[go: up one dir, main page]

IN2014MN00880A - - Google Patents

Info

Publication number
IN2014MN00880A
IN2014MN00880A IN880MUN2014A IN2014MN00880A IN 2014MN00880 A IN2014MN00880 A IN 2014MN00880A IN 880MUN2014 A IN880MUN2014 A IN 880MUN2014A IN 2014MN00880 A IN2014MN00880 A IN 2014MN00880A
Authority
IN
India
Prior art keywords
composition
degrees celsius
buffer
viscosity
mpas
Prior art date
Application number
Inventor
Evan C Unger
Jennifer L Johnson
Original Assignee
Nuvox Pharma L L C
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nuvox Pharma L L C filed Critical Nuvox Pharma L L C
Publication of IN2014MN00880A publication Critical patent/IN2014MN00880A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/02—Halogenated hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/02—Halogenated hydrocarbons
    • A61K31/025—Halogenated hydrocarbons carbocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/02—Halogenated hydrocarbons
    • A61K31/025—Halogenated hydrocarbons carbocyclic
    • A61K31/03—Halogenated hydrocarbons carbocyclic aromatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7016—Disaccharides, e.g. lactose, lactulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

An oxygen therapeutic composition comprising a perfluorocarbon material a viscosity modifier a buffer wherein the buffer stabilizes a pH of the composition at between about 6.5 to about 7.5 and wherein the composition comprises a viscosity of about 2.0 to about 3.5 mPas and wherein the fluorocarbon has a boiling point of about 4 degrees Celsius to about 60 degrees Celsius.
IN880MUN2014 2011-10-13 2012-10-15 IN2014MN00880A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13/273,115 US8822549B2 (en) 2011-10-13 2011-10-13 Buffered oxygen therapeutic
PCT/US2012/060284 WO2013056246A1 (en) 2011-10-13 2012-10-15 Buffered oxygen therapeutic

Publications (1)

Publication Number Publication Date
IN2014MN00880A true IN2014MN00880A (en) 2015-04-17

Family

ID=48082584

Family Applications (1)

Application Number Title Priority Date Filing Date
IN880MUN2014 IN2014MN00880A (en) 2011-10-13 2012-10-15

Country Status (8)

Country Link
US (1) US8822549B2 (en)
EP (1) EP2766001B1 (en)
JP (3) JP6117220B2 (en)
CN (2) CN108685882A (en)
AU (1) AU2012323862B2 (en)
CA (2) CA2851522C (en)
IN (1) IN2014MN00880A (en)
WO (1) WO2013056246A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9700523B2 (en) * 2011-10-13 2017-07-11 Nuvox Pharma Llc Buffered oxygen therapeutic
US8822549B2 (en) * 2011-10-13 2014-09-02 Jennifer L. Johnson Buffered oxygen therapeutic
WO2015034940A1 (en) * 2013-09-03 2015-03-12 Arizona Board Of Regents On Behalf Of The University Of Arizona Cardioprotectant to reduce damage from heart attack
EP3113766B1 (en) * 2014-03-05 2021-04-07 Evan C. Unger Fractionated radiotherapy and chemotherapy with an oxygen therapeutic
WO2017112614A1 (en) * 2015-12-21 2017-06-29 Nuvox Pharma Llc Compositions of fluorocarbon nanoemulsion, and methods of preparation and use thereof
CN115814325B (en) * 2022-11-23 2024-04-19 浙江工业大学 A fluorine-containing fire extinguishing agent composition

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4423077A (en) * 1982-07-27 1983-12-27 The University Of Pennsylvania Perfluorochemical emulsion artificial blood
US5585112A (en) * 1989-12-22 1996-12-17 Imarx Pharmaceutical Corp. Method of preparing gas and gaseous precursor-filled microspheres
US5656211A (en) * 1989-12-22 1997-08-12 Imarx Pharmaceutical Corp. Apparatus and method for making gas-filled vesicles of optimal size
US5114932A (en) * 1990-11-30 1992-05-19 Runge Thomas M Hyperosmolar oxyreplete hemosubstitute
US5196199A (en) * 1990-12-14 1993-03-23 Fuisz Technologies Ltd. Hydrophilic form of perfluoro compounds and method of manufacture
US5628930A (en) 1992-10-27 1997-05-13 Alliance Pharmaceutical Corp. Stabilization of fluorocarbon emulsions
US5595687A (en) 1992-10-30 1997-01-21 Thomas Jefferson University Emulsion stability
DE69427185T2 (en) 1993-01-25 2001-12-06 Sonus Pharmaceutical, Inc. Phase-pen colloids for use as ultrasound contrast agents
US7083572B2 (en) * 1993-11-30 2006-08-01 Bristol-Myers Squibb Medical Imaging, Inc. Therapeutic delivery systems
US20030032879A1 (en) 1997-07-07 2003-02-13 Steven Quay Microbubble formation using ultrasound
US7357937B2 (en) * 2002-09-24 2008-04-15 Therox, Inc. Perfluorocarbon emulsions with non-fluorinated surfactants
EP2419392A4 (en) 2009-04-15 2013-02-27 Oxygen Biotherapeutics Inc EMULSIONS OF PERFLUOROCARBONES
US8822549B2 (en) * 2011-10-13 2014-09-02 Jennifer L. Johnson Buffered oxygen therapeutic

Also Published As

Publication number Publication date
CN104039317A (en) 2014-09-10
CN108685882A (en) 2018-10-23
CA2851522C (en) 2019-11-26
AU2012323862B2 (en) 2015-07-09
JP6479870B2 (en) 2019-03-06
EP2766001A1 (en) 2014-08-20
JP2019089816A (en) 2019-06-13
US20130096204A1 (en) 2013-04-18
EP2766001B1 (en) 2024-05-15
JP6117220B2 (en) 2017-04-19
WO2013056246A1 (en) 2013-04-18
CN104039317B (en) 2018-05-25
JP2014528487A (en) 2014-10-27
JP2017132789A (en) 2017-08-03
US8822549B2 (en) 2014-09-02
EP2766001C0 (en) 2024-05-15
AU2012323862A1 (en) 2014-05-29
EP2766001A4 (en) 2015-06-10
JP6789328B2 (en) 2020-11-25
CA2851522A1 (en) 2013-04-18
CA3057480C (en) 2021-07-20
CA3057480A1 (en) 2013-04-18

Similar Documents

Publication Publication Date Title
CY1120646T1 (en) ORIGINAL CELLS OF INTERMEDERAL ORIGIN
PH12015501720A1 (en) Modulators of methyl modifying enzymes, compositions and uses thereof
MY178142A (en) Anti-phf-tau antibodies and their uses
MX339059B (en) Personal care compositions.
PH12013502121A1 (en) Fusion proteins and combiantion vaccines comprising haemophilus influenzae preotein e and pilin a
MY186864A (en) Fusion immunomodulatory proteins and methods for making same
MX2012007710A (en) Alpha-amylases.
MX347165B (en) Effervescent composition in solid form for use in vaginal applications for the treatment of vaginal infections.
IN2014DN08721A (en)
IN2014MN00880A (en)
IN2014DN10712A (en)
MY156851A (en) Azeotropic and azeotrope-like compositions of methyl perfluoroheptene ethers and trans-1,2-dichloroethylene and uses thereof
IN2014DN10710A (en)
EP3039137A4 (en) Engineered primate cystine/cysteine degrading enzymes as antineogenic agents
MX2015016406A (en) Wood coating composition.
AU2016335217A8 (en) Antigen receptors and uses thereof
IN2014DN06104A (en)
MX2019003619A (en) Bromocriptine formulations.
MX356178B (en) Use of sugars in a stabilization matrix and solid compositions.
MX354368B (en) Gel-wipe for personal care and household cleansing.
MY165500A (en) Use of methylhydroxyethyl cellulose as cement additive
MX2014005854A (en) METHOD FOR PRODUCING A SLIDING BEARING COMPRISING A CuNi2Si, CuFe2P OR CuSnX COMPOUND.
WO2015027160A3 (en) Allosteric modulators of the cannibinoid 1 receptor
IN2012DN06607A (en)
GB201106162D0 (en) Combination vaccine