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IN168119B - - Google Patents

Info

Publication number
IN168119B
IN168119B IN837/CAL/87A IN837CA1987A IN168119B IN 168119 B IN168119 B IN 168119B IN 837CA1987 A IN837CA1987 A IN 837CA1987A IN 168119 B IN168119 B IN 168119B
Authority
IN
India
Prior art keywords
ifosfamide
weight
hexitol
optionally
parts
Prior art date
Application number
IN837/CAL/87A
Inventor
Dieter Sauerbier
Uwe Peter Dammann
Otto Isaac
Original Assignee
Asta Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Pharma Ag filed Critical Asta Pharma Ag
Publication of IN168119B publication Critical patent/IN168119B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cephalosporin Compounds (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Control Of El Displays (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Indole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Amplifiers (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1. A lyophilized preparation consisting of ifosfamide and 0.1 to 17 parts by weight hexitol per part by weight ifosfamide and, optionally, other standard pharmaceutical auxiliaries.
IN837/CAL/87A 1986-10-31 1987-10-26 IN168119B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3637089 1986-10-31

Publications (1)

Publication Number Publication Date
IN168119B true IN168119B (en) 1991-02-09

Family

ID=6312873

Family Applications (1)

Application Number Title Priority Date Filing Date
IN837/CAL/87A IN168119B (en) 1986-10-31 1987-10-26

Country Status (25)

Country Link
EP (1) EP0265812B1 (en)
JP (1) JPS63159319A (en)
KR (1) KR900003491B1 (en)
AT (1) ATE55250T1 (en)
AU (1) AU598602B2 (en)
CA (1) CA1314231C (en)
DD (1) DD262582A5 (en)
DE (1) DE3764235D1 (en)
DK (1) DK169308B1 (en)
EG (1) EG18333A (en)
ES (1) ES2017982B3 (en)
FI (1) FI87140C (en)
GE (1) GEP19971025B (en)
GR (1) GR3000708T3 (en)
HU (1) HU197987B (en)
IL (1) IL84312A (en)
IN (1) IN168119B (en)
LV (1) LV10051B (en)
MX (1) MX8958A (en)
NO (1) NO873860L (en)
PT (1) PT86032B (en)
RU (1) RU1836079C (en)
UA (1) UA11075A (en)
YU (1) YU197387A (en)
ZA (1) ZA878183B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2040394T3 (en) * 1988-03-19 1993-10-16 Asta Medica Aktiengesellschaft PROCEDURE FOR PREPARING A LYOPHILIZED MATERIAL OF IFOSFAMIDE AND MESNA.
US5227373A (en) * 1991-10-23 1993-07-13 Bristol-Myers Squibb Co. Lyophilized ifosfamide compositions
WO1995007083A1 (en) * 1993-09-10 1995-03-16 F.H. Faulding & Co. Limited Ifosfamide lyophilisate composition
DE19529057B4 (en) * 1995-08-08 2007-12-13 Baxter Healthcare S.A. Ifosfamide lyophilizate preparations
EA003864B1 (en) * 1998-03-03 2003-10-30 ШИОНОГИ энд КО.,ЛТД. COMPOSITION AND METHOD OF PREPARING OF PHARMACEUTICAL FORMULATION, LYOPHILIZED COMPOSITION AND USE OF IT, METHOD OF INHIBITING sPLA2-MEDIATED RELEASE OF FATTY ACID, METHOD OF TREATING A MAMMALS, METHOD OF TREATMENT OR PREVENTING SEPSIS, SEALED CONTAINER
US20050272698A1 (en) * 2002-09-05 2005-12-08 Daftary Gautam V Liquid stable composition of oxazaphosphorine with mesna
WO2004050012A2 (en) * 2002-12-02 2004-06-17 Bharat Serums And Vaccines Ltd Ifosfamide compositions for parenteral administration and a process for their preparation
US8436190B2 (en) * 2005-01-14 2013-05-07 Cephalon, Inc. Bendamustine pharmaceutical compositions
BRPI0715279A2 (en) * 2006-09-29 2013-06-11 Infa Sa packaging system, packaging system for a pharmaceutical composition, method for transferring a pharmaceutical composition for intravenous infusion administration, use of a packaging system, intravenous access parenteral drug delivery kit and parenteral administration kit of active principles
WO2016087001A1 (en) * 2014-12-04 2016-06-09 Huawei Technologies Co., Ltd. Load allocation in a data communication network

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3732340A (en) * 1966-07-11 1973-05-08 Asta Werke Ag Chem Fab N',o-propylene phosphoric acid ester diamides
DE2750207A1 (en) * 1977-05-09 1978-11-16 Walton J Smith Anhydrous compsn. prodn. by freeze drying hydrated, hydrolysable prod. - esp. aspirin or aspirin salt solns.
EP0083439B1 (en) * 1981-12-31 1989-07-26 ASTA Pharma AG 4-sulfido-oxaza phosphorines and their use in the treatment of cancer, and in immunosuppression
US4537883A (en) * 1982-11-12 1985-08-27 Mead Johnson & Company Lyophilized cyclophosphamide

Also Published As

Publication number Publication date
KR880004814A (en) 1988-06-27
LV10051B (en) 1995-06-20
DE3764235D1 (en) 1990-09-13
PT86032A (en) 1987-11-01
NO873860L (en) 1988-05-02
FI874727A (en) 1988-05-01
RU1836079C (en) 1993-08-23
NO873860D0 (en) 1987-09-15
JPH0543684B2 (en) 1993-07-02
FI874727A0 (en) 1987-10-27
DK569687A (en) 1988-05-01
GR3000708T3 (en) 1991-10-10
CA1314231C (en) 1993-03-09
FI87140B (en) 1992-08-31
DK169308B1 (en) 1994-10-10
AU8052987A (en) 1988-05-05
ATE55250T1 (en) 1990-08-15
DK569687D0 (en) 1987-10-30
EP0265812A1 (en) 1988-05-04
MX8958A (en) 1993-12-01
GEP19971025B (en) 1997-04-06
LV10051A (en) 1994-05-10
ES2017982B3 (en) 1991-03-16
FI87140C (en) 1992-12-10
HUT44932A (en) 1988-05-30
IL84312A (en) 1991-11-21
YU197387A (en) 1988-12-31
ZA878183B (en) 1988-05-02
PT86032B (en) 1990-08-31
KR900003491B1 (en) 1990-05-21
HU197987B (en) 1989-07-28
EP0265812B1 (en) 1990-08-08
EG18333A (en) 1993-12-30
DD262582A5 (en) 1988-12-07
IL84312A0 (en) 1988-03-31
UA11075A (en) 1996-12-25
AU598602B2 (en) 1990-06-28
JPS63159319A (en) 1988-07-02

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