IN2014DN08198A - - Google Patents
Info
- Publication number
- IN2014DN08198A IN2014DN08198A IN8198DEN2014A IN2014DN08198A IN 2014DN08198 A IN2014DN08198 A IN 2014DN08198A IN 8198DEN2014 A IN8198DEN2014 A IN 8198DEN2014A IN 2014DN08198 A IN2014DN08198 A IN 2014DN08198A
- Authority
- IN
- India
- Prior art keywords
- crystal form
- compounds
- parameters
- androsta
- triol
- Prior art date
Links
- 239000013078 crystal Substances 0.000 abstract 6
- 150000001875 compounds Chemical class 0.000 abstract 2
- 238000002844 melting Methods 0.000 abstract 1
- 230000008018 melting Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000004526 pharmaceutical effect Effects 0.000 abstract 1
- 238000000634 powder X-ray diffraction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0007—Androstane derivatives not substituted in position 17
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Abstract
Disclosed are four compounds of crystal form of androsta-¾5a,6p-triol (YC-6 for short) (YC-6 of A crystal form, YC-6 of B crystal form, YC-6 of C crystal form, YC-6 of D crystal form) and a method for preparing same. The four compounds of crystal form are characterized b y remarkable differences in parameters such as lattice parameters, 2Θ and intensity of X-ray powder diffraction, melting point, etc. Study on the polymorphism is significant for further researching the pharmaceutical effect, bioavailability and stability thereof.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210060611.6A CN102617685B (en) | 2012-03-08 | 2012-03-08 | Crystal form compounds of androstane-3beta,5alpha,6beta-triol and preparation method thereof |
| PCT/CN2012/073854 WO2013131305A1 (en) | 2012-03-08 | 2012-04-11 | Compound of crystal form of androsta-3β,5α,6β-triol and method for preparing same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2014DN08198A true IN2014DN08198A (en) | 2015-05-01 |
Family
ID=46557937
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN8198DEN2014 IN2014DN08198A (en) | 2012-03-08 | 2012-04-11 |
Country Status (13)
| Country | Link |
|---|---|
| US (3) | US9688716B2 (en) |
| EP (2) | EP3112374A1 (en) |
| JP (1) | JP2015511587A (en) |
| KR (1) | KR20150002653A (en) |
| CN (4) | CN102617685B (en) |
| AU (1) | AU2012372640B2 (en) |
| CA (2) | CA2866398C (en) |
| IL (1) | IL234492A (en) |
| IN (1) | IN2014DN08198A (en) |
| RU (1) | RU2608894C2 (en) |
| SG (1) | SG11201405376TA (en) |
| TW (1) | TW201336861A (en) |
| WO (1) | WO2013131305A1 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6470171B2 (en) | 2012-05-07 | 2019-02-13 | ザ プロクター アンド ギャンブル カンパニー | Flexible container |
| CN109985048B (en) * | 2017-12-29 | 2021-06-29 | 广州市赛普特医药科技股份有限公司 | 2 beta, 3 alpha, 5 alpha-trihydroxyandrost-6-one for the treatment of inflammatory reactions |
| US11532903B2 (en) * | 2021-04-01 | 2022-12-20 | Ideal Industries, Inc. | Universal electrical connector |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2191576A (en) | 1936-11-21 | 1940-02-27 | Soc Of Chemical Ind | 3,5,6-trihydroxy androstane and pregnane compounds |
| US2191578A (en) | 1939-07-24 | 1940-02-27 | Crosley Corp | Ice-cream tray |
| DE3265852D1 (en) * | 1981-09-21 | 1985-10-03 | Schering Ag | 3-beta,7-beta,15-alpha-trihydroxy-5-androsten-17-one, its 3,15-dipivalate, and its preparation |
| US6046185A (en) * | 1996-07-11 | 2000-04-04 | Inflazyme Pharmaceuticals Ltd. | 6,7-oxygenated steroids and uses related thereto |
| CN101884638B (en) * | 2010-07-09 | 2011-11-09 | 中山大学 | Application of 5alpha-androstane-3beta,5,6beta-triol in preparing neuro-protective medicaments |
| CN101961311B (en) * | 2010-09-21 | 2012-11-21 | 中山大学 | 5alpha-androstane (alkyl)-3beta,5,6beta-triol injection and preparation method thereof |
| CN102180928B (en) * | 2011-03-15 | 2013-01-16 | 广州市赛普特医药科技有限公司 | 3-beta,5-alpha,6-beta-trihydroxy steroid compounds, and synthesis method and application thereof |
-
2012
- 2012-03-08 CN CN201210060611.6A patent/CN102617685B/en active Active
- 2012-03-08 CN CN201310392426.1A patent/CN103626817B/en active Active
- 2012-03-08 CN CN201310393373.5A patent/CN103626819B/en active Active
- 2012-03-08 CN CN201310393026.2A patent/CN103626818B/en active Active
- 2012-04-11 AU AU2012372640A patent/AU2012372640B2/en active Active
- 2012-04-11 EP EP16184231.5A patent/EP3112374A1/en not_active Ceased
- 2012-04-11 RU RU2014136891A patent/RU2608894C2/en active
- 2012-04-11 WO PCT/CN2012/073854 patent/WO2013131305A1/en active Application Filing
- 2012-04-11 CA CA2866398A patent/CA2866398C/en active Active
- 2012-04-11 SG SG11201405376TA patent/SG11201405376TA/en unknown
- 2012-04-11 CA CA2909998A patent/CA2909998A1/en not_active Abandoned
- 2012-04-11 IN IN8198DEN2014 patent/IN2014DN08198A/en unknown
- 2012-04-11 JP JP2014560211A patent/JP2015511587A/en active Pending
- 2012-04-11 US US14/383,405 patent/US9688716B2/en active Active
- 2012-04-11 EP EP12870566.2A patent/EP2889303A4/en not_active Withdrawn
- 2012-04-11 KR KR1020147028362A patent/KR20150002653A/en not_active Ceased
-
2013
- 2013-03-07 TW TW102108093A patent/TW201336861A/en unknown
-
2014
- 2014-09-07 IL IL234492A patent/IL234492A/en active IP Right Grant
-
2017
- 2017-05-08 US US15/589,228 patent/US9944672B2/en active Active
- 2017-05-08 US US15/589,268 patent/US9944673B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2012372640B2 (en) | 2015-07-09 |
| AU2012372640A1 (en) | 2014-09-25 |
| US20150045566A1 (en) | 2015-02-12 |
| CN103626819B (en) | 2016-01-20 |
| IL234492A (en) | 2017-02-28 |
| CN103626817B (en) | 2016-01-20 |
| US9688716B2 (en) | 2017-06-27 |
| CA2909998A1 (en) | 2013-09-12 |
| CN103626818B (en) | 2016-03-30 |
| CN102617685A (en) | 2012-08-01 |
| US9944673B2 (en) | 2018-04-17 |
| SG11201405376TA (en) | 2014-11-27 |
| WO2013131305A1 (en) | 2013-09-12 |
| EP2889303A4 (en) | 2016-02-17 |
| KR20150002653A (en) | 2015-01-07 |
| US9944672B2 (en) | 2018-04-17 |
| CN102617685B (en) | 2014-01-22 |
| CA2866398A1 (en) | 2013-09-12 |
| US20170305957A1 (en) | 2017-10-26 |
| CN103626819A (en) | 2014-03-12 |
| CA2866398C (en) | 2016-06-28 |
| RU2014136891A (en) | 2016-05-10 |
| EP3112374A1 (en) | 2017-01-04 |
| EP2889303A1 (en) | 2015-07-01 |
| TW201336861A (en) | 2013-09-16 |
| US20170305958A1 (en) | 2017-10-26 |
| CN103626818A (en) | 2014-03-12 |
| JP2015511587A (en) | 2015-04-20 |
| CN103626817A (en) | 2014-03-12 |
| RU2608894C2 (en) | 2017-01-26 |
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