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IT1110603B - Derivati d'ammidi e d'idrazidi d'acidi grassi a lunga catena, loro preparazione e medicamenti contenenti questi derivati - Google Patents

Derivati d'ammidi e d'idrazidi d'acidi grassi a lunga catena, loro preparazione e medicamenti contenenti questi derivati

Info

Publication number
IT1110603B
IT1110603B IT19059/79A IT1905979A IT1110603B IT 1110603 B IT1110603 B IT 1110603B IT 19059/79 A IT19059/79 A IT 19059/79A IT 1905979 A IT1905979 A IT 1905979A IT 1110603 B IT1110603 B IT 1110603B
Authority
IT
Italy
Prior art keywords
derivatives
amides
preparation
fatty acids
long chain
Prior art date
Application number
IT19059/79A
Other languages
English (en)
Italian (it)
Other versions
IT7919059A0 (it
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/881,780 external-priority patent/US4229463A/en
Priority claimed from US05/891,298 external-priority patent/US4194002A/en
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IT7919059A0 publication Critical patent/IT7919059A0/it
Application granted granted Critical
Publication of IT1110603B publication Critical patent/IT1110603B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
    • C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
    • C04B22/00—Use of inorganic materials as active ingredients for mortars, concrete or artificial stone, e.g. accelerators, shrinkage compensating agents
    • C04B22/0013—Boron compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C243/00—Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes
    • C07C243/24—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids
    • C07C243/26—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C243/28—Hydrazines having nitrogen atoms of hydrazine groups acylated by carboxylic acids with acylating carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of a saturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Ceramic Engineering (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials Engineering (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Structural Engineering (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT19059/79A 1978-01-09 1979-01-04 Derivati d'ammidi e d'idrazidi d'acidi grassi a lunga catena, loro preparazione e medicamenti contenenti questi derivati IT1110603B (it)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US86782478A 1978-01-09 1978-01-09
US86781378A 1978-01-09 1978-01-09
US87283678A 1978-01-27 1978-01-27
US88178178A 1978-02-27 1978-02-27
US05/881,780 US4229463A (en) 1978-02-27 1978-02-27 Unsaturated fatty acid hydrazides
US05/891,298 US4194002A (en) 1978-03-29 1978-03-29 Cholesterol ester-reducing amides of hexahydroindolinols

Publications (2)

Publication Number Publication Date
IT7919059A0 IT7919059A0 (it) 1979-01-04
IT1110603B true IT1110603B (it) 1985-12-23

Family

ID=27560330

Family Applications (1)

Application Number Title Priority Date Filing Date
IT19059/79A IT1110603B (it) 1978-01-09 1979-01-04 Derivati d'ammidi e d'idrazidi d'acidi grassi a lunga catena, loro preparazione e medicamenti contenenti questi derivati

Country Status (20)

Country Link
JP (1) JPS54109930A (sv)
AU (1) AU529328B2 (sv)
CA (1) CA1101871A (sv)
CH (1) CH644842A5 (sv)
CY (1) CY1294A (sv)
DE (1) DE2856856A1 (sv)
DK (1) DK3079A (sv)
FI (1) FI790025A (sv)
FR (1) FR2416885A1 (sv)
GB (1) GB2012261B (sv)
HK (1) HK80985A (sv)
IE (1) IE48077B1 (sv)
IL (1) IL56393A (sv)
IT (1) IT1110603B (sv)
KE (1) KE3546A (sv)
MY (1) MY8500133A (sv)
NZ (1) NZ189331A (sv)
PT (1) PT69052A (sv)
SE (1) SE446093B (sv)
SG (1) SG42985G (sv)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2937175A1 (de) * 1978-09-18 1980-03-27 Sandoz Ag Sekundaere amide von 2-alkynoylsaeuren, deren herstellung und deren pharmazeutischen zusammensetzungen
US4297349A (en) 1980-04-15 1981-10-27 Sandoz, Inc. Silicon-bearing carboxylic acids and amides
US4722927A (en) * 1986-04-28 1988-02-02 Warner-Lambert Company Pyrimidine amides of oleic or linoleic acid, composition containing them and their use as inhibitors of acyl-CoA cholesterol acyltransferase
FR2633617B1 (fr) * 1988-07-04 1991-02-08 Adir Nouveaux derives du benzocycloheptene, leur procede de preparation et les compositions pharmaceutiques les renfermant
US5290814A (en) * 1988-11-21 1994-03-01 Burroughs Wellcome Co. Anti-atherosclerotic diaryl compounds
JP5607025B2 (ja) * 2008-04-21 2014-10-15 シグナム バイオサイエンシーズ， インコーポレイテッド 化合物、組成物およびそれらを作製する方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1814334B2 (de) * 1967-12-21 1973-04-19 Sumitomo Chemical Co Ltd , Osaka (Japan) Fettsaeureamide und diese verbindungen enthaltende arzneimittel
FR2000945A1 (sv) * 1968-01-30 1969-09-19 Sumitomo Chemical Co
JPS5835505B2 (ja) * 1976-01-09 1983-08-03 エーザイ株式会社 Ｎ−（α−メチル−ベンジル）−脂肪酸アミド

Also Published As

Publication number Publication date
AU4323379A (en) 1979-07-19
IE790031L (en) 1979-07-09
JPS6323987B2 (sv) 1988-05-18
GB2012261B (en) 1982-12-22
FR2416885B1 (sv) 1983-04-22
HK80985A (en) 1985-10-25
SE7900142L (sv) 1979-07-10
IL56393A (en) 1982-08-31
CY1294A (en) 1985-10-18
JPS54109930A (en) 1979-08-29
IT7919059A0 (it) 1979-01-04
FI790025A (fi) 1979-07-10
IE48077B1 (en) 1984-09-19
SE446093B (sv) 1986-08-11
IL56393A0 (en) 1979-03-12
DK3079A (da) 1979-07-10
AU529328B2 (en) 1983-06-02
CH644842A5 (de) 1984-08-31
PT69052A (fr) 1979-02-01
MY8500133A (en) 1985-12-31
KE3546A (en) 1985-07-19
DE2856856A1 (de) 1979-07-12
NZ189331A (en) 1981-07-13
CA1101871A (en) 1981-05-26
FR2416885A1 (fr) 1979-09-07
GB2012261A (en) 1979-07-25
SG42985G (en) 1985-12-13

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