[go: up one dir, main page]

IN2014DN07481A - - Google Patents

Info

Publication number
IN2014DN07481A
IN2014DN07481A IN7481DEN2014A IN2014DN07481A IN 2014DN07481 A IN2014DN07481 A IN 2014DN07481A IN 7481DEN2014 A IN7481DEN2014 A IN 7481DEN2014A IN 2014DN07481 A IN2014DN07481 A IN 2014DN07481A
Authority
IN
India
Prior art keywords
derivatives
nystatin
complexes
formula
pharmaceutical compositions
Prior art date
Application number
Inventor
Edward Borowski
Natalia Salewska
Majewska Joanna Boros
Maria Milewska
Malgorzata Wysocka
Slawomir Milewski
Andrzej Skladanowski
Adam Treder
Ewa Sadowska
Izabela Lacka
Original Assignee
Blirt S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Blirt S A filed Critical Blirt S A
Publication of IN2014DN07481A publication Critical patent/IN2014DN07481A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The invention provides semisynthetic derivatives of Nystatin Ai, water soluble salts and complexes, pharmaceutical compositions and plant protection products comprising the derivatives and their use as antifungal antibiotics (Formula 1a).
IN7481DEN2014 2012-03-09 2013-03-07 IN2014DN07481A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PL39839012 2012-03-09
PCT/EP2013/054621 WO2013132014A1 (en) 2012-03-09 2013-03-07 Semisynthetic derivatives of nystatin a1

Publications (1)

Publication Number Publication Date
IN2014DN07481A true IN2014DN07481A (en) 2015-04-24

Family

ID=47827245

Family Applications (1)

Application Number Title Priority Date Filing Date
IN7481DEN2014 IN2014DN07481A (en) 2012-03-09 2013-03-07

Country Status (4)

Country Link
US (1) US9447136B2 (en)
EP (1) EP2852601A1 (en)
IN (1) IN2014DN07481A (en)
WO (1) WO2013132014A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016014779A1 (en) * 2014-07-23 2016-01-28 The Board Of Trustees Of The University Of Illinois Antifungal polyene macrolide derivatives with reduced mammalian toxicity
CH713538B1 (en) 2017-03-02 2020-12-30 Guebelin Gem Lab Ltd Procedure for making a gemstone traceable.
SG11202107818VA (en) 2019-01-31 2021-08-30 Sigma Aldrich Co Llc Antifungal agents with improved water solubility

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3244590A (en) 1960-12-23 1966-04-05 Rutgers Res And Educational Fo Polyenic compounds and procedures related thereto
GB1359473A (en) 1970-11-03 1974-07-10 Prodotti Antibiotici Spa Polyenic antibiotic
PL82224B1 (en) 1971-08-13 1975-10-31
FI60877C (en) 1971-08-13 1982-04-13 Politechnika Gdanska PROTECTION OF THERAPEUTIC ACTIVITIES OF THERAPEUTIC ACTIVITIES WITH A DISPENSABLE POLYENMACROLIDANTIBIOTICS-N-GLYCOSYL DERIVATIVES
US4195172A (en) * 1976-04-22 1980-03-25 Politechnika Gdanska Salts of N-glycosyl derivatives of polyene macrolides, especially N-methylglucamine salts as well as the method of their preparation
PL100966B1 (en) 1976-04-22 1978-11-30 METHOD OF OBTAINING N-GLYCOSYL DERIVATIVES OF POLYENUM MACROLIDES AND THEIR SALT, ESPECIALLY N-METHYL GLUCAMINE SALT
PL199213A1 (en) 1976-06-30 1978-02-27 Bergwerksverband Gmbh METHOD OF PRESSURE OF HYDROGEN SULFUR FROM HOT GASES
DE2706156C3 (en) * 1977-02-14 1981-08-20 Vsesojuznyj naučno-issledovatel'skij technologičeskij institut antibiotikov i fermentov medicinskogo naznačenija, Leningrad N, N, N-trimethyl derivatives of amphoteric, antifungal polyene antibiotics and processes for their preparation
US4144328A (en) 1977-02-28 1979-03-13 Vainshtein Viktor A N,N,N-Trimethyl derivatives of polyene amphoteric antibiotics, process of producing same and pharmaceutical composition
PL122884B1 (en) 1978-07-19 1982-08-31 Politechnika Gdanska Method of manufacture of quaternary trimethylammonium salts of inorganic derivatives of polyene macrolides
US4272525A (en) 1978-10-23 1981-06-09 Schering Corporation Derivatives of polyene macrolide antibiotics containing an amino sugar moiety, process for the preparation thereof, and pharmaceutical compositions containing them
PL120111B1 (en) 1978-11-10 1982-02-27 Politechnika Gdanska Process for preparing novel n-substituted derivatives of antibiotics from the group of polyenic macrolydestibiotikov iz gruppy polienovykh makrolidov
PL120035B1 (en) 1978-12-20 1982-02-27 Politechnika Gdanska Process for preparing novel methyl esters of n-substituted derivatives of antibiotics from the group of polyenic macrolydesykh proizvodnykh antibiotikov iz gruppy polienovykh makrolidov
ZA807892B (en) 1979-12-24 1981-12-30 Dumex Ltd As Water soluble guanidine derivatives of polyene marcrolides and the esters thereof
PL138831B1 (en) 1983-11-16 1986-11-29 Politechnika Gdanska Process for preparing l-aspartates of 3-/n,n-dimethylamino/-propylamides of antibiotics from polyene macrolids group
PL142848B1 (en) 1984-10-29 1987-12-31 Politechnika Gdanska Method of obtaining derivatives of n-/n,n-dimethylaminoacyl methyl esters and 3-/n,n-dimethylamino/-propylamides of polyenic acrolydes
PL142847B1 (en) 1985-10-22 1987-12-31 Method of obtaining novel derivatives of n-/n,n-dimethylamino/-acyl antibiotics from the grouf of polyenic macrolydes
GB8829592D0 (en) 1988-12-19 1989-02-08 Beecham Group Plc Novel compounds
GB8829593D0 (en) 1988-12-19 1989-02-08 Beecham Group Plc Novel compounds
GB9203476D0 (en) 1992-02-19 1992-04-08 Smithkline Beecham Plc Novel compounds
PL180253B1 (en) 1995-05-13 2001-01-31 Politechnika Gdanska N-methyl n-glycoside derivatives of methyl esters of antibiotic from the group of polyene macrolydes and their salts, method of obtaining them and using them in medical care
US5942495A (en) * 1996-05-10 1999-08-24 Btg International Limited Antibiotics
US5981721A (en) 1997-10-23 1999-11-09 Karykion Corporation Polyene macrolide schiff bases, their alkyl esters and processes for preparing polyene macrolide alkyl ester salts thereof
FR2776927B1 (en) 1998-04-07 2002-07-05 Univ Paris Curie COMPOSITIONS FOR VECTORIZING MOLECULES
CA2394833A1 (en) * 2000-01-14 2001-07-19 Binh T. Dang Derivatives of polyene macrolides and preparation and use thereof
US6413537B1 (en) 2000-03-10 2002-07-02 Wisconsin Alumni Research Foundation Nystatin formulation having reduced toxicity
US6664241B2 (en) 2000-05-31 2003-12-16 Micrologix Biotech Inc. Water-soluble amide derivatives of polyene macrolides and preparation and uses thereof
EP1987049A1 (en) 2006-02-23 2008-11-05 ETH Zürich Amphotericin derivatives
PL210774B1 (en) 2006-06-19 2012-02-29 Politechnika Gdanska Spatially hospheric N-amineacyl derivatives of amphotercin B, the manner of obtaining them and application for fighting of fungicidal microorganisms
JP2010534688A (en) * 2007-07-30 2010-11-11 上海医薬工業研究院 Polyene antibiotic diester compounds

Also Published As

Publication number Publication date
US20150045316A1 (en) 2015-02-12
US9447136B2 (en) 2016-09-20
WO2013132014A1 (en) 2013-09-12
EP2852601A1 (en) 2015-04-01

Similar Documents

Publication Publication Date Title
IN2014DN10551A (en)
PH12018502747A1 (en) Boronic acid derivatives and therapeutic uses thereof
MX2015008627A (en) Boronic acid derivatives and therapeutic uses thereof.
MX2016016666A (en) Boronic acid derivatives and therapeutic uses thereof.
MX2016015093A (en) Boronic acid derivatives and therapeutic uses thereof.
MX2015008628A (en) Boronic acid derivatives and therapeutic uses thereof.
MY173843A (en) Amidine substituted ?-lactam compounds, their preparation and use as antibacterial agents
GB201106743D0 (en) Novel compounds
MX368258B (en) Cytotoxic and anti-mitotic compounds, and methods of using the same.
IN2015DN03998A (en)
EP3034082A4 (en) Pharmaceutical composition for treating or preventing neuropsychitric disease, containing flavone-6-c-glucose derivatives as active ingredients
PH12015502118A1 (en) Pyridin-4-yl derivatives
PH12015501175A1 (en) Substituted pyridopyrazines as syk inhibitors
PH12014502743A1 (en) Carbamate/urea derivatives
PH12015502632A1 (en) Cxcr7 receptor modulators
PH12018501709A1 (en) Naphthridinedione derivatives
MX368635B (en) Tricyclic piperidine compounds.
EP2871187A4 (en) Novel compound or pharmaceutically acceptable salt thereof, and pharmaceutical composition containing same as active ingredient
MX363622B (en) New macrocyclic amidinourea derivatives, methods of preparation and uses thereof as chitinase inhibitors.
IN2015DN00950A (en)
IN2014DN07481A (en)
MX2014004210A (en) 2-oxo-piperidinyl derivatives.
MX2015015251A (en) Quinolone derivatives.
NZ719215A (en) Pharmaceutical compositions comprising antibacterial agents
PL401345A1 (en) Camptothecin derivatives, their preparation and use