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IN2014DN06817A - - Google Patents

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Publication number
IN2014DN06817A
IN2014DN06817A IN6817DEN2014A IN2014DN06817A IN 2014DN06817 A IN2014DN06817 A IN 2014DN06817A IN 6817DEN2014 A IN6817DEN2014 A IN 6817DEN2014A IN 2014DN06817 A IN2014DN06817 A IN 2014DN06817A
Authority
IN
India
Prior art keywords
support member
macropores
biologies
delivery
certain embodiments
Prior art date
Application number
Inventor
John A Chickosky
Charles H Honeyman
Molly S Mcglaughlin
Amro Ragheb
Original Assignee
Natrix Separations Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Natrix Separations Inc filed Critical Natrix Separations Inc
Publication of IN2014DN06817A publication Critical patent/IN2014DN06817A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Described are composite materials and methods of making and using them for the storage and delivery of unstable drugs or biologies. In certain embodiments the composite material comprises a support member comprising a plurality of pores extending through the support member; a macroporous cross linked gel comprising a plurality of macropores; a therapeutic agent; and a stabilizing agent.
IN6817DEN2014 2012-01-19 2013-01-18 IN2014DN06817A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261588312P 2012-01-19 2012-01-19
PCT/US2013/022057 WO2013109825A1 (en) 2012-01-19 2013-01-18 Chromatographic media for storage and delivery of therapeutic biologics and small molecules

Publications (1)

Publication Number Publication Date
IN2014DN06817A true IN2014DN06817A (en) 2015-05-22

Family

ID=48797397

Family Applications (1)

Application Number Title Priority Date Filing Date
IN6817DEN2014 IN2014DN06817A (en) 2012-01-19 2013-01-18

Country Status (10)

Country Link
US (2) US20130189322A1 (en)
EP (1) EP2804634B1 (en)
JP (2) JP6552822B2 (en)
KR (1) KR102113296B1 (en)
AU (1) AU2013209620B2 (en)
CA (2) CA3124806C (en)
DK (1) DK2804634T3 (en)
ES (1) ES2750211T3 (en)
IN (1) IN2014DN06817A (en)
WO (1) WO2013109825A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11628381B2 (en) 2012-09-17 2023-04-18 W.R. Grace & Co. Conn. Chromatography media and devices
CN105358565B (en) 2013-07-25 2020-02-07 生物辐射实验室股份有限公司 Porous matrix protein delivery and functional enhancement
FR3012978A1 (en) * 2013-11-12 2015-05-15 Biocarecell BIOCOMPATIBLE FILTER AND METHOD FOR MANUFACTURING BIOCOMPATIBLE FILTER
PL3094390T3 (en) 2014-01-16 2021-12-06 W.R. Grace & Co. - Conn. Affinity chromatography media and chromatography devices
US11389783B2 (en) 2014-05-02 2022-07-19 W.R. Grace & Co.-Conn. Functionalized support material and methods of making and using functionalized support material
IS3008B (en) * 2014-05-14 2018-12-15 Calor ehf A peptide or protein stabilizing formulation
JP2018517559A (en) 2015-06-05 2018-07-05 ダブリュー・アール・グレース・アンド・カンパニー−コーンＷ Ｒ Ｇｒａｃｅ ＆ Ｃｏ−Ｃｏｎｎ Adsorbing bioprocess clarifier and method for producing and using the same
US20210379186A1 (en) * 2018-04-16 2021-12-09 Merck Patent Gmbh Additives for protein formulations to improve thermal stability

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5059654A (en) * 1983-02-14 1991-10-22 Cuno Inc. Affinity matrices of modified polysaccharide supports
DE3682047D1 (en) * 1985-07-09 1991-11-21 Quadrant Bioresources Ltd PROTECTION OF PROTEINS AND SIMILAR.
CA2073511A1 (en) * 1990-11-14 1992-05-29 Matthew R. Callstrom Conjugates of poly(vinylsaccharide) with proteins for the stabilization of proteins
US5159049A (en) * 1991-04-22 1992-10-27 Allen Robert C Method for stabilizing polyacrylamide gels
US5583162A (en) * 1994-06-06 1996-12-10 Biopore Corporation Polymeric microbeads and method of preparation
US6284282B1 (en) * 1998-04-29 2001-09-04 Genentech, Inc. Method of spray freeze drying proteins for pharmaceutical administration
SE9904475D0 (en) * 1999-12-08 1999-12-08 Artursson Nucleic acid delivery system
US6896894B2 (en) * 2001-10-30 2005-05-24 Battelle Memorial Institute Proteins stabilized with polysaccharide gums
AU2003217367B2 (en) * 2002-02-08 2005-09-08 Alkermes Controlled Therapeutics, Inc. Polymer-based compositions for sustained release
US20040137004A1 (en) * 2002-03-19 2004-07-15 Glenn Gregory M Patch for transcutaneous immunization
US6666281B2 (en) * 2002-03-19 2003-12-23 Deere & Company Bearing guard for a ground-working implement
EP2143482A1 (en) 2003-02-19 2010-01-13 Natrix Separations Inc. Composite materials comprising supported porous gels
US7785769B2 (en) * 2003-07-25 2010-08-31 The United States of America as reprsented by the Secretary of the Navy Immobilization of oligonucleotides and proteins in sugar-containing hydrogels
CA2558859C (en) 2004-04-08 2014-02-04 Mcmaster University Membrane stacks
ATE441669T1 (en) * 2004-05-24 2009-09-15 Genvault Corp STABLE STORAGE OF PROTEIN AND STABLE STORAGE OF NUCLEIC ACID IN RECOVERABLE FORM
US8133840B2 (en) * 2004-06-07 2012-03-13 Natrix Separations Inc. Stable composite material comprising supported porous gels

Also Published As

Publication number Publication date
KR20140117529A (en) 2014-10-07
ES2750211T3 (en) 2020-03-25
JP6552822B2 (en) 2019-07-31
AU2013209620B2 (en) 2017-06-15
CA3124806C (en) 2023-09-26
AU2013209620A1 (en) 2014-08-28
CA3124806A1 (en) 2013-07-27
WO2013109825A1 (en) 2013-07-25
KR102113296B1 (en) 2020-06-02
EP2804634A4 (en) 2015-07-22
CA2861932A1 (en) 2013-07-27
CA2861932C (en) 2021-09-14
DK2804634T3 (en) 2019-11-04
US20130189322A1 (en) 2013-07-25
JP2019011341A (en) 2019-01-24
EP2804634B1 (en) 2019-08-28
EP2804634A1 (en) 2014-11-26
JP2015504092A (en) 2015-02-05
US20200069602A1 (en) 2020-03-05

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