-17
SE8001818L (sv)	1980-09-09
DK99980A (da)	1980-09-09
FR2450820B1 (it)	1983-04-22

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Legal Events

Date	Code	Title	Description
1999-10-27	TA	Fee payment date (situation as of event date), data collected since 19931001	Effective date: 19930315